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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Alopecia areata universalis &#40;AAU&#41; is a chronic disease that&#44; not only involves a physical discomfort&#44; but it can also entail a mental health problem due to its relapsing nature and a great impact in self-image&#46; In fact&#44; some studies showed that the likelihood of being attended in mental health services is higher in these patients&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Moreover&#44; a recent meta-analysis<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> found that alexithymia&#44; anxiety and depression are common in patients with AAU&#44; and authors encourage to refer these patients to specialist attention for a better management&#46; Regarding psychological impact&#44; new studies addressed consequences of living with AAU at different levels&#44; such as cognitive &#40;e&#46;g&#46; negative thoughts related to their hair and appearance&#44; hopelessness&#41;&#44; emotional &#40;e&#46;g&#46; sadness&#41;&#44; and behaviour &#40;e&#46;g&#46; a restricted life as part of social withdrawal&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Within other countries like UK&#44; collaboration between psychology and dermatology professionals is growing&#44; considering that psychological assessment and treatment should be part of the healthcare of dermatology patients&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> However&#44; despite being the medical assistance of these patients a prevalent phenomenon that greatly impacts our daily clinical practice&#44; very little information is available regarding psychological treatment of these issues&#46; That is&#44; literature is scarce regarding psychological treatments for AAU patients&#46; To our knowledge&#44; this is the first study that have addressed how a cognitive-behavioural therapy&#44; in a psychoeducative group setting&#44; can help in the clinical care of women with AAU&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In order to assess if the usefulness of this psychological intervention in these patients&#44; and to identify key elements that may allow us to improve our quality of assistance in this area&#44; we conducted a pilot study with a group of AAU patients that were followed-up at the Trichology Unit in the Hospital Ram&#243;n y Cajal&#44; Madrid&#46; The intervention consisted of nine fortnightly sessions in a psychoeducative group setting&#46; Cognitive-behavioural techniques were used&#44; such as problem-solving&#44; cognitive restructuring&#44; relaxation and social skills&#46; The impact on QoL&#44; sleep&#44; anxiety and alexithymia were measured using validated scales&#46; All statistical analyses were performed using a statistical software package &#40;IBM SPSS Statistics for Macintosh&#44; Version 21&#46;0&#44; released 2012&#59; IBM Corp&#46;&#44; Armonk&#44; NY&#44; USA&#41;&#46; To study significant difference between after and before intervention t-test and Pearson correlation coefficient were used&#46; All tests were 2-sided and statistical significance was considered with p&#8239;&#60;&#8239;0&#46;05&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">A total of 16 women diagnosed with AAU were included&#46; Their mean age was 45&#46;1 years &#40;range 24-64&#41;&#46; Pre-post treatment comparisons are given in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> in more detail&#46; Results showed an improvement in the QoL &#40;p&#8239;&#61;&#8239;0&#46;041&#41; and sleep &#40;p&#8239;&#60;&#8239;0&#46;01&#41;&#44; while a paradoxical increase was found in alexithymia &#40;p&#8239;&#61;&#8239;0&#46;025&#41;&#46; No other significant differences were found between the beginning and the end of the treatment&#46; Furthermore&#44; correlation tests were conducted between variables&#46; At the beginning&#44; the quality of sleep seemed to be related with anxiety &#40;r&#8239;&#61;&#8239;0&#46;660&#41;&#44; depression &#40;r&#8239;&#61;&#8239;0&#46;621&#41; and self-steem &#40;r&#8239;&#61;&#8239;0&#46;580&#41;&#46; At the end of treatment&#44; depression was also significantly related with QoL &#40;r&#8239;&#61;&#8239;0&#46;519&#41;&#44; whereas anxiety was associated with alexithymia &#40;0&#46;532&#41;&#44; as well as with depression &#40;r&#8239;&#61;&#8239;0&#46;599&#41; and self-steem &#40;r&#61; -0&#46;567&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">These results have several implications&#46; Firstly&#44; the psychological intervention seems to be effective to improve QoL and sleep in women with AA&#44; which are basic for the well-being of our patients&#46; Some authors stated that patients with AAU have multiple risk factors for mental health disorders&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> such as psychological distress and a significant degree of impairment in quality of life &#40;QoL&#46; Despite more research is needed to thoroughly study the association between QoL&#44; sleep quality and well-being in AAU patients&#44; it suggests that it is strongly encouraged to bear these variables in mind when treating patients with AAU&#46;The psychologist&#8217;s role in AAU patients is to improve the availability and use of personal resources and abilities to cope with their distress&#44; improving their personal&#44; social and family quality of life&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Furhermore&#44; additional measures such as IPDE might be useful to discriminate personality profiles that are associated with QoL and clinical course in AAU&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Secondly&#44; a modest improvement was observed in anxiety&#44; despite not being significant&#44; which might be explained for the little sample size and the restricted period of time&#46; Some improvements such as quality of sleep of little details regarding QoL in AA patients are easier to achieve faster than others which are more complex&#44; such as anxiety or depression&#44; which often need more than a few weeks to change&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Finally&#44; regarding the paradoxical increase found in alexithymia&#44; it might be part of the process of starting to recognize self-emotions&#46; Some patients may be still confused about emotions&#44; while others already know how to identify them&#44; how they feel but not how to express it&#46; Future studies may shed light in this issue&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Some limitations must be noted&#46; Our sample is exclusively composed of women&#44; so results cannot be generalized to male AAU patients and the sample size is very limited&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In conclusion&#44; our preliminar results show the positive impact of psychological interventions to improve AAU patients&#8217; QoL&#46; It supports the collaboration between psychologists and dermatologists to improve clinical management of dermatological disease&#46; These data will be useful for future studies regarding the impact of psychological intervention in patients with alopecia areata&#46;</p></span>"
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        "tabla" => array:2 [
          "leyenda" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">&#42;p&#8239;&#60;&#8239;0&#46;05&#59; &#42;&#42;p&#8239;&#60;&#8239;0&#46;01&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Variable&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">M&#8239;&#177;&#8239;DT&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CLINICAL FEATURES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#46;45&#8239;&#177;&#8239;18&#44;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Age of onset &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">15&#46;56&#8239;&#177;&#8239;12&#46;41&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Duration of the alopecia &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#46;00&#8239;&#177;&#8239;1&#46;85&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Number of treatments received&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;00&#8239;&#177;&#8239;8&#46;99&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PSYCHOLOGICAL FEATURES&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Quality of life &#40;<span class="elsevierStyleItalic">Dermatology Life Quality Index &#8211; DLQI</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;041&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#46;44&#8239;&#177;&#8239;5&#46;15&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;000&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Depression&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;20&#8239;&#177;&#8239;9&#46;47&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;<span class="elsevierStyleItalic">Beck Depression Inventory- BDI</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#46;20&#8239;&#177;&#8239;10&#46;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">State anxiety&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">57&#46;75&#8239;&#177;&#8239;29&#46;25&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;160&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;<span class="elsevierStyleItalic">State-trait Anxiety Inventory -STAI</span> &#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">48&#46;88&#8239;&#177;&#8239;23&#46;17&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Self-steem&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#46;86&#8239;&#177;&#8239;4&#46;09&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;426&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;<span class="elsevierStyleItalic">Rosenberg Self-esteem Scale - RSES</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">31&#46;00&#8239;&#177;&#8239;4&#46;96&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sleep&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#46;80&#8239;&#177;&#8239;6&#46;37&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;000&#42;&#42;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&#40;<span class="elsevierStyleItalic">Oviedo Sleep Questionnaire - OSQ</span>&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">0&#46;93&#8239;&#177;&#8239;0&#46;79&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Alexithymia&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">PRE&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">43&#46;93&#8239;&#177;&#8239;22&#46;85&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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Case and Research Letters
Impact of Psychological Intervention in Women with Alopecia Areata Universalis: a Pilot Study
Impacto de la intervención psicológica en mujeres con alopecia areata universal: un estudio piloto
A. Pascual-Sáncheza,
Corresponding author
, P. Fernández-Martína, D. Saceda-Corralob,c, S. Vañó-Galvánb,c
a Servicio de Psiquiatría, Hospital Ramón y Cajal, Madrid, Spain
b Departamento de Dermatología, Hospital Universitario Ramón y Cajal, Departamento de Medicina, Facultad de Medicina, Universidad de Alcalá, IRYCIS, Madrid, Spain
c Unidad de Tricología, Grupo de Dermatología Pedro Jaén, Madrid, Spain
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    "cabecera" => "<span class="elsevierStyleTextfn">Case and Research Letters</span>"
    "titulo" => "Impact of Psychological Intervention in Women with Alopecia Areata Universalis&#58; a Pilot Study"
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            "entidad" => "Departamento de Dermatolog&#237;a&#44; Hospital Universitario Ram&#243;n y Cajal&#44; Departamento de Medicina&#44; Facultad de Medicina&#44; Universidad de Alcal&#225;&#44; IRYCIS&#44; Madrid&#44; Spain"
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        "titulo" => "Impacto de la intervenci&#243;n psicol&#243;gica en mujeres con alopecia areata universal&#58; un estudio piloto"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Alopecia areata universalis &#40;AAU&#41; is a chronic disease that&#44; not only involves a physical discomfort&#44; but it can also entail a mental health problem due to its relapsing nature and a great impact in self-image&#46; In fact&#44; some studies showed that the likelihood of being attended in mental health services is higher in these patients&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Moreover&#44; a recent meta-analysis<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> found that alexithymia&#44; anxiety and depression are common in patients with AAU&#44; and authors encourage to refer these patients to specialist attention for a better management&#46; Regarding psychological impact&#44; new studies addressed consequences of living with AAU at different levels&#44; such as cognitive &#40;e&#46;g&#46; negative thoughts related to their hair and appearance&#44; hopelessness&#41;&#44; emotional &#40;e&#46;g&#46; sadness&#41;&#44; and behaviour &#40;e&#46;g&#46; a restricted life as part of social withdrawal&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Within other countries like UK&#44; collaboration between psychology and dermatology professionals is growing&#44; considering that psychological assessment and treatment should be part of the healthcare of dermatology patients&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> However&#44; despite being the medical assistance of these patients a prevalent phenomenon that greatly impacts our daily clinical practice&#44; very little information is available regarding psychological treatment of these issues&#46; That is&#44; literature is scarce regarding psychological treatments for AAU patients&#46; To our knowledge&#44; this is the first study that have addressed how a cognitive-behavioural therapy&#44; in a psychoeducative group setting&#44; can help in the clinical care of women with AAU&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">In order to assess if the usefulness of this psychological intervention in these patients&#44; and to identify key elements that may allow us to improve our quality of assistance in this area&#44; we conducted a pilot study with a group of AAU patients that were followed-up at the Trichology Unit in the Hospital Ram&#243;n y Cajal&#44; Madrid&#46; The intervention consisted of nine fortnightly sessions in a psychoeducative group setting&#46; Cognitive-behavioural techniques were used&#44; such as problem-solving&#44; cognitive restructuring&#44; relaxation and social skills&#46; The impact on QoL&#44; sleep&#44; anxiety and alexithymia were measured using validated scales&#46; All statistical analyses were performed using a statistical software package &#40;IBM SPSS Statistics for Macintosh&#44; Version 21&#46;0&#44; released 2012&#59; IBM Corp&#46;&#44; Armonk&#44; NY&#44; USA&#41;&#46; To study significant difference between after and before intervention t-test and Pearson correlation coefficient were used&#46; All tests were 2-sided and statistical significance was considered with p&#8239;&#60;&#8239;0&#46;05&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">A total of 16 women diagnosed with AAU were included&#46; Their mean age was 45&#46;1 years &#40;range 24-64&#41;&#46; Pre-post treatment comparisons are given in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> in more detail&#46; Results showed an improvement in the QoL &#40;p&#8239;&#61;&#8239;0&#46;041&#41; and sleep &#40;p&#8239;&#60;&#8239;0&#46;01&#41;&#44; while a paradoxical increase was found in alexithymia &#40;p&#8239;&#61;&#8239;0&#46;025&#41;&#46; No other significant differences were found between the beginning and the end of the treatment&#46; Furthermore&#44; correlation tests were conducted between variables&#46; At the beginning&#44; the quality of sleep seemed to be related with anxiety &#40;r&#8239;&#61;&#8239;0&#46;660&#41;&#44; depression &#40;r&#8239;&#61;&#8239;0&#46;621&#41; and self-steem &#40;r&#8239;&#61;&#8239;0&#46;580&#41;&#46; At the end of treatment&#44; depression was also significantly related with QoL &#40;r&#8239;&#61;&#8239;0&#46;519&#41;&#44; whereas anxiety was associated with alexithymia &#40;0&#46;532&#41;&#44; as well as with depression &#40;r&#8239;&#61;&#8239;0&#46;599&#41; and self-steem &#40;r&#61; -0&#46;567&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">These results have several implications&#46; Firstly&#44; the psychological intervention seems to be effective to improve QoL and sleep in women with AA&#44; which are basic for the well-being of our patients&#46; Some authors stated that patients with AAU have multiple risk factors for mental health disorders&#44;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> such as psychological distress and a significant degree of impairment in quality of life &#40;QoL&#46; Despite more research is needed to thoroughly study the association between QoL&#44; sleep quality and well-being in AAU patients&#44; it suggests that it is strongly encouraged to bear these variables in mind when treating patients with AAU&#46;The psychologist&#8217;s role in AAU patients is to improve the availability and use of personal resources and abilities to cope with their distress&#44; improving their personal&#44; social and family quality of life&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Furhermore&#44; additional measures such as IPDE might be useful to discriminate personality profiles that are associated with QoL and clinical course in AAU&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Secondly&#44; a modest improvement was observed in anxiety&#44; despite not being significant&#44; which might be explained for the little sample size and the restricted period of time&#46; Some improvements such as quality of sleep of little details regarding QoL in AA patients are easier to achieve faster than others which are more complex&#44; such as anxiety or depression&#44; which often need more than a few weeks to change&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Finally&#44; regarding the paradoxical increase found in alexithymia&#44; it might be part of the process of starting to recognize self-emotions&#46; Some patients may be still confused about emotions&#44; while others already know how to identify them&#44; how they feel but not how to express it&#46; Future studies may shed light in this issue&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Some limitations must be noted&#46; Our sample is exclusively composed of women&#44; so results cannot be generalized to male AAU patients and the sample size is very limited&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In conclusion&#44; our preliminar results show the positive impact of psychological interventions to improve AAU patients&#8217; QoL&#46; It supports the collaboration between psychologists and dermatologists to improve clinical management of dermatological disease&#46; These data will be useful for future studies regarding the impact of psychological intervention in patients with alopecia areata&#46;</p></span>"
    "pdfFichero" => "main.pdf"
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    "fechaRecibido" => "2019-08-27"
    "fechaAceptado" => "2019-12-02"
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        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Pascual-S&#225;nchez A&#44; Fern&#225;ndez-Mart&#237;n P&#44; Saceda-Corralo D&#44; Va&#241;&#243;-Galv&#225;n S&#46; Impacto de la intervenci&#243;n psicol&#243;gica en mujeres con alopecia areata universal&#58; un estudio piloto&#46; An Pediatr &#40;Barc&#41;&#46;2020&#46; <span class="elsevierStyleInterRef" id="intr0005" href="https://doi.org/10.1016/j.anpedi.2020.05.006">https&#58;&#47;&#47;doi&#46;org&#47;10&#46;1016&#47;j&#46;anpedi&#46;2020&#46;05&#46;006</span></p>"
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">M&#8239;&#177;&#8239;DT&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">p&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">24&#46;45&#8239;&#177;&#8239;18&#44;55&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Age of onset &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Duration of the alopecia &#40;years&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">4&#46;00&#8239;&#177;&#8239;1&#46;85&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">Number of treatments received&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">9&#46;00&#8239;&#177;&#8239;8&#46;99&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">0&#46;041&#42;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">&#40;<span class="elsevierStyleItalic">Beck Depression Inventory- BDI</span>&#41;&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">State anxiety&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">POST&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
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                  \t\t\t\t</td><td class="td" title="\n
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                      "titulo" => "Large-scale retrospective cohort study of psychological stress in patients with Alopecia Areata according to the frequency of intralesional steroid injection"
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                        0 => array:2 [
                          "etal" => false
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                            0 => "H&#46; Shinwon"
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                            2 => "K&#46; Tae-Gyun"
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Article information
ISSN: 15782190
Original language: English
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Idiomas
Actas Dermo-Sifiliográficas
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