Case for Diagnosis
Violaceous Papules on the Dorsum of the Hand
Pápulas violáceas en el dorso de la mano
Read
7361
Timeswas read the article
2383
Total PDF
4978
Total HTML
Share statistics
array:24 [ "pii" => "S1578219012002818" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.01.020" "estado" => "S300" "fechaPublicacion" => "2012-11-01" "aid" => "610" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2011" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:825-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3183 "formatos" => array:3 [ "EPUB" => 46 "HTML" => 2476 "PDF" => 661 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731012001858" "issn" => "00017310" "doi" => "10.1016/j.ad.2012.01.018" "estado" => "S300" "fechaPublicacion" => "2012-11-01" "aid" => "610" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:825-6" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4369 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 3084 "PDF" => 1283 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Casos para el Diagnóstico</span>" "titulo" => "Pápulas violáceas en el dorso de la mano" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "825" "paginaFinal" => "826" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Violaceous Papules on the Dorsum of the Hand" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 712 "Ancho" => 950 "Tamanyo" => 193456 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Tinción inmunohistoquímica CD31 x10.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "B. García-García, L. Palacios-García, B. Vivanco-Allende" "autores" => array:3 [ 0 => array:2 [ "nombre" => "B." "apellidos" => "García-García" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Palacios-García" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Vivanco-Allende" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S1578219012002818" "doi" => "10.1016/j.adengl.2012.01.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002818?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012001858?idApp=UINPBA000044" "url" => "/00017310/0000010300000009/v1_201304241717/S0001731012001858/v1_201304241717/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S157821901200282X" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.04.015" "estado" => "S300" "fechaPublicacion" => "2012-11-01" "aid" => "639" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:827-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 4704 "formatos" => array:3 [ "EPUB" => 42 "HTML" => 3717 "PDF" => 945 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Asymptomatic Lesion on the Nasal Ala" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "827" "paginaFinal" => "828" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lesión asintomática en ala nasal" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1492 "Ancho" => 1187 "Tamanyo" => 177504 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification ×20.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "L.C. Arango-Duque, M. Yuste-Chaves, M. Rodríguez-González" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L.C." "apellidos" => "Arango-Duque" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Yuste-Chaves" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Rodríguez-González" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731012002232" "doi" => "10.1016/j.ad.2012.04.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731012002232?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901200282X?idApp=UINPBA000044" "url" => "/15782190/0000010300000009/v1_201304241357/S157821901200282X/v1_201304241357/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219012002806" "issn" => "15782190" "doi" => "10.1016/j.adengl.2011.07.010" "estado" => "S300" "fechaPublicacion" => "2012-11-01" "aid" => "532" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "article" "crossmark" => 0 "subdocumento" => "sco" "cita" => "Actas Dermosifiliogr. 2012;103:820-3" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5136 "formatos" => array:3 [ "EPUB" => 41 "HTML" => 4246 "PDF" => 849 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Perianal Ulcers on a Segmental Hemangioma With Minimal or Arrested Growth" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "820" "paginaFinal" => "823" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Úlceras perianales sobre hemangioma con crecimiento mínimo o detenido segmentario" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2275 "Ancho" => 1252 "Tamanyo" => 176922 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Hemangioma with minimal or arrested growth. There is a pale, erythematous macule with multiple fine telangiectasias.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Lanoel, V. Tosi, M. Bocian, F. Lubieniecki, S.B. Poblete, H.O. García, A.M. Pierini" "autores" => array:7 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Lanoel" ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Tosi" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Bocian" ] 3 => array:2 [ "nombre" => "F." "apellidos" => "Lubieniecki" ] 4 => array:2 [ "nombre" => "S.B." "apellidos" => "Poblete" ] 5 => array:2 [ "nombre" => "H.O." "apellidos" => "García" ] 6 => array:2 [ "nombre" => "A.M." "apellidos" => "Pierini" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731011005254" "doi" => "10.1016/j.ad.2011.07.018" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731011005254?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002806?idApp=UINPBA000044" "url" => "/15782190/0000010300000009/v1_201304241357/S1578219012002806/v1_201304241357/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Violaceous Papules on the Dorsum of the Hand" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "825" "paginaFinal" => "826" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "B. García-García, L. Palacios-García, B. Vivanco-Allende" "autores" => array:3 [ 0 => array:4 [ "nombre" => "B." "apellidos" => "García-García" "email" => array:1 [ 0 => "begarciagarcia@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "L." "apellidos" => "Palacios-García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "B." "apellidos" => "Vivanco-Allende" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Central de Asturias, Oviedo, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Universitario Central de Asturias, Oviedo, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pápulas violáceas en el dorso de la mano" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 706 "Ancho" => 951 "Tamanyo" => 124618 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Medical History</span><p id="par0005" class="elsevierStylePara elsevierViewall">We report the case of a 70-year-old woman with no relevant past history who presented 2 lesions on the dorsum of the right hand that had appeared 6 months earlier. The lesions were asymptomatic and had developed gradually.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Physical Examination</span><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed 2 violaceous papules located close together on the dorsum of the right hand and that measured 1<span class="elsevierStyleHsp" style=""></span>cm and 0.5<span class="elsevierStyleHsp" style=""></span>cm in diameter (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The lesions had a smooth surface and firm consistency and were not tender to palpation.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Histopathology</span><p id="par0015" class="elsevierStylePara elsevierViewall">A punch biopsy was taken from 1 of the lesions. Histology showed a normal epidermis, but in the middle and deep dermis there was a disorganized proliferation of mature eccrine glands and ducts with interspersed mature adipocytes (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). In addition, there were numerous vascular structures with walls of varying thickness that were positive for CD31 on immunohistochemistry (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleBold">What Is Your Diagnosis?</span></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Diagnosis</span><p id="par0025" class="elsevierStylePara elsevierViewall">Eccrine angiomatous hamartoma</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Clinical Course and Treatment</span><p id="par0030" class="elsevierStylePara elsevierViewall">As the lesions showed persistent growth, they were excised.</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Comment</span><p id="par0035" class="elsevierStylePara elsevierViewall">Eccrine angiomatous hamartoma (EAH) is a rare benign skin tumor combining eccrine and vascular elements. The first case was described by Lotzbeck in 1859, but the term EAH was later proposed by Hyman in 1968.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">EAH typically appears in early childhood, often in congenital form, and during later stages of childhood or even puberty. While infrequent, there have been reports of onset in adults, as in our patient.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Clinically the lesions are usually single, though multiple lesions are observed, and they typically arise on the limbs (80%), although they have been described on other areas of the body. Morphologically, the lesions may consist of papules, nodules, or plaques that can be erythematous, violaceous, bluish, yellowish, or even skin colored. Although EAH is normally asymptomatic, the 2 most common symptoms are pain (42%) and hyperhidrosis (34%).<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Histopathology of EAH reveals a proliferation of mature eccrine glands in the middle and deep dermis in close association with dilated or collapsed angiomatous channels with thin, clearly differentiated walls. Some histopathologic variants also include pilar structures, apocrine glands, lipomatous foci, lymph vessels, and, rarely, bone.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The clinical differential diagnosis must include vascular malformations, smooth muscle hamartoma, juvenile xanthogranuloma, glomus tumor, tufted angioma, blue rubber bleb nevus syndrome, and macular telangiectatic mastocytosis.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> The most relevant disorders in the histologic differential diagnosis are sudoriparous angioma, which involves dilation rather than proliferation of the eccrine glands, and eccrine nevus, in which angiomatous proliferation is absent.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">As EAH is benign and occasionally presents spontaneous involution, it does not require aggressive measures. However, in patients with painful lesions or cosmetic concerns, surgical excision is the only definitive treatment.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:7 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Medical History" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Physical Examination" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Histopathology" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Diagnosis" ] 4 => array:2 [ "identificador" => "sec0025" "titulo" => "Clinical Course and Treatment" ] 5 => array:2 [ "identificador" => "sec0030" "titulo" => "Comment" ] 6 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: García-García B, et al. Pápulas violáceas en el dorso de la mano. Actas Dermosifiliogr. 2012;103:825-6.</p>" ] ] "multimedia" => array:3 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 706 "Ancho" => 951 "Tamanyo" => 124618 ] ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 714 "Ancho" => 952 "Tamanyo" => 247411 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Hematoxylin-eosin, original magnification<span class="elsevierStyleHsp" style=""></span>×10.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 713 "Ancho" => 952 "Tamanyo" => 175678 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">CD31 immunohistochemical staining, original magnification<span class="elsevierStyleHsp" style=""></span>×10.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eccrine angiomatous hamartoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.B. Hyman" 1 => "H. Harris" 2 => "M.H. Brownstein" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "N Y State J Med" "fecha" => "1968" "volumen" => "68" "paginaInicial" => "2803" "paginaFinal" => "2806" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5247013" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Late-onset eccrine angiomatous hamartoma on the forehead" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "E. Jeong" 1 => "H.J. Park" 2 => "S.T. Oh" 3 => "J.Y. Lee" 4 => "B.K. Cho" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2004.02397.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2006" "volumen" => "45" "paginaInicial" => "598" "paginaFinal" => "599" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16700801" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Hamartoma angiomatoso ecrino: presentación de dos casos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Batalla" 1 => "E. Rosón" 2 => "A. Flórez" 3 => "A. Troncoso" 4 => "C. de la Torre" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2010.08.006" "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2011" "volumen" => "102" "paginaInicial" => "289" "paginaFinal" => "292" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21453905" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eccrine angiomatous hamartoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.T. Pelle" 1 => "H.B. Pride" 2 => "W.B. Tyler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "429" "paginaFinal" => "435" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12196755" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eccrine angiomatous hamartoma (nevus): immunohistochemical findings and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.L. Sulica" 1 => "G.F. Kao" 2 => "V.I. Sulica" 3 => "N.S. Penneys" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cutan Pathol" "fecha" => "1994" "volumen" => "21" "paginaInicial" => "71" "paginaFinal" => "75" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7514619" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eccrine angiomatous hamartoma: a case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.T. Martinelli" 1 => "J.A. Tschen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cutis" "fecha" => "2003" "volumen" => "71" "paginaInicial" => "449" "paginaFinal" => "455" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12839255" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010300000009/v1_201304241357/S1578219012002818/v1_201304241357/en/main.assets" "Apartado" => array:4 [ "identificador" => "6154" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Case for Diagnosis" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010300000009/v1_201304241357/S1578219012002818/v1_201304241357/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012002818?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 12 | 9 | 21 |
| 2024 October | 63 | 44 | 107 |
| 2024 September | 83 | 28 | 111 |
| 2024 August | 85 | 49 | 134 |
| 2024 July | 69 | 34 | 103 |
| 2024 June | 81 | 36 | 117 |
| 2024 May | 81 | 35 | 116 |
| 2024 April | 58 | 21 | 79 |
| 2024 March | 75 | 34 | 109 |
| 2024 February | 52 | 34 | 86 |
| 2024 January | 55 | 32 | 87 |
| 2023 December | 54 | 20 | 74 |
| 2023 November | 73 | 30 | 103 |
| 2023 October | 63 | 25 | 88 |
| 2023 September | 61 | 36 | 97 |
| 2023 August | 41 | 18 | 59 |
| 2023 July | 41 | 35 | 76 |
| 2023 June | 38 | 37 | 75 |
| 2023 May | 61 | 30 | 91 |
| 2023 April | 42 | 40 | 82 |
| 2023 March | 48 | 48 | 96 |
| 2023 February | 43 | 28 | 71 |
| 2023 January | 53 | 42 | 95 |
| 2022 December | 45 | 53 | 98 |
| 2022 November | 25 | 20 | 45 |
| 2022 October | 21 | 29 | 50 |
| 2022 September | 23 | 30 | 53 |
| 2022 August | 25 | 30 | 55 |
| 2022 July | 19 | 31 | 50 |
| 2022 June | 16 | 28 | 44 |
| 2022 May | 72 | 38 | 110 |
| 2022 April | 48 | 37 | 85 |
| 2022 March | 52 | 50 | 102 |
| 2022 February | 26 | 24 | 50 |
| 2022 January | 39 | 41 | 80 |
| 2021 December | 35 | 49 | 84 |
| 2021 November | 45 | 43 | 88 |
| 2021 October | 49 | 40 | 89 |
| 2021 September | 28 | 42 | 70 |
| 2021 August | 32 | 28 | 60 |
| 2021 July | 33 | 33 | 66 |
| 2021 June | 32 | 27 | 59 |
| 2021 May | 42 | 25 | 67 |
| 2021 April | 61 | 53 | 114 |
| 2021 March | 66 | 27 | 93 |
| 2021 February | 49 | 25 | 74 |
| 2021 January | 26 | 19 | 45 |
| 2020 December | 29 | 15 | 44 |
| 2020 November | 17 | 18 | 35 |
| 2020 October | 25 | 6 | 31 |
| 2020 September | 21 | 12 | 33 |
| 2020 August | 23 | 17 | 40 |
| 2020 July | 34 | 16 | 50 |
| 2020 June | 28 | 25 | 53 |
| 2020 May | 22 | 17 | 39 |
| 2020 April | 35 | 16 | 51 |
| 2020 March | 26 | 12 | 38 |
| 2020 February | 2 | 1 | 3 |
| 2020 January | 4 | 0 | 4 |
| 2019 December | 8 | 1 | 9 |
| 2019 November | 4 | 1 | 5 |
| 2019 October | 0 | 1 | 1 |
| 2019 September | 8 | 6 | 14 |
| 2019 August | 4 | 0 | 4 |
| 2019 July | 4 | 6 | 10 |
| 2019 June | 5 | 44 | 49 |
| 2019 May | 4 | 20 | 24 |
| 2019 April | 2 | 12 | 14 |
| 2019 March | 2 | 7 | 9 |
| 2019 February | 2 | 5 | 7 |
| 2019 January | 2 | 1 | 3 |
| 2018 December | 7 | 3 | 10 |
| 2018 November | 1 | 2 | 3 |
| 2018 October | 3 | 0 | 3 |
| 2018 September | 6 | 0 | 6 |
| 2018 May | 0 | 1 | 1 |
| 2018 March | 14 | 4 | 18 |
| 2018 February | 76 | 4 | 80 |
| 2018 January | 56 | 12 | 68 |
| 2017 December | 69 | 8 | 77 |
| 2017 November | 44 | 6 | 50 |
| 2017 October | 55 | 6 | 61 |
| 2017 September | 44 | 12 | 56 |
| 2017 August | 46 | 20 | 66 |
| 2017 July | 48 | 10 | 58 |
| 2017 June | 53 | 18 | 71 |
| 2017 May | 51 | 12 | 63 |
| 2017 April | 55 | 9 | 64 |
| 2017 March | 56 | 43 | 99 |
| 2017 February | 40 | 12 | 52 |
| 2017 January | 38 | 11 | 49 |
| 2016 December | 49 | 8 | 57 |
| 2016 November | 68 | 9 | 77 |
| 2016 October | 85 | 10 | 95 |
| 2016 September | 80 | 13 | 93 |
| 2016 August | 74 | 10 | 84 |
| 2016 July | 52 | 10 | 62 |
| 2016 June | 12 | 16 | 28 |
| 2016 May | 6 | 9 | 15 |
| 2016 April | 4 | 1 | 5 |
| 2016 March | 11 | 2 | 13 |
| 2016 February | 10 | 10 | 20 |
| 2016 January | 5 | 1 | 6 |
| 2015 December | 6 | 3 | 9 |
| 2015 November | 15 | 8 | 23 |
| 2015 October | 11 | 11 | 22 |
| 2015 September | 7 | 6 | 13 |
| 2015 August | 12 | 1 | 13 |
| 2015 July | 77 | 13 | 90 |
| 2015 June | 58 | 7 | 65 |
| 2015 May | 88 | 9 | 97 |
| 2015 April | 83 | 20 | 103 |
| 2015 March | 65 | 7 | 72 |
| 2015 February | 67 | 11 | 78 |
| 2015 January | 58 | 11 | 69 |
| 2014 December | 55 | 9 | 64 |
| 2014 November | 51 | 7 | 58 |
| 2014 October | 32 | 4 | 36 |
| 2014 September | 22 | 2 | 24 |
| 2014 August | 26 | 0 | 26 |
| 2014 July | 26 | 1 | 27 |
| 2014 June | 32 | 5 | 37 |
| 2014 May | 49 | 2 | 51 |
| 2014 April | 24 | 2 | 26 |
| 2014 March | 28 | 10 | 38 |
| 2014 February | 39 | 9 | 48 |
| 2014 January | 32 | 6 | 38 |
| 2013 December | 32 | 7 | 39 |
| 2013 November | 31 | 8 | 39 |
| 2013 October | 21 | 7 | 28 |
| 2013 September | 23 | 3 | 26 |
| 2013 August | 21 | 12 | 33 |
| 2013 July | 10 | 16 | 26 |
| 2013 June | 4 | 8 | 12 |
| 2013 May | 10 | 8 | 18 |
| 2013 April | 12 | 8 | 20 |
| 2013 March | 18 | 7 | 25 |
| 2013 February | 25 | 8 | 33 |
| 2013 January | 18 | 4 | 22 |
| 2012 December | 20 | 5 | 25 |
Show all
