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Umbert Millet" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Galvany Rossell" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Salleras Redonnet" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Umbert Millet" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010705837?idApp=UINPBA000044" "url" => "/15782190/0000010100000001/v1_201304241512/S1578219010705837/v1_201304241512/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219010705813" "issn" => "15782190" "doi" => "10.1016/S1578-2190(10)70581-3" "estado" => "S300" "fechaPublicacion" => "2010-01-01" "aid" => "70581" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2010;101:59-75" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3368 "formatos" => array:3 [ "EPUB" => 39 "HTML" => 2352 "PDF" => 977 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "Epidemiology of Contact Dermatitis: Prevalence of Sensitization to Different Allergens and Associated Factors" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "59" "paginaFinal" => "75" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Epidemiología de la dermatitis de contacto: prevalencia de sensibilización a diferentes alérgenos y factores asociados" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M<span class="elsevierStyleSup">a</span>.T. Bordel-Gómez, A. Miranda-Romero, J. Castrodeza-Sanz" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M<span class="elsevierStyleSup">a</span>.T." "apellidos" => "Bordel-Gómez" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Miranda-Romero" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Castrodeza-Sanz" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010705813?idApp=UINPBA000044" "url" => "/15782190/0000010100000001/v1_201304241512/S1578219010705813/v1_201304241512/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>" "titulo" => "Nelson Syndrome: A Rare Cause of Generalized Hyperpigmentation of the Skin" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "76" "paginaFinal" => "80" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "R. Barabash, F.G. Moreno-Suárez, L. Rodríguez, A.M. Molina, J. Conejo-Mir" "autores" => array:5 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Barabash" "email" => array:1 [ 0 => "romanbarabash@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "F.G." "apellidos" => "Moreno-Suárez" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Rodríguez" ] 3 => array:2 [ "nombre" => "A.M." "apellidos" => "Molina" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Conejo-Mir" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Aspectos prácticos de la quinacrina como tratamiento del lupus eritematoso cutáneo: serie de casos" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-02-03" "fechaAceptado" => "2009-04-30" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84651" "palabras" => array:3 [ 0 => "Nelson syndrome" 1 => "Hyperpigmentation" 2 => "Adrenalectomy" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84650" "palabras" => array:3 [ 0 => "Síndrome de Nelson" 1 => "Hiperpigmentación" 2 => "Suprarrenalectomía" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Nelson syndrome is a rare cause of generalized mucocutaneous hyperpigmentation. Its clinical manifestations are due to excessive secretion of adrenocorticotropic hormone from a pituitary adenoma, which develops after bilateral therapeutic adrenalectomy. As this operation has fallen into disuse, Nelson syndrome is now extremely rare and difficult to recognize. We present a very severe case of generalized hyperpigmentation due to Nelson syndrome in a 37-year-old woman.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El síndrome de Nelson (SN) supone una causa infrecuente de hiperpigmentación mucocutánea generalizada, cuyas manifestaciones clínicas se derivan de la secreción excesiva de corticotropina por un adenoma hipofisario secundario a la realización de una suprarrenalectomía bilateral terapéutica. Debido a que esta intervención quirúrgica ha caído en desuso en la actualidad, su presentación es hoy sumamente rara y poco reconocible. Presentamos un caso muy grave de hiperpigmentación generalizada por SN en una paciente de 37 años.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "ACTH-producing tumor of the pituitary gland" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.H. Nelson" 1 => "J.W. Meakin" 2 => "J.B. Dealy" 3 => "D.D. Matson" 4 => "K. Emerson" 5 => "G.W. 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Year/Month | Html | Total | |
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2024 November | 9 | 11 | 20 |
2024 October | 63 | 72 | 135 |
2024 September | 93 | 36 | 129 |
2024 August | 136 | 74 | 210 |
2024 July | 76 | 48 | 124 |
2024 June | 78 | 60 | 138 |
2024 May | 74 | 57 | 131 |
2024 April | 62 | 51 | 113 |
2024 March | 73 | 53 | 126 |
2024 February | 70 | 68 | 138 |
2024 January | 63 | 81 | 144 |
2023 December | 63 | 45 | 108 |
2023 November | 69 | 51 | 120 |
2023 October | 65 | 52 | 117 |
2023 September | 55 | 27 | 82 |
2023 August | 42 | 33 | 75 |
2023 July | 40 | 74 | 114 |
2023 June | 61 | 52 | 113 |
2023 May | 46 | 103 | 149 |
2023 April | 50 | 31 | 81 |
2023 March | 47 | 33 | 80 |
2023 February | 48 | 32 | 80 |
2023 January | 40 | 32 | 72 |
2022 December | 60 | 64 | 124 |
2022 November | 30 | 48 | 78 |
2022 October | 23 | 31 | 54 |
2022 September | 42 | 42 | 84 |
2022 August | 46 | 46 | 92 |
2022 July | 23 | 30 | 53 |
2022 June | 35 | 24 | 59 |
2022 May | 35 | 42 | 77 |
2022 April | 48 | 42 | 90 |
2022 March | 29 | 48 | 77 |
2022 February | 30 | 31 | 61 |
2022 January | 33 | 44 | 77 |
2021 December | 18 | 55 | 73 |
2021 November | 37 | 47 | 84 |
2021 October | 43 | 59 | 102 |
2021 September | 24 | 40 | 64 |
2021 August | 33 | 33 | 66 |
2021 July | 38 | 35 | 73 |
2021 June | 30 | 26 | 56 |
2021 May | 27 | 24 | 51 |
2021 April | 56 | 40 | 96 |
2021 March | 72 | 33 | 105 |
2021 February | 65 | 22 | 87 |
2021 January | 39 | 19 | 58 |
2020 December | 39 | 14 | 53 |
2020 November | 37 | 24 | 61 |
2020 October | 25 | 12 | 37 |
2020 September | 15 | 16 | 31 |
2020 August | 20 | 19 | 39 |
2020 July | 15 | 10 | 25 |
2020 June | 29 | 29 | 58 |
2020 May | 19 | 27 | 46 |
2020 April | 20 | 23 | 43 |
2020 March | 19 | 19 | 38 |
2020 February | 1 | 3 | 4 |
2020 January | 0 | 9 | 9 |
2019 December | 0 | 7 | 7 |
2019 November | 0 | 8 | 8 |
2019 October | 0 | 1 | 1 |
2019 September | 0 | 18 | 18 |
2019 August | 0 | 16 | 16 |
2019 July | 0 | 11 | 11 |
2019 June | 0 | 9 | 9 |
2019 May | 1 | 43 | 44 |
2019 April | 0 | 6 | 6 |
2019 March | 0 | 7 | 7 |
2019 February | 0 | 3 | 3 |
2018 August | 0 | 2 | 2 |
2018 July | 0 | 1 | 1 |
2018 June | 0 | 1 | 1 |
2018 May | 0 | 7 | 7 |
2018 March | 1 | 1 | 2 |
2018 February | 9 | 3 | 12 |
2018 January | 12 | 7 | 19 |
2017 December | 15 | 5 | 20 |
2017 November | 11 | 10 | 21 |
2017 October | 13 | 9 | 22 |
2017 September | 14 | 10 | 24 |
2017 August | 21 | 13 | 34 |
2017 July | 21 | 6 | 27 |
2017 June | 25 | 18 | 43 |
2017 May | 27 | 17 | 44 |
2017 April | 27 | 7 | 34 |
2017 March | 21 | 25 | 46 |
2017 February | 12 | 8 | 20 |
2017 January | 10 | 12 | 22 |
2016 December | 22 | 12 | 34 |
2016 November | 26 | 8 | 34 |
2016 October | 25 | 8 | 33 |
2016 September | 31 | 13 | 44 |
2016 August | 30 | 5 | 35 |
2016 July | 35 | 9 | 44 |
2016 June | 9 | 10 | 19 |
2016 May | 5 | 7 | 12 |
2016 April | 4 | 8 | 12 |
2016 March | 11 | 10 | 21 |
2016 February | 3 | 15 | 18 |
2016 January | 8 | 13 | 21 |
2015 December | 17 | 5 | 22 |
2015 November | 10 | 6 | 16 |
2015 October | 4 | 3 | 7 |
2015 September | 9 | 5 | 14 |
2015 August | 9 | 4 | 13 |
2015 July | 34 | 8 | 42 |
2015 June | 33 | 9 | 42 |
2015 May | 91 | 18 | 109 |
2015 April | 53 | 21 | 74 |
2015 March | 45 | 10 | 55 |
2015 February | 36 | 18 | 54 |
2015 January | 26 | 26 | 52 |
2014 December | 28 | 10 | 38 |
2014 November | 26 | 20 | 46 |
2014 October | 32 | 12 | 44 |
2014 September | 39 | 21 | 60 |
2014 August | 40 | 15 | 55 |
2014 July | 40 | 18 | 58 |
2014 June | 38 | 9 | 47 |
2014 May | 39 | 17 | 56 |
2014 April | 39 | 7 | 46 |
2014 March | 53 | 17 | 70 |
2014 February | 35 | 15 | 50 |
2014 January | 36 | 15 | 51 |
2013 December | 43 | 14 | 57 |
2013 November | 22 | 21 | 43 |
2013 October | 34 | 19 | 53 |
2013 September | 42 | 20 | 62 |
2013 August | 31 | 24 | 55 |
2013 July | 47 | 30 | 77 |
2013 June | 37 | 39 | 76 |
2013 May | 32 | 25 | 57 |
2013 April | 26 | 42 | 68 |
2013 March | 38 | 46 | 84 |
2013 February | 15 | 25 | 40 |