Letter to the Editor
Treatments for Monkeypox
Tratamientos para la viruela del mono
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Sookaromdee, V. Wiwanitkit" "autores" => array:2 [ 0 => array:2 [ "nombre" => "P." "apellidos" => "Sookaromdee" ] 1 => array:2 [ "nombre" => "V." "apellidos" => "Wiwanitkit" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731022009425?idApp=UINPBA000044" "url" => "/00017310/0000011400000001/v1_202301060625/S0001731022009425/v1_202301060625/es/main.assets" ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Treatments for Monkeypox" "tieneTextoCompleto" => true "saludo" => "<span class="elsevierStyleItalic">To the Editor,</span>" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "94" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "P. Sookaromdee, V. Wiwanitkit" "autores" => array:2 [ 0 => array:4 [ "nombre" => "P." "apellidos" => "Sookaromdee" "email" => array:1 [ 0 => "pathumsook@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "V." "apellidos" => "Wiwanitkit" "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">d</span>" "identificador" => "aff0020" ] ] ] ] "afiliaciones" => array:4 [ 0 => array:3 [ "entidad" => "Private Academic Consultant, Bangkok, Thailand" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Joseph Ayobaalola University, Ikeji-Arakeji, Nigeria" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Dr DY Patil University, Pune, India" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Faculty of Medicine, University of Nis, Serbia" "etiqueta" => "d" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tratamientos para la viruela del mono" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We would like to share ideas on the publication “Potential Treatments for Monkeypox.”<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> According to Rodrguez-Cuadrado et al., tecovirimat, an antiviral that blocks the VP37 protein found on the surface of orthopoxviruses, is the only medication currently licensed for the treatment of MPX (EMA). Its effectiveness and good safety profile, with the most common side effects being headache and nausea, led Cuadrado et al. to approve it “under extraordinary conditions”.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> In addition to the well-known pox infections, new zoonotic pox diseases have emerged as a severe concern in infectious medicine.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> Europe is now experiencing a significant public health hazard due to the spread of monkey pox.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> Due to zoonosis, the unusual pox infection known as monkey pox has returned.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> Many parts of the world are now experiencing a significant public health threat from monkey pox.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">The best way to cure monkeypox is yet unknown. Rodrguez-Cuadrado et al. brought out tecovirimat's potential benefit. This medication is rarely used in Africa, where it is endemic, and the patient's recovery could take place naturally. In addition to covirimat, the immune globulin intravenous may be another possibility that has to be thoroughly researched.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> There are few details available about covirimat's safety. In a prior UK study, tecovirimat had no adverse effects while brincidofovir did, but the sample size was too small to draw any firm conclusions.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> A report from the USA on the safe use of tecovirimat to a patient is also available.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a> The moment has come for more data collection due to the limited reports. Because of the scarcity of reports, it is now necessary to collect more data and conduct post-approval monitoring of the efficacy and safety of tecovirimat for the treatment of monkeypox.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of Interest</span><p id="par0015" class="elsevierStylePara elsevierViewall">None declared.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Funding</span><p id="par0020" class="elsevierStylePara elsevierViewall">None declared.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflict of Interest" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Funding" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Potential treatments for monkeypox" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "F.J. Rodríguez-Cuadrado" 1 => "E.L. Pinto-Pulido" 2 => "M. Fernández-Parrado" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2022.06.013" "Revista" => array:2 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2022" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical zoonotic pox: acute merging illness that can be easily forgotten" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "S. Wiwanitkit" 1 => "V. Wiwanitkit" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Acute Dis" "fecha" => "2018" "volumen" => "7" "paginaInicial" => "88" "paginaFinal" => "89" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0045" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Re-emerging monkeypox: an old disease to be monitored" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "V. Mungmunpuntipantip" 1 => "V. Wiwanitkit" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:2 [ "tituloSerie" => "BMJ Rapid Response" "fecha" => "2022" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0050" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Prevention and treatment of monkeypox" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.G. Rizk" 1 => "G. Lippi" 2 => "B.M. Henry" 3 => "D.N. Forthal" 4 => "Y. Rizk" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s40265-022-01742-y" "Revista" => array:5 [ "tituloSerie" => "Drugs" "fecha" => "2022" "paginaInicial" => "1" "paginaFinal" => "7" "itemHostRev" => array:3 [ "pii" => "S0923753419373120" "estado" => "S300" "issn" => "09237534" ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0055" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical features and management of human monkeypox: a retrospective observational study in the UK" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "H. Adler" 1 => "S. Gould" 2 => "P. Hine" 3 => "L.B. Snell" 4 => "W. Wong" 5 => "C.F. Houlihan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Lancet Infect Dis" "fecha" => "2022" "itemHostRev" => array:3 [ "pii" => "S0923753419313705" "estado" => "S300" "issn" => "09237534" ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0060" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Monkeypox in a traveler returning from Nigeria – Dallas, Texas, July 2021" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.K. Rao" 1 => "J. Schulte" 2 => "T.H. Chen" 3 => "C.M. Hughes" 4 => "W. Davidson" 5 => "J.M. Neff" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.15585/mmwr.mm7114a1" "Revista" => array:6 [ "tituloSerie" => "MMWR Morb Mortal Wkly Rep" "fecha" => "2022" "volumen" => "71" "paginaInicial" => "509" "paginaFinal" => "516" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35389974" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00017310/0000011400000001/v1_202301060625/S0001731022007694/v1_202301060625/en/main.assets" "Apartado" => array:4 [ "identificador" => "6165" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Cartas al Director" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000011400000001/v1_202301060625/S0001731022007694/v1_202301060625/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731022007694?idApp=UINPBA000044" ]
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