Journal Information
Vol. 107. Issue 3.
Pages 249 (April 2016)
Vol. 107. Issue 3.
Pages 249 (April 2016)
Images in Dermatology
DOI: 10.1016/j.adengl.2016.01.014
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Generalized Keratosis Lichenoides Chronica
Queratosis liquenoide crónica generalizada
R. Santesteban-Muruzábal
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Corresponding author.
, M. Larrea-García, I. Yanguas-Bayona
Servicio de Dermatología, Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain
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In a 38-year-old man, we observe violaceous hyperkeratotic desquamative plaques that coalesce to form a reticular pattern occupying almost the entire body surface area (Fig. 1A and B). The lesions first appeared 5 years earlier. The biopsy shows a patchy lichenoid infiltrate centered around the infundibula (Fig. 1C), vacuolar degeneration at the dermal-epidermal junction, acanthosis, tiered parakeratosis, and necrotic keratinocytes (Fig. 1D). With these observations, it was possible to diagnose generalized keratosis lichenoides chronica (KLC).

Figure 1

KLC is a very uncommon inflammatory disease of unknown pathogenesis that presents as violaceous hyperkeratotic papules and plaques resembling lichen planus. The lesions can follow a linear and/or reticular pattern. It is a symmetrical and bilateral disorder that involves the trunk and limbs and, less frequently, the neck and feet. It may even on occasions become generalized. It usually first presents in young adults, with no predilection for sex or race. Facial lesions similar to seborrheic eczema or perioral dermatitis may also occur, as well as other processes such as palmoplantar keratoderma and nail dystrophy. Treatment is often complicated given the lack of response.

This case is noteworthy given the generalized form the disease. The fact that the condition was allowed to progress so far can be explained by the lack of medical care received as the patient was living in a refugee camp without any access to specialized care.

Please cite this article as: Santesteban-Muruzábal R, Larrea-García M, Yanguas-Bayona I. Queratosis liquenoide crónica generalizada. Actas Dermosifiliogr. 2016;107:249.

Copyright © 2015. AEDV
Actas Dermo-Sifiliográficas (English Edition)

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