ORIGINAL ARTICLESIncreased risk of serious injury following an initial prescription for diphenhydramine
REFERENCES (31)
Falls among the elderly: epidemiology and prevention
Am J Prev Med
(1988)- et al.
Sedative effects of antihistamines
J Allergy Clin Immunol
(1987) - et al.
A review of the effects of antihista-mines on mental processes related to automobile driving
J Allergy Clin Immunol
(1990) - et al.
A cost of illness study of allergic rhinitis in the United States
J Allergy Clin Immunol
(1997) - et al.
A case-control study of prosthetic implants and selected chronic diseases
Ann Epidemiol
(1996) - et al.
Risk factors for falls among elderly persons living in the community
N Engl J Med
(1988) - et al.
Benzodiazepine tranquilizers and the risk of accidental injury
Am J Public Health
(1990) - et al.
Psychotropic drug use and the risk of hip fracture
N Engl J Med
(1987) - et al.
Benzodiazepines of long and short half-life and the risk of hip fracture
JAMA
(1989) - et al.
Psychoactive drugs and the risk of injurious motor vehicle crashes in elderly drivers
Am J Epidemiol
(1992)
Drugs affecting postural stability and other risk factors in the hip fracture epidemic – a case-control study
Comm Med.
Psychoactive medication and injurious motor vehicle crashes involving older drivers
Epidemiology
Medical conditions and motor vehicle collisions injuries in older adults
J Am Geriatr Soc
Occupational injuries and medication use
Am J Industrial Med
Characterization of daytime sleepiness and psychomotor performance following H1 receptor antagonists
Ann Allergy Asthma Immunol
Cited by (45)
Diphenhydramine: Time to Move on?
2022, Journal of Allergy and Clinical Immunology: In PracticeAssociation between childhood allergic disease, psychological comorbidity, and injury requiring medical attention
2014, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Further, recent studies have found that allergic disorders are associated with increased mental health comorbidity.6,7 Impaired sleep,8,9 sedating antihistamines,10,11 and mental health disorders12–19 have been associated with unintentional injury. Therefore, it is logical that patients with allergic disorders are at increased risk for unintentional injury.
The diagnosis and management of acute and chronic urticaria: 2014 update
2014, Journal of Allergy and Clinical ImmunologyAllergy/respiratory and cardiovascular drugs
2010, Sleep Medicine ClinicsCitation Excerpt :In addition, controlled studies evaluating psychomotor skills, memory, attention, and actual driving performance confirm that the first-generation H1 antagonists impair performance whereas the second-generation drugs are much less likely to do so.44,52–54 First-generation drugs have been associated with injuries55,56 and traffic accidents57 as well. Even when administered at night, sedation and psychomotor impairment may be present the following morning.58
The use of electronic pharmacy data to investigate prescribed medications and fatal motor vehicle crashes in a military population, 2002-2006
2010, Accident Analysis and Prevention
The research project was supported by Schering Corporation, which had no editorial control over the decision to publish the findings or the content of the manuscript.