TY - JOUR T1 - Calciphylaxis: Risk Factors and Histologic Findings in a Case Series From a Tertiary Care Referral Hospital JO - Actas Dermo-Sifiliográficas T2 - AU - Sánchez-Pujol,M.J. AU - Docampo Simón,A. AU - Illán Gambín,F. AU - Niveiro de Jaime,M. AU - Blanes Martínez,M. SN - 15782190 M3 - 10.1016/j.adengl.2021.07.003 DO - 10.1016/j.adengl.2021.07.003 UR - https://actasdermo.org/en-calciphylaxis-risk-factors-histologic-findings-articulo-S1578219021002018 AB - Recent years have seen important advances in our understanding of calciphylaxis, especially regarding newly identified risk factors and histologic findings that may aid diagnosis. This retrospective study of cases of calciphylaxis treated in our hospital in the last 13 years focuses on newly revealed aspects of this disease. We describe 16 patients (62.5% women; mean age, 67.9 years). In addition to advanced kidney disease (in 75% of our patients), other factors associated with the presence of calciphylaxis were a history of treatments related to phosphorus and calcium metabolism (75%) and anticoagulation (62.5%), usually with vitamin-K antagonists. Histology showed alterations in elastic fibers in only 25% of the biopsy specimens. Eleven of the patients died: sepsis was most often the cause. ER -