Novelties in Dermatology
Contact Dermatitis Due to Dimethyl Fumarate
Dermatitis de contacto por dimetilfumarato
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Requena" "autores" => array:2 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Requena" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Requena" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010706181?idApp=UINPBA000044" "url" => "/15782190/0000010100000003/v1_201304241518/S1578219010706181/v1_201304241518/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Novelties in Dermatology</span>" "titulo" => "Contact Dermatitis Due to Dimethyl Fumarate" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "217" "paginaFinal" => "222" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.F. Silvestre, P. Mercader, A.M. Giménez-Arnau" "autores" => array:3 [ 0 => array:4 [ "nombre" => "J.F." "apellidos" => "Silvestre" "email" => array:1 [ 0 => "silvestre_jfr@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "P." "apellidos" => "Mercader" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "A.M." "apellidos" => "Giménez-Arnau" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Sección de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Sección de Dermatología, Hospital General Universitario Morales Meseguer, Murcia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital del Mar (IMAS), Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff3" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Dermatitis de contacto por dimetilfumarato" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-06-09" "fechaAceptado" => "2009-11-20" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84710" "palabras" => array:6 [ 0 => "Dimethyl fumarate" 1 => "Contact dermatitis" 2 => "Contact urticaria" 3 => "Patch test" 4 => "Shoe" 5 => "Sofa" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84711" "palabras" => array:6 [ 0 => "Dimetilfumarato" 1 => "Dermatitis de contacto" 2 => "Urticaria de contacto" 3 => "Pruebas epicutáneas" 4 => "Calzado" 5 => "Sofá" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Dimethyl fumarate is a fumaric acid ester. It has been used for some years to treat psoriasis and also as a preservative in desiccant sachets in the transport of furniture and footwear. Its irritant properties and sensitizing potential in contact with the skin were recently highlighted when it was implicated as the causative agent in 2 epidemics of severe acute eczema: sofa dermatitis in northern Europe and shoe dermatitis in Spain. The present article aims to guide dermatologists in the diagnosis and management of patients allergic to dimethyl fumarate. We review the clinical manifestations, results of patch tests, possible cross-reactions, and sources of exposure to dimethyl fumarate responsible for these skin reactions.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El dimetilfumarato es un éster del ácido fumárico que se utiliza desde hace años para el tratamiento de la psoriasis; además se emplea como conservante en bolsitas antihumedad para garantizar el transporte de muebles y calzado. Su capacidad irritante en contacto con la piel y su alta capacidad sensibilizante han quedado demostradas recientemente tras haber sido implicado como agente causal en dos epidemias de eccema agudo grave: por un lado, la «dermatitis del sofá» en el norte de Europa, y por otro lado, una epidemia de dermatitis por calzado en España. El presente artículo pretende orientar a los dermatólogos en el diagnóstico y tratamiento de los pacientes alérgicos al dimetilfumarato. Repasamos las manifestaciones clínicas, los resultados de las pruebas epicutáneas, las reacciones cruzadas existentes y las fuentes de exposición de dimetilfumarato que inducen estas dermatitis.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:23 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Fumaric acid esters" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Rostami Yazdi" 1 => "U. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 2 | 8 | 10 |
| 2024 October | 60 | 68 | 128 |
| 2024 September | 53 | 28 | 81 |
| 2024 August | 80 | 60 | 140 |
| 2024 July | 59 | 35 | 94 |
| 2024 June | 81 | 25 | 106 |
| 2024 May | 55 | 38 | 93 |
| 2024 April | 63 | 25 | 88 |
| 2024 March | 61 | 35 | 96 |
| 2024 February | 70 | 29 | 99 |
| 2024 January | 47 | 32 | 79 |
| 2023 December | 31 | 33 | 64 |
| 2023 November | 34 | 27 | 61 |
| 2023 October | 39 | 25 | 64 |
| 2023 September | 40 | 26 | 66 |
| 2023 August | 26 | 24 | 50 |
| 2023 July | 38 | 38 | 76 |
| 2023 June | 33 | 36 | 69 |
| 2023 May | 44 | 24 | 68 |
| 2023 April | 42 | 29 | 71 |
| 2023 March | 28 | 33 | 61 |
| 2023 February | 26 | 41 | 67 |
| 2023 January | 29 | 32 | 61 |
| 2022 December | 31 | 49 | 80 |
| 2022 November | 21 | 27 | 48 |
| 2022 October | 16 | 28 | 44 |
| 2022 September | 16 | 37 | 53 |
| 2022 August | 22 | 36 | 58 |
| 2022 July | 27 | 40 | 67 |
| 2022 June | 13 | 29 | 42 |
| 2022 May | 45 | 54 | 99 |
| 2022 April | 40 | 61 | 101 |
| 2022 March | 50 | 63 | 113 |
| 2022 February | 43 | 50 | 93 |
| 2022 January | 32 | 77 | 109 |
| 2021 December | 31 | 53 | 84 |
| 2021 November | 43 | 68 | 111 |
| 2021 October | 64 | 84 | 148 |
| 2021 September | 45 | 61 | 106 |
| 2021 August | 24 | 80 | 104 |
| 2021 July | 31 | 57 | 88 |
| 2021 June | 27 | 51 | 78 |
| 2021 May | 34 | 42 | 76 |
| 2021 April | 44 | 85 | 129 |
| 2021 March | 54 | 38 | 92 |
| 2021 February | 64 | 40 | 104 |
| 2021 January | 45 | 24 | 69 |
| 2020 December | 27 | 33 | 60 |
| 2020 November | 33 | 36 | 69 |
| 2020 October | 19 | 27 | 46 |
| 2020 September | 25 | 22 | 47 |
| 2020 August | 22 | 35 | 57 |
| 2020 July | 17 | 18 | 35 |
| 2020 June | 24 | 28 | 52 |
| 2020 May | 26 | 27 | 53 |
| 2020 April | 24 | 20 | 44 |
| 2020 March | 29 | 25 | 54 |
| 2020 February | 2 | 4 | 6 |
| 2020 January | 0 | 8 | 8 |
| 2019 December | 0 | 11 | 11 |
| 2019 November | 0 | 6 | 6 |
| 2019 October | 0 | 4 | 4 |
| 2019 September | 0 | 8 | 8 |
| 2019 August | 0 | 3 | 3 |
| 2019 July | 0 | 6 | 6 |
| 2019 June | 0 | 11 | 11 |
| 2019 May | 2 | 59 | 61 |
| 2019 April | 0 | 3 | 3 |
| 2019 March | 0 | 10 | 10 |
| 2019 February | 0 | 2 | 2 |
| 2018 April | 0 | 1 | 1 |
| 2018 February | 22 | 4 | 26 |
| 2018 January | 44 | 7 | 51 |
| 2017 December | 36 | 10 | 46 |
| 2017 November | 23 | 13 | 36 |
| 2017 October | 29 | 8 | 37 |
| 2017 September | 16 | 5 | 21 |
| 2017 August | 18 | 16 | 34 |
| 2017 July | 17 | 11 | 28 |
| 2017 June | 19 | 17 | 36 |
| 2017 May | 21 | 14 | 35 |
| 2017 April | 11 | 22 | 33 |
| 2017 March | 19 | 24 | 43 |
| 2017 February | 13 | 13 | 26 |
| 2017 January | 11 | 10 | 21 |
| 2016 December | 34 | 25 | 59 |
| 2016 November | 22 | 20 | 42 |
| 2016 October | 30 | 35 | 65 |
| 2016 September | 37 | 25 | 62 |
| 2016 August | 53 | 13 | 66 |
| 2016 July | 63 | 20 | 83 |
| 2016 June | 8 | 0 | 8 |
| 2016 May | 10 | 26 | 36 |
| 2016 April | 4 | 9 | 13 |
| 2016 March | 6 | 10 | 16 |
| 2016 February | 4 | 8 | 12 |
| 2016 January | 10 | 12 | 22 |
| 2015 December | 10 | 1 | 11 |
| 2015 November | 7 | 1 | 8 |
| 2015 October | 11 | 2 | 13 |
| 2015 September | 5 | 8 | 13 |
| 2015 August | 15 | 4 | 19 |
| 2015 July | 34 | 23 | 57 |
| 2015 June | 37 | 18 | 55 |
| 2015 May | 96 | 39 | 135 |
| 2015 April | 51 | 19 | 70 |
| 2015 March | 50 | 13 | 63 |
| 2015 February | 43 | 24 | 67 |
| 2015 January | 28 | 26 | 54 |
| 2014 December | 34 | 16 | 50 |
| 2014 November | 29 | 15 | 44 |
| 2014 October | 35 | 29 | 64 |
| 2014 September | 41 | 16 | 57 |
| 2014 August | 40 | 19 | 59 |
| 2014 July | 53 | 21 | 74 |
| 2014 June | 54 | 17 | 71 |
| 2014 May | 60 | 17 | 77 |
| 2014 April | 45 | 14 | 59 |
| 2014 March | 63 | 18 | 81 |
| 2014 February | 42 | 17 | 59 |
| 2014 January | 52 | 40 | 92 |
| 2013 December | 47 | 23 | 70 |
| 2013 November | 32 | 18 | 50 |
| 2013 October | 35 | 30 | 65 |
| 2013 September | 48 | 34 | 82 |
| 2013 August | 39 | 44 | 83 |
| 2013 July | 52 | 38 | 90 |
| 2013 June | 29 | 45 | 74 |
| 2013 May | 29 | 37 | 66 |
| 2013 April | 40 | 56 | 96 |
| 2013 March | 46 | 50 | 96 |
| 2013 February | 26 | 24 | 50 |
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