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Ferreira, L. Soares-de-Almeida, P. Filipe" "autores" => array:4 [ 0 => array:4 [ "nombre" => "C." "apellidos" => "Correia" "email" => array:1 [ 0 => "catarinacorreia03@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J." "apellidos" => "Ferreira" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "L." "apellidos" => "Soares-de-Almeida" "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "P." "apellidos" => "Filipe" "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Dermatology Department, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Dermatology Research Unit, Instituto de Medicina Molecular, Universidade de Lisboa, Lisbon, Portugal" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Dermatology Universitary Clinic, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Una causa inusual de eumicetoma – <span class="elsevierStyleItalic">Fusarium solani keratoplasticum</span>" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 586 "Ancho" => 1255 "Tamanyo" => 160667 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 35-year-old man from São Tomé e Príncipe presented with a 12-year history of a slowly progressive left foot mass. Physical examination displayed an extensive unpainful and well-defined mass in his left ankle's posterolateral side. The lesion had multiple red, subcutaneous nodules with draining sinus tracts and grain discharge (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). Magnetic resonance imaging did not reveal osteomyelitis (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). A skin biopsy revealed granules in suppuration areas surrounded by eosinophilic material (Splendore-Hoeppli phenomenon) (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C). Direct examination of the sinuses discharge showed multiple white grains with thin, septate hyphae (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D). Microscopic examination of cultures revealed short conidiophores with macro-and microconidia (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>E). These findings support the diagnosis of white grain eumycetoma. The causative agent identified by polymerase chain reaction and DNA sequencing was <span class="elsevierStyleItalic">Fusarium solani var keratoplasticum</span>. The patient was treated with 400<span class="elsevierStyleHsp" style=""></span>mg daily oral itraconazole for 24 months, with no response. Therapy was changed to 400<span class="elsevierStyleHsp" style=""></span>mg daily oral voriconazole for 12 months, and he was referred to concomitant surgical excision. Eumycetoma, a neglected tropical disease, is a chronic and slowly progressive subcutaneous infection caused by several hyaline and dematiaceous fungi types. However, the genus <span class="elsevierStyleItalic">Fusarium</span> is a rare cause of mycetoma. Early recognition and treatment of this entity are essential.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 586 "Ancho" => 1255 "Tamanyo" => 160667 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00017310/0000011300000009/v1_202210040811/S0001731022002629/v1_202210040811/en/main.assets" "Apartado" => array:4 [ "identificador" => "83194" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Imágenes en Dermatología" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000011300000009/v1_202210040811/S0001731022002629/v1_202210040811/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731022002629?idApp=UINPBA000044" ]
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