Case Report
Intralymphatic Histiocytosis and Cancer of the Colon
Histiocitosis intralinfática y neoplasia de colon
B. Echeverría-García, R. Botella-Estrada
, C. Requena, C. Guillén
Corresponding author
Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, Spain
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Arias-Santiago, M.T. Gutiérrez-Salmerón, L. Castellote-Caballero, A. Buendía-Eisman, R. Naranjo-Sintes" "autores" => array:5 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Arias-Santiago" ] 1 => array:2 [ "nombre" => "M.T." "apellidos" => "Gutiérrez-Salmerón" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Castellote-Caballero" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Buendía-Eisman" ] 4 => array:2 [ "nombre" => "R." 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"apellidos" => "Botella-Estrada" "email" => array:1 [ 0 => "rbotellaes@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Requena" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Guillén" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Instituto Valenciano de Oncología, Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Histiocitosis intralinfática y neoplasia de colon" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-11-17" "fechaAceptado" => "2009-11-25" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84705" "palabras" => array:4 [ 0 => "Histiocytosis" 1 => "Lymph vessels" 2 => "Reactive angioendotheliomatosis" 3 => "Intravascular lymphoma" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84704" "palabras" => array:4 [ 0 => "Histiocitosis" 1 => "Vasos linfáticos" 2 => "Angioendoteliomatosis reactiva" 3 => "Linfoma intravascular" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Intralymphatic histiocytosis is a condition with nonspecific clinical features but with characteristic histopathological and immunohistochemical findings. It presents as a poorly demarcated erythematous plaque or a lesion similar to livedo reticularis, usually located on the limbs. Histologically, dilated vessels containing mononuclear cells are observed in the reticular dermis.</p><p class="elsevierStyleSimplePara elsevierViewall">In the past, the majority of these cases were thought to be cases of reactive angioendotheliomatosis or intravascular lymphoma, but the development of more specific immunohistochemical markers showed that these were dilated lymph vessels containing histiocytes, and so were considered as a separate condition.</p><p class="elsevierStyleSimplePara elsevierViewall">We present the case of a man with a past history of left axillary lymphadenectomy for lymphatic tuberculosis, leukocytoclastic vasculitis, and cancer of the colon. The patient developed an erythematous plaque in the left pectoral region. Histology and immunohistochemical stains of the lesion revealed histiocytes within dilated lymph vessels in the reticular dermis, but no neoplastic cells.</p><p class="elsevierStyleSimplePara elsevierViewall">We present a new case of intralymphatic histiocytosis in a patient with autoimmune and neoplastic diseases.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La histiocitosis intralinfática es una entidad de clínica inespecífica, pero con una histología y una inmunohistoquímica características. Se manifiesta como una placa eritematosa mal delimitada o una lesión livedoide que normalmente afecta a las extremidades. Histológicamente muestra vasos dilatados en la dermis reticular ocupados por células mononucleares.</p><p class="elsevierStyleSimplePara elsevierViewall">Los casos descritos anteriormente se diagnosticaron de angioendoteliomatosis reactiva y de linfoma intravascular, pero el desarrollo de marcadores inmunohistoquímicos más específicos demostró que eran vasos linfáticos ocupados por histiocitos y se caracterizaron, por tanto, como una entidad propia y diferenciada.</p><p class="elsevierStyleSimplePara elsevierViewall">Se presenta el caso de un varón con antecedentes de linfadenectomía axilar izquierda por una tuberculosis ganglionar, una vasculitis leucocitoclástica y una neoplasia de colon, que desarrolló una placa eritematosa en la región pectoral izquierda. En la histología y las tinciones inmunohistoquímicas se observaron histiocitos en el interior de los vasos linfáticos dilatados en la dermis reticular sin células neoplásicas.</p><p class="elsevierStyleSimplePara elsevierViewall">Se presenta un nuevo caso de histiocitosis intralinfática en un paciente con enfermedad autoinmunitaria y neoplásica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:11 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intralymphatic histiocytosis. A clinicopathologic study of 16 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Requena" 1 => "L. El-Shabrawi-Caelen" 2 => "S.N. Walsh" 3 => "S. Segura" 4 => "M. 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| 2017 October | 8 | 3 | 11 |
| 2017 September | 14 | 4 | 18 |
| 2017 August | 17 | 6 | 23 |
| 2017 July | 8 | 4 | 12 |
| 2017 June | 13 | 8 | 21 |
| 2017 May | 16 | 4 | 20 |
| 2017 April | 9 | 7 | 16 |
| 2017 March | 9 | 3 | 12 |
| 2017 February | 12 | 6 | 18 |
| 2017 January | 9 | 3 | 12 |
| 2016 December | 23 | 9 | 32 |
| 2016 November | 19 | 14 | 33 |
| 2016 October | 23 | 5 | 28 |
| 2016 September | 30 | 12 | 42 |
| 2016 August | 26 | 7 | 33 |
| 2016 July | 20 | 6 | 26 |
| 2016 June | 7 | 2 | 9 |
| 2016 May | 6 | 3 | 9 |
| 2016 April | 4 | 5 | 9 |
| 2016 March | 4 | 7 | 11 |
| 2016 February | 7 | 9 | 16 |
| 2016 January | 8 | 7 | 15 |
| 2015 December | 11 | 2 | 13 |
| 2015 November | 10 | 8 | 18 |
| 2015 October | 6 | 10 | 16 |
| 2015 September | 9 | 5 | 14 |
| 2015 August | 7 | 1 | 8 |
| 2015 July | 21 | 4 | 25 |
| 2015 June | 48 | 7 | 55 |
| 2015 May | 76 | 18 | 94 |
| 2015 April | 38 | 5 | 43 |
| 2015 March | 40 | 4 | 44 |
| 2015 February | 33 | 4 | 37 |
| 2015 January | 20 | 9 | 29 |
| 2014 December | 37 | 5 | 42 |
| 2014 November | 21 | 5 | 26 |
| 2014 October | 35 | 13 | 48 |
| 2014 September | 34 | 7 | 41 |
| 2014 August | 31 | 10 | 41 |
| 2014 July | 40 | 15 | 55 |
| 2014 June | 41 | 12 | 53 |
| 2014 May | 54 | 12 | 66 |
| 2014 April | 41 | 15 | 56 |
| 2014 March | 42 | 14 | 56 |
| 2014 February | 26 | 15 | 41 |
| 2014 January | 38 | 20 | 58 |
| 2013 December | 35 | 18 | 53 |
| 2013 November | 37 | 28 | 65 |
| 2013 October | 31 | 18 | 49 |
| 2013 September | 35 | 26 | 61 |
| 2013 August | 31 | 36 | 67 |
| 2013 July | 38 | 21 | 59 |
| 2013 June | 19 | 14 | 33 |
| 2013 May | 18 | 14 | 32 |
| 2013 April | 21 | 21 | 42 |
| 2013 March | 32 | 20 | 52 |
| 2013 February | 15 | 14 | 29 |
Show all
