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Parodi" "autores" => array:4 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Herzum" "email" => array:1 [ 0 => "astridherzum@yahoo.it" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Burlando" ] 2 => array:2 [ "nombre" => "C." "apellidos" => "Micalizzi" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Parodi" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "DISSAL, Section of Dermatology, University of Genoa, Ospedale Policlinico San Martino IRCCS, Genova, Italy" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Condiloma lata y erupción papular de sífilis secundaria" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 567 "Ancho" => 1005 "Tamanyo" => 86930 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 41-year-old-man presented with a 2-month history of painful perianal lesions and various maculo-papular lesions that occurred simultaneously on his lower limbs.</p><p id="par0010" class="elsevierStylePara elsevierViewall">He reported generalized fatigue and previous unprotected homosexual intercourse.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Physical examination evidenced moist-to-macerated, flat-topped, tumor-like nodules around the anus, surrounded by erythemato-squamous annular patches and scattered papules (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">On the legs and soles, coppery-shaded erythemato-squamous, nummular plaques and papules were noted, some of which with a collarette of scale (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B).</p><p id="par0025" class="elsevierStylePara elsevierViewall">The clinical presentation of these lesion was highly suggestive for condylomata lata (CL) and for secondary syphilis papular squamous rash.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Positive TPHA and VDRL confirmed the clinical suspect of secondary syphilis. The patient was treated with long-acting Benzathine G-penicillin (2.4<span class="elsevierStyleHsp" style=""></span>MU intramuscularly).</p><p id="par0035" class="elsevierStylePara elsevierViewall">Secondary syphilis is polymorphic, causing initial maculo-papular rush, followed by persistent erythemato-papulo-squamous lesions, as on our patient's legs, soles and perineum.<span class="elsevierStyleSup">1</span> Also, 6–23% present CL: vegetating, flat-topped, infectious lesions, painful when macerated by friction, which also perpetuates dissemination.</p><p id="par0040" class="elsevierStylePara elsevierViewall">Dermatologists play a key role in identifying and treating syphilis. 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