TY - JOUR T1 - Outbreak of Cutaneous Leishmaniasis in Fuenlabrada, Madrid JO - Actas Dermo-Sifiliográficas T2 - AU - Aguado,M. AU - Espinosa,P. AU - Romero-Maté,A. AU - Tardío,J.C. AU - Córdoba,S. AU - Borbujo,J. SN - 15782190 M3 - 10.1016/j.adengl.2013.03.005 DO - 10.1016/j.adengl.2013.03.005 UR - https://actasdermo.org/es-outbreak-cutaneous-leishmaniasis-in-fuenlabrada-articulo-S157821901300067X AB - BackgroundLeishmaniasis, an endemic infection in Spain, is caused by protozoan parasites of the Leishmania genus. Between 2010 and 2012, there was an outbreak of cutaneous and visceral leishmaniasis in Fuenlabrada, Madrid. ObjectivesTo describe the cases of cutaneous leishmaniasis diagnosed over a 17-month period at the dermatology department of Hospital de Fuenlabrada. Material and methodsWe analyzed the epidemiological, clinical, histological, and microbiological features of each case and also evaluated the treatments administered and outcomes. ResultsWe studied 149 cases. The incidence of cutaneous leishmaniasis showed a peak in the age range between 46 and 60 years and was similar in men and women. At the time of consultation, the lesions had been present for between 2 and 6 months in the majority of patients. The most common clinical presentation was with erythematous plaques and papules without crusts (52% of cases). Lesions were most often located in sun-exposed areas and were multiple in 57% of patients. In 67% of cases, the histological study showed non-necrotizing granulomatous dermatitis with no evidence of parasites using conventional staining methods. Diagnosis was confirmed by polymerase chain reaction (PCR) in 98% of patients. In the remaining cases, the histological study revealed Leishman-Donovan bodies in the skin. Intralesional pentavalent antimonials were the most commonly used drugs (76% of cases) and produced satisfactory results. ConclusionsWe have presented a large series of cases of cutaneous leishmaniasis diagnosed in the context of an outbreak. Multiple papules were the most common clinical presentation, with histology that showed non-necrotizing granulomatous dermatitis with no evidence of parasites. PCR of skin samples was the test that most frequently provided the diagnosis. ER -