TY - JOUR T1 - Granulomatous Reaction in a Patient With Metastatic Melanoma Treated With Ipilimumab: First Case Reported With Isolated Cutaneous Findings JO - Actas Dermo-Sifiliográficas T2 - AU - Cervantes,J. AU - Rosen,A. AU - Dehesa,L. AU - Dickinson,G. AU - Alonso-Llamazares,J. SN - 15782190 M3 - 10.1016/j.adengl.2018.11.013 DO - 10.1016/j.adengl.2018.11.013 UR - https://actasdermo.org/en-granulomatous-reaction-in-patient-with-articulo-S1578219018304116 AB - Granulomatous sarcoidosis-like reactions affecting multiple organ systems at one time have infrequently been described within weeks to months after initiation of Ipilimumab. We present the first case of a 67-year-old man with isolated cutaneous granulomatous reaction involving the trunk, extremities, and face after eighteen months of treatment with ipilimumab for metastatic melanoma. This case documents the eruption of isolated cutaneous granulomatous reaction as a late treatment-related adverse effect of ipilimumab, highlighting the importance of adequate, prolonged follow-up. ER -