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El examen mostró una úlcera irregular de 25<span class="elsevierStyleHsp" style=""></span>cm de diámetro que se extendía desde la línea capilar frontal hacia la región occipital, con lesiones de aspecto tumoral, áreas hiperqueratósicas necróticas y bordes de tipo infiltrante que sangraban al tacto (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>). La calota craneal estaba expuesta con una destrucción de hueso parietal y exposición meníngea. Las biopsias confirmaron el diagnóstico de carcinoma escamoso infiltrante. Una TAC mostró la ausencia de adenopatías y metástasis a distancia. La resonancia magnética cerebral mostró osteonecrosis e infiltración de la paquimeninge, sin afectación parenquimatosa (<a class="elsevierStyleCrossRef" href="#fig0010">fig. 2</a>). Dada su hepatopatía, se inició el tratamiento con cisplatino y radioterapia externa concomitante, durante la cual presentó un ictus con hemiplejía derecha. La resonancia magnética nuclear de control mostró progresión e infiltración cerebral. La paciente falleció a los 6 meses del diagnóstico.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">El carcinoma escamoso es el segundo tipo de cáncer cutáneo no melanoma más común en pacientes caucásicos, generalmente localizado en áreas de exposición crónica a la luz ultravioleta. Las neoplasias cutáneas asociadas a inmunosupresión presentan una mayor agresividad, unas mayores tasas de recurrencia y riesgo de metástasis en el momento del diagnóstico. Su incidencia aumenta años después de realizarse un trasplante de órganos.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 431 "Ancho" => 905 "Tamanyo" => 108675 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 732 "Ancho" => 755 "Tamanyo" => 47536 ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00017310/0000011200000002/v1_202102020721/S0001731020301757/v1_202102020721/es/main.assets" "Apartado" => array:4 [ "identificador" => "41021" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes en Dermatología" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000011200000002/v1_202102020721/S0001731020301757/v1_202102020721/es/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020301757?idApp=UINPBA000044" ]
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