Case and Research Letters
Frontal Fibrosing Alopecia: Dermoscopic Features
Alopecia frontal fibrosante. Hallazgos dermatoscópicos
Read
14237
Timeswas read the article
3196
Total PDF
11041
Total HTML
Share statistics
array:24 [ "pii" => "S157821901200073X" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.03.010" "estado" => "S300" "fechaPublicacion" => "2012-03-01" "aid" => "465" "copyright" => "Elsevier España, S.L. and AEDV" "copyrightAnyo" => "2010" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:167-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 6927 "formatos" => array:3 [ "EPUB" => 58 "HTML" => 5793 "PDF" => 1076 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0001731011003401" "issn" => "00017310" "doi" => "10.1016/j.ad.2011.01.018" "estado" => "S300" "fechaPublicacion" => "2012-03-01" "aid" => "465" "copyright" => "Elsevier España, S.L. y AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:167-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 7419 "formatos" => array:3 [ "EPUB" => 13 "HTML" => 5958 "PDF" => 1448 ] ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta científico-clínica</span>" "titulo" => "Alopecia frontal fibrosante. Hallazgos dermatoscópicos" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "167" "paginaFinal" => "168" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Frontal Fibrosing Alopecia: Dermoscopic Features" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 698 "Ancho" => 950 "Tamanyo" => 153909 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Mujer de 51 años con una placa de alopecia en banda en región fronto-temporal. Nótese la recesión de la línea de implantación del pelo.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "H. Mireles-Rocha, L.E. Sánchez-Dueñas, M. Hernández-Torres" "autores" => array:3 [ 0 => array:2 [ "nombre" => "H." "apellidos" => "Mireles-Rocha" ] 1 => array:2 [ "nombre" => "L.E." "apellidos" => "Sánchez-Dueñas" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Hernández-Torres" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S157821901200073X" "doi" => "10.1016/j.adengl.2012.03.010" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901200073X?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731011003401?idApp=UINPBA000044" "url" => "/00017310/0000010300000002/v1_201304241353/S0001731011003401/v1_201304241353/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S1578219012000741" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.03.011" "estado" => "S300" "fechaPublicacion" => "2012-03-01" "aid" => "466" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:169-70" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 7227 "formatos" => array:3 [ "EPUB" => 58 "HTML" => 5932 "PDF" => 1237 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Good Response of Hyperkeratotic Palmoplantar Psoriasis to Ustekinumab" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "169" "paginaFinal" => "170" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Psoriasis hiperqueratósica palmoplantar con excelente respuesta a ustekinumab" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1125 "Ancho" => 1500 "Tamanyo" => 149139 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Excellent response after 16 weeks’ treatment with ustekinumab.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Nuño-González, E. Gómez de la Fuente, F.J. Vicente-Martín, J.L. López-Estebaranz" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Nuño-González" ] 1 => array:2 [ "nombre" => "E." "apellidos" => "Gómez de la Fuente" ] 2 => array:2 [ "nombre" => "F.J." "apellidos" => "Vicente-Martín" ] 3 => array:2 [ "nombre" => "J.L." "apellidos" => "López-Estebaranz" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731011003413" "doi" => "10.1016/j.ad.2011.03.029" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731011003413?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012000741?idApp=UINPBA000044" "url" => "/15782190/0000010300000002/v1_201304241253/S1578219012000741/v1_201304241253/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S1578219012000728" "issn" => "15782190" "doi" => "10.1016/j.adengl.2012.03.009" "estado" => "S300" "fechaPublicacion" => "2012-03-01" "aid" => "464" "copyright" => "Elsevier España, S.L. and AEDV" "documento" => "simple-article" "crossmark" => 0 "subdocumento" => "cor" "cita" => "Actas Dermosifiliogr. 2012;103:165-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5157 "formatos" => array:3 [ "EPUB" => 50 "HTML" => 4109 "PDF" => 998 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Topical Rapamycin Solution to Treat Multiple Facial Angiofibromas in a Patient With Tuberous Sclerosis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "165" "paginaFinal" => "167" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilización de solución de rapamicina tópica para el tratamiento de múltiples angiofibromas faciales en una paciente con esclerosis tuberosa" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2073 "Ancho" => 1587 "Tamanyo" => 389316 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Clinical image of the lesions before the start of treatment. Multiple facial angiofibromas predominantly affecting the cheeks, with a prominent erythematous base.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P. Valerón-Almazán, M. Vitiello, A. Abuchar, F.A. Kerdel" "autores" => array:4 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Valerón-Almazán" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Vitiello" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Abuchar" ] 3 => array:2 [ "nombre" => "F.A." "apellidos" => "Kerdel" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731011003395" "doi" => "10.1016/j.ad.2011.02.019" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731011003395?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219012000728?idApp=UINPBA000044" "url" => "/15782190/0000010300000002/v1_201304241253/S1578219012000728/v1_201304241253/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>" "titulo" => "Frontal Fibrosing Alopecia: Dermoscopic Features" "tieneTextoCompleto" => true "saludo" => "Dear Editor:" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "167" "paginaFinal" => "169" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "H. Mireles-Rocha, L.E. Sánchez-Dueñas, M. Hernández-Torres" "autores" => array:3 [ 0 => array:3 [ "nombre" => "H." "apellidos" => "Mireles-Rocha" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "nombre" => "L.E." "apellidos" => "Sánchez-Dueñas" "email" => array:1 [ 0 => "dr_lesd@hotmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "M." "apellidos" => "Hernández-Torres" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Dermatología, Colima Col., Mexico" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto Dermatológico de Jalisco Dr. José Barba Rubio, Mexico" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Departamento de Dermatopatología, Instituto Dermatológico de Jalisco Dr. José Barba Rubio, Mexico" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Alopecia frontal fibrosante. Hallazgos dermatoscópicos" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1165 "Ancho" => 1587 "Tamanyo" => 267008 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Woman aged 51 years with a bald patch in the form of a band on the frontotemporal region. Note the receding hairline.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">First described by Kossard<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> in 1994, frontal fibrosing alopecia is a type of cicatricial alopecia that is clinically characterized by progressive and symmetrical recession of the frontotemporal hairline. It is accompanied by partial alopecia of the eyebrows in most cases<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and loss of body hair in a variable number of patients.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> It is more frequent in postmenopausal women, although there have been reports of cases in men and premenopausal women.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,4</span></a> Histopathology shows it to be a variant of lichen planopilaris, which is characterized by a reduced number of hair follicles, a perifollicular lymphocytic inflammatory infiltrate, and fibrosis.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Few published studies describe the dermoscopic features of frontal fibrosing alopecia.<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">6,7</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">We report the case of a 51-year-old woman who consulted with a 12-month history of hair loss at the frontal hairline. No other symptoms or associated diseases were present. Physical examination revealed a bald patch in the form of a band that delimited the hairline of the frontal region (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). She also had partial alopecia of the eyebrows. The remaining findings were normal. The patient had previously taken high-potency topical corticosteroids and 2% minoxidil with no signs of improvement.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Dermoscopy (Dermlite 00 multispectral) highlighted a marked reduction in the number of follicular ostia in the central area and erythema, perifollicular desquamation, and perifollicular blue-gray dots at the border of the patch (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). A biopsy specimen was taken, and histopathology revealed a marked reduction in the density of the pilosebaceous units, as well as laminar fibrosis and a perifollicular lymphocytic inflammatory infiltrate around the isthmus and infundibulum (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>). The clinical, dermoscopic, and histopathologic findings confirmed a diagnosis of frontal fibrosing alopecia.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Since it was first described in 1994, just under 200 cases of frontal fibrosing alopecia have been reported throughout the world.<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1,2,4</span></a> Although initially considered an uncommon entity, this condition is believed to be a much more common cause of cicatricial alopecia than previously thought.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> There are few published reports of dermoscopic findings in patients with this condition. Several dermoscopic findings are characteristic of frontal fibrosing alopecia, whereas others also appear in other types of cicatricial alopecia, such as discoid lupus erythematosus or lichen planopilaris. Inui et al.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> reported 3 dermoscopic findings in 4 patients with frontal fibrosing alopecia, namely, reduced follicular ostia, erythema, and perifollicular scale, which were also found in the case we report. Other dermoscopic findings also reported in patients with this condition include ramified capillaries, honeycomb-like pigment network, white patches, white dots, and vellus hair.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> In the present case, we also identified blue-gray dots around some follicles, a finding that has previously been reported in discoid lupus erythematosus, but not in frontal fibrosing alopecia.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> Although no studies have established a correlation between dermoscopic findings and histopathologic findings in cicatricial alopecia, it has been suggested that the white patches correspond to fibrosis and that they are more commonly found in long-standing bald patches.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> The blue-gray dots correspond to melanophages in the papillary dermis and the white dots to pigment incontinence<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a>; the honeycomb pattern is the result of exposure of the bald patches to sunlight.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> Erythema and hyperkeratosis are the results of inflammation in the follicle and the hyperkeratosis that develops in lichen planopilaris and frontal fibrosing alopecia.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Dermoscopic criteria are proving useful in the diagnosis of alopecia.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> In the present case, dermoscopic findings enabled us to rule out other causes of alopecia, such as alopecia areata. The correlation between clinical findings, dermoscopic findings, and histopathologic findings enabled us to establish a diagnosis of frontal fibrosing alopecia.</p><p id="par0030" class="elsevierStylePara elsevierViewall">To date, no cases of frontal fibrosing alopecia have been reported in Latin America. Although this condition has characteristic manifestations, dermoscopy provides more detailed information. The present case underlines the role of dermoscopy for evaluating cicatricial alopecia and establishing a differential diagnosis.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Please cite this article as: Mireles-Rocha H, et al. Alopecia frontal fibrosante. Hallazagos dermatoscópicos. Actas Dermosifliogr. 2012;103:167–8.</p>" ] ] "multimedia" => array:3 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1165 "Ancho" => 1587 "Tamanyo" => 267008 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Woman aged 51 years with a bald patch in the form of a band on the frontotemporal region. Note the receding hairline.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1037 "Ancho" => 1587 "Tamanyo" => 156784 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Dermoscopy (Dermlite 00 multispectral) revealed markedly reduced follicular ostia, scale, erythema, and perifollicular blue-gray dots.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1677 "Ancho" => 2087 "Tamanyo" => 634663 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Histopathology revealed a reduction in the number of hair follicles, lymphocytic inflammatory infiltrate, and laminated perifollicular fibrosis (hematoxylin–eosin, original magnification 40×).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Kossard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1994" "volumen" => "130" "paginaInicial" => "770" "paginaFinal" => "774" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8002649" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Expanding the spectrum of frontal fibrosing alopecia: a unifying concept" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A.L. Chew" 1 => "S.J. Bashir" 2 => "E.M. Wain" 3 => "D.A. Fenton" 4 => "C.M. Stefanato" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2009.09.020" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2010" "volumen" => "63" "paginaInicial" => "653" "paginaFinal" => "660" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20846567" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Frontal fibrosing alopecia: clinical presentations and prognosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "K.T. Tan" 1 => "A.G. Messenger" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2008.08861.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2009" "volumen" => "160" "paginaInicial" => "75" "paginaFinal" => "79" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18811690" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Frontal fibrosing alopecia: a clinical review of 36 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Samrao" 1 => "A.L. Chew" 2 => "V. Price" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2010.09965.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2010" "volumen" => "163" "paginaInicial" => "1296" "paginaFinal" => "1300" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20698851" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Alopecia frontal fibrosante. Valoración diagnóstica y terapéutica" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D. Moreno-Ramírez" 1 => "L. Ferrándiz" 2 => "F.M. Camacho" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2007" "volumen" => "98" "paginaInicial" => "594" "paginaFinal" => "602" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17961448" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopic findings in frontal fibrosing alopecia: report of four cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Inui" 1 => "T. Nakajima" 2 => "F. Shono" 3 => "S. Itami" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2008.03681.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2008" "volumen" => "47" "paginaInicial" => "796" "paginaFinal" => "799" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18717858" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermoscopy patterns of cicatricial alopecia resulting from discoid lupus erythematosus and lichen planopilaris" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B. Duque-Estrada" 1 => "C. Tamler" 2 => "C. Tavares-Sodré" 3 => "C. Baptista-Barcaui" 4 => "F.B. Carlos-Pereira" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "An Bras Dermatol" "fecha" => "2010" "volumen" => "85" "paginaInicial" => "179" "paginaFinal" => "183" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20520933" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Videodermoscopy in the evaluation of hair and scalp disorders" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E.K. Ross" 1 => "C. Vincenzi" 2 => "A. Tosti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2006.04.058" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2006" "volumen" => "55" "paginaInicial" => "799" "paginaFinal" => "806" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17052485" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical significance of dermoscopy in alopecia areata: analysis of 300 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Inui" 1 => "T. Nakajima" 2 => "K. Nakagawa" 3 => "S. Itami" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-4632.2008.03692.x" "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "2008" "volumen" => "47" "paginaInicial" => "688" "paginaFinal" => "693" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18613874" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010300000002/v1_201304241253/S157821901200073X/v1_201304241253/en/main.assets" "Apartado" => array:4 [ "identificador" => "6169" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Cases and Research Letters" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010300000002/v1_201304241253/S157821901200073X/v1_201304241253/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821901200073X?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 15 | 11 | 26 |
| 2024 October | 103 | 33 | 136 |
| 2024 September | 123 | 23 | 146 |
| 2024 August | 151 | 49 | 200 |
| 2024 July | 132 | 32 | 164 |
| 2024 June | 125 | 43 | 168 |
| 2024 May | 127 | 30 | 157 |
| 2024 April | 119 | 39 | 158 |
| 2024 March | 114 | 31 | 145 |
| 2024 February | 113 | 52 | 165 |
| 2024 January | 107 | 54 | 161 |
| 2023 December | 96 | 19 | 115 |
| 2023 November | 138 | 26 | 164 |
| 2023 October | 114 | 32 | 146 |
| 2023 September | 132 | 40 | 172 |
| 2023 August | 92 | 23 | 115 |
| 2023 July | 135 | 53 | 188 |
| 2023 June | 107 | 48 | 155 |
| 2023 May | 90 | 45 | 135 |
| 2023 April | 96 | 44 | 140 |
| 2023 March | 107 | 62 | 169 |
| 2023 February | 85 | 37 | 122 |
| 2023 January | 71 | 46 | 117 |
| 2022 December | 105 | 64 | 169 |
| 2022 November | 62 | 32 | 94 |
| 2022 October | 55 | 28 | 83 |
| 2022 September | 60 | 52 | 112 |
| 2022 August | 56 | 40 | 96 |
| 2022 July | 54 | 38 | 92 |
| 2022 June | 59 | 37 | 96 |
| 2022 May | 140 | 32 | 172 |
| 2022 April | 100 | 42 | 142 |
| 2022 March | 89 | 62 | 151 |
| 2022 February | 75 | 35 | 110 |
| 2022 January | 84 | 42 | 126 |
| 2021 December | 77 | 51 | 128 |
| 2021 November | 84 | 42 | 126 |
| 2021 October | 60 | 55 | 115 |
| 2021 September | 73 | 49 | 122 |
| 2021 August | 54 | 42 | 96 |
| 2021 July | 77 | 35 | 112 |
| 2021 June | 78 | 46 | 124 |
| 2021 May | 94 | 37 | 131 |
| 2021 April | 153 | 87 | 240 |
| 2021 March | 245 | 32 | 277 |
| 2021 February | 108 | 31 | 139 |
| 2021 January | 57 | 22 | 79 |
| 2020 December | 65 | 25 | 90 |
| 2020 November | 70 | 19 | 89 |
| 2020 October | 49 | 8 | 57 |
| 2020 September | 47 | 15 | 62 |
| 2020 August | 62 | 18 | 80 |
| 2020 July | 144 | 20 | 164 |
| 2020 June | 100 | 27 | 127 |
| 2020 May | 44 | 22 | 66 |
| 2020 April | 36 | 28 | 64 |
| 2020 March | 32 | 27 | 59 |
| 2020 February | 9 | 11 | 20 |
| 2020 January | 0 | 8 | 8 |
| 2019 December | 0 | 14 | 14 |
| 2019 November | 0 | 11 | 11 |
| 2019 October | 0 | 8 | 8 |
| 2019 September | 0 | 10 | 10 |
| 2019 August | 0 | 6 | 6 |
| 2019 July | 0 | 11 | 11 |
| 2019 June | 1 | 22 | 23 |
| 2019 May | 0 | 13 | 13 |
| 2019 April | 2 | 20 | 22 |
| 2019 March | 0 | 5 | 5 |
| 2019 February | 0 | 3 | 3 |
| 2019 January | 1 | 2 | 3 |
| 2018 December | 0 | 7 | 7 |
| 2018 November | 2 | 0 | 2 |
| 2018 October | 3 | 0 | 3 |
| 2018 September | 2 | 2 | 4 |
| 2018 July | 0 | 1 | 1 |
| 2018 April | 0 | 5 | 5 |
| 2018 March | 3 | 13 | 16 |
| 2018 February | 119 | 11 | 130 |
| 2018 January | 175 | 11 | 186 |
| 2017 December | 133 | 7 | 140 |
| 2017 November | 106 | 17 | 123 |
| 2017 October | 116 | 14 | 130 |
| 2017 September | 116 | 29 | 145 |
| 2017 August | 172 | 15 | 187 |
| 2017 July | 131 | 25 | 156 |
| 2017 June | 149 | 24 | 173 |
| 2017 May | 126 | 15 | 141 |
| 2017 April | 105 | 9 | 114 |
| 2017 March | 90 | 28 | 118 |
| 2017 February | 85 | 24 | 109 |
| 2017 January | 100 | 23 | 123 |
| 2016 December | 118 | 16 | 134 |
| 2016 November | 146 | 27 | 173 |
| 2016 October | 185 | 17 | 202 |
| 2016 September | 245 | 14 | 259 |
| 2016 August | 218 | 26 | 244 |
| 2016 July | 99 | 10 | 109 |
| 2016 June | 12 | 13 | 25 |
| 2016 May | 9 | 12 | 21 |
| 2016 April | 14 | 1 | 15 |
| 2016 March | 5 | 16 | 21 |
| 2016 February | 7 | 2 | 9 |
| 2016 January | 14 | 20 | 34 |
| 2015 December | 11 | 1 | 12 |
| 2015 November | 40 | 16 | 56 |
| 2015 October | 73 | 2 | 75 |
| 2015 September | 30 | 8 | 38 |
| 2015 August | 16 | 7 | 23 |
| 2015 July | 191 | 11 | 202 |
| 2015 June | 134 | 16 | 150 |
| 2015 May | 125 | 24 | 149 |
| 2015 April | 159 | 15 | 174 |
| 2015 March | 173 | 15 | 188 |
| 2015 February | 155 | 13 | 168 |
| 2015 January | 110 | 20 | 130 |
| 2014 December | 99 | 13 | 112 |
| 2014 November | 113 | 14 | 127 |
| 2014 October | 94 | 13 | 107 |
| 2014 September | 129 | 14 | 143 |
| 2014 August | 78 | 15 | 93 |
| 2014 July | 105 | 19 | 124 |
| 2014 June | 112 | 16 | 128 |
| 2014 May | 146 | 13 | 159 |
| 2014 April | 113 | 12 | 125 |
| 2014 March | 127 | 25 | 152 |
| 2014 February | 33 | 15 | 48 |
| 2014 January | 46 | 6 | 52 |
| 2013 December | 67 | 13 | 80 |
| 2013 November | 50 | 7 | 57 |
| 2013 October | 31 | 13 | 44 |
| 2013 September | 38 | 11 | 49 |
| 2013 August | 62 | 13 | 75 |
| 2013 July | 45 | 8 | 53 |
| 2013 June | 22 | 12 | 34 |
| 2013 May | 19 | 17 | 36 |
| 2013 April | 16 | 6 | 22 |
| 2013 March | 17 | 20 | 37 |
| 2013 February | 50 | 14 | 64 |
| 2013 January | 100 | 10 | 110 |
| 2012 December | 50 | 6 | 56 |
| 2012 November | 1 | 4 | 5 |
| 2012 October | 3 | 7 | 10 |
Show all
