Original articleThe dermoscopic inverse approach significantly improves the accuracy of human readers for lentigo maligna diagnosis
Section snippets
Methods
This diagnostic study was held during a 3-day dermoscopy masterclass, using a data set of facial pigmented macules, histopathologically diagnosed as LM, PAK, or SL/SK. The participants were asked to classify the lesions at 3 different timepoints, using a voting system with manual devices. One screen was placed in front of every 3 participants, and a video wall projection was visible to all of them. The study was conducted by using appropriately anonymized data sets and, therefore, ethics
Results
The male-to-female ratio of the 78 participants was 1:3.4, and the mean age was 41.1 years, ranging from 24 to 74 years. The main results are shown in Table II.
Discussion
Our study shows that the inverse approach significantly improves the ability of clinicians to accurately classify flat pigmented facial lesions. The improvement is most pronounced in the sensitivity for LM, which is the most relevant diagnostic measure from an outcome perspective. Although our study was not conducted in a clinical setting, the remarkable improvement in all diagnostic measures strongly suggests that the application of the inverse approach could significantly facilitate the
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Funding sources: None.
Conflicts of interest: None disclosed.
IRB approval status: Not applicable.
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