Journal of the American Academy of Dermatology
Polymorphous light eruption: A clinical, photobiologic, and follow-up study of 110 patients☆,☆☆
Section snippets
PATIENTS AND METHODS
We selected for analysis all 110 patients with PMLE who underwent diagnostic phototests in the period 1985 through 1991. This period was chosen to allow for a possible follow-up period of at least 5 years. The diagnosis of PMLE was based on the clinical and, if necessary, histologic features, including the results of the phototests. We excluded those patients with a concomitant dermatosis that can be provoked by sunlight, such as Jessner’s lymphocytic infiltration of the skin,30 lupus
RESULTS
In this study 110 patients were included (35 men and 75 women). The mean duration of complaints before they came to our photodermatology unit was 9.2 years (men 8.2; women 9.7 years). The course of the disease activity during that period was progressive in 86 patients, stationary in 19, and unknown in 5. We found a significant difference between men and women with regard to the age at onset (P < .01; the significance tests35 were based on the normal distribution). The mean age at onset was 34
DISCUSSION
In this retrospective study of 110 patients (35 men, 75 women) with PMLE, we analyzed the clinical aspects, the photodiagnostic test results, and the results of our therapy. We examined the data of the patients who underwent diagnostic phototests in the period of 1985 through 1991.
The age at onset differed significantly between men and women (46 vs 28 years). According to the historical data, the clinical picture showed papular lesions (61 patients), papulovesicular lesions (27 patients, almost
Acknowledgements
We thank Professor J. C. van der Leun for his comment on the manuscript.
References (36)
Polymorphous light eruption
J Am Acad Dermatol
(1980)- et al.
Immune sensitization against epidermal antigens in polymorphous light eruption
J Am Acad Dermatol
(1991) - et al.
Drug photosensitivity, idiopathic photodermatoses and sunscreens
J Am Acad Dermatol
(1996) - et al.
Polymorphous light eruption: experimental reproduction of skin lesions
J Am Acad Dermatol
(1982) - et al.
Polymorphous light eruption: action spectrum and photoprotection
J Am Acad Dermatol
(1986) - et al.
Results of evaluation of 203 patients for photosensitivity in a 7.3 year period
J Am Acad Dermatol
(1995) - et al.
Cutaneous photosensitivity diseases induced by exogenous agents
J Am Acad Dermatol
(1995) - et al.
Actinic reticuloid: a clinical, photobiologic, histopathologic, and follow-up study of 16 patients
J Am Acad Dermatol
(1989) Chronic actinic dermatitis
J Am Acad Dermatol
(1993)- et al.
Polymorphic light eruption: prevalence in Australia and England
Br J Dermatol
(1994)
Chronic polymorphic light eruption (a study of 25 cases)
Br J Dermatol
Polymorphous light eruption
J Invest Dermatol
Current aspects of polymorphous light eruptions in Sweden
Photodermatology
Polymorphe Lichtdermatose. Klinische Daten und Testbefunde
Hautarzt
Polymorphic light eruption
Photodermatol
The polymorphic phototest reaction
Arch Dermatol
Photodermatoses: diagnostic procedures and their interpretation
Photodermatology
Die Polymorphe Lichtdermatose - Photobiologische Diagnostik und Therapie
Z Hautkr
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Reprint requests: H. van Weelden, MSc, Department of Dermatology, University Hospital Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
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