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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Multinucleate cell angiohistiocytoma &#40;MCAH&#41; is a rare entity that takes the form of a benign dermatologic proliferation formed by small blood vessels and multinucleate mesenchymal cells&#46; These lesions are probably underdiagnosed because of their similarity to other disorders&#44; such as dermatofibroma&#44; and because of their benign&#44; asymptomatic nature&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 35-year-old woman in the 36th week of her 4th pregnancy&#46; The child born as a result of her second pregnancy had died 24<span class="elsevierStyleHsp" style=""></span>hours post partum&#46; The woman had been visiting our department for many years due to multiple asymptomatic lesions on her trunk and extremities&#59; the lesions first appeared during the first pregnancy and had increased in number over the course of the subsequent pregnancies&#46; The physical examination revealed more than 100 round maculopapular lesions with diameters ranging between 2 and 8<span class="elsevierStyleHsp" style=""></span>mm&#59; the lesions were erythematous-violaceous with a smooth surface and were distributed unevenly across the trunk and extremities &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Dermoscopy showed a fine pigmented reticular pattern around the borders and a whitish central patch &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#59; these findings were compatible with clinical suspicion of multiple eruptive dermatofibroma&#46; Because this presentation of dermatofibroma has been associated with autoimmune disease&#44; an immunological study was performed&#46; The salient findings were the presence of anti-Ro 60 antibodies and antinuclear antibodies distributed in a speckled pattern&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Biopsy specimens of 2 papules revealed poorly defined lesions involving the full thickness of the dermis&#46; Histology showed that the papules consisted of numerous small blood vessels with prominent endothelia distributed with no clear pattern throughout the dermal collagen&#46; Other findings included scant perivascular histiocytes and lymphocytes and multinucleate mesenchymal cells characterized by fewer than 10 nuclei&#44; no abnormalities&#44; and a large cytoplasm with angular contours &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>a&#41;&#46; Immunohistochemical analysis showed estrogen receptor &#945; expression in some perivascular spindle-shaped cells &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>b&#41; and progesterone receptor expression in very few cells at the same location&#46; Immune staining was negative for hormone receptors in the multinucleate cells&#46; A diagnosis of generalized eruptive MCAH was reached&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The skin lesions were not treated because of the widespread nature of the outbreak&#46; The patient was referred to obstetrics because of the positive anti-Ro 60 result and the history of the death of the newborn child after her earlier pregnancy&#46; The neonate was monitored by the pediatrics department&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">MCAH is considered to be a dermal dendrocyte proliferation&#46; Some authors consider it to be a variant of dermatofibroma<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>&#59; as with dermatofibroma&#44; it is difficult to determine whether MCAH is a true neoplasm or a reactive process&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> MCAH presents in healthy persons and reported associations with other diseases appear to be coincidental&#46; Several factors support the idea that this is a reactive entity&#58; the fact that some patients present with multiple lesions&#44; the location of lesions in sites exposed to trauma and insect bites&#44; the absence of a familial association&#44; and the spontaneous regression reported in some cases&#46; A link to hormone factors has been suggested&#44; as these lesions present more frequently in women &#40;79&#37; of cases&#41; and have been associated with overexpression of estrogen receptor &#945;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Including our patient&#44; 5 cases of generalized MCAH have been reported to date&#58; 3 men and 2 women<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;7</span></a> aged between 24 and 56 years with no associated disease&#46; Of note in our case is the coincidence of the eruptive appearance of the lesions and each pregnancy&#44; and the finding of anti-Ro 60 antibodies with a history of the death of a newborn baby&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The dermoscopy findings concur with those reported in the literature<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> and are similar to the dermoscopy pattern of dermatofibroma&#46; Multiple eruptive dermatofibroma has been linked to an abnormal immune system&#46; In a review of 67 cases&#44; Zaccaria et al&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> found a link with intercurrent disease in 96&#37; of their cases&#44; 83&#37; of which were immune-deficient conditions&#46; Those authors therefore suggested that the multiple eruptive presentation of dermatofibroma might be a diagnostic marker for immunosuppressive conditions&#46; The cases reviewed included that reported by Stainforth and Goodfield<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> of a healthy woman who developed 9 dermatofibromas on the trunk during pregnancy&#59; the authors included pregnancy as a condition involving immune-system abnormality&#46; In light of our case&#44; we suggest that the multiple eruptive form of MCAH may bear similarities to pregnancy-associated dermatofibroma&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In conclusion&#44; we present the first case of generalized eruptive MCAH associated with every pregnancy in a woman who remained anti-Ro&#47;SSA-positive and who has had no other associated symptoms to date&#46; We suggest that this unique and rare clinical form of the disease may&#44; in the future&#44; be an indicator of an abnormal immune system and that it may support the association&#44; suggested by some authors&#44; of MCAH with hormone factors&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p></span>"
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                        "paginaFinal" => "322"
                        "link" => array:1 [
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                        "link" => array:1 [
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Case and Research Letters
Generalized Eruptive Multinucleate Cell Angiohistiocytoma in a Pregnant Woman: A Case Report and Review of the Literature
Angiohistiocitomas de células multinucleadas eruptivos y generalizados en una gestante. Presentación de un caso y revisión de la literatura
C.A. Villanuevaa,
Corresponding author
, J.C. Tardíob, A. Romero-Matéa, J. Borbujoa
a Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Madrid, Spain
b Servicio de Anatomía Patológica, Hospital Universitario de Fuenlabrada, Madrid, Spain
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    "titulo" => "Generalized Eruptive Multinucleate Cell Angiohistiocytoma in a Pregnant Woman&#58; A Case Report and Review of the Literature"
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        "titulo" => "Angiohistiocitomas de c&#233;lulas multinucleadas eruptivos y generalizados en una gestante&#46; Presentaci&#243;n de un caso y revisi&#243;n de la literatura"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A&#44; Multinucleate mesenchymal cells with angled cytoplasmic borders and small vessels with thickened walls and prominent endothelia located in the dermal collagen &#40;hematoxylin-eosin&#44; original magnification x400&#41;&#46; B&#44; Positive immune staining for estrogen receptor &#945; in perivascular spindle-shaped cells &#40;original magnification x400&#41;&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Multinucleate cell angiohistiocytoma &#40;MCAH&#41; is a rare entity that takes the form of a benign dermatologic proliferation formed by small blood vessels and multinucleate mesenchymal cells&#46; These lesions are probably underdiagnosed because of their similarity to other disorders&#44; such as dermatofibroma&#44; and because of their benign&#44; asymptomatic nature&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 35-year-old woman in the 36th week of her 4th pregnancy&#46; The child born as a result of her second pregnancy had died 24<span class="elsevierStyleHsp" style=""></span>hours post partum&#46; The woman had been visiting our department for many years due to multiple asymptomatic lesions on her trunk and extremities&#59; the lesions first appeared during the first pregnancy and had increased in number over the course of the subsequent pregnancies&#46; The physical examination revealed more than 100 round maculopapular lesions with diameters ranging between 2 and 8<span class="elsevierStyleHsp" style=""></span>mm&#59; the lesions were erythematous-violaceous with a smooth surface and were distributed unevenly across the trunk and extremities &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; Dermoscopy showed a fine pigmented reticular pattern around the borders and a whitish central patch &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#59; these findings were compatible with clinical suspicion of multiple eruptive dermatofibroma&#46; Because this presentation of dermatofibroma has been associated with autoimmune disease&#44; an immunological study was performed&#46; The salient findings were the presence of anti-Ro 60 antibodies and antinuclear antibodies distributed in a speckled pattern&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Biopsy specimens of 2 papules revealed poorly defined lesions involving the full thickness of the dermis&#46; Histology showed that the papules consisted of numerous small blood vessels with prominent endothelia distributed with no clear pattern throughout the dermal collagen&#46; Other findings included scant perivascular histiocytes and lymphocytes and multinucleate mesenchymal cells characterized by fewer than 10 nuclei&#44; no abnormalities&#44; and a large cytoplasm with angular contours &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>a&#41;&#46; Immunohistochemical analysis showed estrogen receptor &#945; expression in some perivascular spindle-shaped cells &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>b&#41; and progesterone receptor expression in very few cells at the same location&#46; Immune staining was negative for hormone receptors in the multinucleate cells&#46; A diagnosis of generalized eruptive MCAH was reached&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The skin lesions were not treated because of the widespread nature of the outbreak&#46; The patient was referred to obstetrics because of the positive anti-Ro 60 result and the history of the death of the newborn child after her earlier pregnancy&#46; The neonate was monitored by the pediatrics department&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">MCAH is considered to be a dermal dendrocyte proliferation&#46; Some authors consider it to be a variant of dermatofibroma<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a>&#59; as with dermatofibroma&#44; it is difficult to determine whether MCAH is a true neoplasm or a reactive process&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> MCAH presents in healthy persons and reported associations with other diseases appear to be coincidental&#46; Several factors support the idea that this is a reactive entity&#58; the fact that some patients present with multiple lesions&#44; the location of lesions in sites exposed to trauma and insect bites&#44; the absence of a familial association&#44; and the spontaneous regression reported in some cases&#46; A link to hormone factors has been suggested&#44; as these lesions present more frequently in women &#40;79&#37; of cases&#41; and have been associated with overexpression of estrogen receptor &#945;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Including our patient&#44; 5 cases of generalized MCAH have been reported to date&#58; 3 men and 2 women<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#8211;7</span></a> aged between 24 and 56 years with no associated disease&#46; Of note in our case is the coincidence of the eruptive appearance of the lesions and each pregnancy&#44; and the finding of anti-Ro 60 antibodies with a history of the death of a newborn baby&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The dermoscopy findings concur with those reported in the literature<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> and are similar to the dermoscopy pattern of dermatofibroma&#46; Multiple eruptive dermatofibroma has been linked to an abnormal immune system&#46; In a review of 67 cases&#44; Zaccaria et al&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> found a link with intercurrent disease in 96&#37; of their cases&#44; 83&#37; of which were immune-deficient conditions&#46; Those authors therefore suggested that the multiple eruptive presentation of dermatofibroma might be a diagnostic marker for immunosuppressive conditions&#46; The cases reviewed included that reported by Stainforth and Goodfield<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> of a healthy woman who developed 9 dermatofibromas on the trunk during pregnancy&#59; the authors included pregnancy as a condition involving immune-system abnormality&#46; In light of our case&#44; we suggest that the multiple eruptive form of MCAH may bear similarities to pregnancy-associated dermatofibroma&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">In conclusion&#44; we present the first case of generalized eruptive MCAH associated with every pregnancy in a woman who remained anti-Ro&#47;SSA-positive and who has had no other associated symptoms to date&#46; We suggest that this unique and rare clinical form of the disease may&#44; in the future&#44; be an indicator of an abnormal immune system and that it may support the association&#44; suggested by some authors&#44; of MCAH with hormone factors&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p></span>"
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        "nota" => "<p class="elsevierStyleNotepara">Please cite this article as&#58; Villanueva CA&#44; et al&#46; Angiohistiocitomas de c&#233;lulas multinucleadas eruptivos y generalizados en una gestante&#46; Presentaci&#243;n de un caso y revisi&#243;n de la literatura&#46; Actas Dermosifiliogr&#46;2012&#59;103&#58;450-2&#46;</p>"
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              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Angiohistiocitoma de c&#233;lulas multinucleadas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46; Requena"
                            1 => "C&#46; Requena"
                            2 => "R&#46;O&#46; Pichardo"
                            3 => "O&#46;P&#46; Sangueza"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Monogr Dermatol"
                        "fecha" => "2004"
                        "volumen" => "17"
                        "paginaInicial" => "82"
                        "paginaFinal" => "85"
                      ]
                    ]
                  ]
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              ]
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            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Multinucleate cell angiohystiocitoma&#58; a fibrohistiocytic proliferation with increased mast cell numbers and vascular hyperplasia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "L&#46; Puig"
                            1 => "M&#46;T&#46; Fern&#225;ndez-Figueras"
                            2 => "I&#46; Bielsa"
                            3 => "B&#46; Lloveras"
                            4 => "A&#46; Alomar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Pathol"
                        "fecha" => "2002"
                        "volumen" => "29"
                        "paginaInicial" => "232"
                        "paginaFinal" => "237"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12028156"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estrogen receptor alpha overexpression in multinucleate cell angiohistiocytoma&#58; new insights into pathogenesis of a reactive process"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;M&#46; Cesinaro"
                            1 => "L&#46; Roncati"
                            2 => "A&#46; Maionara"
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                  ]
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                    0 => array:2 [
                      "doi" => "10.1097/DAD.0b013e3181d3ca49"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Dermatopathol"
                        "fecha" => "2010"
                        "volumen" => "32"
                        "paginaInicial" => "655"
                        "paginaFinal" => "659"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20644465"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Generalized multinucleate cell angiohistiocytoma"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "S&#46;N&#46; Chang"
                            1 => "H&#46;S&#46; Kim"
                            2 => "S&#46;C&#46; Kim"
                            3 => "W&#46;I&#46; Yang"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Am Acad Dermatol"
                        "fecha" => "1996"
                        "volumen" => "35"
                        "paginaInicial" => "320"
                        "paginaFinal" => "322"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8698916"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                0 => array:2 [
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                          "etal" => true
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                            0 => "S&#46; Leclerc"
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                            2 => "M&#46; Rybojad"
                            3 => "N&#46; Girszyn"
                            4 => "P&#46; Morel"
                            5 => "A&#46; Janin"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Dermatol Venereol"
                        "fecha" => "2005"
                        "volumen" => "132"
                        "paginaInicial" => "546"
                        "paginaFinal" => "549"
                        "link" => array:1 [
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                  "contribucion" => array:1 [
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                      "titulo" => "Novel case of generalized cell angiohistiocytoma"
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                            2 => "P&#46;J&#46; Green"
                            3 => "R&#46;D&#46; Tremaine"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Med Surg"
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                        "volumen" => "14"
                        "paginaInicial" => "178"
                        "paginaFinal" => "180"
                        "link" => array:1 [
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                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2010.08.008"
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                        "paginaInicial" => "231"
                        "paginaFinal" => "233"
                        "link" => array:1 [
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                0 => array:2 [
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                      "titulo" => "Multiple eruptive dermatofibromas and immunosuppression&#58; report of two cases and review of the literature"
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                    0 => array:2 [
                      "doi" => "10.1111/j.1365-4632.2008.03575.x"
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Dermatol"
                        "fecha" => "2008"
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Article information
ISSN: 15782190
Original language: English
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Idiomas
Actas Dermo-Sifiliográficas
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