TY - JOUR T1 - Comparative Analysis of Umbilical Nodules in Male and Female Patients: A 20-Year Retrospective Study JO - Actas Dermo-Sifiliográficas T2 - AU - Onyishi,N.T. AU - Okafor,O.C. SN - 00017310 M3 - 10.1016/j.ad.2022.03.001 DO - 10.1016/j.ad.2022.03.001 UR - https://actasdermo.org/es-comparative-analysis-umbilical-nodules-in-articulo-S0001731022001995 AB - Background and aimsThe umbilicus is known to receive metastatic malignancy from diverse visceral organs. Accurate and correct diagnosis of umbilical lesions is imperative since metastatic malignancy signifies a serious underlying situation with dire prognosis. Identification of demographic features that can contribute to diagnostic resolution of umbilical lesions is desirable. We analyzed umbilical biopsies received over a 20-year period to determine any gender distinctive attributes of umbilical nodules. Materials and methodAll umbilical biopsies received in our department from 1st January 2000 to 31st December 2019 were identified and analyzed. Data acquired included patient's gender, age, date of biopsy, type of biopsy and histopathological diagnoses and these were analyzed using computer software. ResultsThere were 67 umbilical biopsies from 22 males and 45 females giving a male: female ratio of 1:2. The difference between the mean age (SD) of male patients [47.8 years (19.4 years)] and that of the females [42.8 years (13.9 years)] was not statistically significant (p=0.28). Twenty-five of the 67 umbilical lesions were benign while 42 were malignant. About 90.9% of biopsies in males were malignant and 9.1% benign while 48.9% of biopsies in females were malignant and 51.1% benign. The odds of malignant umbilical biopsy in males compared to females is 10.5 [OR=10.5; 95% CI=2.2–50.1)]. ConclusionUmbilical biopsies were relatively infrequent in our practice and were more common in females than males. Umbilical lesions presented by males are mostly malignant. Overall, 78% of all umbilical lesions in females were of gynecological derivation. ER -