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1</a>&#41;&#46; The patient referred pruritus and pain due to retraction at this site asking for therapy&#46; This scar scored 8 points in the Modified Vancouver Scar Scale &#40;mVSS&#41;&#46; The other lesions on the body left only post inflammatory hyperpigmentation at most&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Clinical course and treatment</span><p id="par0010" class="elsevierStylePara elsevierViewall">A combined laser therapy session was scheduled and performed around 5 months after resolution of the active lesions&#46; Anesthesia with lidocaine 4&#37; gel was used&#46; The patient underwent treatment with pulsed dye laser &#40;PDL&#41; &#8211; &#40;Candela&#39;s V-Beam Perfecta&#41; associated with 1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass &#40;Frax1550<span class="elsevierStyleHsp" style=""></span>nm by Candela&#41;&#44; parameterized 0&#46;45<span class="elsevierStyleHsp" style=""></span>ms 6<span class="elsevierStyleHsp" style=""></span>J 7<span class="elsevierStyleHsp" style=""></span>mm 1 pass &#40;PDL&#41; and 10<span class="elsevierStyleHsp" style=""></span>mm 3&#46;2<span class="elsevierStyleHsp" style=""></span>ms 40&#46;0<span class="elsevierStyleHsp" style=""></span>J 3 passes &#40;1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass&#41;&#44; both lasers used in the same session sequentially &#40;first PDL and ErbGlass after&#41;&#46; The treatment lasted 10<span class="elsevierStyleHsp" style=""></span>min and was well-tolerated by the patient&#46; The only side effects reported were pain 4&#47;10 on the moment of treatment and swelling that lasted less than 24<span class="elsevierStyleHsp" style=""></span>h&#44; managed with oral non-steroidal anti-inflammatory drugs&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Two months after the laser therapy&#44; the erythema and ulceration had disappeared&#44; leaving only a slight skin retraction in the scar location &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; with a mVSS score of 2&#46; The patient reported high levels of satisfaction with the cosmetic and functional results&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Comment</span><p id="par0020" class="elsevierStylePara elsevierViewall">Mpox skin lesions can cause scarring in up to 13&#37; of affected patients<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> and can lead to both atrophic and hyperpigmented scars&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> Scarring may cause functional impairment and cosmetic concerns&#44; which both may have an impact on physical and psychological health and social life &#40;considering the stigmatization and discrimination associated with Mpox infection&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">General recommendations for Mpox scar prevention exist&#44; such as skin washing with mild soap and water&#44; avoidance of scratching and unroofing of lesion and scabs&#44; sun protection and the use of silicone-based gels or sheeting&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> However&#44; the literature regarding genital scarring of any etiology and its treatment is scarce&#44; particularly in the case of Mpox scars&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">PDL use has shown results in scar treatment&#44; with improvement in erythema&#44; texture&#44; pliability and pain&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> It has also shown result in hypertrophic scarring&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> The combined treatment with PDL and 1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass has shown good results in traumatic scars&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a> However&#44; their use in Mpox scars has not been published yet&#46; By showing promising results in scar improvement&#44; cosmetic and functional results and patient satisfaction with minimal side effects&#44; this case report pretends to demonstrate the potential role of combined laser therapy in Mpox scars treatment&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest&#46;</p></span></span>"
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Case and Research Letter
Combined Laser Therapy in a Mpox Scar
Laserterapia Combinada en una cicatriz de Mpox
B. Pimentel
Corresponding author
pimentel233@gmail.com

Corresponding author.
, A. Palmeiro, G. Catorze
Serviço de Dermatologia do Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal
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1</a>&#41;&#46; The patient referred pruritus and pain due to retraction at this site asking for therapy&#46; This scar scored 8 points in the Modified Vancouver Scar Scale &#40;mVSS&#41;&#46; The other lesions on the body left only post inflammatory hyperpigmentation at most&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Clinical course and treatment</span><p id="par0010" class="elsevierStylePara elsevierViewall">A combined laser therapy session was scheduled and performed around 5 months after resolution of the active lesions&#46; Anesthesia with lidocaine 4&#37; gel was used&#46; The patient underwent treatment with pulsed dye laser &#40;PDL&#41; &#8211; &#40;Candela&#39;s V-Beam Perfecta&#41; associated with 1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass &#40;Frax1550<span class="elsevierStyleHsp" style=""></span>nm by Candela&#41;&#44; parameterized 0&#46;45<span class="elsevierStyleHsp" style=""></span>ms 6<span class="elsevierStyleHsp" style=""></span>J 7<span class="elsevierStyleHsp" style=""></span>mm 1 pass &#40;PDL&#41; and 10<span class="elsevierStyleHsp" style=""></span>mm 3&#46;2<span class="elsevierStyleHsp" style=""></span>ms 40&#46;0<span class="elsevierStyleHsp" style=""></span>J 3 passes &#40;1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass&#41;&#44; both lasers used in the same session sequentially &#40;first PDL and ErbGlass after&#41;&#46; The treatment lasted 10<span class="elsevierStyleHsp" style=""></span>min and was well-tolerated by the patient&#46; The only side effects reported were pain 4&#47;10 on the moment of treatment and swelling that lasted less than 24<span class="elsevierStyleHsp" style=""></span>h&#44; managed with oral non-steroidal anti-inflammatory drugs&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">Two months after the laser therapy&#44; the erythema and ulceration had disappeared&#44; leaving only a slight skin retraction in the scar location &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; with a mVSS score of 2&#46; The patient reported high levels of satisfaction with the cosmetic and functional results&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Comment</span><p id="par0020" class="elsevierStylePara elsevierViewall">Mpox skin lesions can cause scarring in up to 13&#37; of affected patients<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> and can lead to both atrophic and hyperpigmented scars&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> Scarring may cause functional impairment and cosmetic concerns&#44; which both may have an impact on physical and psychological health and social life &#40;considering the stigmatization and discrimination associated with Mpox infection&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">General recommendations for Mpox scar prevention exist&#44; such as skin washing with mild soap and water&#44; avoidance of scratching and unroofing of lesion and scabs&#44; sun protection and the use of silicone-based gels or sheeting&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> However&#44; the literature regarding genital scarring of any etiology and its treatment is scarce&#44; particularly in the case of Mpox scars&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">PDL use has shown results in scar treatment&#44; with improvement in erythema&#44; texture&#44; pliability and pain&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> It has also shown result in hypertrophic scarring&#46;<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> The combined treatment with PDL and 1550<span class="elsevierStyleHsp" style=""></span>nm ErbGlass has shown good results in traumatic scars&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a> However&#44; their use in Mpox scars has not been published yet&#46; By showing promising results in scar improvement&#44; cosmetic and functional results and patient satisfaction with minimal side effects&#44; this case report pretends to demonstrate the potential role of combined laser therapy in Mpox scars treatment&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conflict of interest</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflict of interest&#46;</p></span></span>"
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