Correspondence: Servicio de Dermatología, Hospital del Mar, c/ Passeig Maritím, 25-29, 08003 Barcelona.
was read the article
array:23 [ "pii" => "S1578219008703433" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70343-3" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70343" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2008" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Dermosifiliogr. 2008;99:671-82" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 5506 "formatos" => array:3 [ "EPUB" => 32 "HTML" => 1806 "PDF" => 3668 ] ] "itemSiguiente" => array:18 [ "pii" => "S1578219008703445" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70344-5" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70344" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2008;99:683-9" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 6963 "formatos" => array:3 [ "EPUB" => 34 "HTML" => 1544 "PDF" => 5385 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical dermatology</span>" "titulo" => "Antibiotic Prophylaxis in Dermatologic Surgery" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "683" "paginaFinal" => "689" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Profilaxis Antibiótica en Cirugía Dermatológica" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Yuste, A. Romo, P. de Unamuno" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Yuste" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Romo" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "de Unamuno" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703445?idApp=UINPBA000044" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703445/v1_201304241441/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219008703421" "issn" => "15782190" "doi" => "10.1016/S1578-2190(08)70342-1" "estado" => "S300" "fechaPublicacion" => "2008-11-01" "aid" => "70342" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2008;99:669-70" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2022 "formatos" => array:3 [ "EPUB" => 38 "HTML" => 1307 "PDF" => 677 ] ] "en" => array:8 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Opinion article</span>" "titulo" => "Surgical Training of Dermatologists" "tienePdf" => "en" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "669" "paginaFinal" => "670" ] ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Serrano" "autores" => array:1 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Serrano" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703421?idApp=UINPBA000044" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703421/v1_201304241441/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Review article</span>" "titulo" => "Xerosis: a Dysfunction of the Epidermal Barrier" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "671" "paginaFinal" => "682" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "D. Barco, A. Giménez-Arnau" "autores" => array:2 [ 0 => array:3 [ "nombre" => "D." "apellidos" => "Barco" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] ] ] 1 => array:4 [ "nombre" => "A." "apellidos" => "Giménez-Arnau" "email" => array:1 [ 0 => "agimenez@imas.imim.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff1" ] 1 => array:3 [ "entidad" => "Departamento de Dermatología, Hospital del Mar-IMIM, Barcelona Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff2" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología, Hospital del Mar, c/ Passeig Maritím, 25-29, 08003 Barcelona." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Xerosis: una Disfunción de la Barrera Epidérmica" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-02-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84294" "palabras" => array:5 [ 0 => "xerosis" 1 => "dry skin" 2 => "stratum corneum" 3 => "ceramides" 4 => "lipids" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84293" "palabras" => array:5 [ 0 => "xerosis" 1 => "piel seca" 2 => "estrato córneo" 3 => "ceramidas" 4 => "lípidos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Xerosis or dry skin is a common skin disorder among the general population. It is characterized clinically by rough, scaly, and often itchy skin. This disorder is present in the course of some dermatoses such as atopic dermatitis, although it can also occur in healthy individuals if a combination of certain etiologic factors is present. It is characterized pathophysiologically by a disrupted stratum corneum, dehydration, and impaired keratinocyte differentiation. Treatment of xerosis should seek to restore physiologic lipids in the epidermis and provide substances that facilitate epidermal differentiation.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La xerosis o piel seca es un trastorno cutáneo de alta prevalencia en la población general que se caracteriza clínicamente por una piel áspera, descamativa y habitualmente pruriginosa. Ciertas dermatosis como la dermatitis atópica cursan con este trastorno, aunque puede presentarse en individuos sanos si coinciden varios factores etiológicos. Fisiopatológicamente consiste en la modificación estructural del estrato córneo, su contenido en agua y un defecto en la diferenciación queratinocitaria. El tratamiento de la xerosis debiera buscar la recomposición de los lípidos fisiológicos de la epidermis y el aporte de sustancias que faciliten la diferenciación epidérmica.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:30 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eczema, ichthyosis, psoriasis: conditions of cornification" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S.R. Burdette-Taylor" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ostomy Wound Manage" "fecha" => "1995" "volumen" => "41" "paginaInicial" => "36" "paginaFinal" => "38" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7546119" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The management of dry skin with topical emollients–recent perspectives" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "E. Proksch" 1 => "J.M. Lachapelle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1610-0387.2005.05068.x" "Revista" => array:6 [ "tituloSerie" => "J Dtsch Dermatol Ges" "fecha" => "2005" "volumen" => "3" "paginaInicial" => "768" "paginaFinal" => "774" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16194154" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cholesterol synthesis is required for cutaneous barrier function in mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "K.R. Feingold" 1 => "M. Mao-Quian" 2 => "G.K. Menon" 3 => "S.S. Cho" 4 => "B.E. Brown" 5 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI114899" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "1990" "volumen" => "86" "paginaInicial" => "1738" "paginaFinal" => "1745" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2243142" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lipid content and lipid type as determinants of the epidermal permeability barrier" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Grubauer" 1 => "K.R. Feingold" 2 => "R.M. Harris" 3 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Lipid Res" "fecha" => "1989" "volumen" => "30" "paginaInicial" => "89" "paginaFinal" => "96" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2918253" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stratum corneum defensive functions: an integrated view" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P.M. Elias" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.0022-202X.2005.23668.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2005" "volumen" => "125" "paginaInicial" => "183" "paginaFinal" => "200" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16098026" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relationship between NMF (lactate and potassium) content and the physical properties of the stratum corneum in healthy subjects" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "N. Nakagawa" 1 => "S. Sakai" 2 => "M. Matsumoto" 3 => "K. Yamada" 4 => "M. Nagano" 5 => "T. Yuki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.0022-202X.2004.22317.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2004" "volumen" => "122" "paginaInicial" => "755" "paginaFinal" => "763" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15086563" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "How to choose a suitable emollient" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Clark" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pharm J" "fecha" => "2004" "volumen" => "273" "paginaInicial" => "351" "paginaFinal" => "353" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.V. Rawlings" 1 => "P.J. Matts" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1523-1747.2005.23726.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2005" "volumen" => "124" "paginaInicial" => "1099" "paginaFinal" => "1110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15955083" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low humidity and microtrauma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.J.G. Rycroft" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Ind Med" "fecha" => "1985" "volumen" => "8" "paginaInicial" => "371" "paginaFinal" => "373" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4073035" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ceramide and cholesterol composition of the skin of patients with atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. Di Nardo" 1 => "P. Werz" 2 => "A. Giannetti" 3 => "S. Deidenari" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Acta Dermatol Venereol" "fecha" => "1998" "volumen" => "78" "paginaInicial" => "27" "paginaFinal" => "30" ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Filaggrin mutations in children with severe atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "N. Morar" 1 => "W.O. Cookson" 2 => "J.I. Harper" 3 => "M.F. Moffatt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/sj.jid.5700739" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "2007" "volumen" => "127" "paginaInicial" => "1667" "paginaFinal" => "1672" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17301831" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The content of free amino acids in the stratum corneum is increased in senile xerosis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Takahashi" 1 => "T. Tezuka" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00403-003-0448-x" "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol Res" "fecha" => "2004" "volumen" => "295" "paginaInicial" => "448" "paginaFinal" => "452" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14762669" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in environmental humidity affect the water-holding property of the stratum corneum and its free amino acid content, and the expression of the filaggrin in the epidermis of hairless mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "C. Katagiri" 1 => "J. Sato" 2 => "J. Nomura" 3 => "M. Denda" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Dermatol Sci" "fecha" => "2003" "volumen" => "31" "paginaInicial" => "29" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12615361" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Signaling networks in barrier homeostasis: the mystery widens" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "P.M. Elias" 1 => "J.C. Ansel" 2 => "L.D. Woods" 3 => "K.R. Feingold" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1996" "volumen" => "132" "paginaInicial" => "1505" "paginaFinal" => "1506" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8961883" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidermal pathogenesis of inflammatory dermatoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.M. Elias" 1 => "L.D. Woods" 2 => "K.R. Feingold" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Contact Dermat" "fecha" => "1999" "volumen" => "10" "paginaInicial" => "119" "paginaFinal" => "126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10444104" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low humidity occupational dermatoses" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P.J.G. Rycroft" 1 => "W.D.L. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Contact Dermatitis" "fecha" => "1980" "volumen" => "6" "paginaInicial" => "488" "paginaFinal" => "492" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6452248" "web" => "Medline" ] ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Seasonal variation of skin resistance to irritants" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "T. Agner" 1 => "J. Serup" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1989" "volumen" => "121" "paginaInicial" => "323" "paginaFinal" => "328" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2803958" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of xerosis and ageing on epidermal proliferation and differentiation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Engelke" 1 => "J.M. Jensen" 2 => "S. Ekanayake-Mudiyanselage" 3 => "E. Proksch" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Br J Dermatol" "fecha" => "1997" "volumen" => "137" "paginaInicial" => "219" "paginaFinal" => "225" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9292070" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New perspectives on epidermal barrier dysfunction in atopic dermatitis: geneenvironment interactions" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.J. Cork" 1 => "D.A. Robinson" 2 => "Y. Vasilopoulos" 3 => "A. Ferguson" 4 => "M. Moustafa" 5 => "A. MacGowan" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaci.2006.04.042" "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "2006" "volumen" => "118" "paginaInicial" => "3" "paginaFinal" => "21" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16815133" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Y. Werner" 1 => "M. Lindberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Acta Derm Venereol" "fecha" => "1985" "volumen" => "65" "paginaInicial" => "102" "paginaFinal" => "105" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2408409" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673605678890" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evaluation of the hydration and water binding capacity in atopic skin and so-called dry skin" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P. Thune" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Derm Venereol" "fecha" => "1989" "volumen" => "144" "numero" => "Suppl" "paginaInicial" => "133" "paginaFinal" => "135" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "X-linked ichthyosis due to steroid sulphatase deficiency" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "L.J. Shapiro" 1 => "R Weiss" 2 => "Webster." 3 => "J.T. Frances" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1978" "volumen" => "1" "paginaInicial" => "70" "paginaFinal" => "72" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6140424" "web" => "Medline" ] ] ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cholesterol sulphate inhibits proteases that are involved in desquamation of stratum corneum" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Sato" 1 => "M. Denda" 2 => "J. Nakinishi" 3 => "J. Nomura" 4 => "J. Koyama" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1523-1747.1998.00244.x" "Revista" => array:6 [ "tituloSerie" => "J Invest Dermatol" "fecha" => "1998" "volumen" => "111" "paginaInicial" => "189" "paginaFinal" => "194" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9699715" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatitis de manos" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C. Ramírez" 1 => "S.E. Jacob" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2006" "volumen" => "97" "paginaInicial" => "363" "paginaFinal" => "373" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16956515" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.L. Chamlin" 1 => "J. Kao" 2 => "I.J. Freiden" 3 => "M.Y. Sheu" 4 => "A.J. Fowler" 5 => "J.W. Fluhr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "198" "paginaFinal" => "208" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12140465" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Glycerol replacement corrects defective skin hydration, elasticity and barrier function in aquaporin-3-deficient mice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Hara" 1 => "A.S. Verkman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1073/pnas.1230416100" "Revista" => array:6 [ "tituloSerie" => "PNAS" "fecha" => "2003" "volumen" => "100" "paginaInicial" => "7360" "paginaFinal" => "7365" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12771381" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Etude in vitro du pouvoir antiprurigineux du glycocolle: effet sur la dégranulation des mastocytes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Paubert-Braquet" 1 => "G. Lefrançois" 2 => "S. Picquot" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Thérapeutique" "fecha" => "1992" "volumen" => "95" "paginaInicial" => "2" "paginaFinal" => "3" ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Studies on wound healing: effects of calcium pantothenate on the migration, proliferation and protein synthesis of human dermal fibroblasts in culture" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "B.I. Weimann" 1 => "D. Hermann" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1024/0300-9831.69.2.113" "Revista" => array:6 [ "tituloSerie" => "Int J Vitam Nutr Res" "fecha" => "1999" "volumen" => "69" "paginaInicial" => "113" "paginaFinal" => "119" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10218148" "web" => "Medline" ] ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effects of pantothenic acid on fibroblastic cell cultures" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Lacroix" 1 => "E. Didier" 2 => "J.F. Grenier" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Res Exp Med" "fecha" => "1988" "volumen" => "188" "paginaInicial" => "391" "paginaFinal" => "396" ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of bepanthen ointment on the graft-donor site wound-healing model: double-blind biometrological and clinical study, with assessment by the patient versus the vehicle" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P. Girard" 1 => "A. Beraud" 2 => "C. Goujon" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Nouv Dermatol" "fecha" => "1998" "volumen" => "17" "paginaInicial" => "559" "paginaFinal" => "570" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000009900000009/v1_201304241441/S1578219008703433/v1_201304241441/en/main.assets" "Apartado" => array:4 [ "identificador" => "6224" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Review article" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000009900000009/v1_201304241441/S1578219008703433/v1_201304241441/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219008703433?idApp=UINPBA000044" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 2 | 6 | 8 |
2024 October | 74 | 73 | 147 |
2024 September | 73 | 56 | 129 |
2024 August | 95 | 99 | 194 |
2024 July | 79 | 80 | 159 |
2024 June | 69 | 84 | 153 |
2024 May | 65 | 52 | 117 |
2024 April | 60 | 32 | 92 |
2024 March | 82 | 55 | 137 |
2024 February | 56 | 48 | 104 |
2024 January | 65 | 73 | 138 |
2023 December | 68 | 53 | 121 |
2023 November | 64 | 47 | 111 |
2023 October | 60 | 56 | 116 |
2023 September | 59 | 49 | 108 |
2023 August | 42 | 29 | 71 |
2023 July | 79 | 75 | 154 |
2023 June | 63 | 27 | 90 |
2023 May | 44 | 33 | 77 |
2023 April | 44 | 28 | 72 |
2023 March | 30 | 45 | 75 |
2023 February | 24 | 41 | 65 |
2023 January | 31 | 44 | 75 |
2022 December | 30 | 50 | 80 |
2022 November | 19 | 36 | 55 |
2022 October | 13 | 40 | 53 |
2022 September | 14 | 57 | 71 |
2022 August | 16 | 49 | 65 |
2022 July | 15 | 88 | 103 |
2022 June | 37 | 46 | 83 |
2022 May | 56 | 61 | 117 |
2022 April | 62 | 63 | 125 |
2022 March | 37 | 51 | 88 |
2022 February | 54 | 30 | 84 |
2022 January | 31 | 49 | 80 |
2021 December | 38 | 69 | 107 |
2021 November | 49 | 58 | 107 |
2021 October | 46 | 55 | 101 |
2021 September | 38 | 50 | 88 |
2021 August | 39 | 47 | 86 |
2021 July | 35 | 42 | 77 |
2021 June | 37 | 40 | 77 |
2021 May | 35 | 37 | 72 |
2021 April | 44 | 80 | 124 |
2021 March | 85 | 73 | 158 |
2021 February | 86 | 56 | 142 |
2021 January | 40 | 42 | 82 |
2020 December | 62 | 38 | 100 |
2020 November | 29 | 29 | 58 |
2020 October | 46 | 20 | 66 |
2020 September | 39 | 17 | 56 |
2020 August | 32 | 78 | 110 |
2020 July | 37 | 35 | 72 |
2020 June | 31 | 28 | 59 |
2020 May | 25 | 35 | 60 |
2020 April | 26 | 31 | 57 |
2020 March | 19 | 32 | 51 |
2020 February | 3 | 23 | 26 |
2020 January | 3 | 11 | 14 |
2019 December | 0 | 32 | 32 |
2019 November | 0 | 32 | 32 |
2019 October | 0 | 37 | 37 |
2019 September | 0 | 35 | 35 |
2019 August | 0 | 17 | 17 |
2019 July | 0 | 28 | 28 |
2019 June | 0 | 21 | 21 |
2019 May | 1 | 129 | 130 |
2019 April | 0 | 79 | 79 |
2019 March | 0 | 18 | 18 |
2019 February | 0 | 32 | 32 |
2019 January | 1 | 26 | 27 |
2018 December | 1 | 10 | 11 |
2018 November | 0 | 3 | 3 |
2018 October | 0 | 1 | 1 |
2018 September | 1 | 13 | 14 |
2018 August | 0 | 27 | 27 |
2018 July | 0 | 21 | 21 |
2018 June | 0 | 26 | 26 |
2018 May | 0 | 10 | 10 |
2018 April | 0 | 23 | 23 |
2018 March | 0 | 40 | 40 |
2018 February | 16 | 46 | 62 |
2018 January | 14 | 29 | 43 |
2017 December | 21 | 42 | 63 |
2017 November | 25 | 67 | 92 |
2017 October | 18 | 53 | 71 |
2017 September | 21 | 51 | 72 |
2017 August | 27 | 44 | 71 |
2017 July | 20 | 63 | 83 |
2017 June | 33 | 69 | 102 |
2017 May | 35 | 48 | 83 |
2017 April | 35 | 81 | 116 |
2017 March | 45 | 90 | 135 |
2017 February | 24 | 96 | 120 |
2017 January | 31 | 98 | 129 |
2016 December | 31 | 55 | 86 |
2016 November | 27 | 76 | 103 |
2016 October | 29 | 122 | 151 |
2016 September | 42 | 90 | 132 |
2016 August | 56 | 48 | 104 |
2016 July | 35 | 37 | 72 |
2016 June | 12 | 35 | 47 |
2016 May | 5 | 24 | 29 |
2016 April | 6 | 17 | 23 |
2016 March | 3 | 1 | 4 |
2016 February | 5 | 13 | 18 |
2016 January | 6 | 13 | 19 |
2015 December | 13 | 15 | 28 |
2015 November | 19 | 17 | 36 |
2015 October | 6 | 14 | 20 |
2015 September | 7 | 1 | 8 |
2015 August | 13 | 10 | 23 |
2015 July | 35 | 65 | 100 |
2015 June | 42 | 42 | 84 |
2015 May | 63 | 45 | 108 |
2015 April | 45 | 49 | 94 |
2015 March | 39 | 42 | 81 |
2015 February | 30 | 48 | 78 |
2015 January | 37 | 54 | 91 |
2014 December | 28 | 40 | 68 |
2014 November | 30 | 35 | 65 |
2014 October | 31 | 38 | 69 |
2014 September | 29 | 32 | 61 |
2014 August | 34 | 31 | 65 |
2014 July | 48 | 33 | 81 |
2014 June | 49 | 16 | 65 |
2014 May | 38 | 18 | 56 |
2014 April | 35 | 13 | 48 |
2014 March | 45 | 55 | 100 |
2014 February | 40 | 49 | 89 |
2014 January | 50 | 44 | 94 |
2013 December | 38 | 39 | 77 |
2013 November | 34 | 67 | 101 |
2013 October | 37 | 48 | 85 |
2013 September | 34 | 52 | 86 |
2013 August | 33 | 88 | 121 |
2013 July | 20 | 106 | 126 |
2013 June | 19 | 102 | 121 |
2013 May | 54 | 81 | 135 |
2013 April | 22 | 78 | 100 |
2013 March | 28 | 73 | 101 |
2013 February | 32 | 27 | 59 |
2013 January | 20 | 10 | 30 |