Case reports
Photodynamic Therapy for Actinic Cheilitis
Tratamiento de Queilitis Actínicas con Terapia Fotodinámica
E. Castaño
, A. Comunión, D. Arias, R. Miñano, A. Romero, J. Borbujo
Corresponding author
ecastano.hflr@salud.madrid.org
Correspondence: Servicio de Dermatología. Hospital de Fuenlabrada. Camino del Molino 2. 28942 Fuenlabrada, Madrid, Spain.
Correspondence: Servicio de Dermatología. Hospital de Fuenlabrada. Camino del Molino 2. 28942 Fuenlabrada, Madrid, Spain.
Servicio de Dermatología, Hospital de Fuenlabrada, Fuenlabrada, Madrid, Spain
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"apellidos" => "Toribio" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009705608?idApp=UINPBA000044" "url" => "/15782190/0000010000000010/v1_201304241509/S1578219009705608/v1_201304241509/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case reports</span>" "titulo" => "Photodynamic Therapy for Actinic Cheilitis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "895" "paginaFinal" => "898" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "E. Castaño, A. Comunión, D. Arias, R. Miñano, A. Romero, J. Borbujo" "autores" => array:6 [ 0 => array:4 [ "nombre" => "E." "apellidos" => "Castaño" "email" => array:1 [ 0 => "ecastano.hflr@salud.madrid.org" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Comunión" ] 2 => array:2 [ "nombre" => "D." "apellidos" => "Arias" ] 3 => array:2 [ "nombre" => "R." "apellidos" => "Miñano" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Romero" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Borbujo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospital de Fuenlabrada, Fuenlabrada, Madrid, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología. Hospital de Fuenlabrada. Camino del Molino 2. 28942 Fuenlabrada, Madrid, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tratamiento de Queilitis Actínicas con Terapia Fotodinámica" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2009-04-16" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84622" "palabras" => array:3 [ 0 => "actinic cheilitis" 1 => "treatment" 2 => "photodynamic therapy" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84621" "palabras" => array:3 [ 0 => "queilitis actínica" 1 => "tratamiento" 2 => "terapia fotodinámica" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Actinic cheilitis is a subtype of actinic keratosis that mainly affects the lower lip and has a higher risk of malignant transformation. Its location on the labial mucosa influences the therapeutic approach. Vermilionectomy requires local or general anesthetic and is associated with a risk of an unsightly scar, and the treatment with 5-fluorouracil or imiquimod lasts for several weeks and the inflammatory reaction can be very intense. A number of authors have used photodynamic therapy as an alternative to the usual treatments. We present 3 patients with histologically confirmed actinic cheilitis treated using photodynamic therapy with methyl aminolevulinic acid as the photosensitizer and red light at 630 nm. The clinical response was good, with no recurrences after 3 to 6 months of follow-up. Our experience supports the use of photodynamic therapy as a good alternative for the treatment of actinic cheilitis.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La queilitis actínica es un subtipo de queratosis actínica que afecta fundamentalmente al labio inferior y tiene un riesgo incrementado de transformación carcinomatosa. La localización en la mucosa labial condiciona las distintas posibilidades terapéuticas. La bermellectomía obliga a realizar anestesia local o general y se asocia con un riesgo de cicatriz inestética; el tratamiento con 5-fluorouracilo o imiquimod se prolonga a lo largo de varias semanas y la reacción inflamatoria puede ser muy intensa. Varios autores han empleado la terapia fotodinámica como una alternativa a los tratamientos habituales. Presentamos a tres pacientes con queilitis actínica confirmada histológicamente que fueron tratados con terapia fotodinámica utilizando ácido metilaminolevulínico como fotosensibilizante y luz roja de 630 nm. La respuesta clínica fue buena, con ausencia de recidiva al cabo de 3 a 6 meses de seguimiento. Nuestra experiencia avala el empleo de la terapia fotodinámica como una buena alternativa terapéutica para la queilitis actínica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:12 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic cheilitis: clinical and pathologic characteristics in 65 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Markopoulos" 1 => "E. Albanidou-Farmaki" 2 => "I. 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| 2019 November | 0 | 2 | 2 |
| 2019 October | 0 | 3 | 3 |
| 2019 September | 0 | 6 | 6 |
| 2019 August | 0 | 6 | 6 |
| 2019 July | 0 | 5 | 5 |
| 2019 June | 0 | 9 | 9 |
| 2019 May | 0 | 65 | 65 |
| 2019 April | 0 | 43 | 43 |
| 2019 March | 0 | 5 | 5 |
| 2019 February | 0 | 16 | 16 |
| 2019 January | 0 | 14 | 14 |
| 2018 December | 0 | 17 | 17 |
| 2018 November | 0 | 5 | 5 |
| 2018 September | 0 | 4 | 4 |
| 2018 August | 0 | 11 | 11 |
| 2018 July | 0 | 10 | 10 |
| 2018 June | 0 | 8 | 8 |
| 2018 May | 0 | 10 | 10 |
| 2018 April | 0 | 6 | 6 |
| 2018 March | 1 | 19 | 20 |
| 2018 February | 20 | 26 | 46 |
| 2018 January | 10 | 35 | 45 |
| 2017 December | 23 | 29 | 52 |
| 2017 November | 10 | 22 | 32 |
| 2017 October | 12 | 17 | 29 |
| 2017 September | 16 | 48 | 64 |
| 2017 August | 24 | 26 | 50 |
| 2017 July | 21 | 23 | 44 |
| 2017 June | 13 | 42 | 55 |
| 2017 May | 12 | 29 | 41 |
| 2017 April | 18 | 21 | 39 |
| 2017 March | 17 | 27 | 44 |
| 2017 February | 12 | 19 | 31 |
| 2017 January | 11 | 31 | 42 |
| 2016 December | 33 | 15 | 48 |
| 2016 November | 33 | 20 | 53 |
| 2016 October | 37 | 27 | 64 |
| 2016 September | 34 | 29 | 63 |
| 2016 August | 42 | 39 | 81 |
| 2016 July | 44 | 35 | 79 |
| 2016 June | 8 | 14 | 22 |
| 2016 May | 8 | 18 | 26 |
| 2016 April | 6 | 11 | 17 |
| 2016 March | 4 | 19 | 23 |
| 2016 February | 4 | 24 | 28 |
| 2016 January | 14 | 20 | 34 |
| 2015 December | 11 | 14 | 25 |
| 2015 November | 8 | 2 | 10 |
| 2015 October | 8 | 17 | 25 |
| 2015 September | 6 | 6 | 12 |
| 2015 August | 10 | 9 | 19 |
| 2015 July | 27 | 10 | 37 |
| 2015 June | 32 | 27 | 59 |
| 2015 May | 59 | 31 | 90 |
| 2015 April | 28 | 35 | 63 |
| 2015 March | 37 | 20 | 57 |
| 2015 February | 30 | 19 | 49 |
| 2015 January | 23 | 28 | 51 |
| 2014 December | 20 | 10 | 30 |
| 2014 November | 24 | 11 | 35 |
| 2014 October | 33 | 29 | 62 |
| 2014 September | 31 | 23 | 54 |
| 2014 August | 28 | 26 | 54 |
| 2014 July | 42 | 17 | 59 |
| 2014 June | 41 | 15 | 56 |
| 2014 May | 49 | 13 | 62 |
| 2014 April | 46 | 11 | 57 |
| 2014 March | 44 | 25 | 69 |
| 2014 February | 22 | 28 | 50 |
| 2014 January | 32 | 27 | 59 |
| 2013 December | 24 | 28 | 52 |
| 2013 November | 29 | 32 | 61 |
| 2013 October | 31 | 36 | 67 |
| 2013 September | 25 | 30 | 55 |
| 2013 August | 26 | 37 | 63 |
| 2013 July | 41 | 59 | 100 |
| 2013 June | 37 | 55 | 92 |
| 2013 May | 25 | 33 | 58 |
| 2013 April | 31 | 43 | 74 |
| 2013 March | 32 | 24 | 56 |
| 2013 February | 16 | 14 | 30 |
| 2013 January | 2 | 1 | 3 |
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