The 3 Cs of melanoma: Time for a change?

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Cited by (18)

  • Biopsy of the pigmented lesion-When and how

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    Clinical examination and dermatoscopy (epiluminescence microscopy, skin surface microscopy, and dermatoscopy) are currently the two widely utilized modalities for examination of pigmented lesions. Clinical examination utilizing various mnemonics have existed over the years, including the three C's (color, contour, and change), the ABCD rule (asymmetry, border, color, diameter), and recently the longer mnemonic ABCDE with “E” indicating evolution.17-21 Evolution is especially important in patients who are elderly as a changing lesion within an elderly patient is more likely to be melanoma than in a young patient.22

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