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"documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Dermosifiliogr. 2009;100:749-55" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3261 "formatos" => array:3 [ "EPUB" => 37 "HTML" => 1421 "PDF" => 1803 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review</span>" "titulo" => "Introduction to Clinical Research in Dermatology: The Link Between Clinical Practice and Research" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "749" "paginaFinal" => "755" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Introducción a la Investigación Clínica en Dermatología. Un Nexo Entre Clínica e Investigación" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. García-Doval, L. Naldi" "autores" => array:2 [ 0 => array:2 [ "nombre" => "I." "apellidos" => "García-Doval" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Naldi" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009701696?idApp=UINPBA000044" "url" => "/15782190/0000010000000009/v1_201304241507/S1578219009701696/v1_201304241507/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Actas 1909-2009</span>" "titulo" => "Infectious Nature Of Leprosy by Juan De Azua" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "756" "paginaFinal" => "758" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J. Terencio de las Aguas" "autores" => array:1 [ 0 => array:4 [ "nombre" => "J." "apellidos" => "Terencio de las Aguas" "email" => array:1 [ 0 => "drjoseterencio@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Honorary Medical Director of Fontilles Sanatorium. Council Member, International Society of Leprology. Member of the Royal Academy of Medicine of Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Marqués de Campo, 37-3°, 03700 Denia, Alicante, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Contagiosidad de la Lepra, por Juan de Azúa" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84589" "palabras" => array:2 [ 0 => "leprosy" 1 => "communicable diseases" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84590" "palabras" => array:2 [ 0 => "lepra" 1 => "contagiosidad" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">In this article by Juan de Azua, published in the second issue of Actas Dermosifiliográficas in 1909, the author reports his experience in 139 patients, most of them from Hospital San Juan de Dios, Madrid, Spain, and states he is sure that leprosy is a contagious disease. He discusses the factors related to contagion, which occurs in a closed and family environment, emphasizing socioeconomic factors such as hygiene and promiscuity. He considers direct contact to be important, though also recognizing indirect contact through drinks and food; he totally rejects a hereditary mechanism. Epidemiologically, he draws attention to the higher prevalence of the disease in Andalusia, though not forgetting “<span class="elsevierStyleItalic">La Lepra de Ultramar</span> [leprosy from distant lands]”—32 cases in Spaniards in Cuba and the Philippines. He believes isolation in hospitals or special sanatoriums, such as San Juan de Dios or San Lázaro in Santiago, Granada, and Seville, to be the best prophylaxis, and he considers it would be appropriate to create “Hospitals for poor lepers.”</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">En este artículo de Juan de Azúa, publicado en el número 2 de «Actas Dermosifiliográficas» de 1909, el autor se manifiesta totalmente seguro de la contagiosidad de la lepra, exponiendo su experiencia en 139 enfermos, la mayoría de San Juan de Dios. Comenta los factores de contagio que es íntimo y familiar, destacando los factores socioeconómicos como la higiene y la promiscuidad. Considera muy importante el contacto directo aunque sin olvidar el indirecto como las bebidas y alimentos, descartando totalmente la herencia. Epidemiológicamente señala la mayor endemia en Andalucía sin olvidar «La Lepra de Ultramar», 32 casos contraídos por españoles en Cuba y Filipinas. Considera que la mejor profilaxis es el aislamiento en hospitales o en «asilos especiales» como San Juan de Dios, San Lázaro de Santiago, Granada y Sevilla, considerando apropiado la construcción de «Hospitales para Lazarinos pobres».</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Contagiosidad de la lepra" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J. Azúa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "1909" "volumen" => "2" "paginaInicial" => "109" "paginaFinal" => "114" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Serodiagnóstico de la lepra" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J. Azúa" 1 => "J.S. Covisa" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "1909" "volumen" => "2" "paginaInicial" => "144" "paginaFinal" => "146" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010000000009/v1_201304241507/S1578219009701702/v1_201304241507/en/main.assets" "Apartado" => array:4 [ "identificador" => "6241" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Actas 1909-2009" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010000000009/v1_201304241507/S1578219009701702/v1_201304241507/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009701702?idApp=UINPBA000044" ]
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