Original Article
Feasibility and Reliability of the Spanish Version of the Leeds Revised Acne Grading Scale
Factibilidad y fiabilidad de la versión española de la escala revisada de gravedad de Leeds (LRAG) para pacientes con acné
A. Guerra-Tapiaa,
, L. Puig-Sanzb, J. Conejo Mirc, J. Toribio-Pérezd, C. Iglesiase, I. Zsoltf
Corresponding author
a Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, Spain
b Servicio de Dermatología, Hospital de Sant Pau, Barcelona, Spain
c Servicio de Dermatología, Hospital Universitario Vírgen del Rocío, Sevilla, Spain
d Servicio de Dermatología, Hospital Clínico Universitario, Santiago de Compostela, Spain
e Departamento Médico, Salutis-Research SL, Barcelona, Spain
f Departamento Médico, Grupo Ferrer, Barcelona, Spain
Read
6765
Timeswas read the article
3377
Total PDF
3388
Total HTML
Share statistics
array:23 [ "pii" => "S1578219010707162" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70716-2" "estado" => "S300" "fechaPublicacion" => "2010-11-01" "aid" => "70716" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2010" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:778-84" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2380 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 1374 "PDF" => 968 ] ] "itemSiguiente" => array:18 [ "pii" => "S1578219010707174" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70717-4" "estado" => "S300" "fechaPublicacion" => "2010-11-01" "aid" => "70717" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:785-91" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1833 "formatos" => array:3 [ "EPUB" => 36 "HTML" => 1171 "PDF" => 626 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Plaque-Phase Mycosis Fungoides Treated with Photodynamic Therapy: Results from 12 Patients" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "785" "paginaFinal" => "791" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Micosis fungoide en fase de placas tratada con terapia fotodinámica: resultados en 12 pacientes" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Fernández-Guarino, A. Harto, B. Pérez-García, C. Montull, E. De Las Heras, P. Jaén" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Fernández-Guarino" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Harto" ] 2 => array:2 [ "nombre" => "B." "apellidos" => "Pérez-García" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Montull" ] 4 => array:2 [ "nombre" => "E." "apellidos" => "De Las Heras" ] 5 => array:2 [ "nombre" => "P." "apellidos" => "Jaén" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707174?idApp=UINPBA000044" "url" => "/15782190/0000010100000009/v1_201304241531/S1578219010707174/v1_201304241531/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219010707150" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70715-0" "estado" => "S300" "fechaPublicacion" => "2010-11-01" "aid" => "70715" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:771-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 1981 "formatos" => array:3 [ "EPUB" => 30 "HTML" => 1301 "PDF" => 650 ] ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "Epidemiology of Pediatric Dermatologic Surgery: A Retrospective Study of 996 Children" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "771" "paginaFinal" => "777" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Epidemiología de la cirugía dermatológica pediátrica. Un estudio retrospectivo de 996 niños" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "V. López, J.M. Martín, C. Monteagudo, E. Jordá" "autores" => array:4 [ 0 => array:2 [ "nombre" => "V." "apellidos" => "López" ] 1 => array:2 [ "nombre" => "J.M." "apellidos" => "Martín" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Monteagudo" ] 3 => array:2 [ "nombre" => "E." "apellidos" => "Jordá" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707150?idApp=UINPBA000044" "url" => "/15782190/0000010100000009/v1_201304241531/S1578219010707150/v1_201304241531/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>" "titulo" => "Feasibility and Reliability of the Spanish Version of the Leeds Revised Acne Grading Scale" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "778" "paginaFinal" => "784" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Guerra-Tapia, L. Puig-Sanz, J. Conejo Mir, J. Toribio-Pérez, C. Iglesias, I. Zsolt" "autores" => array:6 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Guerra-Tapia" "email" => array:1 [ 0 => "aguerra.hdoc@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "L." "apellidos" => "Puig-Sanz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J." "apellidos" => "Conejo Mir" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Toribio-Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] 4 => array:3 [ "nombre" => "C." "apellidos" => "Iglesias" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff0025" ] ] ] 5 => array:3 [ "nombre" => "I." "apellidos" => "Zsolt" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "aff0030" ] ] ] ] "afiliaciones" => array:6 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital de Sant Pau, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Vírgen del Rocío, Sevilla, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario, Santiago de Compostela, Spain" "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] 4 => array:3 [ "entidad" => "Departamento Médico, Salutis-Research SL, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff0025" ] 5 => array:3 [ "entidad" => "Departamento Médico, Grupo Ferrer, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">f</span>" "identificador" => "aff0030" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Factibilidad y fiabilidad de la versión española de la escala revisada de gravedad de Leeds (LRAG) para pacientes con acné" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-07-28" "fechaAceptado" => "2010-03-23" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84816" "palabras" => array:4 [ 0 => "Acne vulgaris" 1 => "Diagnosis of acne" 2 => "Acne classification" 3 => "Validation of scales" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84817" "palabras" => array:4 [ 0 => "Acné vulgar" 1 => "Diagnóstico de acné" 2 => "Clasificación de acné" 3 => "Validación de escala" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Background</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Although there are more than 25 acne grading systems, there is no consensus on which is most appropriate. Unification of the classifications is recommended in order to facilitate therapeutic decisions.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To assess the feasibility and reliability of the Spanish version of the Leeds revised acne grading (LRAG) scale in patients with acne vulgaris in Spain.</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We conducted a prospective, multicenter, observational study in Spain, including patients with acne affecting at least 1 of 3 regions: face, back, or chest. Patients were assessed using the LRAG scale and lesion counting. Changes in the scores were determined at 4-6 weeks, and were correlated with the lesion count. Physicians were asked 4 questions regarding difficulty using the scale and the time employed.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">A total of 259 sites of acne were assessed in 239 patients at 57 centers. The majority of physicians (89.5%) stated that the LRAG scale was not difficult to use. The mean administration time was 3.12 min. Cross-sectional validity (<span class="elsevierStyleItalic">P</span><.012 for the face, <span class="elsevierStyleItalic">P</span><.001 for the back and chest), longitudinal validity (<span class="elsevierStyleItalic">P</span><.0001 for the face, back, and chest), and intraobserver and interobserver reliability (Cronbach α >0.8) were significant for inflammatory lesions in all regions. Sensitivity to change was demonstrated for lesions in all regions, based on the correlation between the difference in severity and the number of lesions recorded by the LRAG, and the difference in the lesion count between baseline and follow-up.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The Spanish version of the LRAG scale is a practical and reliable tool and is sensitive to change. It is a valid tool for the objective assessment of the severity of acne.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se describen más de 25 métodos para valorar la gravedad del acné y, aunque no hay consenso sobre una escala, se recomienda unificar su clasificación para facilitar las decisiones terapéuticas.</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Validar la factibilidad y fiabilidad de la escala revisada de gravedad de Leeds (LRAG) en pacientes con acné vulgar en España.</p> <span class="elsevierStyleSectionTitle">Material y métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional prospectivo multicéntrico español que evaluó mediante la escala LRAG y el recuento de lesiones a pacientes con acné en al menos una de tres localizaciones (cara, pecho o espalda). Se analizaron los cambios en la puntuación a las 5 ± 1 semanas y se correlacionaron con el recuento de lesiones. El clínico respondió 4 preguntas sobre dificultad y tiempo de uso de la escala.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Fueron evaluadas 259 localizaciones de acné en 239 pacientes y en 57 centros asistenciales. El 89,5% [IC: 85-92,9%] de los médicos opinaron que la escala se usó sin dificultad y su tiempo medio de administración fue de 3,12 min. La validez transversal (p < 0,012 facial, p < 0,001 espalda y pecho), validez longitudinal (p < 0,0001) y fiabilidad intra e interobservador (alfa de Cronbach ≥ 0,8) de la escala fue significativa en todas las localizaciones. En relación a sensibilidad al cambio de la escala, las lesiones observadas en todas las localizaciones en el seguimiento dependen de la diferencia de gravedad registrada por la escala LRAG y el recuento de lesiones basales.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La versión española de la escala LRAG es factible, fiable, sensible y constituye una herramienta válida para objetivar clínicamente la gravedad del acné.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:22 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of acne in women over 25 years of age" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R. Rivera" 1 => "A. Guerra" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2009" "volumen" => "100" "paginaInicial" => "33" "paginaFinal" => "37" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20096195" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnosis and treatment of acne" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "S. Feldman" 1 => "R.E. Careccia" 2 => "K.L. Barham" 3 => "J. Hancox" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am Fam Physician" "fecha" => "2004" "volumen" => "69" "paginaInicial" => "2123" "paginaFinal" => "2130" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15152959" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An acne grading method using photographic standards" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.H. Cook" 1 => "R.L. Centner" 2 => "S.E. Michaels" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1979" "volumen" => "115" "paginaInicial" => "571" "paginaFinal" => "575" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/156006" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acne therapy: a methodologic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.P. Lehmann" 1 => "K.A. Robinson" 2 => "J.S. Andrews" 3 => "V. Holloway" 4 => "S.N. Goodman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "231" "paginaFinal" => "240" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12140469" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Establishment of grading criteria for acne severity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "N. Hayashi" 1 => "H. Akamatsu" 2 => "M. Kawashima" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1346-8138.2007.00403.x-i1" "Revista" => array:6 [ "tituloSerie" => "J Dermatol" "fecha" => "2008" "volumen" => "35" "paginaInicial" => "255" "paginaFinal" => "260" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18477223" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Outcome measures in acne vulgaris: systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "H. Barratt" 1 => "F. Hamilton" 2 => "J. Car" 3 => "C. Lyons" 4 => "A. Layton" 5 => "A. Majeed" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2008.08819.x" "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "2009" "volumen" => "160" "paginaInicial" => "132" "paginaFinal" => "136" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19067711" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Guidelines of care for acne vulgaris management" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.S. Strauss" 1 => "D.P. Krowchuk" 2 => "J.J. Leyden" 3 => "A.W. Lucky" 4 => "A.R. Shalita" 5 => "E.C. Siegfried" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2006.08.048" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2007" "volumen" => "56" "paginaInicial" => "651" "paginaFinal" => "663" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17276540" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The assessment of acne vulgaris—the Leeds technique" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B.M. Burke" 1 => "W.J. Cunliffe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1984" "volumen" => "111" "paginaInicial" => "83" "paginaFinal" => "92" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6331492" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510712001381" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The Leeds revised acne grading system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S.C.L.J. O’Brien" 1 => "W.J. Cunliffe" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Dermatolog Treat" "fecha" => "1998" "volumen" => "9" "paginaInicial" => "215" "paginaFinal" => "220" ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "ECLA grading: a system of acne classification for every day dermatological practice" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "B. Dreno" 1 => "I. Bodokh" 2 => "M. Chivot" 3 => "F. Daniel" 4 => "P. Humbert" 5 => "F. Poli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Dermatol Venereol" "fecha" => "1999" "volumen" => "126" "paginaInicial" => "136" "paginaFinal" => "141" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10352828" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Remote assessment of acne: the use of acne grading tools to evaluate digital skin images" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H. Bergman" 1 => "K.Y. Tsai" 2 => "S.J. Seo" 3 => "J.C. Kvedar" 4 => "A.J. Watson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/tmj.2008.0128" "Revista" => array:6 [ "tituloSerie" => "Telemed J E Health" "fecha" => "2009" "volumen" => "15" "paginaInicial" => "426" "paginaFinal" => "430" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19548822" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Current Measures for the Evaluation of Acne Severity" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.K. Tan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Expert Rev Dermatol" "fecha" => "2008" "volumen" => "3" "paginaInicial" => "595" "paginaFinal" => "603" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development and validation of a comprehensive acne severity scale" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "J.K. Tan" 1 => "J. Tang" 2 => "K. Fung" 3 => "A.K. Gupta" 4 => "D.R. Thomas" 5 => "S. Sapra" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Cutan Med Surg" "fecha" => "2007" "volumen" => "11" "paginaInicial" => "211" "paginaFinal" => "216" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18042334" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mechanism-based treatment of acne vulgaris: the value of combination therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G. Webster" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Drugs Dermatol" "fecha" => "2005" "volumen" => "4" "paginaInicial" => "281" "paginaFinal" => "288" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15898282" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Office application of a new acne grading system" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.G. Wilson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cutis" "fecha" => "1980" "volumen" => "25" "paginaInicial" => "62" "paginaFinal" => "64" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6444378" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The assessment of acne: an evaluation of grading and lesion counting in the measurement of acne" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.A. Witkowski" 1 => "L.C. Parish" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.clindermatol.2004.03.008" "Revista" => array:6 [ "tituloSerie" => "Clin Dermatol" "fecha" => "2004" "volumen" => "22" "paginaInicial" => "394" "paginaFinal" => "397" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15556725" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fluorescence photography in the evaluation of acne" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L.C. Lucchina" 1 => "N. Kollias" 2 => "R. Gillies" 3 => "S.B. Phillips" 4 => "J.A. Muccini" 5 => "M.J. Stiller" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0190-9622(96)90497-1" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1996" "volumen" => "35" "paginaInicial" => "58" "paginaFinal" => "63" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8682965" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A multirater validation study to assess the reliability of acne lesion counting" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A.W. Lucky" 1 => "B.L. Barber" 2 => "C.J. Girman" 3 => "J. Williams" 4 => "J. Ratterman" 5 => "J. Waldstreicher" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "1996" "volumen" => "35" "paginaInicial" => "559" "paginaFinal" => "565" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8859284" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New photographic techniques for clinical evaluation of acne" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Rizova" 1 => "A. Kligman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2001" "volumen" => "15" "numero" => "Suppl 3" "paginaInicial" => "13" "paginaFinal" => "18" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11843228" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Desarrollo de un cuestionario de evaluación de la satisfacción con el tratamiento en paciente con acné" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "A. Alomar" 1 => "A. Guerra" 2 => "N. Perulero" 3 => "X. Badía" 4 => "L. Canals" 5 => "C. Álvarez" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2004" "volumen" => "95" "paginaInicial" => "491" "paginaFinal" => "495" ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Adaptación transcultural al Español del cuestionario Dermatology Life Quality Index (DLQI): el Índice de Calidad de Vida en Dermatología" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. De Tiedra" 1 => "J. Mercadal" 2 => "X. Badía" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifilogr" "fecha" => "1998" "volumen" => "89" "paginaInicial" => "692" "paginaFinal" => "700" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A method to select an instrument for measurement of HR-QOL for cross-cultural adaptation applied to dermatology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. De Tiedra" 1 => "J. Mercadal" 2 => "X. Badía" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pharmacoeconomics" "fecha" => "1998" "volumen" => "14" "paginaInicial" => "405" "paginaFinal" => "422" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10344908" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010100000009/v1_201304241531/S1578219010707162/v1_201304241531/en/main.assets" "Apartado" => array:4 [ "identificador" => "6256" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original article" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010100000009/v1_201304241531/S1578219010707162/v1_201304241531/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010707162?idApp=UINPBA000044" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 7 | 9 | 16 |
| 2024 October | 70 | 47 | 117 |
| 2024 September | 54 | 40 | 94 |
| 2024 August | 91 | 65 | 156 |
| 2024 July | 59 | 43 | 102 |
| 2024 June | 70 | 27 | 97 |
| 2024 May | 54 | 46 | 100 |
| 2024 April | 57 | 41 | 98 |
| 2024 March | 53 | 38 | 91 |
| 2024 February | 49 | 33 | 82 |
| 2024 January | 45 | 41 | 86 |
| 2023 December | 56 | 40 | 96 |
| 2023 November | 51 | 29 | 80 |
| 2023 October | 48 | 39 | 87 |
| 2023 September | 43 | 46 | 89 |
| 2023 August | 42 | 32 | 74 |
| 2023 July | 34 | 68 | 102 |
| 2023 June | 55 | 46 | 101 |
| 2023 May | 39 | 51 | 90 |
| 2023 April | 26 | 42 | 68 |
| 2023 March | 15 | 36 | 51 |
| 2023 February | 22 | 27 | 49 |
| 2023 January | 31 | 42 | 73 |
| 2022 December | 24 | 50 | 74 |
| 2022 November | 18 | 44 | 62 |
| 2022 October | 14 | 33 | 47 |
| 2022 September | 17 | 58 | 75 |
| 2022 August | 16 | 43 | 59 |
| 2022 July | 18 | 42 | 60 |
| 2022 June | 13 | 54 | 67 |
| 2022 May | 22 | 84 | 106 |
| 2022 April | 35 | 59 | 94 |
| 2022 March | 35 | 53 | 88 |
| 2022 February | 28 | 56 | 84 |
| 2022 January | 29 | 62 | 91 |
| 2021 December | 27 | 44 | 71 |
| 2021 November | 40 | 59 | 99 |
| 2021 October | 31 | 51 | 82 |
| 2021 September | 27 | 61 | 88 |
| 2021 August | 19 | 58 | 77 |
| 2021 July | 16 | 49 | 65 |
| 2021 June | 36 | 36 | 72 |
| 2021 May | 25 | 38 | 63 |
| 2021 April | 56 | 77 | 133 |
| 2021 March | 40 | 19 | 59 |
| 2021 February | 67 | 34 | 101 |
| 2021 January | 23 | 24 | 47 |
| 2020 December | 32 | 23 | 55 |
| 2020 November | 25 | 31 | 56 |
| 2020 October | 18 | 34 | 52 |
| 2020 September | 14 | 14 | 28 |
| 2020 August | 20 | 39 | 59 |
| 2020 July | 28 | 17 | 45 |
| 2020 June | 34 | 39 | 73 |
| 2020 May | 25 | 30 | 55 |
| 2020 April | 27 | 29 | 56 |
| 2020 March | 40 | 31 | 71 |
| 2020 February | 4 | 10 | 14 |
| 2020 January | 0 | 14 | 14 |
| 2019 December | 0 | 24 | 24 |
| 2019 November | 0 | 3 | 3 |
| 2019 October | 0 | 13 | 13 |
| 2019 September | 0 | 7 | 7 |
| 2019 August | 0 | 5 | 5 |
| 2019 July | 0 | 9 | 9 |
| 2019 June | 0 | 11 | 11 |
| 2019 May | 1 | 41 | 42 |
| 2019 April | 0 | 4 | 4 |
| 2019 March | 0 | 13 | 13 |
| 2019 February | 0 | 4 | 4 |
| 2018 December | 0 | 2 | 2 |
| 2018 October | 1 | 3 | 4 |
| 2018 September | 2 | 7 | 9 |
| 2018 August | 0 | 2 | 2 |
| 2018 June | 0 | 5 | 5 |
| 2018 May | 0 | 3 | 3 |
| 2018 April | 0 | 1 | 1 |
| 2018 March | 0 | 1 | 1 |
| 2018 February | 9 | 3 | 12 |
| 2018 January | 10 | 6 | 16 |
| 2017 December | 23 | 12 | 35 |
| 2017 November | 14 | 2 | 16 |
| 2017 October | 11 | 3 | 14 |
| 2017 September | 11 | 20 | 31 |
| 2017 August | 12 | 4 | 16 |
| 2017 July | 19 | 7 | 26 |
| 2017 June | 17 | 14 | 31 |
| 2017 May | 11 | 10 | 21 |
| 2017 April | 12 | 10 | 22 |
| 2017 March | 10 | 42 | 52 |
| 2017 February | 13 | 6 | 19 |
| 2017 January | 11 | 14 | 25 |
| 2016 December | 36 | 7 | 43 |
| 2016 November | 31 | 9 | 40 |
| 2016 October | 28 | 19 | 47 |
| 2016 September | 40 | 19 | 59 |
| 2016 August | 30 | 14 | 44 |
| 2016 July | 24 | 3 | 27 |
| 2016 June | 10 | 15 | 25 |
| 2016 May | 6 | 13 | 19 |
| 2016 April | 7 | 19 | 26 |
| 2016 March | 6 | 6 | 12 |
| 2016 February | 4 | 2 | 6 |
| 2016 January | 8 | 2 | 10 |
| 2015 December | 8 | 1 | 9 |
| 2015 November | 11 | 1 | 12 |
| 2015 October | 9 | 6 | 15 |
| 2015 September | 8 | 3 | 11 |
| 2015 August | 15 | 3 | 18 |
| 2015 July | 34 | 11 | 45 |
| 2015 June | 31 | 7 | 38 |
| 2015 May | 55 | 14 | 69 |
| 2015 April | 35 | 8 | 43 |
| 2015 March | 39 | 12 | 51 |
| 2015 February | 19 | 7 | 26 |
| 2015 January | 17 | 9 | 26 |
| 2014 December | 31 | 6 | 37 |
| 2014 November | 17 | 8 | 25 |
| 2014 October | 27 | 12 | 39 |
| 2014 September | 31 | 9 | 40 |
| 2014 August | 20 | 11 | 31 |
| 2014 July | 32 | 15 | 47 |
| 2014 June | 34 | 14 | 48 |
| 2014 May | 39 | 15 | 54 |
| 2014 April | 37 | 7 | 44 |
| 2014 March | 45 | 21 | 66 |
| 2014 February | 31 | 13 | 44 |
| 2014 January | 31 | 14 | 45 |
| 2013 December | 26 | 11 | 37 |
| 2013 November | 35 | 24 | 59 |
| 2013 October | 32 | 21 | 53 |
| 2013 September | 26 | 21 | 47 |
| 2013 August | 21 | 19 | 40 |
| 2013 July | 44 | 30 | 74 |
| 2013 June | 25 | 37 | 62 |
| 2013 May | 28 | 37 | 65 |
| 2013 April | 27 | 40 | 67 |
| 2013 March | 24 | 30 | 54 |
| 2013 February | 11 | 13 | 24 |
| 2013 January | 2 | 1 | 3 |
Show all
