Twelve patients (6 male) aged 11 to 75 years presented with solitary dermatofibromas (DFs). Seven lesions were located on the lower limbs (Fig 1, A and D, Fig 2, A and C, and Fig 3, A, B, and D), 3 lesions on the trunk (see Fig 1, B, and Fig 2, B and D), and 2 lesions on the upper limbs (see Fig 1, C, and Fig 3, C).
On dermoscopy, the case in Fig 1, A, presented a central white patch surrounded by a thin brown network, namely, the classic presentation of DF. The remaining cases displayed a nonclassic pattern. The case in Fig 1, B, mimicked a seborrheic keratosis; the cases in Fig 1, C and D, presented a prominent vascular pattern as seen in the early phases of DF. The case in Fig 2, A, was a nodular lesion with a globular pattern and in Fig 2, B, was an atrophic DF. The case in Fig 2, C, was detected in a
Histopathologic examination was suggestive of DF in all cases. The stereotypical dermoscopic pattern of DF consists of a central white patch surrounded by a thin brown network.1, 2 However, DF often deviates the latter typical pattern and mimics other benign and malignant skin tumors.1, 2 The knowledge of the dermoscopic variability of DF, coupled with a careful clinical examination that usually reveals the characteristic dimple sign, usually allows the recognition of atypicalKey message
Publication of this article was supported by 3Gen.
Funding sources: This study was supported in part by the Italian Ministry of Health (RF-2010-2316524).
Conflicts of interest: None declared.
