Manejo del paciente con hidradenitis supurativa
Management of patients with hidradenitis suppurativa
A. Martorella,
, A. Caballerob, Y. González Lamac, D. Jiménez-Gallod, M. Lázaro Serranoe, J. Mirandab, J.C. Pascualf, L. Salgado-Boqueteg, I. Marín-Jiménezb
Corresponding author
a Servicio de Dermatología, Hospital de Manises, Valencia, España
b Servicio de Gastroenterología, Hospital General Universitario Gregorio Marañón, Madrid, España
c Unidad de Enfermedad Inflamatoria Intestinal, Servicio de Aparato Digestivo, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España
d Unidad de Gestión Clínica de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario Puerta del Mar, Servicio Andaluz de Salud, Cádiz, España
e Servicio de Dermatología, Hospital Universitario Basurto, Bilbao, España
f Servicio de Dermatología, Hospital General de Alicante, Alicante, España
g Servicio de Dermatología, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, España
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Su tratamiento comprende un abordaje médico y quirúrgico. El tratamiento médico se basa en el uso de antibióticos, retinoides y fármacos antiinflamatorios, donde la terapia biológica anti-TNFα (infliximab y adalimumab) ocupa el papel central en el tratamiento de la hidradenitis supurativa moderada-grave con el mayor grado de evidencia científica. Actualmente, adalimumab es el único fármaco indicado en ficha técnica para el tratamiento de esta patología. Debido a los pocos ensayos clínicos terapéuticos en hidradenitis supurativa, todavía no existe una guía terapéutica con evidencia sólida, y la mayoría de fármacos tienen un nivel de evidencia bajo. Sin embargo, el tratamiento precoz en pacientes con hidradenitis supurativa, probablemente pueda disminuir las complicaciones derivadas de esta. En esta revisión se analizan los diferentes tratamientos utilizados en esta enfermedad dermatológica y se aporta un algoritmo terapéutico con diferentes opciones de tratamiento.</p></span>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a high prevalence in the population. Treatment options are both medical and surgical. Medical treatment is based on the use of antibiotics, retinoids, and anti-inflammatory drugs, in which anti-TNFα agents (infliximab y adalimumab) play a central role in the treatment of moderate-to-severe HS and enjoy the highest level of scientific support. Currently, adalimumab is the only drug approved in the summary of product characteristics for the treatment of this disease. Due to the scarcity of clinical trials in HS, there is still no therapeutic guideline backed by solid evidence and the evidence for most drugs is low. However, early treatment in patients with HS would probably reduce the complications of this disease. This review analyses the distinct treatments used in this dermatological disease and provides a therapeutic algorithm with different treatment options.</p></span>" ] ] ] "idiomaDefecto" => "es" "url" => "/00017310/00000107000000S2/v1_201701100052/S0001731017300078/v1_201701100052/es/main.assets" "Apartado" => null "PDF" => "https://static.elsevier.es/multimedia/00017310/00000107000000S2/v1_201701100052/S0001731017300078/v1_201701100052/es/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731017300078?idApp=UINPBA000044" ]
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