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Sentinel Lymph Node Biopsy
Biopsia selectiva del ganglio centinela
S. Martínez García
Servicio de Dermatología, Hospital Regional Universitario Carlos Haya, Málaga, España
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Pérez García, A. Mateu Puchades, O. Sanmartín Jiménez" "autores" => array:3 [ 0 => array:2 [ "nombre" => "M.P." "apellidos" => "Pérez García" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Mateu Puchades" ] 2 => array:2 [ "nombre" => "O." 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Ródenas" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J.M." "apellidos" => "Ródenas" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0001731019301103" "doi" => "10.1016/j.ad.2019.03.001" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731019301103?idApp=UINPBA000044" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301738?idApp=UINPBA000044" "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301738/v1_201907040838/en/main.assets" ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Commentaries</span>" "titulo" => "Sentinel Lymph Node Biopsy" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "425" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "S. Martínez García" "autores" => array:1 [ 0 => array:3 [ "nombre" => "S." "apellidos" => "Martínez García" "email" => array:1 [ 0 => "silvestremg@eresmas.net" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Hospital Regional Universitario Carlos Haya, Málaga, España" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Biopsia selectiva del ganglio centinela" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Sentinel lymph node (SLN) biopsy is currently considered the gold standard for nodal staging in cutaneous melanoma.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The technique, however, has been surrounded by controversy since it was first described by Morton et al.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">1</span></a> in 1992. In the initial years, when it was theorized that melanoma spread according to a stepwise pattern, SLN biopsy was used to reduce the performance of unnecessary lymph node dissections.</p><p id="par0015" class="elsevierStylePara elsevierViewall">SLN biopsy provides information on lymphatic drainage basins, enabling more accurate patient follow-up. It can also be used to identify subclinical disease in patients who could benefit from early adjuvant treatments that are showing very promising results.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The discovery, however, that SLN biopsy does not improve overall survival and can only offer prognostic information, combined with the emergence of new models explaining melanoma spread (e.g., the simultaneous and differential spread models),<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">2</span></a> called for increasing caution regarding its use.</p><p id="par0025" class="elsevierStylePara elsevierViewall">This article presents a retrospective review of complications and sequelae in 124 patients with primary melanoma who underwent SLN biopsy. The authors found a high rate of complications (37.9%) compared with previous studies, but this could be because they also considered complications in patients who underwent subsequent lymph node dissection.The authors argue that clinicians must not only carefully analyze the already controversial use of SLN biopsy, but also weigh up potential benefits and risks.</p><p id="par0030" class="elsevierStylePara elsevierViewall">Risk of surgical complications must always be assessed on a case-by-case basis before indicating SLN biopsy.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martínez García S. Biopsia selectiva del ganglio centinela. Actas Dermosifiliogr. 2019;110:425.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:2 [ 0 => array:3 [ "identificador" => "bib0015" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Technical details of intraoperative lymphatic mapping for early stage melanoma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.L. Morton" 1 => "D.R. Wen" 2 => "J.H. Wong" 3 => "J.S. Economou" 4 => "L.A. Cagle" 5 => "F.K. Storm" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Surg" "fecha" => "1992" "volumen" => "127" "paginaInicial" => "392" "paginaFinal" => "399" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1558490" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0020" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Linfadenectomía tras una biopsia positiva del ganglio centinela en el melanoma: un cambio de paradigma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Á. Pizarro" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2018" "volumen" => "109" "paginaInicial" => "293" "paginaFinal" => "384" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000011000000006/v1_201907040838/S1578219019301647/v1_201907040838/en/main.assets" "Apartado" => array:4 [ "identificador" => "66476" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Commentaries" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000011000000006/v1_201907040838/S1578219019301647/v1_201907040838/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219019301647?idApp=UINPBA000044" ]
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