Journal Information
Vol. 100. Issue S2.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte II
Pages 110-113 (December 2009)
Vol. 100. Issue S2.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte II
Pages 110-113 (December 2009)
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Melasma Update
Actualización en melasma
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H. Young Kanga, J.-P. Ortonneb,
Corresponding author
ortonne@unice.fr

Correspondence: Department of Dermatology. Archet-2 Hospital. 151 Route St Antoine de Ginestiere, BP 3079. 06202 Nice Cedex 3, France.
a Department of Dermatology. Ajou University School of Medicine. Suwon. Korea
b Department of Dermatology. Archet-2 Hospital. Nice. France
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Article information
Abstract

Melasma is a common acquired hyperpigmentary disorder of the face. However, the pathogenesis of melasma remains largely unknown and the treatment is still challenging. This article discusses histology of melasma in view of melanin pigmentation with a more in depth question about number of melanocytes and melanophages in dermis of melasma. We also explore the current understanding of etiopathogenesis of melasma. We conclude the review with a discussion of important issues that should be addressed in future research to find effective treatment modality of melasma.

Key words:
melasma
histology
pathogenesis
treatment
Resumen

El melasma es un trastorno de la pigmentación facial, adquirido y frecuente. Sin embargo, se desconoce en gran medida su patogenia y el tratamiento continúa siendo un reto. En este artículo se discute la histología del melasma desde la perspectiva de la pigmentación melánica, profundizando más sobre el número de melanocitos y melanófagos en la dermis del melasma. También se comenta el conocimiento actual sobre la etiopatogenia del melasma. Concluimos la revisión con una discusión sobre aspectos importantes que se deben abordar en futuras investigaciones para encontrar un tratamiento eficaz del melasma.

Palabras clave:
melasma
histología
etiopatogenia
tratamiento
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