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Practical Dermoscopy
When We Can’t See the Forest for the Trees
Cuando los árboles no dejan ver el bosque
A. Mateos-Mayo
Corresponding author
ana.mateosm@hotmail.com

Corresponding author.
, A. Sánchez-Herrero, J.A. Avilés-Izquierdo
Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain
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          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A&#44; Nodule on the scalp&#46; B&#44; Nodule in the area of the right scapula&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Case Description</span><p id="par0005" class="elsevierStylePara elsevierViewall">We present 2 cases that had previously been diagnosed as basal cell carcinoma based on the presence of arborizing vessels in dermoscopy&#46; The first involved a 49-year-old woman&#44; in whom the tumor was located on the scalp &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#44; and the second a 70-year-old woman&#44; in whom the tumor was located in the area of the right scapula &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">&#91;&#91;&#63;&#93;&#93;<span class="elsevierStyleBold">What is your diagnosis&#63;</span></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Comment</span><p id="par0015" class="elsevierStylePara elsevierViewall">In the first case&#44; dermoscopy revealed arborizing vessels on a flesh-colored background with peripheral nonspecific brown areas &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>A&#41;&#46; The patient was receiving treatment for disseminated carcinoma of the breast&#46; Biopsy confirmed the definitive diagnosis of skin metastasis resulting from mammary carcinoma&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">In the second case&#44; dermoscopy revealed peripherally distributed arborizing vessels surrounding a central ulcerated area with a central yellowish background &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>B&#41;&#46; Pressure released keratinizing material&#44; thus confirming the diagnosis of infundibular epidermal cyst&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Arborizing vessels&#44; also known as telangiectasias or &#8220;tree-like&#8221; vessels&#44; are defined morphologically as large-caliber structures that are intensely red in color and branch into finer secondary vessels&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">This type of vessel is one of the most characteristic dermatoscopic criteria of basal cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">The literature contains numerous cases of lesions that mimic basal cell carcinoma owing to the presence of arborizing vessels&#46; These include various types of adnexal tumors<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> and infundibular cysts&#44;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> as in the second case we report&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">A study on the presence of arborizing lesions in conditions other than basal cell carcinoma revealed that up to 46&#37; of lesions with arborizing vessels in dermoscopy were not basal cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> These lesions included various cystic tumors &#40;infundibular cyst&#44; digital mucous cyst&#44; milium&#41;&#44; noncystic tumors &#40;dermatofibroma&#44; hypertrophic scars&#44; intradermal nevi&#44; and xanthogranulomas&#41;&#44; and&#44; albeit less frequently&#44; nontumoral lesions such as necrobiosis lipoidica and morphea&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">The presence of arborizing vessels has also been described in some cases of skin metastasis from visceral tumors&#44; such as those affecting the colon or ovary&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> Skin metastases from breast cancer often present pigmented structures that mimic melanoma more than basal cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a></p><p id="par0050" class="elsevierStylePara elsevierViewall">While dermoscopy is very useful for increasing diagnostic accuracy&#44; excessive attention to detail can sometimes present us from seeing the whole picture&#44; as in the 2 cases we report&#46; In no cases is the presence of a single dermatoscopic structure sufficient to confirm a diagnosis&#46; Therefore&#44; the presence of arborizing vessels in dermoscopy of a lesion should point us to other diagnoses in addition to basal cell carcinoma and to alternative clinical or dermatoscopic findings that help to establish a diagnosis&#46;</p></span></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Mateos-Mayo A&#44; et al&#46; Cuando los &#225;rboles no dejan ver el bosque&#46; Actas Dermosifiliogr&#46; 2020&#59;111&#58;159&#8211;160&#46;</p>"
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