Journal of the American Academy of Dermatology
Continuing medical educationDiet in dermatology: Part I. Atopic dermatitis, acne, and nonmelanoma skin cancer
Section snippets
Atopic dermatitis
Key points Prenatal followed by postnatal probiotic supplementation decreases the risk of atopic dermatitis Postnatal prebiotic supplementation decreases the risk of atopic dermatitis Elimination diets are only appropriate for patients who have a food allergy that has been proven by oral food challenge Maternal allergen avoidance diets do not prevent atopic dermatitis Exclusive breastfeeding and supplementation with hydrolyzed formula is protective against atopic dermatitis for high-risk infants For infants at
Acne
Key points Multiple randomized controlled trials with biochemical and histopathologic evidence support the benefit of a low glycemic index/load diet for acne patients While observational studies suggest that frequent milk consumption imparts a higher risk of acne, randomized controlled trials are necessary before dietary recommendations can be made
Many patients believe that diet contributes to acne.28, 29, 30, 31, 32, 33 The relationship between diet and acne has emerged as a hot topic, with >10 reviews
Nonmelanoma skin cancer
Key points A large randomized controlled trial found no significant effect of a low-fat diet on nonmelanoma skin cancer; therefore, a fat restricted diet should not be recommended for nonmelanoma skin cancer prevention Selenium supplementation may increase the risk of squamous cell carcinoma and total nonmelanoma skin cancer and should be avoided The effect of retinol and retinoid supplementation on nonmelanoma skin cancer varies based on risk factors, comorbidities, and cancer type
References (138)
- et al.
Vitamin D effect in atopic dermatitis
J Am Acad Dermatol
(2013) - et al.
Breastfeeding and the onset of atopic dermatitis in childhood: a systematic review and meta-analysis of prospective studies
J Am Acad Dermatol
(2001) - et al.
Effect of breastfeeding on the development of atopic dermatitis during the first 3 years of life: results from the GINI-birth cohort study
J Pediatr
(2004) - et al.
The effect of hydrolyzed cow's milk formula for allergy prevention in the first year of life: the German Infant Nutritional Intervention Study, a randomized double-blind trial
J Allergy Clin Immunol
(2003) - et al.
Breast-feeding reduces the risk for childhood eczema
J Allergy Clin Immunol
(2005) - et al.
Beliefs and perceptions of patients with acne
J Am Acad Dermatol
(2001) - et al.
Relationships of self-reported dietary factors and perceived acne severity in a cohort of New York young adults
J Acad Nutr Diet
(2014) - et al.
Acne: the role of medical nutrition therapy
J Acad Nutr Diet
(2013) - et al.
The role of diet in acne: facts and controversies
Clin Dermatol
(2010) Nutrition and acne
Clin Dermatol
(2010)
Diet and acne
J Am Acad Dermatol
Diet and acne
Clin Dermatol
Acne and diet
Clin Dermatol
A low-glycemic-load diet improves symptoms in acne vulgaris patients: a randomized controlled trial
Am J Clin Nutr
A low-glycemic-load diet versus a conventional, high-glycemic-load diet on biochemical parameters associated with acne vulgaris: a randomized, investigator-masked, controlled trial
J Am Acad Dermatol
The effect of a low glycemic load diet on acne vulgaris and the fatty acid composition of skin surface triglycerides
J Dermatol Sci
Dietary glycemic index and glucose, insulin, insulin-like growth factor-1, insulin like growth factor binding protein-3, and leptin levels in patients with acne
J Am Acad Dermatol
Acne and milk, the diet myth, and beyond
J Am Acad Dermatol
Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults
J Am Acad Dermatol
Influence of dietary factors on actinically-induced skin cancer
Mutat Res
Diet and basal cell carcinoma of the skin in a prospective cohort of men
Am J Clin Nutr
Diet and risk of basal cell carcinoma of the skin in a prospective cohort of women
Ann Epidemiol
Nutrition and nonmelanoma skin cancers
Clin Dermatol
Vitamin supplementation and reduced risk of basal cell carcinoma
J Clin Epidemiol
Prediagnostic serum levels of carotenoids and vitamin E as related to subsequent cancer in Washington County, Maryland
Am J Clin Nutr
Intake of antioxidant nutrients and the risk of skin cancer
Eur J Cancer
Dietary supplements for established atopic eczema
Cochrane Database Syst Rev
Dietary exclusions for established atopic eczema
Cochrane Database Syst Rev
Oral evening primrose oil and borage oil for eczema
Cochrane Database Syst Rev
Prebiotics in infants for prevention of allergy
Cochrane Database Syst Rev
Probiotics in infants for prevention of allergic disease and food hypersensitivity
Cochrane Database Syst Rev
Probiotics for treating eczema
Cochrane Database Syst Rev
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child
Cochrane Database Syst Rev
Effects of early nutritional intervention on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas
Pediatrics
Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel
J Allergy Clin Immunol
Approach to suspected food allergy in atopic dermatitis. Guideline of the Task Force on Food Allergy of the German Society of Allergology and Clinical Immunology (DGAKI) and the Medical Association of German Allergologists (ADA) and the German Society of Pediatric Allergology (GPA)
J Dtsch Dermatol Ges
Vitamin D supplementation in the treatment of atopic dermatitis: a clinical trial study
J Drugs Dermatol
A randomized controlled double-blind investigation of the effects of vitamin D dietary supplementation in subjects with atopic dermatitis
J Eur Acad Dermatol Venereol
Impact of maternal supplementation with probiotics during pregnancy on atopic eczema in children: a meta-analysis
Br J Nutr
Probiotics and primary prevention of atopic dermatitis: a meta-analysis of randomized controlled studies
J Eur Acad Dermatol Venereol
The role of food allergy in childhood atopic dermatitis
J Paediatr Child Health
Response of specific immunoglobulin E to foods in children with atopic dermatitis
Arch Immunol Ther Exo (Warsz)
Food hypersensitivity in patients with childhood atopic dermatitis in Korea
Ann Dermatol
Is food allergy testing reliable in pediatric atopic dermatitis? A population-based study
Chem Immunol Allergy
The effects of elimination diet on nutritional status in subjects with atopic dermatitis
Nutr Res Pract
Practical approach to nutrition and dietary intervention in pediatric food allergy
Pediatr Allergy Immunol
Effect of exclusive breastfeeding and early solid food avoidance on the incidence of atopic dermatitis in high-risk infants at 1 year of age
Pediatr Allergy Immunol
Exclusive breastfeeding and risk of atopic dermatitis in some 8300 infants
Pediatr Allergy Immunol
Coping with acne: beliefs and perceptions in a sample of secondary school Greek pupils
J Eur Acad Dermatol Venereol
Factors believed by Jordanian acne patients to affect their acne condition
East Medit Health J
Cited by (53)
Atopic dermatitis and nutrition
2022, Clinics in DermatologyCitation Excerpt :This strategy should be done in consultation with a nutritionist to avoid nutritional deficiency. Patients should be reassessed at regular intervals because the food allergy may resolve with time.66-68 Essential fatty acids (EFAs), so-called exogenous fatty acids, cannot be synthesized by the human body and must be obtained via dietary ingestion.
Nutrition and nonmelanoma skin cancers
2022, Clinics in DermatologyCitation Excerpt :The majority of published studies to date have failed to show an association between dietary fat intake and NMSC risk.16-21 Inconsistent patterns of association might indicate chance findings; thus, in a 2014 CME review contribution, the authors recommended against implementing a low fat diet to protect against NMSC.22 Most studies did not distinguish between types of dietary fats, which may also explain the inconsistent patterns of association.
Approaches to limit systemic antibiotic use in acne: Systemic alternatives, emerging topical therapies, dietary modification, and laser and light-based treatments
2019, Journal of the American Academy of DermatologyCitation Excerpt :It has been suggested that the fat-reducing process could enhance the insulin and IGF-1-promoting elements of milk. Last, given that whey protein constitutes 20% of protein in cow's milk, its insulin-promoting component could help to explain the possible link between milk and acne.164,166,189 A case report of 5 men who developed acne in the setting of whey protein supplement consumption that improved upon discontinuation of the supplement supports this potential association.189
Influence of the Exposome on Skin Cancer
2020, Actas Dermo-SifiliograficasAdolescents’ self perceived acne-related beliefs: from myth to science
2019, Anais Brasileiros de DermatologiaCitation Excerpt :Still, there is evidence that in those with acne, washing with cleanser twice daily is an appropriate measure for better acne clearance with no irritation.25 Despite the fact that the relation of acne with diet was largely considered as a myth, a new era of research at the beginning of the millennium provided a revised and more critical viewpoint, and debate regarding the exact nutrients that influence acne pathogenesis is ongoing.26–28 Nonetheless, food-related acne beliefs have remained unchanged, and have not been influenced by general dermatologic guidelines.29,30
Cell model research status and application prospects for the evaluation of anti-glycation efficacy
2023, China Surfactant Detergent and Cosmetics
Funding sources: None.
Conflicts of interest: None declared.