Statistics

 array:25 [
  "pii" => "S1578219021001542"
  "issn" => "15782190"
  "doi" => "10.1016/j.adengl.2021.03.017"
  "estado" => "S300"
  "fechaPublicacion" => "2021-06-01"
  "aid" => "2589"
  "copyright" => "AEDV"
  "copyrightAnyo" => "2021"
  "documento" => "article"
  "crossmark" => 1
  "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
  "subdocumento" => "fla"
  "cita" => "Actas Dermosifiliogr. 2021;112:516-9"
  "abierto" => array:3 [
    "ES" => true
    "ES2" => true
    "LATM" => true
  ]
  "gratuito" => true
  "lecturas" => array:1 [
    "total" => 0
  ]
  "Traduccion" => array:1 [
    "es" => array:20 [
      "pii" => "S0001731021000089"
      "issn" => "00017310"
      "doi" => "10.1016/j.ad.2021.01.001"
      "estado" => "S300"
      "fechaPublicacion" => "2021-06-01"
      "aid" => "2589"
      "copyright" => "AEDV"
      "documento" => "article"
      "crossmark" => 1
      "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
      "subdocumento" => "fla"
      "cita" => "Actas Dermosifiliogr. 2021;112:516-9"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:1 [
        "total" => 0
      ]
      "es" => array:12 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">DERMATOLOG&#205;A PR&#193;CTICA</span>"
        "titulo" => "Seguridad en procedimientos dermatol&#243;gicos&#58; crisis hipertensiva y arritmias potencialmente malignas"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "516"
            "paginaFinal" => "519"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Safety in Dermatologic Procedures&#58; Hypertensive Crises and Potentially Fatal Arrhythmias"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "P&#46; Rodr&#237;guez-Jim&#233;nez, R&#46; Sampedro-Ruiz, I&#46; Imaz, P&#46; Chicharro"
            "autores" => array:4 [
              0 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Rodr&#237;guez-Jim&#233;nez"
              ]
              1 => array:2 [
                "nombre" => "R&#46;"
                "apellidos" => "Sampedro-Ruiz"
              ]
              2 => array:2 [
                "nombre" => "I&#46;"
                "apellidos" => "Imaz"
              ]
              3 => array:2 [
                "nombre" => "P&#46;"
                "apellidos" => "Chicharro"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S1578219021001542"
          "doi" => "10.1016/j.adengl.2021.03.017"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => true
            "ES2" => true
            "LATM" => true
          ]
          "gratuito" => true
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021001542?idApp=UINPBA000044"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021000089?idApp=UINPBA000044"
      "url" => "/00017310/0000011200000006/v1_202106081644/S0001731021000089/v1_202106081644/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:20 [
    "pii" => "S1578219021001463"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.03.010"
    "estado" => "S300"
    "fechaPublicacion" => "2021-06-01"
    "aid" => "2578"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "fla"
    "cita" => "Actas Dermosifiliogr. 2021;112:520-7"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Original Article</span>"
      "titulo" => "Fibrous Hamartoma of Infancy&#58; A Series of 21 Cases and Review of the Literature"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "520"
          "paginaFinal" => "527"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Hamartoma fibroso de la infancia&#58; una serie de 21 casos y revisi&#243;n de la literatura"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0015"
          "etiqueta" => "Figure 3"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr3.jpeg"
              "Alto" => 1359
              "Ancho" => 1500
              "Tamanyo" => 766559
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0015"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A&#44; Panoramic view &#40;hematoxylin-eosin&#41; of a fibrous hamartoma&#46; B&#44; C&#44; and D&#44; Higher-magnification view showing bundles and whorls of fibroblastic and immature mesenchymal tissue&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "L&#46; Martos-Cabrera, R&#46; Sampedro-Ruiz, Y&#46;C P&#233;rez-Gonz&#225;lez, T&#46; Mentzel, M&#46; Llamas-Velasco"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Martos-Cabrera"
            ]
            1 => array:2 [
              "nombre" => "R&#46;"
              "apellidos" => "Sampedro-Ruiz"
            ]
            2 => array:2 [
              "nombre" => "Y&#46;C"
              "apellidos" => "P&#233;rez-Gonz&#225;lez"
            ]
            3 => array:2 [
              "nombre" => "T&#46;"
              "apellidos" => "Mentzel"
            ]
            4 => array:2 [
              "nombre" => "M&#46;"
              "apellidos" => "Llamas-Velasco"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020305512"
        "doi" => "10.1016/j.ad.2020.12.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020305512?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021001463?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000006/v1_202106020933/S1578219021001463/v1_202106020933/en/main.assets"
  ]
  "itemAnterior" => array:20 [
    "pii" => "S1578219021001499"
    "issn" => "15782190"
    "doi" => "10.1016/j.adengl.2021.03.012"
    "estado" => "S300"
    "fechaPublicacion" => "2021-06-01"
    "aid" => "2581"
    "copyright" => "AEDV"
    "documento" => "article"
    "crossmark" => 1
    "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/"
    "subdocumento" => "rev"
    "cita" => "Actas Dermosifiliogr. 2021;112:503-15"
    "abierto" => array:3 [
      "ES" => true
      "ES2" => true
      "LATM" => true
    ]
    "gratuito" => true
    "lecturas" => array:1 [
      "total" => 0
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review</span>"
      "titulo" => "Janus Kinase Inhibitors in Dermatology&#58; Part 1 &#8212; General Considerations and Applications in Vitiligo and Alopecia Areata"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "503"
          "paginaFinal" => "515"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Inhibidores de JAK&#58; usos en dermatolog&#237;a&#46; Parte 1&#58; generalidades&#44; aplicaciones en vit&#237;ligo y en alopecia areata"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:8 [
          "identificador" => "fig0005"
          "etiqueta" => "Figure 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 2086
              "Ancho" => 3175
              "Tamanyo" => 249080
            ]
          ]
          "detalles" => array:1 [
            0 => array:3 [
              "identificador" => "at0005"
              "detalle" => "Figure "
              "rol" => "short"
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">JAK&#47;STAT pathway and mechanism of action of JAK inhibitors&#46;</p> <p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A&#44; JAK&#47;STAT pathway&#46; The cytokine binds to the receptor&#44; thus activating JAK proteins via phosphorylation&#46; The activated JAK protein phosphorylates the STAT protein&#44; in turn activating it&#46; Activated STAT is translocated to the nucleus&#46; Activated STAT protein acts as a transcription factor and binds to DNA&#44; thus regulating the transcription of a wide variety of genes and affecting cell growth and apoptosis&#46; B&#44; Mechanism of action of JAK inhibitors&#46; The inhibitors bind to the binding site of adenosine triphosphate of the JAK dimer&#44; thus preventing autophosphorylation and activation&#46; Similarly&#44; without activation of JAK&#44; the protein STAT cannot be activated or translocated to the nucleus&#44; resulting in reduced transcription of proinflammatory genes&#46; Figure generated with the assistance of Biorender&#46;com&#46; JAK indicates Janus kinase&#59; JAKi&#44; JAK inhibitor&#59; STAT&#44; signal transducer and activator of transcription&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "C&#46; Garcia-Melendo, X&#46; Cubir&#243;, L&#46; Puig"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "C&#46;"
              "apellidos" => "Garcia-Melendo"
            ]
            1 => array:2 [
              "nombre" => "X&#46;"
              "apellidos" => "Cubir&#243;"
            ]
            2 => array:2 [
              "nombre" => "L&#46;"
              "apellidos" => "Puig"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S0001731020305548"
        "doi" => "10.1016/j.ad.2020.12.003"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020305548?idApp=UINPBA000044"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021001499?idApp=UINPBA000044"
    "url" => "/15782190/0000011200000006/v1_202106020933/S1578219021001499/v1_202106020933/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Practical Dermatology</span>"
    "titulo" => "Safety in Dermatologic Procedures&#58; Hypertensive Crises and Potentially Fatal Arrhythmias"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "516"
        "paginaFinal" => "519"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "P&#46; Rodr&#237;guez-Jim&#233;nez, R&#46; Sampedro-Ruiz, I&#46; Imaz, P&#46; Chicharro"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "P&#46;"
            "apellidos" => "Rodr&#237;guez-Jim&#233;nez"
            "email" => array:1 [
              0 => "pedro.rodriguez.jimenez90@gmail.com"
            ]
            "referencia" => array:3 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
              2 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "R&#46;"
            "apellidos" => "Sampedro-Ruiz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "I&#46;"
            "apellidos" => "Imaz"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "P&#46;"
            "apellidos" => "Chicharro"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:3 [
          0 => array:3 [
            "entidad" => "Servicio de Dermatolog&#237;a&#44; Hospital Universitario La Princesa&#44; Madrid&#44; Spain"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Cl&#237;nica Dermatol&#243;gica Internacional&#44; Madrid&#44; Spain"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Anestesiolog&#237;a y Reanimaci&#243;n&#44; Hospital Universitario La Princesa&#44; Madrid&#44; Spain"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Seguridad en procedimientos dermatol&#243;gicos&#58; crisis hipertensiva y arritmias potencialmente malignas"
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">The incidence of intraoperative hypertensive crises is unknown&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a> Intraoperative arrhythmias affect up to 70&#46;2&#37; of patients who undergo surgery under general anesthetic&#44; but only 1&#46;6&#37; require treatment&#46; Prevalence with the use of local anesthesia is unknown&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">As dermatologic surgeons often perform long surgeries using local anesthetic alone&#44; they should be familiar with the basic management of 2 potentially severe complications&#58; hypertensive crises and intraoperative arrhythmias&#46;</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Hypertensive Crises in the Operating Theater</span><p id="par0015" class="elsevierStylePara elsevierViewall">Intraoperative hypertension will be recognized by monitoring the patient&#46; It may present only as profuse arteriolar bleeding or the patient may complain of cold sweating&#44; headache&#44; or nervousness&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">In the event of higher numbers with repercussions for the target organ&#44; the patient may present neurologic abnormality due to acute cerebrovascular accident&#44; dyspnea due to acute pulmonary edema&#44; or severe chest pain due to acute coronary or aortic syndrome&#46; Acute renal failure is usually asymptomatic&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Given the clinical signs and symptoms described&#44; we can differentiate between the following&#58;<ul class="elsevierStyleList" id="lis0005"><li class="elsevierStyleListItem" id="lsti0005"><span class="elsevierStyleLabel">1</span><p id="par0030" class="elsevierStylePara elsevierViewall">Hypertensive urgency&#58; significant spike in blood pressure &#40;BP&#41; &#40;most commonly used numbers&#58; BP&#8239;&#62;&#8239;180&#47;110&#8239;mmHg&#41; without target-organ dysfunction&#46; This is often a hypertension pseudocrisis due to pain or anxiety&#46;</p></li><li class="elsevierStyleListItem" id="lsti0010"><span class="elsevierStyleLabel">2</span><p id="par0035" class="elsevierStylePara elsevierViewall">Hypertensive emergency&#58; BP&#8239;&#62;&#8239;180&#47;110&#8239;mmHg&#41; with progressive target-organ damage&#44; requiring immediate reduction&#46;</p></li></ul></p><p id="par0040" class="elsevierStylePara elsevierViewall">The most frequent causes of both types of crisis are anesthetic induction&#44; sympathetic stimulus due to pain or hypothermia&#44; prolonged hypoxia&#44; excess fluid therapy&#44; or suspension of chronic antihypertensive medication &#40;a major and preventable cause that must be taken into account&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#8211;5</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">How to Prevent It</span><p id="par0045" class="elsevierStylePara elsevierViewall">The dermatologist must tell patients not to suspend their antihypertensive medication unless expressly ordered to do so by the anesthesiologist&#44; especially in the case of &#946;-blockers&#44; due to the excessive risk of a rebound effect&#46; Treatment with the drugs should also not be instated in the days prior to surgery&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Furthermore&#44; it is potentially helpful for patients to empty their bladder before surgery&#44; as this has been linked to a drop in blood pressure of a mean of 15&#8239;mmHg&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">How to Treat It</span><p id="par0055" class="elsevierStylePara elsevierViewall">In hypertensive emergencies&#44; reducing BP excessively rapidly is not recommended in order to prevent ischemic injury to vascular beds adapted to high pressure&#46; In general&#44; the objective should be to reduce pressure by between 10&#37; and 15&#37; in the first hour and by a further 5&#37;-15&#37; in the following 23&#8239;hours &#40;initial goal&#44; &#60;180&#47;120&#8239;mmHg and then 160&#47;110&#8239;mmHg&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">In hypertensive urgencies&#44; the pressure should be reduced over a matter of days and treatment should begin only if the high blood pressure involves increased surgical morbidity&#44; such as profuse bleeding that prevents surgery from continuing&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">The basic recommended antihypertensive drugs are shown in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; Captopril is the drug of choice for the dermatologist due to its safety profile and simplicity&#46; Nifedipine and amlodipine&#44; calcium-channel blockers that are traditionally used&#44; are the second line of choice in this context due to the risk of coronary or cerebral steal due to sudden peripheral vasodilation and are more commonly used as recue therapy&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0070" class="elsevierStylePara elsevierViewall">Before prescribing an antihypertensive drug&#44; analgesia with paracetamol &#40;1&#8239;g IV&#41; or metamizole &#40;2&#8239;g IV&#41; should be considered&#46; Intravenous metamizole is preferred due to its hypotensive side effect when administered via this route&#46; Moreover&#44; in patients identified as suffering from anxiety&#44; sublingual administration of 1-2&#8239;mg of lorazepam may be considered&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">The most important points in terms of prevention and treatment are shown in <a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Intraoperative Arrhythmias</span><p id="par0080" class="elsevierStylePara elsevierViewall">Monitoring the patient during surgery is essential to recognizing this complication&#46; We must become accustomed to monitoring&#44; especially elderly patients&#44; who are the subjects of most of our interventions&#46; Whenever possible&#44; a 12-lead electrocardiogram must be performed in patients with an abnormal heart rate&#46;</p><p id="par0085" class="elsevierStylePara elsevierViewall">Monitoring is essential in the event of an arrhythmia in order to determine whether the patient is hemodynamically stable &#40;asymptomatic&#41; or unstable &#40;perspiring&#44; with abnormal level of alertness&#44; dyspnea&#44; chest pain&#44; shock&#41;&#46;</p><p id="par0090" class="elsevierStylePara elsevierViewall">In the event of signs of instability&#44; the anesthesiologist must be notified immediately&#44; and the team should be prepared for a potential cardiopulmonary resuscitation&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">Asymptomatic bradycardia &#40;heart rate&#8239;&#60;&#8239;60&#8239;bpm&#41; does not require treatment&#44; but patients should always be checked to ensure they are alert and responsive&#46;</p><p id="par0100" class="elsevierStylePara elsevierViewall">The first step in clinically stable patients with tachycardia &#40;heart rate&#8239;&#62;&#8239;100&#8239;bpm&#41; ist to measure the width of the QRS complex&#46; A QRS measuring 120&#8239;ms &#40;3 small squares on the electrocardiogram&#41; or more is considered to be wide&#46;</p><p id="par0105" class="elsevierStylePara elsevierViewall">A normal upright P wave preceding every QRS complex indicates a sinus tachycardia&#44; probably in reaction to the operative setting &#40;anxiety&#44; pain&#44; etc&#46;&#41;&#46; This may be managed in the same way as hypertensive pseudocrises &#40;analgesia&#44; anxiolytics&#44; etc&#46;&#41;&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">If the tachycardia is not a sinus tachycardia&#44; safe action that may help in some narrow-QRS tachycardias involves vagal maneuvers &#40;forced Valsalva maneuver&#44; unilateral carotid massage&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">These actions cause complete atrioventricular block for a few moments&#44; which sometimes returns the patient to a sinus rhythm in some cases of atrioventricular-nodal reentrant tachycardia&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0120" class="elsevierStylePara elsevierViewall">Wide QRS tachycardias may be considered to be malignant arrhythmias unless proven otherwise&#44; especially if the patient has a history of ischemic heart disease&#46; These tachycardias include ventricular tachycardia and ventricular fibrillation&#46; Thus&#44; the anesthesiologist should be notified to perform an assessment in the case of a wide QRS tachycardia&#44; even if the patient is asymptomatic&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">It should be remembered&#44; however&#44; that a wide QRS does not always mean a malignant arrhythmia&#44; as any tachycardia in a patient with a prior bundle branch block will be seen as a wide QRS complex&#59; hence the importance of determining the baseline electrocardiogram of the patient&#46; Prevention and treatment of potentially malignant arrhythmias in the operating theater are shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Conclusion</span><p id="par0130" class="elsevierStylePara elsevierViewall">As final practical recommendations&#44; the authors advise the following&#58;<ul class="elsevierStyleList" id="lis0010"><li class="elsevierStyleListItem" id="lsti0015"><span class="elsevierStyleLabel">&#8226;</span><p id="par0135" class="elsevierStylePara elsevierViewall">Remember dosages and use of just a few drugs &#40;basically captopril and atropine&#41; and keep them at hand&#46;</p></li><li class="elsevierStyleListItem" id="lsti0020"><span class="elsevierStyleLabel">&#8226;</span><p id="par0140" class="elsevierStylePara elsevierViewall">Ideally&#44; monitor the patient and take peripheral blood in all surgical interventions&#46;</p></li><li class="elsevierStyleListItem" id="lsti0025"><span class="elsevierStyleLabel">&#8226;</span><p id="par0145" class="elsevierStylePara elsevierViewall">Know the drugs available&#44; theater personnel&#44; and the location of the specialist in anesthesiology and reanimation&#46;</p></li></ul></p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conflicts of Interest</span><p id="par0150" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:12 [
        0 => array:3 [
          "identificador" => "xres1519013"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec1377515"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres1519014"
          "titulo" => "Resumen"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0010"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec1377516"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Hypertensive Crises in the Operating Theater"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "How to Prevent It"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "How to Treat It"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Intraoperative Arrhythmias"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Conclusion"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Conflicts of Interest"
        ]
        10 => array:2 [
          "identificador" => "xack533631"
          "titulo" => "Acknowledgments"
        ]
        11 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2020-10-23"
    "fechaAceptado" => "2021-01-13"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec1377515"
          "palabras" => array:3 [
            0 => "Dermatologic surgery"
            1 => "Hypertension"
            2 => "Arrhythmias"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec1377516"
          "palabras" => array:3 [
            0 => "Cirug&#237;a dermatol&#243;gica"
            1 => "Hipertensi&#243;n"
            2 => "Arritmias"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">As dermatologic surgeons often have to perform long surgeries with local anesthetic only&#44; they should be familiar with the fundamentals of how to manage 2 potentially serious complications&#58; Hypertensive crises and intraoperative arrhythmias&#46;</p><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Hypertensive crises can be classified as 1&#41; hypertensive urgencies&#44; characterized by a significant spike in blood pressure &#40;&#62;180&#47;110&#8239;mmHg&#41; without target-organ dysfunction or 2&#41; hypertensive emergencies&#44; characterized by a blood pressure above 180&#47;110&#8239;mmHg with progressive target-organ damage&#46; In emergencies&#44; the blood pressure needs to be reduced immediately whereas in urgencies the goal is to reduce it over several days&#46; Care must still be taken not to reduce the blood pressure excessively rapidly in emergencies&#44; however&#44; to avoid ischemic injury to vascular beds that have adapted to a high blood pressure&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">We recommend that dermatologic surgeons use captopril in hypertensive emergencies because of its safety profile and ease of use&#46; Asymptomatic intraoperative bradycardia does not require treatment&#44; but patients should always be checked to ensure they are alert and responsive&#46; The first step in clinically stable patients with tachycardia is to measure the width of the QRS complex and notify the anesthetist when this is wide&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Dermatologic surgeons should also be familiar with the drugs available in the operating room&#44; ensure that they are easily accessible&#44; and identify the most essential ones so they can familiarize themselves with indications and dosage&#46; Patients should be monitored throughout the operation&#44; and material to secure a peripheral intravenous line should be prepared in case of need&#46; Finally&#44; the dermatologic surgeon should know all the staff working in the operating room and be able to locate the specialist in anesthesia and resuscitation&#46;</p></span>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Es importante para el cirujano dermatol&#243;gico&#44; que en muchas ocasiones realiza cirug&#237;as prolongadas con el uso exclusivo de anestesia local&#44; conocer el manejo b&#225;sico de dos complicaciones potencialmente graves&#58; las crisis hipertensivas y las arritmias intraoperatorias&#46;</p><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Respecto a las crisis hipertensivas&#44; diferenciamos entre urgencia hipertensiva&#58; elevaci&#243;n importante de la tensi&#243;n arterial &#40;&#62;180&#47;110&#8239;mm&#41; sin disfunci&#243;n de &#243;rgano diana y emergencia hipertensiva&#58; TA&#8239;&#62;&#8239;180&#47;110&#8239;mm Hg con da&#241;o progresivo de &#243;rgano diana y que requiere de su reducci&#243;n inmediata&#46; En la primera el objetivo ser&#225; descender la TA en d&#237;as y no suele requerir tratamiento urgente&#44; mientras que&#44; en la emergencia hipertensiva&#44; no se recomienda descender la TA excesivamente r&#225;pido para evitar da&#241;o isqu&#233;mico en lechos vasculares adaptados a una TA elevada&#46; De elecci&#243;n para el dermat&#243;logo por su perfil de seguridad y sencillez en la emergencia hipertensiva es el captopril&#46; En cuanto a las arritmias&#58; la bradicardia asintom&#225;tica no precisar&#225; de tratamiento&#44; pero siempre comprobaremos que el paciente se encuentra alerta y orientado&#46; En el caso de las taquicardias en las que el paciente est&#233; estable&#44; el siguiente paso ser&#237;a medir la anchura del complejo QRS y si est&#233; es ancho avisar al anestesista&#46;</p><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Se recomienda conocer los f&#225;rmacos disponibles en el quir&#243;fano&#44; tenerlos en lugar accesible y elegir los imprescindibles para conocer su uso y dosis&#46; Idealmente monitorizar y tener preparado el poder tomar v&#237;a perif&#233;rica en todas las intervenciones en quir&#243;fano&#44; as&#237; como conocer a todo el personal de quir&#243;fano y la localizaci&#243;n del especialista en anestesia y reanimaci&#243;n</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Rodr&#237;guez-Jim&#233;nez P&#44; Sampedro-Ruiz R&#44; Imaz I&#44; Chicharro P&#46; Seguridad en procedimientos dermatol&#243;gicos&#58; crisis hipertensiva y arritmias potencialmente malignas&#46; Actas Dermosifiliogr&#46; 2021&#59;112&#58;516&#8211;519&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:8 [
        "identificador" => "tbl0005"
        "etiqueta" => "Table 1"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0005"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Captopril &#40;angiotensin-converting enzyme-2 inhibitor&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Reduces BP without reflex tachycardia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Dosage&#58; 25&#8239;mg oral or sublingual &#40;effect in 15-20&#8239;min&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Long-lasting effect &#40;6&#8239;h&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Contraindications&#58; angioedema and pregnancy&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Furosemide&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Loop diuretic&#58; reduces BP by eliminating sodium and water by means of a vasodilating effect of unknown origin&#46; Care should be taken when used in the elderly due to the possibility of prolonged orthostatic hypotension due to water depletion&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Dosage&#58; 40&#8239;mg oral or 20&#8239;mg IV&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Rapid effect &#40;15&#8239;min IV&#47;1&#8239;h oral&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#8226; Contraindications&#58; allergy&#44; anuria&#44; and hypotension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2608367.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Antihypertensive Drugs Most Commonly Used in Hypertensive Crises&#46;</p>"
        ]
      ]
      1 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0010"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:2 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevention of Hypertensive Crises&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ideally&#44; perform in all patients in preanesthesia consultation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Do not stop antihypertensive medication &#40;dermatology&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Before beginning surgery&#44; identify any treatment transgressions or modifications&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ask patients to empty their bladder before surgery&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Check for factors that may cause pseudocrises&#44; such as anxiety and pain&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Monitor and cannulate a peripheral intravenous catheter in patients undergoing long surgeries or have a past troublesome personal history &#40;prior sincopes&#44; anxiety&#46;&#46;&#41;&#46; Otherwise&#44; be ready for cannulating if necessary&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2608368.png"
              ]
            ]
            1 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Treatment of Hypertensive Crises&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Confirm hypertensive crisis &#40;BP&#8239;&#62;&#8239;180&#47;110&#41; with 3 measurements using an appropriate cuff&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">If it is not a hypertensive crisis and there is no intraoperative morbidity&#44; consider not treating&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Consider treatment with 2 g IV metamizole or 1&#8239;mg sublingual lorazepam in patients with pain or anxiety&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Initial therapy&#58; captopril &#40;25&#8239;mg&#41;&#44; preferably oral or sublingual after chewing &#40;less desirable&#44; erratic effect and more sudden drop in BP&#41;&#58; effect in 15-30&#8239;min without reflex tachycardia&#46; Long-lasting effect &#40;6 hours&#41;&#46; Dose can be repeated every 15-30 minutes &#40;do not exceed 150&#8239;mg&#41;&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">If the patient is resistant to the above measures and requires monitoring &#8594; notify anesthesiologist for use of IV drugs &#8594; labetalol 10 mg&#47;urapidil 25 mg&#47;furosemide 20&#8239;mg&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2608369.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Prevention and Treatment of Hypertensive Crises&#46;</p>"
        ]
      ]
      2 => array:8 [
        "identificador" => "tbl0015"
        "etiqueta" => "Table 3"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0015"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:1 [
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevention of Potentially Malignant Arrhythmias&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Ideally&#44; perform in all patients in preanesthesia consultation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Determine prior arrhythmias&#44; abnormal electrocardiographic results&#44; or electrolyte abnormalities&#44; or whether the patient has undergone procedures under local anesthetic safely&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Monitor and take peripheral blood&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " colspan="1" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Treatment of Potentially Malignant Arrhythmias&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Symptomatic bradycardia &#40;&#60;50&#8239;bpm&#41; &#8594; atropine 0&#46;5-1&#8239;mg IV or subcutaneous&#46; &#40;avoid doses below 0&#46;01&#8239;mg&#47;kg to prevent reflex bradycardia&#41;&#59; may be repeated every 3 minutes up to 3&#8239;g &#8594; notify anesthesiologist for transcutaneous pacemaker or vasoactive drugs if no improvement and for monitoring if patient recovers&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Narrow QRS tachycardia &#8594; attempt vagal maneuvers &#8594; notify anesthesiologist&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Wide QRS tachycardia &#8594; notify cardiopulmonary reanimation team immediately and prepare for maneuvers&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2608366.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Prevention and Treatment of Potentially Malignant Arrhythmias&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:7 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Perioperative hypertension management"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Varon"
                            1 => "P&#46;E&#46; Marik"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.2147/vhrm.s2471"
                      "Revista" => array:6 [
                        "tituloSerie" => "Vasc Health Risk Manag&#46;"
                        "fecha" => "2008"
                        "volumen" => "4"
                        "paginaInicial" => "615"
                        "paginaFinal" => "627"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18827911"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Arritmias card&#237;acas en anestesia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "P&#46; Luna-Ortiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rev Mex Anestesiol&#46;"
                        "fecha" => "2017"
                        "volumen" => "40"
                        "numero" => "Jun 15"
                        "paginaInicial" => "440"
                        "paginaFinal" => "448"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Manual de diagn&#243;stico y terap&#233;utica m&#233;dica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Suarez Pita"
                            1 => "J&#46;C&#46; Vargas Romero"
                            2 => "J&#46; Salas Jarque"
                            3 => "I&#46; Losada Galv&#225;n"
                            4 => "B&#46; De Miguel Campo"
                            5 => "P&#46;M&#46; Catal&#225;n Mart&#237;n"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:4 [
                        "edicion" => "8&#46;<span class="elsevierStyleSup">a</span> edici&#243;n"
                        "fecha" => "2017"
                        "editorial" => "MSD"
                        "editorialLocalizacion" => "Madrid"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evaluation and management of hypertension in the perioperative period of Mohs micrographic surgery&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "R&#46;J&#46; Larson"
                            1 => "J&#46; Aylward"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/dsu.0000000000000012"
                      "Revista" => array:6 [
                        "tituloSerie" => "Dermatol Surg&#46;"
                        "fecha" => "2014"
                        "volumen" => "40"
                        "paginaInicial" => "603"
                        "paginaFinal" => "609"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24852463"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Crisis hipertensivas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Caldevilla Bernardo"
                            1 => "J&#46; Mart&#237;nez P&#233;rez"
                            2 => "L&#46;M&#46; Artigao Rodenas"
                            3 => "J&#46;A&#46; Divis&#243;n Garrote"
                            4 => "J&#46;A&#46; Carbayo-Herencia"
                            5 => "J&#46; Mass&#243; Orozco"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Cl&#237;n Med Fam&#46;"
                        "fecha" => "2008"
                        "volumen" => "2"
                        "paginaInicial" => "236"
                        "paginaFinal" => "243"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Sympathetic activity and blood pressure increases with bladder distension in humans"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Fagius"
                            1 => "S&#46; Karhuvaara"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1161/01.hyp.14.5.511"
                      "Revista" => array:6 [
                        "tituloSerie" => "Hypertension&#46;"
                        "fecha" => "1989"
                        "volumen" => "14"
                        "paginaInicial" => "511"
                        "paginaFinal" => "517"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2807512"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "ESC Scientific Document Group&#46; 2019 ESC Guidelines for the management of patients with supraventricular tachycardia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Brugada"
                            1 => "D&#46;G&#46; Katritsis"
                            2 => "E&#46; Arbelo"
                            3 => "F&#46; Arribas"
                            4 => "J&#46; Bax"
                            5 => "C&#46; Blomstr&#246;m-Lundqvist"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/eurheartj/ehz467"
                      "Revista" => array:6 [
                        "tituloSerie" => "Eur Heart J&#46;"
                        "fecha" => "2020"
                        "volumen" => "41"
                        "paginaInicial" => "655"
                        "paginaFinal" => "720"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/31504425"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
    "agradecimientos" => array:1 [
      0 => array:4 [
        "identificador" => "xack533631"
        "titulo" => "Acknowledgments"
        "texto" => "<p id="par0155" class="elsevierStylePara elsevierViewall">The authors would like to thank Dr&#46; Emilio del R&#237;o and Dr&#46; Garc&#237;a Doval for the original idea for this series and Dr&#46; Juan S&#225;nchez Estella for his bibliographic contribution&#46;</p>"
        "vista" => "all"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/15782190/0000011200000006/v1_202106020933/S1578219021001542/v1_202106020933/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "6151"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Practical Dermatology"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000006/v1_202106020933/S1578219021001542/v1_202106020933/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021001542?idApp=UINPBA000044"
]