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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>2&#46;789&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">60&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">A &#40;Atopy&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">238&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">714&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">L &#40;Leg&#41;<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">a</span></a>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">174&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Bater&#237;a&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">N&#250;mero de pacientes&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Est&#225;ndar&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">100&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
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                  \t\t\t\t">Dental&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">35&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">52&#44;23&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Metal&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">30&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">44&#44;78&#37;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
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                  \t\t\t\t">Panader&#237;a&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">16&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">23&#44;88&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Productos propios&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;45&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Cosm&#233;ticos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">1&#44;49&#37;&nbsp;\t\t\t\t\t\t\n
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    ]
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          "identificador" => "bibs0015"
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                  "contribucion" => array:1 [
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                      "titulo" => "Clinically relevant patch test results in patients with burning mouth syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
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                          "autores" => array:6 [
                            0 => "J&#46;C&#46; Steele"
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                            2 => "M&#46;D&#46;P&#46; Davis"
                            3 => "R&#46;R&#46; Torgerson"
                            4 => "L&#46;A&#46; Drage"
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                        "tituloSerie" => "Dermatitis"
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                        "paginaFinal" => "71"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22653121"
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                      "titulo" => "Burning mouth syndrome&#58; Patch test results from a large case series"
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                          "autores" => array:3 [
                            0 => "C&#46;B&#46; Lynde"
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                            2 => "S&#46;R&#46; Walsh"
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                    0 => array:2 [
                      "doi" => "10.2310/7750.2013.13096"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Cutan Med Surg"
                        "fecha" => "2014"
                        "volumen" => "18"
                        "paginaInicial" => "174"
                        "paginaFinal" => "179"
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                          "autores" => array:4 [
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                            2 => "L&#46; Pignataro"
                            3 => "F&#46; Spadari"
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                  "host" => array:1 [
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                      "doi" => "10.1111/j.1601-0825.2009.01515.x"
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                        "tituloSerie" => "Oral Dis"
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                        "paginaInicial" => "255"
                        "paginaFinal" => "258"
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Carta científico-clínica
¿Suelen ser relevantes las pruebas epicutáneas en el paciente con síndrome de boca urente?
Are Patch Test Results Usually Relevant in Patients With Burning Mouth Syndrome?
F.J. De la Torre Gomar
Corresponding author
fjtogo@gmail.com

Autor para correspondencia.
, S. Heras González, R. González Pérez
Servicio de Dermatología, Hospital Universitario Araba, Vitoria-Gasteiz, España
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pero las positividades m&#225;s frecuentes corresponden a los metales&#44; especialmente el n&#237;quel&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Teniendo en cuenta lo indicado&#44; realizamos un estudio observacional retrospectivo con el objetivo de determinar la relevancia cl&#237;nica de las positividades halladas en pacientes con SBU&#46; Para ello se analizaron los resultados de las pruebas epicut&#225;neas realizadas a pacientes con este diagn&#243;stico remitidos a nuestra unidad de alergia cut&#225;nea durante un periodo de tiempo de 15<span class="elsevierStyleHsp" style=""></span>a&#241;os &#40;enero de 2001 a diciembre de 2015&#41; y se realiz&#243; un seguimiento de estos a trav&#233;s de historia cl&#237;nica digital &#40;Osabide global&#41; para establecer la relevancia de las positividades&#46; Durante este periodo de tiempo se parchearon un total de 2&#46;789 pacientes&#44; de los cuales 67 consultaron por SBU &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46; Para describir la caracterizaci&#243;n de la cohorte estudiada se utiliz&#243; el &#237;ndice MOAHLFA &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">tabla 1</a>&#41;&#46; Todos los pacientes con SBU fueron parcheados con la serie est&#225;ndar del Grupo Espa&#241;ol de Investigaci&#243;n en Dermatitis de Contacto y Alergia Cut&#225;nea &#40;GEIDAC&#41; y en 65 de ellos se coloc&#243;&#44; seg&#250;n orientara la historia cl&#237;nica&#44; adem&#225;s alguna serie suplementaria&#44; siendo las m&#225;s utilizadas una serie dental &#40;Chemotecnique&#44; Suecia&#41; &#40;52&#44;23&#37;&#41; y una serie de metales &#40;Chemotecnique&#44; Suecia&#41; &#40;44&#44;7&#37;&#41; &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">tabla 2</a>&#41;&#46; Las lecturas se efectuaron a las 48 y a las 96<span class="elsevierStyleHsp" style=""></span>h&#44; siguiendo las recomendaciones de la <span class="elsevierStyleItalic">European Society of Contact Dermatitis</span> &#40;ESCD&#41;&#46; En 23 &#40;34&#44;3&#37;&#41; de los 67 pacientes se observ&#243; alguna reacci&#243;n al&#233;rgica&#44; registr&#225;ndose un total de 32 positividades&#46; El n&#237;quel &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>11&#41; fue el principal al&#233;rgeno&#44; seguido de metilisotiazolinona&#47;metilcloroisotiazolinona &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41; y berilio &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#41;&#46; Solo en 2 &#40;2&#44;9&#37;&#41; de los 67 pacientes con SBU pudimos establecer una relevancia presente de las positividades&#46; Ambos casos correspondieron a pacientes sensibilizados al n&#237;quel que portaban pr&#243;tesis dentales met&#225;licas&#44; remitiendo la sintomatolog&#237;a al retirar dichas pr&#243;tesis en cuya composici&#243;n figuraba dicho metal&#46; En los 21 pacientes restantes con pruebas positivas&#44; estas se consideraron no relevantes o de relevancia desconocida por diversos motivos&#44; principalmente por evidenciarse en ellos positividades a metales que no formaban parte de la composici&#243;n de las pr&#243;tesis dentales que portaban en ese momento &#40;<a class="elsevierStyleCrossRef" href="#fig0005">fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">En nuestra cohorte de pacientes solo el 2&#44;9&#37; de las positividades se consideraron cl&#237;nicamente relevantes o con relevancia presente&#44; porcentaje claramente inferior a los reflejados en la literatura<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">1-3</span></a>&#46; Estas relevancias presentes correspondieron al n&#237;quel&#44; un al&#233;rgeno que forma parte de la serie est&#225;ndar del GEIDAC&#46; Por tanto&#44; las series suplementarias empleadas no conllevaron un incremento en el n&#250;mero de positividades cl&#237;nicamente relevantes diagnosticadas&#46; En funci&#243;n de estos resultados&#44; creemos que&#44; a excepci&#243;n de casos seleccionados en los que la historia cl&#237;nica oriente hacia un origen al&#233;rgico de la sintomatolog&#237;a&#44; las pruebas epicut&#225;neas no deber&#237;an incluirse entre los estudios a realizar rutinariamente en los pacientes con SBU&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicto de intereses</span><p id="par0020" class="elsevierStylePara elsevierViewall">Los autores declaran no tener ning&#250;n conflicto de intereses&#46;</p></span></span>"
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                  \t\t\t\t">44&#44;78&#37;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Cosm&#233;ticos&nbsp;\t\t\t\t\t\t\n
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Article information
ISSN: 00017310
Original language: Spanish
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Idiomas
Actas Dermo-Sifiliográficas
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