Case report
Herpetic geometric glossitis in an immunocompetent patient with pneumonia

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Herpetic geometric glossitis is an uncommon, clinically distinctive presentation of oral herpes simplex virus infection that affects the tongue. All published reports have been in patients who are immunocompromised. We present an immunocompetent woman with viral pneumonia who developed painful linear fissures on the back of the tongue suggestive of herpetic geometric glossitis. The diagnosis was confirmed by both biopsy specimen and immunohistochemistry. As in other cases, the patient promptly responded to treatment with antiviral therapy. The morphology, laboratory findings, and similarities to herpetic corneal dendrites are discussed. Herpetic geometric glossitis should no longer be considered as a diagnosis only in immunosuppressed individuals, but in immunocompetent persons as well.

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Case report

A 59-year-old white woman presented with a 1-week history of shortness of breath, fevers, chills, sore throat, and nonproductive cough. Two days before admission, a chest radiograph showed bilateral pulmonary infiltrates and cephalexin was started. She returned to clinic with worsening symptoms, was found to be hypoxic, and was admitted to the hospital for further care.

Her medical history was significant for coronary artery disease, hyperlipidemia, peptic ulcer disease, multinodular goiter,

Discussion

Oral HSV may have a multitude of clinical presentations depending on the immunologic status of the host, age of the patient, and anatomic site of infection. It is well established that herpetic lesions in the immunocompromised hosts are often atypical both in morphology and location.1, 2, 3, 4, 5, 6, 7, 8 Lingual lesions of HSV infection usually appear on the back surface as single or multiple tender ulcers or vesicles that rapidly erode. It is now established that lingual HSV may also rarely

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    Of these atypical reactivations, HGG shows a characteristic branching pattern that resembles the dendritic corneal ulcers produced by HSV. Other clinical manifestations of HGG include papules, erythematous nodules, and ulcers over the tongue, all of which are associated with severe pain.1-3,7 During the evaluation of patients with chronic HIV infection and sudden development of oral lesions, it is important to rule out other infectious conditions, such as secondary syphilis.

  • Diseases of the tongue

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    Therapy should be initiated in the first 72 hours of onset. Herpetic geometric glossitis, a unique form of recurrent HSV infection described in 1993,62 is classically described as linear and symmetric striations and fissures of the dorsal aspect of the tongue in an immunocompromised individual, although there are rare reports of herpetic geometric glossitis in immunocompetent patients as well63 (Figure 7, b). This condition is characterized by exquisite tenderness and pain within the atrophic and uniquely branched and fissured lesions.62,64

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    2020, European Journal of Dermatology

Funding sources: None.

Conflicts of interest: None declared.

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