Statistics

 array:24 [
  "pii" => "S1578219021002365"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.07.024"
  "estado" => "S300"
  "fechaPublicacion" => "2021-10-01"
  "aid" => "2601"
  "copyrightAnyo" => "2021"
  "documento" => "simple-article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "crp"
  "cita" => "Actas Dermosifiliogr. 2021;112:851-3"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S000173102100096X"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2020.01.011"
      "estado" => "S300"
      "fechaPublicacion" => "2021-10-01"
      "aid" => "2601"
      "copyright" => "AEDV"
      "documento" => "simple-article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "crp"
      "cita" => "Actas Dermosifiliogr. 2021;112:851-3"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">CARTAS CIENT&#205;FICO-CL&#205;NICAS</span>"
        "titulo" => "Dactilitis granulomatosa como manifestaci&#243;n inusual de la sarcoidosis"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "851"
            "paginaFinal" => "853"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Granulomatous Dactylitis&#58; An Unusual Finding in Sarcoidosis"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 1056
                "Ancho" => 1305
                "Tamanyo" => 168103
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Lesiones de lupus pernio faciales eritematosas con costra en superficie&#46; Dactilitis de 3 dedos del pie derecho asociada a onicopat&#237;a&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "I&#46; Garc&#237;a-Morales, E&#46; S&#225;nchez Garc&#237;a, A&#46; Crespo Cruz, J&#46; Escudero"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "I&#46;"
                "apellidos" => "Garc&#237;a-Morales"
              ]
              1 => array:2 [
                "nombre" => "E&#46;"
                "apellidos" => "S&#225;nchez Garc&#237;a"
              ]
              2 => array:2 [
                "nombre" => "A&#46;"
                "apellidos" => "Crespo Cruz"
              ]
              3 => array:2 [
                "nombre" => "J&#46;"
                "apellidos" => "Escudero"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021002365"
          "doi" => "10.1016/j.adengl.2021.07.024"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002365?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S000173102100096X?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000009/v1_202110020514/S000173102100096X/v1_202110020514/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S1578219021002298"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.017"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2600"
    "documento" => "simple-article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "crp"
    "cita" => "Actas Dermosifiliogr. 2021;112:853-6"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
      "titulo" => "Pityriasis Rosea-like Eruption Induced by Imatinib in a Patient With a Gastrointestinal Stromal Tumor"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "853"
          "paginaFinal" => "856"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Erupci&#243;n pitiriasis rosada-<span class="elsevierStyleItalic">like</span> inducida por imatinib en paciente con tumor del estroma gastrointestinal"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0010"
          "etiqueta" => "Figure 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 2152
              "Ancho" => 2508
              "Tamanyo" => 1364806
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0010"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; Histologic image highlighting a superficial dermal infiltrate&#46; B&#44; Higher-magnification view showing spongiotic dermatitis with a perivascular infiltrate and focal parakeratosis&#46; C&#44; Detail of predominantly lymphocytic perivascular infiltrate&#46; D&#44; Detail of spongiotic dermatitis with a focus of parakeratosis&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "S&#46; Valenzuela-Ubi&#241;a, I&#46; Villegas-Romero, D&#46; Jim&#233;nez-Gallo, M&#46; Linares-Barrios"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "S&#46;"
              "apellidos" => "Valenzuela-Ubi&#241;a"
            ]
            1 => array:2 [
              "nombre" => "I&#46;"
              "apellidos" => "Villegas-Romero"
            ]
            2 => array:2 [
              "nombre" => "D&#46;"
              "apellidos" => "Jim&#233;nez-Gallo"
            ]
            3 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Linares-Barrios"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021000958"
        "doi" => "10.1016/j.ad.2020.01.010"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021000958?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002298?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002298/v1_202110091021/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S1578219021002390"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.07.027"
    "estado" => "S300"
    "fechaPublicacion" => "2021-10-01"
    "aid" => "2660"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "sco"
    "cita" => "Actas Dermosifiliogr. 2021;112:849-50"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Resident&#39;s Forum</span>"
      "titulo" => "RF - Mohs Micrographic Surgery&#58; Same-Day or Delayed Reconstruction&#63;"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "849"
          "paginaFinal" => "850"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "FR - Cirug&#237;a microgr&#225;fica de Mohs&#46; &#191;Cierre inmediato o cierre diferido&#63;"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "T&#46; Montero-Vilchez, A&#46; Rodriguez-Tejero, J&#46; Tercedor-Sanchez"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Montero-Vilchez"
            ]
            1 => array:2 [
              "nombre" => "A&#46;"
              "apellidos" => "Rodriguez-Tejero"
            ]
            2 => array:2 [
              "nombre" => "J&#46;"
              "apellidos" => "Tercedor-Sanchez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731021001782"
        "doi" => "10.1016/j.ad.2019.09.016"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021001782?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002390?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002390/v1_202110091021/en/main.assets"
  ]
  "en" => array:16 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Granulomatous Dactylitis&#58; An Unusual Finding in Sarcoidosis"
    "tieneTextoCompleto" => true
    "saludo" => "To the Editor&#58;"
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "851"
        "paginaFinal" => "853"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "I&#46; Garc&#237;a Morales, E&#46; S&#225;nchez Garc&#237;a, A&#46; Crespo Cruz, J&#46; Escudero"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "I&#46;"
            "apellidos" => "Garc&#237;a Morales"
            "email" => array:1 [
              0 => "irenegmorales@gmail.com"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "E&#46;"
            "apellidos" => "S&#225;nchez Garc&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "A&#46;"
            "apellidos" => "Crespo Cruz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "J&#46;"
            "apellidos" => "Escudero"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Unidad de Gesti&#243;n Cl&#237;nica de Dermatolog&#237;a&#44; Hospital Universitario Virgen Macarena&#44; Sevilla&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Medicina Interna&#44; Hospital Universitario Nuestra Se&#241;ora de Valme&#44; Sevilla&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Unidad de Gesti&#243;n Cl&#237;nica de Dermatolog&#237;a&#44; Hospital Universitario Nuestra Se&#241;ora de Valme&#44; Sevilla&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Dactilitis granulomatosa como manifestaci&#243;n inusual de la sarcoidosis"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 680
            "Ancho" => 905
            "Tamanyo" => 178504
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histologic study of the facial skin lesions with granulomas in the middle and deep dermis&#44; with no central necrosis or lymphocytic corona&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Sarcoid dactylitis is a rare manifestation&#44; observed in 0&#46;2&#37; of cases of sarcoidosis&#46; It usually courses with swelling of the fingers or toes&#44; mainly affecting the middle phalanges and&#44; less often&#44; the distal phalanges&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">A 38-year-old woman visited our department with inflammation and pain in the toes of the right foot&#44; accompanied by abnormal nails&#44; which had appeared 3 months earlier&#46; The patient presented erythematous&#44; lupoid facial lesions that had appeared a year earlier and were associated with bilateral enlarged cervical lymph nodes&#46; Examination revealed erythema with edema and swelling in the first 3 toes of the right foot&#44; associated with dystrophic toenails&#44; and erythematous lesions with adhered crusts on the nose&#44; forehead&#44; and cheeks &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">The biopsy of the cervical lymph nodes revealed a sarcoid granulomatous lymphadenitis&#44; with negative staining for Ziehl-Neelsen&#44; Grocott&#44; and PAS&#46; Blood cultures and urine tests were negative for aerobes&#44; anaerobes&#44; and <span class="elsevierStyleItalic">Mycobacterium</span> species were negative&#46; The histologic study of the skin lesions on the face and right foot revealed the existence of naked granulomas&#44; with no central necrosis or lymphocytic corona&#44; in the deep and middle dermis &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Blood tests showed increased levels of angiotensin-converting enzyme and acute phase reactants&#44; and serology for syphilis was negative&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">The x-ray study revealed destruction of the distal phalanx of the first toe&#44; with signs of bone resorption and tendinitis&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">The CT scan showed a small number of enlarged hilar&#44; subcarinal mediastinal&#44; and retroperitoneal lymph nodes associated with bilateral micronodules in the upper third of the lung fields&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">A diagnosis of sarcoid dactylitis in the context of systemic sarcoidosis was made and treatment was initiated with oral corticosteroids associated with hydroxychloroquine&#59; a slight improvement was achieved and this treatment was therefore suspended&#46; Treatment was begun with 150&#160;mg&#47;d of azathioprine&#46; After 6 months of treatment&#44; the swelling of the toes had been reduced and the crusts of the facial lesions had disappeared &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; After a year of treatment only the erythematous lesions persist&#44; with no crust or swelling&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0040" class="elsevierStylePara elsevierViewall">Bone involvement in sarcoidosis usually manifests in the form of joint pain&#44; whereas deforming arthritis is rare&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Two patterns of appearance of sarcoid joint disease exist&#58; an early form of presentation that occurs in the first 6 months and is usually observed in L&#246;fgren syndrome&#44; and a late-onset form that affects multiple joints&#44; generally those of the small bones of the hands and feet and which appears after 6 months&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> They are often associated with nail disorders&#44; acropachy with racket nails&#44; or acrosclerosis&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">Radiologically&#44; sarcoid dactylitis is characterized by trabecular abnormalities with a honeycomb or barred pattern&#44; which may be associated with cystic formations and a periosteal reaction&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">Histologically&#44; in bone lesions&#44; noncaseating granulomas are found that invade the phalanges and the surrounding soft tissue&#46; This granulomatous dactylitis is associated with a worse outcome and greater risk of systemic involvement and of lupus pernio in chronic sarcoidosis&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">Lupus pernio is one of the most characteristic lesions of sarcoidosis&#44; which is more frequent in Caucasian women with long-term disease&#44; as in our case&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> It is characterized by pink or violaceous papular lesions on the nose&#44; cheeks&#44; ears&#44; lips&#44; or scalp&#46; It tends to be associated with chronic sarcoidosis and involvement of the upper respiratory apparatus&#46; If the lupus pernio lesions are located on the fingers or toes&#44; cystic bone lesions on the phalanges of the affected members are often observed&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">Bone involvement tends to be associated with a fourfold higher mortality&#59; however&#44; patients do not usually have symptoms&#44; despite the presence of abnormal radiologic findings&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Treatment of sarcoid dactylitis requires the use of high-dose corticosteroids associated with antimalarial drugs and methotrexate&#46; In our patient&#44; we ruled out the use of methotrexate owing to the patient&#8217;s stated desire to have children and we therefore used azathioprine for some time&#44; and we even considered the use of adalimumab&#44; but this was refused by the patient&#46; The use of anti-TNF-&#945; agents&#44; infliximab&#44; or adalimumab is considered third-line treatment in sarcoidosis&#44; and is useful in refractory cases or cases with ocular or systemic involvement&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflicts of Interest</span><p id="par0070" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:2 [
        0 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Conflicts of Interest"
        ]
        1 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Garc&#237;a Morales I&#44; S&#225;nchez Garc&#237;a E&#44; Crespo Cruz A&#44; Escudero J&#46; Dactilitis granulomatosa como manifestaci&#243;n inusual de la sarcoidosis&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;851&#8211;853&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "fig0005"
        "etiqueta" => "Figure 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 1056
            "Ancho" => 1305
            "Tamanyo" => 168103
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Erythematous lupus pernio lesions on the face with crusts on the surface&#46; Dactylitis in 3 toes of the right foot associated with nail disease&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "fig0010"
        "etiqueta" => "Figure 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 680
            "Ancho" => 905
            "Tamanyo" => 178504
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Histologic study of the facial skin lesions with granulomas in the middle and deep dermis&#44; with no central necrosis or lymphocytic corona&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "fig0015"
        "etiqueta" => "Figure 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1097
            "Ancho" => 1305
            "Tamanyo" => 162544
          ]
        ]
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Figure "
            "rol" => "short"
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Favorable clinical course after 3 months of systemic treatment with prednisone associated with hydroxychloroquine&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dactylitis in sarcoidosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "T&#46; Mori"
                            1 => "T&#46; Yamamoto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Dermatol"
                        "fecha" => "2017"
                        "volumen" => "44"
                        "paginaInicial" => "e340"
                        "paginaFinal" => "1"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lupus pernio with multiples bone cysts in the fingers"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46; Yayoi"
                            1 => "I&#46; Naoya"
                            2 => "I&#46; Osamu"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1346-8138.2010.00900.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Dermatol"
                        "fecha" => "2010"
                        "volumen" => "37"
                        "paginaInicial" => "812"
                        "paginaFinal" => "814"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20883366"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis&#58; immunology&#44; rheumatic involvement&#44; and therapeutics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Barnard"
                            1 => "L&#46;S&#46; Newman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00002281-200101000-00014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Curr Opin Rheumatol"
                        "fecha" => "2001"
                        "volumen" => "13"
                        "paginaInicial" => "84"
                        "paginaFinal" => "91"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11148721"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Lytic lesion involving the first phalanx&#58; sarcoidosis should be suspected&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "Z&#46; Alaya"
                            1 => "A&#46; Mzabi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.11604/pamj.2017.26.210.12076"
                      "Revista" => array:5 [
                        "tituloSerie" => "Pan Afr Med J"
                        "fecha" => "2017"
                        "volumen" => "26"
                        "paginaInicial" => "210"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28690725"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoid dactylitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "P&#46; Pitt"
                            1 => "E&#46;B&#46; Hamilton"
                            2 => "E&#46;H&#46; Innes"
                            3 => "K&#46;D&#46; Morley"
                            4 => "B&#46;E&#46; Monk"
                            5 => "G&#46;R&#46; Hughes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/ard.42.6.634"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "1983"
                        "volumen" => "42"
                        "paginaInicial" => "634"
                        "paginaFinal" => "639"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6606399"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sarcoidosis involving the muscluloskeletal system"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;A&#46; Zisman"
                            1 => "A&#46;F&#46; Shorr"
                            2 => "J&#46;P&#46; Lynch"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1055/s-2002-36520"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Respir Crit Care Med"
                        "fecha" => "2002"
                        "volumen" => "23"
                        "paginaInicial" => "555"
                        "paginaFinal" => "570"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16088651"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Efficacy of adalimumab in sarcoidosis patients who developed intolerance to infliximab"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "H&#46;A&#46; Crommelin"
                            1 => "L&#46;M&#46; Van der Burg"
                            2 => "A&#46;D&#46; Vorselaars"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.rmed.2016.04.011"
                      "Revista" => array:6 [
                        "tituloSerie" => "Respir Med"
                        "fecha" => "2016"
                        "volumen" => "115"
                        "paginaInicial" => "72"
                        "paginaFinal" => "77"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27215507"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000009/v1_202110091021/S1578219021002365/v1_202110091021/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6157"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case and Research Letters"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000009/v1_202110091021/S1578219021002365/v1_202110091021/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021002365?idApp=UINPBA000044"
]