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(b) Lesión irregular atípica, pigmentada, de color marrón oscuro-negro con un velo azul-blanquecino en el centro, rodeado de eritema y con escasos vasos punteados dentro del halo. (c) Aspecto histopatológico del fenómeno de Meyerson en un melanoma. Proliferación melanocítica confluente atípica intraepidérmica. Espongiosis leve, acantosis epidérmica e infiltrado celular inflamatorio crónico. (Tinción hematoxilina-eosina; aumento original: x20).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "X. Calderón-Castrat, A. Conde-Ferreirós, M. Yuste-Chaves, A. Santos-Briz" "autores" => array:4 [ 0 => array:2 [ "nombre" => "X." "apellidos" => "Calderón-Castrat" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Conde-Ferreirós" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Yuste-Chaves" ] 3 => array:2 [ "nombre" => "A." 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B, <span class="elsevierStyleItalic">S lugdunensis</span> colony growing on blood agar.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A.J. García-Malinis, A. Milagro, L. Torres Sopena, Y. Gilaberte" "autores" => array:4 [ 0 => array:2 [ "nombre" => "A.J." "apellidos" => "García-Malinis" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Milagro" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Torres Sopena" ] 3 => array:2 [ "nombre" => "Y." "apellidos" => "Gilaberte" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731020304208" "doi" => "10.1016/j.ad.2019.05.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731020304208?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219021000044?idApp=UINPBA000044" "url" => "/15782190/0000011200000003/v1_202103020923/S1578219021000044/v1_202103020923/en/main.assets" ] "itemAnterior" => array:20 [ "pii" => "S1578219021000032" "issn" => "15782190" "doi" => "10.1016/j.adengl.2021.01.003" "estado" => "S300" "fechaPublicacion" => "2021-03-01" "aid" => "2495" "copyright" => "AEDV" "documento" => "simple-article" "crossmark" => 1 "licencia" => "http://creativecommons.org/licenses/by-nc-nd/4.0/" "subdocumento" => "crp" "cita" => "Actas Dermosifiliogr. 2021;112:257-8" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Case for Diagnosis</span>" "titulo" => "Congenital Scalp Lesion" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "257" "paginaFinal" => "258" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Una lesión congénita en el cuero cabelludo" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 672 "Ancho" => 1000 "Tamanyo" => 284792 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Histopathological features of the lesion. 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Calderón-Castrat, A. Conde-Ferreirós, M. Yuste-Chaves, A. Santos-Briz" "autores" => array:4 [ 0 => array:4 [ "nombre" => "X." "apellidos" => "Calderón-Castrat" "email" => array:1 [ 0 => "xcalderoncastrat@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Conde-Ferreirós" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "M." "apellidos" => "Yuste-Chaves" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "A." "apellidos" => "Santos-Briz" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Departamento de Dermatología, IMED-ELCHE Hospital, Alicante, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Dermatología, Hospital Universitario de Salamanca, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Departamento de Patología, Hospital Universitario de Salamanca, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La bandera roja: fenómeno de Meyerson en el melanoma maligno" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1355 "Ancho" => 2500 "Tamanyo" => 394008 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Central pigmented lesion and surrounding eczematous halo. (b) Dermoscopy revealing central pigmented dark brown-black atypical and irregular lesion with a blue-white veil in the center surrounded by erythema and scarce dotted vessels within the halo. (c) Histopathologic appearance of Meyerson phenomenon within a melanoma. Intraepidermal atypical, confluent melanocytic proliferation. Mild spongiosis, epidermal acantosis and chronic inflammatory cell infiltrate. (Hematoxylin-eosin stain; original magnification: ×20).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case presentation</span><p id="par0005" class="elsevierStylePara elsevierViewall">A 65-year-old woman was referred to our Department of Dermatology for a pruriginous lesion on her abdomen that failed to show improvement after 1-month of topical corticosteroid treatment. She presented with a congenital nevus, that 2 months prior consultation developed a red, scaly and pruritic halo. Physical examination showed a pigmented brown-black, 1.6 cm, slightly elevated lesion on the left flank surrounded by an erythematous scaly halo (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>(a)). Dermoscopic appearance revealed an atypical, pigmented, dark brown-black irregular lesion with a blue-white veil in the center surrounded by erythema and scarce dotted vessels within the halo (<a class="elsevierStyleCrossRef" href="#fig0005">Fig.1</a>(b)). Histopathological analysis demonstrated a superficial spreading melanoma with radial and vertical growth phase, Clark Level IV, Breslow depth of 0,98 mm. An acanthotic epidermis with discrete spongiosis and intense chronic inflammatory component was also observed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig.1</a>(c)). After the initial excision, the eczematous halo was soon resolved. Further imaging studies failed to show signs of metastasic disease, followed by a 1-cm surgical margin and selective sentinel lymph node biopsy that resulted negative.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Diagnosis</span><p id="par0010" class="elsevierStylePara elsevierViewall">Clinical, dermoscopic and histological correlation established the diagnosis of malignant melanoma with Meyerson phenomenon.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Commentary</span><p id="par0015" class="elsevierStylePara elsevierViewall">Meyerson phenomenon (MP) refers to a localized eczematous eruption classically associated with benign melanocytic nevi, hence the denomination Meyerson nevus.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Considered rare, but possibly underdiagnosed, MP has generally reflected a sign of banal lesions<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> including dermatofibromas,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> seborrheic keratosis,<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> keratosis stucco<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> and angiokeratoma,<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> among others. However, dysplasic nevi, and few cases of basal cell and squamous carcinomas have also been described.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> Only anecdotal reports of melanoma in situ have been reported in medical literature.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Our case particularly reveals an invasive malignant melanoma.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Our case highlights that lesions targeted by the MP are not necessarily benign and thus careful dermoscopic examination is warranted to prevent overlooking malignant melanocytic lesions.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:4 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Case presentation" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Diagnosis" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Commentary" ] 3 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Calderón-Castrat X, Conde-Ferreirós A, Yuste-Chaves M, Santos-Briz A. La bandera roja: fenómeno de Meyerson en el melanoma maligno. Actas Dermosifiliogr. 2021;112:259–260.</p>" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1355 "Ancho" => 2500 "Tamanyo" => 394008 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Figure " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">(a) Central pigmented lesion and surrounding eczematous halo. (b) Dermoscopy revealing central pigmented dark brown-black atypical and irregular lesion with a blue-white veil in the center surrounded by erythema and scarce dotted vessels within the halo. (c) Histopathologic appearance of Meyerson phenomenon within a melanoma. Intraepidermal atypical, confluent melanocytic proliferation. Mild spongiosis, epidermal acantosis and chronic inflammatory cell infiltrate. (Hematoxylin-eosin stain; original magnification: ×20).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:5 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A peculiar papulosquamous eruption involving pigmented nevi" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L.B. Meyerson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1971" "volumen" => "34" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Halo dermatitis around tumours" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E. Tegner" 1 => "A. Björnberg" 2 => "N. 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Kumar" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1440-0960.2010.00726.x" "Revista" => array:6 [ "tituloSerie" => "Australas J Dermatol" "fecha" => "2012" "volumen" => "53" "paginaInicial" => "145" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22571567" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Solitary angiokeratoma with Meyerson phenomenon" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A. Oliveira" 1 => "J. Cardoso" 2 => "I. Zalaudek" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2016.04.039" "Revista" => array:7 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2017" "volumen" => "76" "paginaInicial" => "S16" "paginaFinal" => "S18" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28087017" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0302283819301502" "estado" => "S300" "issn" => "03022838" ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Meyerson phenomenon as a component of melanoma in situ" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "E. Sezer" 1 => "E. Özturk Durmaz" 2 => "E. Çetin" 3 => "S. Şahin" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Dermatovenerol Croat" "fecha" => "2016" "volumen" => "24" "paginaInicial" => "81" "paginaFinal" => "82" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27149137" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011200000003/v1_202103020923/S157821902030384X/v1_202103020923/en/main.assets" "Apartado" => array:4 [ "identificador" => "19289" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Practical Dermoscopy" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011200000003/v1_202103020923/S157821902030384X/v1_202103020923/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821902030384X?idApp=UINPBA000044" ]
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2024 September | 148 | 49 | 197 |
2024 August | 215 | 71 | 286 |
2024 July | 206 | 57 | 263 |
2024 June | 178 | 55 | 233 |
2024 May | 156 | 63 | 219 |
2024 April | 148 | 35 | 183 |
2024 March | 145 | 46 | 191 |
2024 February | 141 | 51 | 192 |
2024 January | 141 | 51 | 192 |
2023 December | 119 | 49 | 168 |
2023 November | 163 | 43 | 206 |
2023 October | 126 | 32 | 158 |
2023 September | 123 | 47 | 170 |
2023 August | 96 | 35 | 131 |
2023 July | 109 | 56 | 165 |
2023 June | 90 | 39 | 129 |
2023 May | 117 | 43 | 160 |
2023 April | 69 | 48 | 117 |
2023 March | 137 | 59 | 196 |
2023 February | 115 | 47 | 162 |
2023 January | 73 | 41 | 114 |
2022 December | 95 | 47 | 142 |
2022 November | 72 | 41 | 113 |
2022 October | 79 | 41 | 120 |
2022 September | 94 | 51 | 145 |
2022 August | 97 | 54 | 151 |
2022 July | 50 | 45 | 95 |
2022 June | 42 | 49 | 91 |
2022 May | 142 | 49 | 191 |
2022 April | 167 | 31 | 198 |
2022 March | 164 | 50 | 214 |
2022 February | 117 | 54 | 171 |
2022 January | 112 | 55 | 167 |
2021 December | 88 | 50 | 138 |
2021 November | 97 | 48 | 145 |
2021 October | 103 | 78 | 181 |
2021 September | 83 | 52 | 135 |
2021 August | 96 | 76 | 172 |
2021 July | 75 | 27 | 102 |
2021 June | 65 | 39 | 104 |
2021 May | 59 | 54 | 113 |
2021 April | 82 | 78 | 160 |
2021 March | 78 | 64 | 142 |
2021 February | 27 | 28 | 55 |
2021 January | 31 | 29 | 60 |
2020 December | 12 | 14 | 26 |