Lichen sclerosus (LS), formerly called lichen sclerosus et atrophicus, is a chronic inflammatory disease of the skin, characterized by the presence of papules or atrophic, white plaques of unknown etiology, which primarily affects post-menopausal women. Prevalence in the general population is estimated at 1 of every 300-1000 individuals. There may be extragenital lesions, but most appear in the genital area. Cases of LS coexisting with lichen planus and morphea lesions have been repeatedly described, with both at the same time, and even with systemic scleroderma. Two thirds of the cases in children experience improvement or a cure with the onset of menarche, while adult forms tend to chronicity, with periods of exacerbation and remission; it may progress to spindle-cell carcinoma. Strong topical corticosteroids have proven to be the most effective treatment.
liquen escleroso y atrófico, morfea, genitales
lichen sclerosus et atrophicus, morphea, genitals
Actas Dermosifiliogr 2003;94:633-41 - Vol. 94 Núm.10