Correspondence: Servicio de Dermatología Hospital de la Santa Creu i de Sant Pau, Sant Antoni Maria Claret, 167, 08025 Barcelona, Spain.
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The role of systemic treatment in the management of psoriasis is being reviewed on the basis of a large volume of scientific evidence on the efficacy and safety of biologic agents, and new therapeutic goals and strategies are being devised for patients with moderate to severe psoriasis. This has led to the need to establish severity criteria that will provide the rationale for the indication of the different systemic agents currently available for the treatment of moderate to severe psoriasis, as well as therapeutic goals, efficacy measures, therapeutic strategies, screening protocols, and choice of treatment based on the risk-benefit ratio of the different agents. These criteria must be established through consensus by experienced dermatologists and based on available scientific evidence. The present document reflects the consensus of the Spanish Psoriasis Group on these different issues in the management of moderate to severe psoriasis.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El tratamiento de la psoriasis se ha visto revolucionado por la introducción de los agentes biológicos, que permiten obtener blanqueamientos y mejorías a largo plazo sin el riesgo de toxicidad que ha venido limitando el tratamiento de estos pacientes con agentes sistémicos clásicos. Se ha acumulado abundante evidencia científica con respecto a la eficacia y seguridad de los agentes biológicos, que ha llevado a revisar el papel del tratamiento sistémico en general y ha permitido establecer nuevos objetivos y estrategias terapéuticas en los pacientes con psoriasis moderada a grave. En este contexto nuevo se hace necesario establecer, de forma consensuada por especialistas expertos y basada en la evidencia científica disponible, criterios de gravedad que justifiquen la indicación de los diferentes tratamientos sistémicos actualmente disponibles para la psoriasis, así como objetivos terapéuticos y parámetros de eficacia, estrategias de tratamiento, cribaje de los pacientes y selección del tratamiento basada en criterios de beneficio/riesgo. El presente documento recoge el consenso del Grupo Español de Psoriasis en estos diferentes aspectos del manejo de la psoriasis moderada a grave.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">The Spanish Psoriasis Group is a working group of the Spanish Academy of Dermatology and Venereology. The 50 members of the group are dermatologists working in hospital settings who have special expertise in the treatment of patients with psoriasis and are involved in clinical and therapeutic research in this specialized area.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:34 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevalence of psoriasis in Spain (Epiderma Project: phase I)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Ferrándiz" 1 => "X. Bordas" 2 => "V. García-Patos" 3 => "S. Puig" 4 => "R. Pujol" 5 => "A. 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Year/Month | Html | Total | |
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2024 November | 1 | 5 | 6 |
2024 October | 75 | 61 | 136 |
2024 September | 54 | 32 | 86 |
2024 August | 84 | 62 | 146 |
2024 July | 51 | 40 | 91 |
2024 June | 55 | 40 | 95 |
2024 May | 47 | 38 | 85 |
2024 April | 41 | 42 | 83 |
2024 March | 42 | 45 | 87 |
2024 February | 42 | 44 | 86 |
2024 January | 45 | 47 | 92 |
2023 December | 37 | 41 | 78 |
2023 November | 43 | 38 | 81 |
2023 October | 31 | 27 | 58 |
2023 September | 28 | 26 | 54 |
2023 August | 22 | 19 | 41 |
2023 July | 36 | 34 | 70 |
2023 June | 35 | 39 | 74 |
2023 May | 57 | 42 | 99 |
2023 April | 27 | 31 | 58 |
2023 March | 65 | 41 | 106 |
2023 February | 19 | 23 | 42 |
2023 January | 35 | 27 | 62 |
2022 December | 31 | 53 | 84 |
2022 November | 14 | 41 | 55 |
2022 October | 11 | 18 | 29 |
2022 September | 13 | 41 | 54 |
2022 August | 13 | 40 | 53 |
2022 July | 19 | 30 | 49 |
2022 June | 15 | 39 | 54 |
2022 May | 25 | 48 | 73 |
2022 April | 33 | 45 | 78 |
2022 March | 37 | 51 | 88 |
2022 February | 27 | 33 | 60 |
2022 January | 24 | 45 | 69 |
2021 December | 27 | 58 | 85 |
2021 November | 27 | 62 | 89 |
2021 October | 21 | 54 | 75 |
2021 September | 31 | 50 | 81 |
2021 August | 17 | 28 | 45 |
2021 July | 20 | 42 | 62 |
2021 June | 18 | 35 | 53 |
2021 May | 19 | 44 | 63 |
2021 April | 74 | 56 | 130 |
2021 March | 70 | 45 | 115 |
2021 February | 37 | 25 | 62 |
2021 January | 29 | 20 | 49 |
2020 December | 27 | 20 | 47 |
2020 November | 18 | 22 | 40 |
2020 October | 19 | 23 | 42 |
2020 September | 11 | 19 | 30 |
2020 August | 31 | 30 | 61 |
2020 July | 26 | 20 | 46 |
2020 June | 22 | 26 | 48 |
2020 May | 26 | 25 | 51 |
2020 April | 19 | 22 | 41 |
2020 March | 24 | 20 | 44 |
2020 February | 0 | 6 | 6 |
2020 January | 0 | 3 | 3 |
2019 December | 0 | 7 | 7 |
2019 November | 0 | 7 | 7 |
2019 September | 0 | 1 | 1 |
2019 August | 0 | 3 | 3 |
2019 July | 0 | 1 | 1 |
2019 June | 0 | 12 | 12 |
2019 May | 0 | 58 | 58 |
2019 April | 0 | 8 | 8 |
2019 March | 0 | 16 | 16 |
2019 February | 0 | 8 | 8 |
2018 November | 0 | 5 | 5 |
2018 September | 0 | 3 | 3 |
2018 August | 0 | 5 | 5 |
2018 July | 0 | 4 | 4 |
2018 June | 0 | 7 | 7 |
2018 May | 0 | 7 | 7 |
2018 April | 0 | 4 | 4 |
2018 March | 0 | 6 | 6 |
2018 February | 9 | 10 | 19 |
2018 January | 17 | 12 | 29 |
2017 December | 20 | 22 | 42 |
2017 November | 10 | 18 | 28 |
2017 October | 12 | 30 | 42 |
2017 September | 13 | 24 | 37 |
2017 August | 14 | 25 | 39 |
2017 July | 13 | 19 | 32 |
2017 June | 25 | 20 | 45 |
2017 May | 28 | 37 | 65 |
2017 April | 22 | 17 | 39 |
2017 March | 24 | 46 | 70 |
2017 February | 18 | 21 | 39 |
2017 January | 8 | 19 | 27 |
2016 December | 28 | 18 | 46 |
2016 November | 26 | 33 | 59 |
2016 October | 24 | 35 | 59 |
2016 September | 33 | 28 | 61 |
2016 August | 33 | 18 | 51 |
2016 July | 30 | 12 | 42 |
2016 June | 7 | 15 | 22 |
2016 May | 6 | 17 | 23 |
2016 April | 6 | 1 | 7 |
2016 March | 4 | 5 | 9 |
2016 February | 6 | 2 | 8 |
2016 January | 12 | 4 | 16 |
2015 December | 6 | 2 | 8 |
2015 November | 11 | 6 | 17 |
2015 October | 4 | 8 | 12 |
2015 September | 6 | 8 | 14 |
2015 August | 12 | 2 | 14 |
2015 July | 27 | 1 | 28 |
2015 June | 36 | 16 | 52 |
2015 May | 73 | 25 | 98 |
2015 April | 30 | 41 | 71 |
2015 March | 33 | 29 | 62 |
2015 February | 22 | 24 | 46 |
2015 January | 25 | 23 | 48 |
2014 December | 29 | 30 | 59 |
2014 November | 17 | 16 | 33 |
2014 October | 38 | 22 | 60 |
2014 September | 29 | 15 | 44 |
2014 August | 34 | 17 | 51 |
2014 July | 37 | 23 | 60 |
2014 June | 45 | 15 | 60 |
2014 May | 44 | 16 | 60 |
2014 April | 47 | 12 | 59 |
2014 March | 60 | 21 | 81 |
2014 February | 42 | 23 | 65 |
2014 January | 42 | 24 | 66 |
2013 December | 45 | 30 | 75 |
2013 November | 31 | 36 | 67 |
2013 October | 26 | 47 | 73 |
2013 September | 32 | 34 | 66 |
2013 August | 23 | 44 | 67 |
2013 July | 39 | 33 | 72 |
2013 June | 30 | 38 | 68 |
2013 May | 19 | 33 | 52 |
2013 April | 22 | 46 | 68 |
2013 March | 37 | 28 | 65 |
2013 February | 36 | 8 | 44 |
2013 January | 10 | 5 | 15 |