Acute Postinfectious Pityriasis Rubra Pilaris: A Superantigenmediated Dermatosis

Ferrándiz-Pulido, C.; Bartralot, R.; Bassas, P.; Bodet, D.; Repiso, T.; Aparicio, G.; Mollet, J.; Serra, M.; García-Patos, V.

doi:10.1016/S1578-2190(09)70153-2

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"apellidos" => "Bartralot" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Bassas" ] 3 => array:2 [ "nombre" => "D." "apellidos" => "Bodet" ] 4 => array:2 [ "nombre" => "T." "apellidos" => "Repiso" ] 5 => array:2 [ "nombre" => "G." "apellidos" => "Aparicio" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "Mollet" ] 7 => array:2 [ "nombre" => "M." "apellidos" => "Serra" ] 8 => array:2 [ "nombre" => "V." "apellidos" => "García-Patos" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospital Vall d’Hebron, Universidad Autónoma de Barcelona, Barcelona, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Hospital Vall d’Hebron, Paseo Vall d’Hebron, 119-129, 08035 Barcelona, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Pitiriasis Rubra Pilaris Aguda Postinfecciosa: Una Dermatosis Mediada por Superantígenos" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2009-01-23" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84571" "palabras" => array:6 [ 0 => "pityriasis rubra pilaris" 1 => "erythroderma" 2 => "infection" 3 => "childhood" 4 => "juvenile" 5 => "superantigens" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84572" "palabras" => array:6 [ 0 => "pitiriasis rubra pilaris" 1 => "eritrodermia" 2 => "infección" 3 => "infantil" 4 => "juvenil" 5 => "superantígenos" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "Acute postinfectious pityriasis rubra pilaris (PRP) is a variant of juvenile PRP (Griffiths type III) characterized by no family history, an acute course associated with a prior fever, and good prognosis. Clinical features may resemble other superantigen-mediated diseases, such as scarlatiniform rash or staphylococcal scalded skin syndrome, but its histology and treatment are different. We present 4 cases of acute postinfectious PRP that illustrate the clinical features of this uncommon disease and we review possible underlying pathogenic mechanisms." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "La pitiriasis rubra pilaris (PRP) aguda postinfecciosa es una variante de la forma juvenil de PRP (tipo III de Griffiths) caracterizada por la ausencia de antecedentes familiares, curso agudo relacionado con un episodio febril previo y buen pronóstico. Clínicamente puede simular otras enfermedades mediadas por superantígenos, como los exantemas escarlatiniformes o el síndrome de la escaldadura estafilocócica; sin embargo, su histología y tratamiento son distintos. Presentamos 4 casos de PRP aguda postinfecciosa que ilustran las características clínicas de este proceso infrecuente y revisamos los posibles mecanismos fisiopatogénicos subyacentes." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "(Juvenile) Pityriasis rubra pilaris" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "V.N. Sehgal" 1 => "G. 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Abstract

Acute postinfectious pityriasis rubra pilaris (PRP) is a variant of juvenile PRP (Griffiths type III) characterized by no family history, an acute course associated with a prior fever, and good prognosis. Clinical features may resemble other superantigen-mediated diseases, such as scarlatiniform rash or staphylococcal scalded skin syndrome, but its histology and treatment are different. We present 4 cases of acute postinfectious PRP that illustrate the clinical features of this uncommon disease and we review possible underlying pathogenic mechanisms.

Key words:

pityriasis rubra pilaris

erythroderma

infection

childhood

juvenile

superantigens

Resumen

La pitiriasis rubra pilaris (PRP) aguda postinfecciosa es una variante de la forma juvenil de PRP (tipo III de Griffiths) caracterizada por la ausencia de antecedentes familiares, curso agudo relacionado con un episodio febril previo y buen pronóstico. Clínicamente puede simular otras enfermedades mediadas por superantígenos, como los exantemas escarlatiniformes o el síndrome de la escaldadura estafilocócica; sin embargo, su histología y tratamiento son distintos. Presentamos 4 casos de PRP aguda postinfecciosa que ilustran las características clínicas de este proceso infrecuente y revisamos los posibles mecanismos fisiopatogénicos subyacentes.

Palabras clave:

pitiriasis rubra pilaris

eritrodermia

infección

infantil

juvenil

superantígenos

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