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Vol. 109. Num. 1.January - February 2018
Pages e1-e6Pages 1-94
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Vol. 109. Num. 1.January - February 2018
Pages e1-e6Pages 1-94
e-Case Report
DOI: 10.1016/j.adengl.2017.11.007
Intralymphatic Histiocytosis: A Report of 2 Cases
Histiocitosis intralinfática, a propósito de 2 casos
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M.E. Gómez-Sáncheza,
Corresponding author
m_gomsanchez@hotmail.com

Corresponding author.
, J.M. Azaña-Defezb, M.L. Martínez-Martíneza, M.T. López-Villaescusac
a Servicio de Dermatología, Hospital General de Villarrobledo, Villarrobledo, Albacete, Spain
b Servicio de Dermatología, Hospital General de Albacete, Albacete, Spain
c Servicio de Dermatología, Hospital General de Almansa, Almansa, Albacete, Spain
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Abstract

Intralymphatic histiocytosis is a benign condition characterized by poorly defined erythematous plaques (sometimes forming a reticular pattern) as well as the presence of nodules and vesicles. Its etiology and pathogenesis appear to be related to chronic inflammation in the affected area, prior surgery, or systemic disease, particularly rheumatoid arthritis. We report on 2 new cases, both associated with joint surgery in the affected area and osteoarticular disease (primary synovial osteochondromatosis and rheumatoid arthritis). This is a chronic disease and there is no specific treatment. Different treatment options were chosen in the 2 cases described. A spectacular response to treatment with oral pentoxifylline and topical tacrolimus was observed in 1 of the patients.

Keywords:
Intralymphatic histiocytosis
Reactive cutaneous angiomatosis
Rheumatoid arthritis
Treatment
Resumen

La histiocitosis intralinfática es un proceso benigno caracterizado por placas eritematosas mal delimitadas, a veces reticuladas, otras con nódulos o vesículas en su interior. Su etiopatogenia parece estar relacionada con procesos inflamatorios crónicos en el área afectada, cirugía previa o con enfermedades sistémicas, sobre todo con la artritis reumatoide. Presentamos 2 nuevos casos, ambos asociados a cirugía articular del área afecta y enfermedad osteoarticular (osteocondromatosis sinovial primaria y artritis reumatoide). Esta entidad tiene un comportamiento crónico y no existe un tratamiento específico. En los 2 casos presentados se plantearon distintas opciones terapéuticas, mostrando uno de ellos una respuesta espectacular al tratamiento con pentoxifilina oral junto con tacrolimus tópico.

Palabras clave:
Histiocitosis intralinfática
Angiomatosis cutánea reactiva
Artritis reumatoide
Tratamiento

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