Review article
Radiotherapy inb Dermatology
Radioterapia en Dermatología
A. Marína,
, E. Vargas-Díezb, L. Cerezoa
Corresponding author
amarin.hlpr@salud.madrid.org
Correspondence: Servicio de Oncología Radioterápica, Hospital Universitario de La Princesa, C/ Diego de León, 62, 28006 Madrid, Spain.
Correspondence: Servicio de Oncología Radioterápica, Hospital Universitario de La Princesa, C/ Diego de León, 62, 28006 Madrid, Spain.
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"apellidos" => "Marín" "email" => array:1 [ 0 => "amarin.hlpr@salud.madrid.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:3 [ "nombre" => "E." "apellidos" => "Vargas-Díez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Cerezo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Oncología Radioterápica, Hospital Universitario de La Princesa, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Universitario de La Princesa, Madrid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Oncología Radioterápica, Hospital Universitario de La Princesa, C/ Diego de León, 62, 28006 Madrid, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Radioterapia en Dermatología" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-07-07" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84420" "palabras" => array:4 [ 0 => "radiotherapy" 1 => "skin cancer" 2 => "electrons" 3 => "high-dose-rate brachytherapy" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84419" "palabras" => array:4 [ 0 => "radioterapia" 1 => "cáncer de piel" 2 => "electrones" 3 => "braquiterapia de alta tasa" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Ionizing radiation causes cell death through DNA damage and has a stronger effect on undifferentiated tumor cells with a high mitotic rate. The use of a fractionated radiotherapy regimen improves both efficacy and tolerance. In addition, greater fractionation, with lower doses per session, minimizes adverse effects. In the majority of tumors treated with radical radiotherapy, the tumor cells do not disappear immediately after treatment, and assessment of the final response to treatment before three months is premature. Radiotherapy is an important treatment modality in selected patients with skin cancer. Modern radiotherapy equipment and techniques achieve excellent rates of tumor control, associated with good cosmetic results, preserved function, and a low rate of complications. The choice of technique is determined by tumor size and site and the thickness. The techniques most widely used at the present time include external beam radiotherapy with linear accelerator sand high-dose-rate brachytherapy.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El mecanismo por el cual las radiaciones ionizantes producen muerte celular es el daño al ADN, que afecta más a las células tumorales de mayor actividad mitótica e indiferenciadas. La administración de radioterapia en dosis fraccionadas aumenta la eficacia y la tolerabilidad del tratamiento; esquemas más fraccionados en dosis bajas por sesión minimizan los efectos secundarios. La mayoría de los tumores irradiados en dosis radical no desaparecen de forma rápida al final del tratamiento. Una valoración de la respuesta definitiva antes de los tres meses es prematura. La radioterapia es un tratamiento importante en pacientes seleccionados con cáncer de piel. Se obtienen excelentes tasas de control tumoral, con buen resultado cosmético, preservación funcional e infrecuentes complicaciones con los modernos equipos y las técnicas de radioterapia. La elección de la técnica se determina por el tamaño, el espesor y la localización anatómica del tumor. Las técnicas actualmente más extendidas para el tratamiento del cáncer de piel son la radioterapia externa con electrones de acelerador lineal y la braquiterapia de alta tasa de dosis.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:77 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Basal cell carcinoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.S.M. Wong" 1 => "R.C. Strange" 2 => "J.T. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 0 | 2 | 2 |
| 2024 October | 57 | 56 | 113 |
| 2024 September | 56 | 48 | 104 |
| 2024 August | 90 | 63 | 153 |
| 2024 July | 62 | 49 | 111 |
| 2024 June | 49 | 39 | 88 |
| 2024 May | 57 | 45 | 102 |
| 2024 April | 65 | 30 | 95 |
| 2024 March | 42 | 51 | 93 |
| 2024 February | 42 | 46 | 88 |
| 2024 January | 49 | 53 | 102 |
| 2023 December | 31 | 48 | 79 |
| 2023 November | 43 | 61 | 104 |
| 2023 October | 36 | 50 | 86 |
| 2023 September | 35 | 39 | 74 |
| 2023 August | 31 | 26 | 57 |
| 2023 July | 46 | 81 | 127 |
| 2023 June | 38 | 50 | 88 |
| 2023 May | 37 | 63 | 100 |
| 2023 April | 32 | 48 | 80 |
| 2023 March | 21 | 47 | 68 |
| 2023 February | 26 | 34 | 60 |
| 2023 January | 24 | 35 | 59 |
| 2022 December | 31 | 50 | 81 |
| 2022 November | 23 | 42 | 65 |
| 2022 October | 16 | 31 | 47 |
| 2022 September | 18 | 38 | 56 |
| 2022 August | 16 | 39 | 55 |
| 2022 July | 12 | 43 | 55 |
| 2022 June | 11 | 42 | 53 |
| 2022 May | 17 | 54 | 71 |
| 2022 April | 29 | 58 | 87 |
| 2022 March | 36 | 64 | 100 |
| 2022 February | 15 | 43 | 58 |
| 2022 January | 22 | 47 | 69 |
| 2021 December | 20 | 42 | 62 |
| 2021 November | 33 | 58 | 91 |
| 2021 October | 38 | 54 | 92 |
| 2021 September | 32 | 46 | 78 |
| 2021 August | 22 | 32 | 54 |
| 2021 July | 21 | 37 | 58 |
| 2021 June | 25 | 28 | 53 |
| 2021 May | 16 | 24 | 40 |
| 2021 April | 27 | 26 | 53 |
| 2021 March | 71 | 24 | 95 |
| 2021 February | 70 | 22 | 92 |
| 2021 January | 47 | 18 | 65 |
| 2020 December | 18 | 21 | 39 |
| 2020 November | 22 | 21 | 43 |
| 2020 October | 11 | 12 | 23 |
| 2020 September | 22 | 5 | 27 |
| 2020 August | 85 | 21 | 106 |
| 2020 July | 66 | 10 | 76 |
| 2020 June | 36 | 27 | 63 |
| 2020 May | 24 | 31 | 55 |
| 2020 April | 13 | 25 | 38 |
| 2020 March | 19 | 23 | 42 |
| 2020 February | 0 | 15 | 15 |
| 2020 January | 0 | 7 | 7 |
| 2019 December | 0 | 5 | 5 |
| 2019 November | 0 | 5 | 5 |
| 2019 October | 0 | 7 | 7 |
| 2019 September | 0 | 2 | 2 |
| 2019 August | 0 | 8 | 8 |
| 2019 July | 0 | 8 | 8 |
| 2019 June | 0 | 3 | 3 |
| 2019 May | 0 | 36 | 36 |
| 2019 April | 0 | 2 | 2 |
| 2019 March | 0 | 6 | 6 |
| 2019 February | 0 | 3 | 3 |
| 2018 April | 0 | 1 | 1 |
| 2018 March | 2 | 1 | 3 |
| 2018 February | 17 | 13 | 30 |
| 2018 January | 16 | 8 | 24 |
| 2017 December | 33 | 13 | 46 |
| 2017 November | 28 | 9 | 37 |
| 2017 October | 13 | 6 | 19 |
| 2017 September | 15 | 10 | 25 |
| 2017 August | 22 | 9 | 31 |
| 2017 July | 17 | 10 | 27 |
| 2017 June | 23 | 11 | 34 |
| 2017 May | 17 | 10 | 27 |
| 2017 April | 18 | 4 | 22 |
| 2017 March | 24 | 12 | 36 |
| 2017 February | 10 | 6 | 16 |
| 2017 January | 12 | 12 | 24 |
| 2016 December | 21 | 12 | 33 |
| 2016 November | 31 | 10 | 41 |
| 2016 October | 33 | 16 | 49 |
| 2016 September | 30 | 12 | 42 |
| 2016 August | 31 | 11 | 42 |
| 2016 July | 20 | 11 | 31 |
| 2016 June | 6 | 12 | 18 |
| 2016 May | 8 | 26 | 34 |
| 2016 April | 7 | 18 | 25 |
| 2016 March | 9 | 12 | 21 |
| 2016 February | 8 | 11 | 19 |
| 2016 January | 5 | 11 | 16 |
| 2015 December | 9 | 11 | 20 |
| 2015 November | 11 | 9 | 20 |
| 2015 October | 4 | 11 | 15 |
| 2015 September | 8 | 8 | 16 |
| 2015 August | 21 | 5 | 26 |
| 2015 July | 45 | 7 | 52 |
| 2015 June | 44 | 43 | 87 |
| 2015 May | 73 | 9 | 82 |
| 2015 April | 49 | 20 | 69 |
| 2015 March | 36 | 14 | 50 |
| 2015 February | 36 | 15 | 51 |
| 2015 January | 44 | 12 | 56 |
| 2014 December | 54 | 15 | 69 |
| 2014 November | 22 | 13 | 35 |
| 2014 October | 44 | 19 | 63 |
| 2014 September | 30 | 15 | 45 |
| 2014 August | 44 | 15 | 59 |
| 2014 July | 48 | 27 | 75 |
| 2014 June | 60 | 14 | 74 |
| 2014 May | 51 | 16 | 67 |
| 2014 April | 51 | 15 | 66 |
| 2014 March | 62 | 20 | 82 |
| 2014 February | 30 | 26 | 56 |
| 2014 January | 48 | 18 | 66 |
| 2013 December | 45 | 21 | 66 |
| 2013 November | 21 | 21 | 42 |
| 2013 October | 27 | 31 | 58 |
| 2013 September | 32 | 47 | 79 |
| 2013 August | 34 | 54 | 88 |
| 2013 July | 28 | 44 | 72 |
| 2013 June | 24 | 37 | 61 |
| 2013 May | 26 | 28 | 54 |
| 2013 April | 32 | 30 | 62 |
| 2013 March | 35 | 27 | 62 |
| 2013 February | 33 | 13 | 46 |
| 2013 January | 11 | 3 | 14 |
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