DermatopathologyHeterotopic salivary gland tissue in the neck
Section snippets
Methods
After approval of the institutional review board at Lifespan-affiliated hospitals (Rhode Island Hospital and Miriam Hospital), a large tertiary care center, anatomic pathology files were searched for all cases containing “ectopic salivary” in the final diagnosis, from 1983 through 2005. Fourteen cases were identified for possible inclusion in this retrospective case series; after an initial review, 3 cases were excluded: one branchial cleft cyst containing salivary rests, one accessory gland,
Results
The clinical and pathologic findings for the 11 cases are summarized in Table I. There were 4 female and 7 male patients, with age range at surgery from 5 months to 64 years (median 5 years). In 5 of the cases, the lesion was noted within the first month of life. Patients presented with sinuses that had intermittent drainage, localized nodules, or a dimple. In one case ectopic salivary tissue was an incidental finding related to a parathyroidectomy. Eight cases occurred on the right side of the
Discussion
HSGT of the neck should remain within the dermatologist's differential diagnosis for draining sinus for all age groups. Although most lesions in this series were noted at birth or early in childhood, identification may not occur until later in life because of the small size of the draining orifices3 and the relative rarity of pain and infection compared with that associated with branchial cleft fistulas13, 14; one patient delayed treatment until 64 years of age in spite of the congenital nature
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Cited by (31)
A case report: Congenital salivary fistula from the sublingual gland in an adult
2022, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyCitation Excerpt :Acquired salivary fistulas are more frequently seen and result mostly from surgery, trauma, inflammation, or malignant tumor. Congenital salivary fistulas are unusual; they have been reported to originate from an ectopic (heterotopic) salivary gland [1–30], parotid gland, or accessory parotid gland [31–43,45–53], and, rarely, submandibular gland [54,58], sublingual gland [55], or minor salivary gland [44]. The embryologic origin of congenital salivary fistulas is thought to be abnormalities in the developmental process of salivary glands, but the detailed mechanism remains unclear.
Heterotopic Salivary Gland Tissue
2021, Actas Dermo-SifiliograficasCartilaginous choristomas in tonsillectomy specimen: A prospective analysis
2019, International Journal of Pediatric OtorhinolaryngologyCongenital cervical salivary fistula: A case report
2012, Revue de Stomatologie et de Chirurgie Maxillo-FacialeBasal cell adenocarcinoma arising in salivary gland metaplasia of the breast: A novel salivary gland-type tumor developing in the breast
2012, Human PathologyCitation Excerpt :The authors were not able to determine if the tissue was ectopic salivary gland tissue or if it had developed through a metaplastic process [14,15]. Ectopic salivary gland tissue—normal salivary gland tissue located in an abnormal anatomical location—has been described in areas as diverse as the anterior cheek, lower anterior sternocleidomastoid muscle, parathyroid, muscles of the tongue, mandible, middle ear, pituitary, mediastinum, prostate, vulva, and rectum [16-21]. As with all ectopic tissues, ectopic salivary gland tissue can undergo neoplastic transformation, with Warthin tumors and pleomorphic adenomas being the most commonly described neoplasms [17,19-21].
Bilateral heterotopic salivary gland tissue (HSGT) in the lower neck: A report of a rare case with review of literature
2010, International Journal of Pediatric Otorhinolaryngology Extra
Funding sources: None.
Conflicts of interest: None declared.
Previously partially presented as a poster at the American Academy of Dermatology Summer Academy Meeting, Chicago, Ill, July 21-3, 2005.
Reprints not available from the authors.