Cutaneous Pseudolymphomas | Actas Dermo-Sifiliográficas

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Blanes Martínez, B. Encabo-Durán" "autores" => array:3 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Romero-Pérez" ] 1 => array:4 [ "nombre" => "M." "apellidos" => "Blanes Martínez" "email" => array:1 [ 0 => "blanes_marmar@gva.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 2 => array:2 [ "nombre" => "B." 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Note the merging germinal centers devoid of the mantel zone, simulating a B-cell lymphoma (hematoxylin-eosin, original magnification ×20)." ] ] ] "textoCompleto" => "IntroductionCutaneous pseudolymphomas are benign reactive lymphoid proliferations that simulate cutaneous lymphomas clinically, histologically, or both clinically and histologically.<a class="elsevierStyleCrossRefs" href="#bib0725">1–6</a> The concept was described for the first time in 1891 by Kaposi under the name sarcomatosis cutis. Since then, these proliferations have received many names and the initial descriptions all corresponded to B-cell pseudolymphoma.<a class="elsevierStyleCrossRefs" href="#bib0740">4,5,7,8</a>Traditionally, cutaneous pseudolymphomas have been classified according to their histologic and immunophenotypic characteristics or rather in relation to the lymphoma they simulate. In other words, they are categorized as cutaneous B-cell pseudolymphomas or cutaneous T-cell pseudolymphomas, depending on the predominant lymphocytic component.<a class="elsevierStyleCrossRef" href="#bib0765">9</a> While the distinction is frequently artificial, this classification system is still the widely used system for categorizing pseudolymphomas.The list of cutaneous pseudolymphomas has grown in recent years with the inclusion of multiple reactive conditions with histopathologic features mimicking those of true lymphomas. It is also noteworthy that several entities that were originally considered to be cutaneous pseudolymphomas have since been reclassified as low-grade lymphomas based on clinical and pathologic findings, molecular biology studies, and follow-up data.<a class="elsevierStyleCrossRef" href="#bib0750">6</a>Epidemiological data on cutaneous pseudolymphomas are scarce, although B-cell pseudolymphomas appear to be more common than their T-cell counterparts, and they are also more common in female patients.<a class="elsevierStyleCrossRefs" href="#bib0740">4,5,10</a> Cutaneous pseudolymphoma generally affects adults, although it can occur at any age. No familial cases have been reported.<a class="elsevierStyleCrossRef" href="#bib0735">3</a>The proliferation of skin-associated lymphoid tissue (SALT), the cutaneous analog of mucosa-associated lymphoid tissue (MALT), following antigenic stimulation has been proposed as a contributory factor in the pathogenesis of cutaneous pseudolymphoma .<a class="elsevierStyleCrossRef" href="#bib0775">11</a> Accordingly, cutaneous pseudolymphoma could potentially progress to a true cutaneous lymphoma with permanent antigenic stimulation, as occurs in the gastric mucosa in the presence of persistent Helicobacter pylori infection.<a class="elsevierStyleCrossRef" href="#bib0780">12</a> However, while there have been some reports of progression to cutaneous lymphoma,<a class="elsevierStyleCrossRefs" href="#bib0785">13–17</a> true progression from a correctly diagnosed pseudolymphoma is very rare, if not impossible.To diagnose cutaneous pseudolymphoma it is necessary to contrast clinical and histologic findings, with assessment of the architecture and composition of the inflammatory infiltrate, and to complement these findings with immunohistochemistry and gene rearrangement studies.<a class="elsevierStyleCrossRefs" href="#bib0750">6,18,19</a> These clonality studies generally reveal a polyclonal pattern. Nevertheless, it is not always possible to demonstrate clonality in true lymphomas, and certain pseudolymphomas have monoclonal B-cell and T-cell populations.<a class="elsevierStyleCrossRefs" href="#bib0745">5,8,20–26</a> Accordingly, although gene arrangement studies are useful, their results must be interpreted with caution and within the context of the data available.In the rest of this paper we will describe the main types of cutaneous pseudolymphoma (<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>).<elsevierMultimedia ident="tbl0005"></elsevierMultimedia>Lupus Erythematosus PanniculitisLupus with subcutaneous involvement, a condition known as lupus erythematosus panniculitis, can raise clinical and particularly histologic suspicions of panniculitis-like T-cell lymphoma.<a class="elsevierStyleCrossRefs" href="#bib0750">6,27</a>Lupus erythematosus panniculitis presents as plaques or subcutaneous nodules in areas rarely affected by other forms of panniculitis, such as the face, the shoulders, and the proximal aspect of the arms. Antinuclear antibodies and other diagnostic criteria for systemic lupus erythematosus may be absent.Histologic examination shows a predominantly lobular panniculitis with dense lymphoid infiltrates in the deep dermis and the hypodermis, along with wide fibrous septae on occasions. The infiltrate is mixed, with abundant B cells, plasma cells, and clusters of plasmacytoid dendritic cells, frequently forming reactive germinal centers. The dermal-epidermal junction may show the characteristic interface dermatitis associated with the underlying connective tissue disease, and this is a key finding for the differential diagnosis. In lupus erythematosus panniculitis, unlike in panniculitis-like T-cell lymphoma, histology does not show cytophagocytosis or adipocyte rimming (atypical lymphoid cells surrounding the adipocytes). T-cell receptor (TCR) gene rearrangement will show a polyclonal pattern.<a class="elsevierStyleCrossRefs" href="#bib0750">6,27</a>Histologic features of panniculitis-like T-cell lymphoma and lupus erythematosus panniculitis may, albeit rarely, overlap. In one study of 83 patients with panniculitis-like T-cell lymphoma, Willemze et al.<a class="elsevierStyleCrossRef" href="#bib0860">28</a> observed abundant plasma cells interspersed with CD4+ T cells in 4 patients who also had lupus erythematosus, leading to an initial misdiagnosis of lupus erythematous panniculitis. The presence of cellular atypia together with a loss of pan-T-cell markers and/or clonal TCR-γ rearrangement was key to establishing a correct diagnosis.<a class="elsevierStyleCrossRef" href="#bib0860">28</a>Pseudolymphoma in TattoosAlthough uncommon, pseudolymphomatous reactions to tattoo ink can occur, and a variable latency period has been described.<a class="elsevierStyleCrossRefs" href="#bib0865">29,30</a> Red ink is the most common ink involved in these reactions.<a class="elsevierStyleCrossRef" href="#bib0870">30</a> Tattoo ink–related pseudolymphoma presents as subcutaneous nodules.<a class="elsevierStyleCrossRef" href="#bib0775">11</a>Histologic examination shows a dense diffuse dermal infiltrate with perivascular and periadnexal accentuation composed mainly of small lymphocytes (most often T cells but there may also be B cells or a mixture) and macrophages. Additional findings include eosinophils, plasma cells, histiocytes, and giant multinucleated cells. These cells may form lymphoid follicles with germinal centers or patterns similar to those seen in mycosis fungoides. Spongiosis, exocytosis, and basal vacuolar degeneration may also be observed in the epidermis.<a class="elsevierStyleCrossRefs" href="#bib0865">29,30</a> The presence of macrophages phagocytizing the pigment is a key diagnostic clue.Pseudolymphoma at the Site of VaccinationAn intense inflammatory response simulating cutaneous lymphoma can also occur at vaccination sites as the result of a delayed hypersensitivity reaction to vaccine components. This reaction is particularly seen in vaccines containing aluminum, as this metal contributes to the delayed absorption of other components, thereby prolonging the antigen stimulus.<a class="elsevierStyleCrossRefs" href="#bib0750">6,31</a> It presents as papules or superficial or deep erythematous nodules.<a class="elsevierStyleCrossRefs" href="#bib0750">6,32</a>The histologic pattern may be lichenoid, simulating mycosis fungoides, or nodular, simulating follicle center lymphoma (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). In this second case, however, bcl-6+ cells will not be observed outside the reactive germinal centers.<a class="elsevierStyleCrossRefs" href="#bib0750">6,33</a> Clusters of CD30+ cells may occasionally be observed.<a class="elsevierStyleCrossRef" href="#bib0885">33</a> When aluminum is involved, the histiocytes in the infiltrate, which may be solitary or arranged in clusters forming epithelioid granulomas, typically have abundant granular and basophilic cytoplasm (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) corresponding to intracellular aluminum deposits.<elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia>Lymphocytoma CutisLymphocytoma cutis was first described by Spiegler in 1894. It is the prototype of cutaneous B-cell pseudolymphoma and perhaps the most common variant. It represents an exaggerated local immune response to diverse stimuli, the most widely described of which are arthropod bites.<a class="elsevierStyleCrossRefs" href="#bib0750">6,32–37</a> One of the most classic associations is with the spirochete Borrelia burgdorferi following a bite from a Ixodes tick.<a class="elsevierStyleCrossRefs" href="#bib0830">22,38</a>Lymphocytoma cutis typically presents as a solitary reddish nodule (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>) or less frequently as plaques or crops of papules. The face and neck are the most common sites of involvement. Lesions on the earlobe, nipples, or scrotum are highly characteristic of B burgdorferi–associated lymphocytoma cutis.<a class="elsevierStyleCrossRefs" href="#bib0750">6,38–40</a><elsevierMultimedia ident="fig0015"></elsevierMultimedia>Miliarial-type lesions have also been described, but less frequently. These present as multiple, symmetric, monomorphous translucent micropapules on the head and neck and they can be asymptomatic or slightly pruritic.<a class="elsevierStyleCrossRefs" href="#bib0775">11,41,42</a>Histology reveals a dense nodular lymphoid infiltrate in the dermis, with germinal centers that characteristically lack a mantle zone and may merge. Although the infiltrate in pseudolymphomas tends to be top heavy (i.e., more pronounced in the superficial dermis) rather than bottom heavy like in lymphomas, in B burgdorferi–associated lymphocytoma cutis, infiltrates are often found throughout the dermis and even in the superficial layers of the subcutaneous tissue.<a class="elsevierStyleCrossRef" href="#bib0750">6</a>The infiltrate is formed by plasma cells, eosinophils, abundant reactive T cells, and tingible body macrophages (<a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>). This heterogeneity is another factor to take into account when distinguishing cutaneous pseudolymphomas from true lymphomas, as these tend to have a more uniform infiltrate. The predominant immunophenotype is a germinal center B-cell type, with positive staining for CD20, CD10, and bcl-6, and negative staining for bcl-2. The germinal centers tend to have a very high proliferative index, but unlike in true cutaneous lymphomas, cellular atypia and preservation of adnexal structures are not observed. Rearrangement analysis usually, but not always, shows a polyclonal pattern. Assessment of clonality in more than 1 lesion is very useful for differentiating pseudolymphomas and lymphomas in patients with several lesions. Detection of the same clone in 2 lesions or in the same lesion at different stages of development would point to a diagnosis of lymphoma.<a class="elsevierStyleCrossRefs" href="#bib0750">6,39,43</a><elsevierMultimedia ident="fig0020"></elsevierMultimedia>Pseudolymphoma in Acrodermatitis Chronica Atrophicans LesionsPseudolymphoma has been described in the lesions of patients with acrodermatitis chronica atrophicans, which is a delayed cutaneous manifestation of B burgdorferi infection. Histologically, lesions can display 2 patterns: one simulating mycosis fungoides and the other (less frequent) one simulating cutaneous B-cell lymphoma. The rearrangement study shows a polyclonal infiltrate.<a class="elsevierStyleCrossRefs" href="#bib0940">44,45</a>Pseudolymphomatous FolliculitisPseudolymphomatous folliculitis is a cutaneous pseudolymphoma characterized by the presence of hyperplastic hair follicles together with a lymphoid infiltrate that can mimic cutaneous lymphoma. It presents with a single or, less frequently, several dome-shaped or nodular lesions on the face, scalp, or trunk.<a class="elsevierStyleCrossRefs" href="#bib0780">12,46</a>Histologically, pseudolymphomatous folliculitis can simulate small-to-medium-sized pleomorphic T-cell lymphoma, follicle center B-cell lymphoma, or even folliculotropic mycosis fungoides. A dense lymphocytic infiltrate is located predominantly around the hair follicles, which show hyperplastic changes and thickened walls. Clusters of perifollicular S100+ and CD1A+ histiocytes may occasionally be seen. Rearrangement studies show a polyclonal infiltrate.<a class="elsevierStyleCrossRefs" href="#bib0775">11,12,46–50</a>Lymphomatoid Drug ReactionNumerous drugs can induce cutaneous lymphoid infiltrates that resemble lymphoma clinically, histologically, or both clinically and histologically. The most frequently implicated drugs are anticonvulsants and antihypertensives, but others have been described (<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>).<elsevierMultimedia ident="tbl0010"></elsevierMultimedia>Clinically, lymphomatoid drug reactions present as generalized papules, plaques, or nodules, or even erythroderma, sometimes with accentuation in sun-exposed areas.<a class="elsevierStyleCrossRefs" href="#bib0750">6,36,61</a> Lesions typically appear 2 to 8 weeks after the introduction of the offending drug, but later onset has been reported.<a class="elsevierStyleCrossRefs" href="#bib0900">36,42,62</a> The skin lesions may be accompanied by enlarged lymph nodes, fever, and less frequently hepatosplenomegaly, joint pain, and diverse blood test alterations including elevated liver enzymes and eosinophilia, particularly in cases due to anticonvulsants.<a class="elsevierStyleCrossRefs" href="#bib1025">61,63</a> Circulating Sézary cells may occasionally be detected.<a class="elsevierStyleCrossRef" href="#bib0900">36</a>Histologic findings in lymphomatoid drug reaction include a band-like T cell–predominant infiltrate with epidermal spongiosis and exocytosis, simulating mycosis fungoides. On other occasions, there may be a nodular or diffuse B-cell pattern with formation of germinal centers, simulating follicle center or marginal zone B-cell lymphoma. Cellular atypia has been described in some cases, as have abundant CD30+ cells, which can complicate diagnosis. Findings suggestive of lymphomatoid drug reaction include necrotic keratinocytes, red blood cell extravasation, pigmentary incontinence, dermal edema, absence of fibrosis in the papillary dermis, presence of other inflammatory cells in the infiltrate, and finally, negative clonality in the gene rearrangement study. Lesions in sun-exposed areas can also point to a diagnosis of lymphomatoid drug reaction.<a class="elsevierStyleCrossRefs" href="#bib0930">42,43,61,64–68</a>The condition resolves after a variable period of time on withdrawal of the drug and returns when it is reintroduced.<a class="elsevierStyleCrossRefs" href="#bib0930">42,43</a> There have been very rare reports of progression to true cutaneous lymphoma,<a class="elsevierStyleCrossRef" href="#bib1065">69</a> and in these cases the skin lesions would not disappear after withdrawal of the drug.MorpheaCollagen involvement is often not very evident in the inflammatory phase of connective tissue disorders, especially in localized scleroderma, and histology may reveal dense lymphoid infiltrates simulating cutaneous lymphoma and marginal zone B-cell lymphoma in particular. Plasma cells are almost always present and light chain gene rearrangement studies will show a polyclonal infiltrate.<a class="elsevierStyleCrossRefs" href="#bib0750">6,70,71</a> It is essential to contrast clinical and pathologic findings in such cases.Acral Pseudolymphomatous Angiokeratoma/Small Papular PseudolymphomaAcral pseudolymphomatous angiokeratoma, which was originally described under the acronym APACHE (acral pseudolymphoma angiokeratoma in children), is a rare benign condition of unknown etiology and pathogenesis, although some authors believe it is a hypersensitivity reaction to insect bites.<a class="elsevierStyleCrossRefs" href="#bib0740">4,6,72,73</a> It is characterized by papules or clusters of asymptomatic red-purple nodules, typically located at acral sites, and is more common in children and adolescents.<a class="elsevierStyleCrossRefs" href="#bib0775">11,36,72–75</a>Histologic findings include a dense well-differentiated nodular B-cell and T-cell infiltrate that generally spares the adnexal structures, in addition to plasma cells, eosinophils, and on occasions histiocytes and giant multinucleated cells. A proliferation of capillary vessels may be observed. The epidermis is normally spared, although there have been reports of basal vacuolization, exocytosis, and spongiosis.<a class="elsevierStyleCrossRefs" href="#bib0750">6,72</a>T Cell–Rich Angiomatoid Polypoid PseudolymphomaT cell–rich angiomatoid polypoid pseudolymphoma has similar histologic findings to acral pseudolymphomatous angiokeratoma, but it is characterized by solitary polypoid lesions at nonacral sites, with a predilection for the head and trunk. It typically affects young adults.<a class="elsevierStyleCrossRefs" href="#bib0775">11,76,77</a> Another difference between the 2 entities is that in angiomatoid polypoid pseudolymphoma, there is a predominance of CD4+ T cells in the infiltrate and the prominent thick-walled vessels seen in acral pseudolymphomatous angiokeratoma are absent. Both entities must be distinguished from angioplasmacellular hyperplasia, in which the infiltrate is much richer in plasma cells.<a class="elsevierStyleCrossRefs" href="#bib1100">76–78</a>Pretibial Lymphoplasmacytic Plaque in ChildrenPretibial lymphoplasmacytic plaque is a benign chronic condition of unknown etiology that is probably reactive in nature. It presents as red-purple asymptomatic papules or well-delimited plaques that preferentially affect the anterior surface of the tibia in children. Histologically, it is similar to acral pseudolymphomatous angiokeratoma, although there is a much more pronounced presence of plasma cells, together with lymphocytes and prominent vessels. Vacuolization, exocytosis, and apoptotic bodies may be observed in the epidermis. The gene rearrangement study shows a polyclonal pattern.<a class="elsevierStyleCrossRefs" href="#bib1115">79–82</a>Secondary SyphilisHistology of secondary syphilis lesions and less frequently of primary or tertiary syphilis lesions may occasionally reveal a lymphoplasmacytic infiltrate simulating marginal zone B-cell cutaneous lymphoma. The coexistence of interface/lichenoid dermatitis or granulomatous inflammation is an important diagnostic clue. Rearrangement studies show a polyclonal pattern and specific immunohistochemical staining for Treponema pallidum confirms the presence of these organisms. Lesions resolve quickly with antibiotic treatment. It is also worth noting that certain cases of malignant syphilis may also feature lesions that are clinically indistinguishable from lymphomatoid papulosis. The entities are also difficult to differentiate histologically, unless abundant plasma cells and spirochetes are observed.<a class="elsevierStyleCrossRefs" href="#bib0750">6,83,84</a>Persistent Arthropod Bite ReactionNodular scabies is the paradigm of persistent arthropod bite reaction, although this can be caused by arthropods other than the scabies mite. A delayed hypersensitivity reaction to a component of the mite has been implicated in the pathogenesis of the reaction, although it is rarely identified in lesions. Clinically, arthropod bite reaction presents as reddish papules or persistent pruritic nodules, despite adequate treatment.<a class="elsevierStyleCrossRefs" href="#bib0750">6,36</a>Histologically, nodular scabies may simulate mycosis fungoides, lymphomatoid papulosis, Hodgkin lymphoma, and in some cases, cutaneous B-cell lymphoma. The most frequent finding is a dense perivascular superficial and deep lymphoid infiltrate with predominant T cells, which are frequently CD30+, together with plasma cells, eosinophils, and prominent vessels.<a class="elsevierStyleCrossRefs" href="#bib0750">6,12,36,85,86</a>Actinic ReticuloidActinic reticuloid is a chronic photodermatitis that tends to affect elderly patients, and men in particular. It is characterized by extreme photosensitivity across a wide spectrum of UV radiation.<a class="elsevierStyleCrossRefs" href="#bib0750">6,36,43,87</a> Its pathogenesis remains unclear, although it has been proposed that a normal component of skin might become antigenic following alterations induced by a photoallergic reaction.<a class="elsevierStyleCrossRefs" href="#bib1160">88,89</a>In its early phases, actinic reticuloid presents as a highly pruritic eczematous dermatitis; there is a tendency towards localized lichenification in sun-exposed areas that may then spread to other areas.<a class="elsevierStyleCrossRefs" href="#bib0900">36,88</a> Histology reveals a mixed perivascular superficial or deep infiltrate that may include some atypical mononuclear cells. Actinic reticuloid can form a band-like pattern with lymphocytic exocytosis, simulating mycosis fungoides, or a more diffuse pattern, simulating peripheral T-cell lymphoma. The CD4/CD8 ratio, however, is lower in the case of actinic reticuloid.<a class="elsevierStyleCrossRefs" href="#bib0900">36,43,88</a>As the condition progresses, patients may develop erythroderma, enlarged lymph nodes, ectropion and up to 10% of Sézary cells in peripheral blood, complicating the differential diagnosis.<a class="elsevierStyleCrossRefs" href="#bib0750">6,36,90–92</a> Unlike mycosis fungoides and Sézary syndrome, sensitivity to UV-B, UV-A, and even visible light is very high and can exacerbate the condition.<a class="elsevierStyleCrossRef" href="#bib1160">88</a>Actinic reticuloid is a chronic condition that does not tend to resolve spontaneously.<a class="elsevierStyleCrossRefs" href="#bib0935">43,93</a> Sun-protection measures are essential, as is avoidance of implicated allergens.<a class="elsevierStyleCrossRef" href="#bib0750">6</a>Lichen SclerosusGenital lichen sclerosus, particularly in its early phases, has histologic features that require consideration of mycosis fungoides in the differential diagnosis. Lesions show a dense band-like lymphoid infiltrate in the superficial dermis and marked epidermotropism.<a class="elsevierStyleCrossRefs" href="#bib0750">6,94</a> To confuse matters even further, gene rearrangement studies reveal a clonal pattern in a considerable number of cases.<a class="elsevierStyleCrossRefs" href="#bib1195">95,96</a> Cellular atypia is not generally seen in the infiltrate in lichen sclerosus, and intraepidermal lymphocytes tend to be located in the lower part of the epidermis, without pagetoid spread; interface changes are also common.<a class="elsevierStyleCrossRef" href="#bib1190">94</a> It is essential to contrast clinical and pathologic findings.Lichen AureusLichen aureus also has histologic features that can be confused with mycosis fungoides, and in some cases, there may be molecular evidence of clonality.<a class="elsevierStyleCrossRef" href="#bib0750">6</a> Again, it is important to carefully correlate clinical and pathologic findings.Solitary T-Cell PseudolymphomaSolitary T-cell pseudolymphoma is one of the most controversial variants of pseudolymphoma. With histologic features similar to those of mycosis fungoides and occasional monoclonality, this entity can present as superficial lesions on the breasts of adult women that resemble lichenoid keratosis lesions. In other cases, it appears as solitary nodular lesions with histologic findings similar to those of small- to-medium-sized pleomorphic T-cell lymphoma. It follows an indolent course and excision is curative.<a class="elsevierStyleCrossRefs" href="#bib0750">6,97,98</a>Lichenoid KeratosisLichenoid keratosis is a benign epithelial tumor related to seborrheic keratosis and lentigines that affects elderly patients. It appears as small scaling plaques normally located on the trunk. Histologically, the findings can simulate those of mycosis fungoides, with a dense band-like lymphocytic infiltrate with a certain degree of epidermotropism and occasional monoclonality. Clinical-pathologic correlation is essential.<a class="elsevierStyleCrossRefs" href="#bib0750">6,99–101</a>Lymphomatoid Contact DermatitisDescribed for the first time by Orbaneja et al.<a class="elsevierStyleCrossRef" href="#bib1230">102</a> in 1976, lymphomatoid contact dermatitis has similar clinical and histopathologic features to mycosis fungoides. It presents as pruritic erythematous plaques, with an oscillating course, and is more common in middle-aged men.<a class="elsevierStyleCrossRefs" href="#bib1230">102–104</a> Histology shows a band-like T cell–predominant infiltrate component and epidermotropism (<a class="elsevierStyleCrossRef" href="#fig0025">Fig. 5</a>). However, in the epidermis there may be spongiosis or microvesiculation; cellular atypia is very low and there is no evidence of Pautrier microabscesses, although it is not uncommon to see small collections of keratinocytes intermixed with Langerhans cells and some lymphocytes that are frequently confused with keratinocytes (<a class="elsevierStyleCrossRef" href="#fig0030">Fig. 6</a>). TCR rearrangement studies generally show a polyclonal infiltrate.<a class="elsevierStyleCrossRefs" href="#bib0935">43,94,103,104</a><elsevierMultimedia ident="fig0025"></elsevierMultimedia><elsevierMultimedia ident="fig0030"></elsevierMultimedia><a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a> shows the allergens that have been implicated in lymphomatoid contact dermatitis.<a class="elsevierStyleCrossRefs" href="#bib1230">102,105–115</a> Patch tests show sensitization<a class="elsevierStyleCrossRef" href="#bib1235">103</a> and the condition resolves with avoidance of exposure to causative allergens.<a class="elsevierStyleCrossRef" href="#bib0750">6</a><elsevierMultimedia ident="tbl0015"></elsevierMultimedia>Atypical CD8+ Lymphoid Proliferation in Patients With Human Immunodeficiency VirusAtypical CD8+ lymphoid proliferation is a polyclonal lymphoproliferative disorder with an apparently reactive nature that is clinically and histologically similar to T-cell lymphoma and affects individuals with human immunodeficiency virus infection, particularly when they are severely immunocompromised. Its pathogenesis is unknown.<a class="elsevierStyleCrossRef" href="#bib1300">116</a>Clinically, it presents as a generalized pruritic rash frequently associated with pigment changes (hypopigmentation or hyperpigmentation) and lichenification. Lymphadenopathy, splenomegaly, eosinophilia, and, on occasions, circulating Sézary cells have also been described.<a class="elsevierStyleCrossRefs" href="#bib1300">116–118</a>The histologic features resemble those of mycosis fungoides, but there is a predominance of CD8+ lymphocytes. Clonality studies are negative.<a class="elsevierStyleCrossRefs" href="#bib1300">116,119–121</a>CD30+ T-Cell PseudolymphomaThe presence of large atypical CD30+ T cells has been described in numerous reactive skin disorders in recent years (<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>). In these pseudolymphomas, CD30+ cells do not form clusters but are rather distributed throughout the infiltrate. Rearrangement studies show a polyclonal pattern. Histology frequently shows evidence of the underlying condition.<a class="elsevierStyleCrossRefs" href="#bib0750">6,122</a><elsevierMultimedia ident="tbl0020"></elsevierMultimedia>Immunoglobulin G4–Related Sclerosing DiseaseImmunoglobulin (Ig) G4-related sclerosing disease is characterized by a lymphoplasmacytic infiltrate featuring IgG4+ plasma cells, together with sclerotic changes and elevated IgG4 serum levels (>135mg/dL).<a class="elsevierStyleCrossRef" href="#bib1360">128</a>Skin involvement is rare, but it can occur in isolation and without elevated serum IgG4 titers. IgG4-related sclerosing disease presents as plaques or as solitary or multiple nodules on the head and/or extremities of middle-aged, predominantly male, adults.<a class="elsevierStyleCrossRefs" href="#bib1365">129–132</a>Histology shows a mixed inflammatory infiltrate immersed in a sclerotic stroma in the dermis, and occasionally in the subcutaneous tissue.<a class="elsevierStyleCrossRefs" href="#bib0775">11,128,130</a> An IgG4 to total IgG ratio of above 40% is highly suggestive of IgG4-related sclerosing disease.<a class="elsevierStyleCrossRef" href="#bib1360">128</a>Annular Lichenoid DermatitisAnnular lichenoid dermatitis is an entity of unknown pathogenesis, initially described in children, that shares many histologic and immunophenotypic characteristics with mycosis fungoides. It presents as solitary or multiple asymptomatic reddish-brown annular plaques with raised borders on the trunk.Histologic examination shows a band-like CD8+-predominant lymphocytic infiltrate, vacuolar degeneration at the dermal-epidermal junction, and necrotic keratinocytes at the tips of the rete ridges. Marked epidermotropism, Pautrier microabscesses, and fibrosis in the papillary dermis are not observed. Monoclonality is shown to be absent by rearrangement studies.<a class="elsevierStyleCrossRefs" href="#bib1385">133–135</a>Palpable Migratory Arciform ErythemaPalpable migratory arciform erythema is an uncommon entity that presents with erythematous annular plaques located predominantly on the trunk with a centrifugal distribution; the lesions tend to disappear within days or weeks. Histologically there is a perivascular and periadnexal CD4+-predominant lymphocytic infiltrate, without epidermal involvement, plasma cells, or interstitial mucin. A polyclonal pattern is detected by gene rearrangement studies in most cases.<a class="elsevierStyleCrossRefs" href="#bib1400">136,137</a>Other Cutaneous PseudolymphomasOther cutaneous pseudolymphomas can also simulate cutaneous lymphomas clinically and/or histologically.In the inflammatory phase of vitiligo, which is characterized by erythematous, scaling plaques rather than achromic patches, histology can reveal a dense band-like lichenoid infiltrate with lymphocytic exocytosis simulating mycosis fungoides in the lower part of the epidermis. Most of the cells are CD8+. Follow-up is essential.<a class="elsevierStyleCrossRef" href="#bib1410">138</a>There have also been reports of pseudolymphomas in relation to herpes simplex and herpes zoster infections that can mimic T-cell or B-cell lymphomas or CD30+ lymphoproliferative diseases.<a class="elsevierStyleCrossRef" href="#bib1415">139</a>Atypical cells have also been described in cases of chronic discoid lupus erythematosus.<a class="elsevierStyleCrossRef" href="#bib0750">6</a> Jessner lymphocytic infiltrate of the skin can also be histologically confused with B-cell lymphoma. Polyclonal infiltrates and CD123+ plasmacytoid monocytes can help to distinguish between these disorders.<a class="elsevierStyleCrossRefs" href="#bib0935">43,140</a>The true nature of pityriasis lichenoides et varioliformis acuta (PLEVA) is still a matter of debate. PLEVA is a generally benign condition and is probably a reactive disorder with an infectious or inflammatory origin.<a class="elsevierStyleCrossRefs" href="#bib1425">141–143</a> However, there have been reports of monoclonal rearrangement<a class="elsevierStyleCrossRef" href="#bib1425">141</a> and, at least in the febrile ulceronecrotic form, an association with cytotoxic cutaneous lymphoma has been considered. The 2 entities have overlapping clinical and histologic findings, although infiltrates are not as dense or as deep in PLEVA, and cellular atypia is also less pronounced.<a class="elsevierStyleCrossRef" href="#bib1440">144</a> Follow-up is particularly important in PLEVA.Conflicts of InterestThe authors declare that they have no conflicts of interest." "textoCompletoSecciones" => array:1 [ "secciones" => array:33 [ 0 => array:3 [ "identificador" => "xres826626" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec822937" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres826625" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec822936" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Lupus Erythematosus Panniculitis" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Pseudolymphoma in Tattoos" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Pseudolymphoma at the Site of Vaccination" ] 8 => array:2 [ "identificador" => "sec0025" "titulo" => "Lymphocytoma Cutis" ] 9 => array:2 [ "identificador" => "sec0030" "titulo" => "Pseudolymphoma in Acrodermatitis Chronica Atrophicans Lesions" ] 10 => array:2 [ "identificador" => "sec0035" "titulo" => "Pseudolymphomatous Folliculitis" ] 11 => array:2 [ "identificador" => "sec0040" "titulo" => "Lymphomatoid Drug Reaction" ] 12 => array:2 [ "identificador" => "sec0045" "titulo" => "Morphea" ] 13 => array:2 [ "identificador" => "sec0050" "titulo" => "Acral Pseudolymphomatous Angiokeratoma/Small Papular Pseudolymphoma" ] 14 => array:2 [ "identificador" => "sec0055" "titulo" => "T Cell–Rich Angiomatoid Polypoid Pseudolymphoma" ] 15 => array:2 [ "identificador" => "sec0060" "titulo" => "Pretibial Lymphoplasmacytic Plaque in Children" ] 16 => array:2 [ "identificador" => "sec0065" "titulo" => "Secondary Syphilis" ] 17 => array:2 [ "identificador" => "sec0070" "titulo" => "Persistent Arthropod Bite Reaction" ] 18 => array:2 [ "identificador" => "sec0075" "titulo" => "Actinic Reticuloid" ] 19 => array:2 [ "identificador" => "sec0080" "titulo" => "Lichen Sclerosus" ] 20 => array:2 [ "identificador" => "sec0085" "titulo" => "Lichen Aureus" ] 21 => array:2 [ "identificador" => "sec0090" "titulo" => "Solitary T-Cell Pseudolymphoma" ] 22 => array:2 [ "identificador" => "sec0095" "titulo" => "Lichenoid Keratosis" ] 23 => array:2 [ "identificador" => "sec0100" "titulo" => "Lymphomatoid Contact Dermatitis" ] 24 => array:2 [ "identificador" => "sec0105" "titulo" => "Atypical CD8 Lymphoid Proliferation in Patients With Human Immunodeficiency Virus" ] 25 => array:2 [ "identificador" => "sec0110" "titulo" => "CD30 T-Cell Pseudolymphoma" ] 26 => array:2 [ "identificador" => "sec0115" "titulo" => "Immunoglobulin G4–Related Sclerosing Disease" ] 27 => array:2 [ "identificador" => "sec0120" "titulo" => "Annular Lichenoid Dermatitis" ] 28 => array:2 [ "identificador" => "sec0125" "titulo" => "Palpable Migratory Arciform Erythema" ] 29 => array:2 [ "identificador" => "sec0130" "titulo" => "Other Cutaneous Pseudolymphomas" ] 30 => array:2 [ "identificador" => "sec0135" "titulo" => "Conflicts of Interest" ] 31 => array:2 [ "identificador" => "xack277332" "titulo" => "Acknowledgments" ] 32 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-12-21" "fechaAceptado" => "2016-05-01" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec822937" "palabras" => array:3 [ 0 => "Pseudolymphoma" 1 => "Skin" 2 => "Cutaneous lymphoid hyperplasia" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec822936" "palabras" => array:3 [ 0 => "Pseudolinfoma" 1 => "Piel" 2 => "Hiperplasia linfoide cutánea" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "The term cutaneous pseudolymphoma refers to benign reactive lymphoid proliferations in the skin that simulate cutaneous lymphomas. It is a purely descriptive term that encompasses various reactive conditions with a varied etiology, pathogenesis, clinical presentation, histology, and behavior. We present a review of the different types of cutaneous pseudolymphoma. To reach a correct diagnosis, it is necessary to contrast clinical, histologic, immunophenotypic, and molecular findings. Even with these data, in some cases only the clinical course will confirm the diagnosis, making follow-up essential." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "El término pseudolinfoma cutáneo designa proliferaciones linfoides cutáneas benignas de naturaleza reactiva que simulan linfomas cutáneos. Se trata de un término puramente descriptivo que engloba diferentes entidades reactivas, con diversa etiología, patogénesis, presentación clínica, histología y comportamiento. En el presente artículo revisaremos los distintos tipos de pseudolinfoma cutáneo. Como veremos, para llegar al correcto diagnóstico de los mismos será preciso en cada caso la integración de los datos clínicos con los histopatológicos, inmunofenotípicos y moleculares. Incluso entonces, en ocasiones solo la evolución confirmará el diagnóstico, por lo que el seguimiento será esencial." ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Romero-Pérez D, Blanes Martínez M, Encabo-Durán B. Pseudolinfomas cutáneos. Actas Dermosifiliogr. 2016;107:640–651." ] ] "multimedia" => array:10 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 746 "Ancho" => 998 "Tamanyo" => 399389 ] ] "descripcion" => array:1 [ "en" => "Lymphoid follicles in the subcutaneous tissue separated by areas of fibrosis in this vaccination-induced pseudolymphoma (hematoxylin-eosin, original magnification ×10)." ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 746 "Ancho" => 998 "Tamanyo" => 381561 ] ] "descripcion" => array:1 [ "en" => "Histiocytes with basophilic granular cytoplasm corresponding to the aluminum component of a vaccine, intermixed with lymphocytes, together with eosinophils and plasma cells (hematoxylin-eosin, original magnification ×40)." ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figure 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 602 "Ancho" => 903 "Tamanyo" => 130098 ] ] "descripcion" => array:1 [ "en" => "Lymphocytoma cutis. Solitary lesion on the back." ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Figure 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 746 "Ancho" => 998 "Tamanyo" => 417904 ] ] "descripcion" => array:1 [ "en" => "Histologic image of the lymphocytoma cutis shown in <a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>. Dense mixed dermal infiltrate. Note the merging germinal centers devoid of the mantel zone, simulating a B-cell lymphoma (hematoxylin-eosin, original magnification ×20)." ] ] 4 => array:7 [ "identificador" => "fig0025" "etiqueta" => "Figure 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 711 "Ancho" => 998 "Tamanyo" => 242856 ] ] "descripcion" => array:1 [ "en" => "Lymphomatoid contact dermatitis. In this patient sensitized to methylchloroisothiazolinone and colophony, histology showed a band-like lymphocytic infiltrate and in some areas without spongiosis, clusters in the epidermis reminiscent of Pautrier microabscesses." ] ] 5 => array:7 [ "identificador" => "fig0030" "etiqueta" => "Figure 6" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr6.jpeg" "Alto" => 745 "Ancho" => 993 "Tamanyo" => 232324 ] ] "descripcion" => array:1 [ "en" => "Detailed view of Pautrier pseudomicroabscesses. The lesions resolved after avoidance of the causative allergens." ] ] 6 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at1" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lupus erythematosus panniculitis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma in tattoos \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma at the site of vaccination \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphocytoma cutis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma in acrodermatitis chronica atrophicans lesions \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphomatous folliculitis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphomatoid drug reaction \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Morphea \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Acral pseudolymphomatous angiokeratoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">T cell–rich angiomatoid polypoid pseudolymphoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pretibial lymphoplasmacytic plaque \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Secondary syphilis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Persistent arthropod bite reaction \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Actinic reticuloid \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichen sclerosus et atrophicus \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichen aureus \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Solitary T-cell pseudolymphoma \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichenoid keratosis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphomatoid contact dermatitis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Atypical lymphoid proliferation in patients with human immunodeficiency virus \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">CD30+ pseudolymphomas \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Immunoglobulin G4-related disease \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Annular lichenoid dermatitis \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Palpable migratory arciform erythema \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Other cutaneous pseudolymphomas \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1390582.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Cutaneous Pseudolymphoma." ] ] 7 => array:8 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at2" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Abbreviations: ACE, angiotensin-converting enzyme; NSAIDs, nonsteroidal anti-inflammatory drugs.Source: Ploysangam et al.,<a class="elsevierStyleCrossRef" href="#bib0900">36</a> Naciri Bennani et al.,<a class="elsevierStyleCrossRef" href="#bib0975">51</a> Imafuku et al.,<a class="elsevierStyleCrossRef" href="#bib0980">52</a> Fukamachi et al.,<a class="elsevierStyleCrossRef" href="#bib0985">53</a> Guis et al.,<a class="elsevierStyleCrossRef" href="#bib0990">54</a> Stavrianeas et al.,<a class="elsevierStyleCrossRef" href="#bib0995">55</a> Welsh et al.,<a class="elsevierStyleCrossRef" href="#bib1000">56</a> Kitagawa et al.,<a class="elsevierStyleCrossRef" href="#bib1005">57</a> Macisaac et al.,<a class="elsevierStyleCrossRef" href="#bib1010">58</a> Kim et al.,<a class="elsevierStyleCrossRef" href="#bib1015">59</a> Foley et al.<a class="elsevierStyleCrossRef" href="#bib1020">60</a>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Anticonvulsants \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Phenytoin, carbamazepine, mephenytoin, trimethadione, phenobarbital, primidone, butabarbital, methsuximide, phensuximide \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antipsychotics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Chlorpromazine, thioridazine, promethazine, methylphenidate \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top">Antihypertensives</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">ACE inhibitors \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Captopril, enalapril, benazepril \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">β-Blockers \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Atenolol, labetalol \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Calcium channel blockers \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Verapamil, diltiazem, benidipine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Diuretics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Moduretic, hydrochlorothiazide \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Cytotoxic agents \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Ciclosporin, methotrexate \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Rheumatology drugs \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Gold, salicylates, phenacetin, D-penicillamine, allopurinol, NSAIDs \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antibiotics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Penicillin, dapsone, nitrofurantoin, vancomycin \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antidepressants \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Fluoxetine, doxepin, depramine, amitriptyline, lithium \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Anxiolytics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Benzodiazepines (clonazepam, lorazepam) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antihistamines \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Diphenhydramine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">H2 antihistamines \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Cimetidine, ranitidine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Antiarrhythmics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Procainamide, mexiletine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Topical agents \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Menthol, eugenol \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sex hormones \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Estrogens, progesterone \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lipid-lowering drugs \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Lovastatin \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Biologics \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Adalimumab, infliximab, etanercept \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Other \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Lornoxicam, zoledronic acid \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1390580.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Drugs Associated With Pseudolymphomatous Cutaneous Reactions." ] ] 8 => array:8 [ "identificador" => "tbl0015" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at3" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Source: Orbaneja et al.,<a class="elsevierStyleCrossRef" href="#bib1230">102</a> Marlière et al.,<a class="elsevierStyleCrossRef" href="#bib1245">105</a> Wall et al.,<a class="elsevierStyleCrossRef" href="#bib1250">106</a> Schena et al.,<a class="elsevierStyleCrossRef" href="#bib1255">107</a> Danese et al.,<a class="elsevierStyleCrossRef" href="#bib1260">108</a> Calzavara-Pinton et al.,<a class="elsevierStyleCrossRef" href="#bib1265">109</a> Fleming et al.,<a class="elsevierStyleCrossRef" href="#bib1270">110</a> Park et al.,<a class="elsevierStyleCrossRef" href="#bib1275">111</a> Komatsu et al.,<a class="elsevierStyleCrossRef" href="#bib1280">112</a> Pely et al.,<a class="elsevierStyleCrossRef" href="#bib1285">113</a> Millican et al.,<a class="elsevierStyleCrossRef" href="#bib1290">114</a> Mendese et al.<a class="elsevierStyleCrossRef" href="#bib1295">115</a>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Phosphorus \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">N-Isopropyl-N-phenyl-4-phenylenediamine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Ethylenediamine dihydrochloride \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Napthen cobalt \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Nickel sulfate \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Paraphenylenediamine \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Gold sodium thiosulfate \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Zinc \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Squaric acid dibutylester \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Methylchloroisothiazolinone/methylisothiazolinone \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1390581.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Allergens Implicated in Lymphomatoid Contact Dermatitis." ] ] 9 => array:8 [ "identificador" => "tbl0020" "etiqueta" => "Table 4" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at4" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Source: Pulitzer et al.,<a class="elsevierStyleCrossRef" href="#bib1330">122</a> Gallardo et al.,<a class="elsevierStyleCrossRef" href="#bib1335">123</a> Nathan and Belsito,<a class="elsevierStyleCrossRef" href="#bib1340">124</a> Rose et al.,<a class="elsevierStyleCrossRef" href="#bib1345">125</a> Kim et al.,<a class="elsevierStyleCrossRef" href="#bib1350">126</a> Moreno-Ramírez et al.<a class="elsevierStyleCrossRef" href="#bib1355">127</a>" "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Infectious \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Viruses Orf Molluscum contagiosum Viral warts Herpes simplex Herpes zoster Fungi Mycobacteria Leishmaniasis Secondary syphilis Infection due to Stenotrophomonas maltophilia Skin abscesses Scabies \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Drugs \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Carbamazepine Cefuroxime Chemotherapy agents Gemcitabine Leuprolide Doxepin Antihypertensives Atenolol Amlodipine Valsartan Angiotensin-converting enzyme inhibitors Isoflavones Sertraline Gabapentin \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Other \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Arthropod bites Hidradenitis Gold acupuncture Lymphocyte recovery rash Pityriasis lichenoides et varioliformis Red sea coral lesions Atopic dermatitis Sweet Syndrome Stasis ulcers Rhinophyma Broken cysts \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1390579.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Pseudolymphomatous Disorders With Possible CD30+ Cell Proliferation." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:144 [ 0 => array:3 [ "identificador" => "bib0725" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The lymphocytic infiltrates of the skin" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Hum Pathol" "fecha" => "1974" "volumen" => "5" "paginaInicial" => "25" "paginaFinal" => "43" "link" => array:1 [ …1] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0730" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Histologic pseudomalignancies of the skin" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1976" "volumen" => "112" "paginaInicial" => "1767" "paginaFinal" => "1780" "link" => array:1 [ …1] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0735" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphomas and their histopathologic imitators" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Semin Dermatol" "fecha" => "1986" "volumen" => "5" "paginaInicial" => "322" "paginaFinal" => "333" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0740" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory diseases that simulate lymphomas: Cutaneous pseudolymphomas" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ "titulo" => "Dermatology in general medicine" "paginaInicial" => "1315" "paginaFinal" => "1327" "edicion" => "4th ed" "serieFecha" => "1993" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0745" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoid hyperplasia" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Cancer" "fecha" => "1969" "volumen" => "24" "paginaInicial" => "487" "paginaFinal" => "502" "link" => array:1 [ …1] "itemHostRev" => array:3 [ …3] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0750" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphomas of the skin. In: An illustrated guide to skin lymphoma" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Libro" => array:6 [ "edicion" => "2nd ed" "fecha" => "2004" "paginaInicial" => "155" "paginaFinal" => "176" "editorial" => "Blackwell Publishing Ltd" "editorialLocalizacion" => "Oxford" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0755" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous MALT-lymphoma: From cutaneous immunocytoma and pseudolymphoma to the current (and future) conceptions" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rom J Morphol Embryol" "fecha" => "2013" "volumen" => "54" "paginaInicial" => "7" "paginaFinal" => "12" "link" => array:1 [ …1] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0760" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential diagnosis of malignant and benign cutaneous lymphoid infiltrates: A study of 57 cases in which malignant lymphoma had been diagnosed or suspected in the skin" "autores" => array:1 [ 0 => array:2 [ …2] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cancer" "fecha" => "1979" "volumen" => "44" "paginaInicial" => "699" …2 ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0765" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunohistochemical classification of cutaneous pseudolymphomas: Delineation of distinct patterns" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0770" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Two cases of bilateral earlobe cutaneous pseudolymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/bjd.13145" "Revista" => array:7 [ …7] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib0775" "etiqueta" => "11" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphomas: Inflammatory reactive proliferations" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1586/17474086.2013.845000" "Revista" => array:6 [ …6] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib0780" "etiqueta" => "12" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphoma and cutaneous lymphoma: Facts and controversies" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.clindermatol.2010.04.005" "Revista" => array:6 [ …6] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib0785" "etiqueta" => "13" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mycosis fungoides--a disease of antigen persistence" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib0790" "etiqueta" => "14" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Is mycosis fungoides an immunoma?" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib0795" "etiqueta" => "15" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Evolution of B-cell lymphoma from pseudolymphoma. A multidisciplinary approach using histology, immunohistochemistry, and southern blot analysis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib0800" "etiqueta" => "16" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2005.04.036" "Revista" => array:6 [ …6] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib0805" "etiqueta" => "17" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis caused by nickel" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib0810" "etiqueta" => "18" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic cutaneous pseudolymphoma: An enigma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/2229-5178.131143" "Revista" => array:6 [ …6] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib0815" "etiqueta" => "19" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma: A case report with an immunohistochemical study" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib0820" "etiqueta" => "20" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnostic immunohistology: Cutaneous lymphomas and pseudolymphomas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib0825" "etiqueta" => "21" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential diagnosis between cutaneous lymphoma and pseudolymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib0830" "etiqueta" => "22" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Differential diagnosis of cutaneous infiltrates of B lymphocytes with follicular growth pattern" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib0835" "etiqueta" => "23" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T-cell receptor and immunoglobulin gene rearrangements in diagnosing skin disease" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib0840" "etiqueta" => "24" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunophenotyping and gene rearrangement analysis provide additional criteria to differentiate between cutaneous T-cell lymphomas and pseudo-T-cell lymphomas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib0845" "etiqueta" => "25" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoid hyperplasia. Immunologic characteristics and assessment of criteria recently proposed as diagnostic of malignant lymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib0850" "etiqueta" => "26" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Demonstration of clonal immunoglobulin gene rearrangements in cutaneous B-cell lymphomas and pseudo-B-cell lymphomas: Differential diagnostic and pathogenetic aspects" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib0855" "etiqueta" => "27" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lupus profundus, indeterminate lymphocytic lobular panniculitis and subcutaneous T-cell lymphoma: a spectrum of subcuticular T-cell lymphoid dyscrasia" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib0860" "etiqueta" => "28" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: An EORTC Cutaneous Lymphoma Group Study of 83 cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1182/blood-2007-04-087288" "Revista" => array:6 [ …6] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib0865" "etiqueta" => "29" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tattoo ink-related cutaneous pseudolymphoma: A rare but significant complication. Case report and review of the literature" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00266-014-0287-5" "Revista" => array:7 [ …7] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib0870" "etiqueta" => "30" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoid hyperplasia (pseudolymphoma) on the red dye of a tattoo" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.annpat.2013.04.005" "Revista" => array:6 [ …6] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib0875" "etiqueta" => "31" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous B-cell pseudolymphoma at the site of vaccination" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e3181591bea" "Revista" => array:6 [ …6] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib0880" "etiqueta" => "32" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Papulonodular lichenoid and pseudolymphomatous reaction at the injection site of hepatitis B virus vaccination" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "63898" "Revista" => array:6 [ …6] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib0885" "etiqueta" => "33" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphomatous reaction to varicella zoster virus vaccination: Role of viral in situ hybridization" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1600-0560.2009.01461.x" "Revista" => array:6 [ …6] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib0890" "etiqueta" => "34" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multiple pseudolymphomas caused by Hirudo medicinalis therapy" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mjd.2000.110043" "Revista" => array:7 [ …7] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib0895" "etiqueta" => "35" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunohistochemical studies of lymphadenosis benigna cutis occurring in a tattoo" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib0900" "etiqueta" => "36" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphomas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib0905" "etiqueta" => "37" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Skin pseudolymphoma caused by cutaneous leismaniasia" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib0910" "etiqueta" => "38" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Borrelia burgdorferi-associated lymphocytoma cutis: Clinicopathologic, immunophenotypic, and molecular study of 106 cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib0915" "etiqueta" => "39" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic lymphocytoma cutis: A diagnostic dilemma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:3 [ …3] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib0920" "etiqueta" => "40" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Borrelial lymphocytoma--a case report of a pregnant woman" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ttbdis.2012.06.004" "Revista" => array:7 [ …7] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib0925" "etiqueta" => "41" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Miliarial-type perifollicular B-cell pseudolymphoma (lymphocytoma cutis): A misleading eruption in two women" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/cup.12010" "Revista" => array:7 [ …7] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib0930" "etiqueta" => "42" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoma at the dermatology day conference, Paris 2010" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0151-9638(11)70060-6" "Revista" => array:6 [ …6] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib0935" "etiqueta" => "43" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphocytic infiltrations of face" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.clindermatol.2013.05.031" "Revista" => array:7 [ …7] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib0940" "etiqueta" => "44" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Dermatological manifestations of Lyme borreliosis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib0945" "etiqueta" => "45" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acrodermatitis chronica atrophicans with pseudolymphomatous infiltrates" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e31826b7487" "Revista" => array:6 [ …6] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib0950" "etiqueta" => "46" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphomatous folliculitis on the nose" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000336207" "Revista" => array:6 [ …6] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib0955" "etiqueta" => "47" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphomatous folliculitis: A distinctive cutaneous lymphoid hyperplasia" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0019-5154.113937" "Revista" => array:6 [ …6] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib0960" "etiqueta" => "48" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Occult herpesvirus folliculitis clinically simulating pseudolymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib0965" "etiqueta" => "49" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphomatous folliculitis: A clinicopathologic study of 15 cases of cutaneous pseudolymphoma with follicular invasion" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib0970" "etiqueta" => "50" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unusual T cell pseudolymphoma with features of so-called pseudolymphomatous folliculitis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "51843" "Revista" => array:6 [ …6] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib0975" "etiqueta" => "51" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pseudolymphome cutané et pneumopathie interstitielle secondaires à l’association pindolol-allopurinol" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib0980" "etiqueta" => "52" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma induced by adalimumab and reproduced by infliximab in a patient with arthropathic psoriasis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1365-2133.2011.10607.x" "Revista" => array:7 [ …7] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib0985" "etiqueta" => "53" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma due to benidipine hydrochloride with massive infiltration of eosinophils" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib0990" "etiqueta" => "54" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma associated with a TNF-alpha inhibitor treatment: Etanercept" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1684/ejd.2008.0457" "Revista" => array:6 [ …6] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib0995" "etiqueta" => "55" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma following administration of lornoxicam" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2340/00015555-0287" "Revista" => array:6 [ …6] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib1000" "etiqueta" => "56" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid drug reaction secondary to methylphenidate hydrochloride" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib1005" "etiqueta" => "57" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Zoledronic acid-induced cutaneous B-cell pseudolymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2009.04.015" "Revista" => array:6 [ …6] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib1010" "etiqueta" => "58" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous T-cell lymphoma-like drug eruption in an HIV-positive patient taking vancomycin and rifampin" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2310/7750.2013.13047" "Revista" => array:6 [ …6] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib1015" "etiqueta" => "59" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A case of pseudolymphoma syndrome induced by vancomycin" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib1020" "etiqueta" => "60" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma: A rare side effect of cyclosporine" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2014.09.008" "Revista" => array:6 [ …6] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib1025" "etiqueta" => "61" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous targets in drug-induced reactions" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib1030" "etiqueta" => "62" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma with two types of anti-TNFα: A class effect?" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.annder.2012.05.019" "Revista" => array:6 [ …6] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib1035" "etiqueta" => "63" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Severe drug-induced dermatoses" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib1040" "etiqueta" => "64" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Controversies and considerations in the diagnosis of primary cutaneous CD4+ small/medium T-cell lymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5858/arpa.2014-0299-CC" "Revista" => array:6 [ …6] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib1045" "etiqueta" => "65" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Reactive lymphomatoid tissue reactions mimicking cutaneous T and B cell lymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ …4] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib1050" "etiqueta" => "66" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphomas and leukemias" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ …5] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib1055" "etiqueta" => "67" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous Infiltrates–lymphomatous and leukemic" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:5 [ …5] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib1060" "etiqueta" => "68" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carbamazepine-induced pseudo mycosis fungoides" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1345/aph.1D058" "Revista" => array:6 [ …6] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib1065" "etiqueta" => "69" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mycosis fungoides induced by phenytoin" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib1070" "etiqueta" => "70" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical lymphoid infiltrates arising in cutaneous lesions of connective tissue disease" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib1075" "etiqueta" => "71" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unusual histologic presentation of morphea" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ …4] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib1080" "etiqueta" => "72" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acral pseudolymphomatous angiokeratoma: Case report and literature review" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1590/abd1806-4841.20132413" "Revista" => array:6 [ …6] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib1085" "etiqueta" => "73" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acral pseudolymphomatous angiokeratoma. A variant of the cutaneous pseudolymphomas" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib1090" "etiqueta" => "74" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acral pseudolymphomatous angiokeratoma of children: A pseudolymphoma rather than an angiokeratoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib1095" "etiqueta" => "75" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acral pseudolymphomatous angiokeratoma of children (APACHE)" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib1100" "etiqueta" => "76" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T-cell-rich angiomatoid polypoid pseudolymphoma of the skin: a clinicopathologic study of 17 cases and a proposed nomenclature" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1600-0560.2011.01680.x" "Revista" => array:6 [ …6] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib1105" "etiqueta" => "77" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T-cell rich angiomatoid polypoid pseudolymphoma: a novel cutaneous pseudolymphoma" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4103/0019-5154.135486" "Revista" => array:7 [ …7] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib1110" "etiqueta" => "78" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Primary cutaneous angioplasmocellular hyperplasia" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib1115" "etiqueta" => "79" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A pretibial plaque in a five and a half year-old girl" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e3182157efa" "Revista" => array:6 [ …6] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib1120" "etiqueta" => "80" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tibial lymphoplasmacytic plaque: A new, illustrative case of a recently and poorly recognized benign lesion in children" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000341519" "Revista" => array:6 [ …6] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib1125" "etiqueta" => "81" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Isolated benign primary cutaneous plasmacytosis in children: Two illustrative cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2008.596" "Revista" => array:7 [ …7] ] ] ] ] ] 81 => array:3 [ "identificador" => "bib1130" "etiqueta" => "82" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pretibial lymphoplasmacytic plaque in children" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2009.341" "Revista" => array:6 [ …6] ] ] ] ] ] 82 => array:3 [ "identificador" => "bib1135" "etiqueta" => "83" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Nodular secondary syphilis mimicking cutaneous lymphoreticular process" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 83 => array:3 [ "identificador" => "bib1140" "etiqueta" => "84" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Secondary syphilis presenting as pseudolymphoma of the skin" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mjd.2003.329" "Revista" => array:6 [ …6] ] ] ] ] ] 84 => array:3 [ "identificador" => "bib1145" "etiqueta" => "85" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pathologic findings in human scabies" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 85 => array:3 [ "identificador" => "bib1150" "etiqueta" => "86" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ki-1 (CD30) expression in differentiation of lymphomatoid papulosis from arthropod bite reactions" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 86 => array:3 [ "identificador" => "bib1155" "etiqueta" => "87" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cellular hypersensitivity to UV-A: A clue to the aetiology of actinic reticuloid?" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 87 => array:3 [ "identificador" => "bib1160" "etiqueta" => "88" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic reticuloid–photosensitivity or pseudolymphoma?–A review" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 88 => array:3 [ "identificador" => "bib1165" "etiqueta" => "89" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic actinic dermatitis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 89 => array:3 [ "identificador" => "bib1170" "etiqueta" => "90" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic reticuloid. A clinical photobiologic, histopathologic, and follow-up study of 16 patients" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 90 => array:3 [ "identificador" => "bib1175" "etiqueta" => "91" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actinic reticuloid with Sézary cells" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 91 => array:3 [ "identificador" => "bib1180" "etiqueta" => "92" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Immunologic differentiation of the Sézary syndrome due to cutaneous T-cell lymphoma and chronic actinic dermatitis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 92 => array:3 [ "identificador" => "bib1185" "etiqueta" => "93" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The natural history of chronic actinic dermatitis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 93 => array:3 [ "identificador" => "bib1190" "etiqueta" => "94" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Selected inflammatory imitators of mycosis fungoides: Histologic features and utility of ancillary studies" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.5858/arpa.2014-0298-CC" "Revista" => array:6 [ …6] ] ] ] ] ] 94 => array:3 [ "identificador" => "bib1195" "etiqueta" => "95" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lichen sclerosus with histopathologic features simulating early mycosis fungoides" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 95 => array:3 [ "identificador" => "bib1200" "etiqueta" => "96" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Detection of expanded T cell clones in skin biopsy samples of patients with lichen sclerosus et atrophicus by T cell receptor-γ polymerase chain reaction assays" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1046/j.1523-1747.2000.00040.x" "Revista" => array:6 [ …6] ] ] ] ] ] 96 => array:3 [ "identificador" => "bib1205" "etiqueta" => "97" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Solitary nonepidermotropic T cell pseudolymphoma of the skin" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 97 => array:3 [ "identificador" => "bib1210" "etiqueta" => "98" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphomas: Classification and differential diagnosis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 98 => array:3 [ "identificador" => "bib1215" "etiqueta" => "99" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Benign lichenoid keratoses with histologic features of mycosis fungoides: Clinicopathologic description of a clinically significant histologic pattern" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 99 => array:3 [ "identificador" => "bib1220" "etiqueta" => "100" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A proposed new classification system for lichenoid keratosis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 100 => array:3 [ "identificador" => "bib1225" "etiqueta" => "101" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Unilesional mycosis fungoides or lymphomatoid keratosis?" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 101 => array:3 [ "identificador" => "bib1230" "etiqueta" => "102" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis: A syndrome produced by epicutaneous hypersensitivity with clinical features and a histopathologic picture similar to that of mycosis fungoides" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 102 => array:3 [ "identificador" => "bib1235" "etiqueta" => "103" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T cell lymphomatoid contact dermatitis: A challenging case and review of the literature" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/cod.12294" "Revista" => array:6 [ …6] ] ] ] ] ] 103 => array:3 [ "identificador" => "bib1240" "etiqueta" => "104" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Spongiotic simulants of mycosis fungoides" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 104 => array:3 [ "identificador" => "bib1245" "etiqueta" => "105" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis caused by isopropyl-diphenylenediamine: Two cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 105 => array:3 [ "identificador" => "bib1250" "etiqueta" => "106" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis due to ethylenediamine dihydrochloride" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 106 => array:3 [ "identificador" => "bib1255" "etiqueta" => "107" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid-like contact dermatitis from cobalt naphthenate" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 107 => array:3 [ "identificador" => "bib1260" "etiqueta" => "108" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis due to nickel" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 108 => array:3 [ "identificador" => "bib1265" "etiqueta" => "109" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid allergic contact dermatitis from para-phenylenediamine" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 109 => array:3 [ "identificador" => "bib1270" "etiqueta" => "110" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact reaction to gold earrings" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 110 => array:3 [ "identificador" => "bib1275" "etiqueta" => "111" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid eosinophilic reaction to gold earrings" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 111 => array:3 [ "identificador" => "bib1280" "etiqueta" => "112" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphocytoma cutis involving the lower lip" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 112 => array:3 [ "identificador" => "bib1285" "etiqueta" => "113" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous B-cell pseudolymphoma due to paraphenylenediamine" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.dad.0000211500.91499.e3" "Revista" => array:6 [ …6] ] ] ] ] ] 113 => array:3 [ "identificador" => "bib1290" "etiqueta" => "114" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous lymphoid hyperplasia related to squaric acid dibutyl ester" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2009.11.681" "Revista" => array:6 [ …6] ] ] ] ] ] 114 => array:3 [ "identificador" => "bib1295" "etiqueta" => "115" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lymphomatoid contact dermatitis to baby wipes" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/archdermatol.2010.169" "Revista" => array:6 [ …6] ] ] ] ] ] 115 => array:3 [ "identificador" => "bib1300" "etiqueta" => "116" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous CD8+ T-cell infiltrates associated with human immunodeficiency virus" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ad.2011.08.013" "Revista" => array:6 [ …6] ] ] ] ] ] 116 => array:3 [ "identificador" => "bib1305" "etiqueta" => "117" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Regression of CD8+ pseudolymphoma after HIV antiviral triple therapy" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1067/mjd.2003.299" "Revista" => array:6 [ …6] ] ] ] ] ] 117 => array:3 [ "identificador" => "bib1310" "etiqueta" => "118" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "HIV-related CD8+ cutaneous pseudolymphoma: Efficacy of methotrexate" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000346242" "Revista" => array:7 [ …7] ] ] ] ] ] 118 => array:3 [ "identificador" => "bib1315" "etiqueta" => "119" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Rapid clinical change in lesions of atypical cutaneous lymphoproliferative disorder in an HIV patient: A case report and review of the literature" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 119 => array:3 [ "identificador" => "bib1320" "etiqueta" => "120" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polyclonal T-cell expansions in a HIV(+) patient with atypical cutaneous lymphoproliferative disorder, large granular lymphocyte proliferation and SENV infection" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 120 => array:3 [ "identificador" => "bib1325" "etiqueta" => "121" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Atypical cutaneous lymphoproliferative disorder in patients with HIV infection" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 121 => array:3 [ "identificador" => "bib1330" "etiqueta" => "122" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CD30+ lymphomatoid drug reactions" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e31826bc1e5" "Revista" => array:7 [ …7] ] ] ] ] ] 122 => array:3 [ "identificador" => "bib1335" "etiqueta" => "123" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CD30 antigen expression in cutaneous inflammatory infiltrates of scabies: A dynamic immunophenotypic pattern that should be distinguished from lymphomatoid papulosis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 123 => array:3 [ "identificador" => "bib1340" "etiqueta" => "124" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Carbamazepine-induced pseudolymphoma with CD-30 positive cells" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 124 => array:3 [ "identificador" => "bib1345" "etiqueta" => "125" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Infection with parapoxvirus induces CD30-positive cutaneous infiltrates in humans" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 125 => array:3 [ "identificador" => "bib1350" "etiqueta" => "126" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "CD30-positive T-cell-rich pseudolymphoma induced by gold acupuncture" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 126 => array:3 [ "identificador" => "bib1355" "etiqueta" => "127" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma in association with molluscum contagiosum in an elderly patient" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 127 => array:3 [ "identificador" => "bib1360" "etiqueta" => "128" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Face and limb rash in a 58-year-old woman" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.revmed.2014.05.016" "Revista" => array:6 [ …6] ] ] ] ] ] 128 => array:3 [ "identificador" => "bib1365" "etiqueta" => "129" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "IgG4-related skin disease successfully treated by thalidomide: A report of 2 cases with emphasis on pathological aspects" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1001/jamadermatol.2013.2625" "Revista" => array:6 [ …6] ] ] ] ] ] 129 => array:3 [ "identificador" => "bib1370" "etiqueta" => "130" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Isolated cutaneous manifestation of IgG4-related disease" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/jclinpath-2012-200749" "Revista" => array:6 [ …6] ] ] ] ] ] 130 => array:3 [ "identificador" => "bib1375" "etiqueta" => "131" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Case of immunoglobulin G4-related skin disease: Possible immunoglobulin G4-related skin disease cases in cutaneous pseudolymphoma only by immunohistochemical analysis" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/1346-8138.12301" "Revista" => array:6 [ …6] ] ] ] ] ] 131 => array:3 [ "identificador" => "bib1380" "etiqueta" => "132" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma as an alternative presentation of IgG4 related disease" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ …5] ] ] ] ] ] 132 => array:3 [ "identificador" => "bib1385" "etiqueta" => "133" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Annular lichenoid dermatitis of youth" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/S0190" "Revista" => array:6 [ …6] ] ] ] ] ] 133 => array:3 [ "identificador" => "bib1390" "etiqueta" => "134" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Annular lichenoid dermatitis of youth…and beyond: A series of 6 cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/DAD.0b013e31819af679" "Revista" => array:6 [ …6] ] ] ] ] ] 134 => array:3 [ "identificador" => "bib1395" "etiqueta" => "135" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Annular lichenoid dermatitis of youth: A separate entity or on the spectrum of mycosis fungoides? Case report and review of the literature" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/cup.12477" "Revista" => array:6 [ …6] ] ] ] ] ] 135 => array:3 [ "identificador" => "bib1400" "etiqueta" => "136" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A variant of palpable migratory arciform erythema" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 136 => array:3 [ "identificador" => "bib1405" "etiqueta" => "137" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Palpable migratory arciform erythema. Clinical morphology, histopathology, immunohistochemistry, and response to treatment" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 137 => array:3 [ "identificador" => "bib1410" "etiqueta" => "138" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Inflammatory vitiligo-like macules that simulate hypopigmented mycosis fungoides" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ …7] ] ] ] ] ] 138 => array:3 [ "identificador" => "bib1415" "etiqueta" => "139" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cutaneous pseudolymphoma at the site of prior herpes zoster eruption" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 139 => array:3 [ "identificador" => "bib1420" "etiqueta" => "140" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Other lymphoproliferative and myeloproliferative diseases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ …4] ] ] ] ] ] 140 => array:3 [ "identificador" => "bib1425" "etiqueta" => "141" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T-cell clonality in pityriasis lichenoides et varioliformis acuta: A heteroduplex analysis of 20 cases" "autores" => array:1 [ …1] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ …6] ] ] ] ] ] 141 => array:3 [ "identificador" => "bib1430" "etiqueta" => "142" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "T-cell clonality in pityriasis lichenoides: Evidence for a premalignant or reactive immune disorder?" 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Review

Cutaneous Pseudolymphomas

Pseudolinfomas cutáneos

D. Romero-Pérez, M. Blanes Martínez

Corresponding author

blanes_marmar@gva.es

Corresponding author.

, B. Encabo-Durán

Servicio de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain

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          "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Histologic image of the lymphocytoma cutis shown in <a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#46; Dense mixed dermal infiltrate&#46; Note the merging germinal centers devoid of the mantel zone&#44; simulating a B-cell lymphoma &#40;hematoxylin-eosin&#44; original magnification &#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Cutaneous pseudolymphomas are benign reactive lymphoid proliferations that simulate cutaneous lymphomas clinically&#44; histologically&#44; or both clinically and histologically&#46;<a class="elsevierStyleCrossRefs" href="#bib0725"><span class="elsevierStyleSup">1&#8211;6</span></a> The concept was described for the first time in 1891 by Kaposi under the name <span class="elsevierStyleItalic">sarcomatosis cutis</span>&#46; Since then&#44; these proliferations have received many names and the initial descriptions all corresponded to B-cell pseudolymphoma&#46;<a class="elsevierStyleCrossRefs" href="#bib0740"><span class="elsevierStyleSup">4&#44;5&#44;7&#44;8</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Traditionally&#44; cutaneous pseudolymphomas have been classified according to their histologic and immunophenotypic characteristics or rather in relation to the lymphoma they simulate&#46; In other words&#44; they are categorized as cutaneous B-cell pseudolymphomas or cutaneous T-cell pseudolymphomas&#44; depending on the predominant lymphocytic component&#46;<a class="elsevierStyleCrossRef" href="#bib0765"><span class="elsevierStyleSup">9</span></a> While the distinction is frequently artificial&#44; this classification system is still the widely used system for categorizing pseudolymphomas&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">The list of cutaneous pseudolymphomas has grown in recent years with the inclusion of multiple reactive conditions with histopathologic features mimicking those of true lymphomas&#46; It is also noteworthy that several entities that were originally considered to be cutaneous pseudolymphomas have since been reclassified as low-grade lymphomas based on clinical and pathologic findings&#44; molecular biology studies&#44; and follow-up data&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Epidemiological data on cutaneous pseudolymphomas are scarce&#44; although B-cell pseudolymphomas appear to be more common than their T-cell counterparts&#44; and they are also more common in female patients&#46;<a class="elsevierStyleCrossRefs" href="#bib0740"><span class="elsevierStyleSup">4&#44;5&#44;10</span></a> Cutaneous pseudolymphoma generally affects adults&#44; although it can occur at any age&#46; No familial cases have been reported&#46;<a class="elsevierStyleCrossRef" href="#bib0735"><span class="elsevierStyleSup">3</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">The proliferation of skin-associated lymphoid tissue &#40;SALT&#41;&#44; the cutaneous analog of mucosa-associated lymphoid tissue &#40;MALT&#41;&#44; following antigenic stimulation has been proposed as a contributory factor in the pathogenesis of cutaneous pseudolymphoma &#46;<a class="elsevierStyleCrossRef" href="#bib0775"><span class="elsevierStyleSup">11</span></a> Accordingly&#44; cutaneous pseudolymphoma could potentially progress to a true cutaneous lymphoma with permanent antigenic stimulation&#44; as occurs in the gastric mucosa in the presence of persistent <span class="elsevierStyleItalic">Helicobacter pylori</span> infection&#46;<a class="elsevierStyleCrossRef" href="#bib0780"><span class="elsevierStyleSup">12</span></a> However&#44; while there have been some reports of progression to cutaneous lymphoma&#44;<a class="elsevierStyleCrossRefs" href="#bib0785"><span class="elsevierStyleSup">13&#8211;17</span></a> true progression from a correctly diagnosed pseudolymphoma is very rare&#44; if not impossible&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">To diagnose cutaneous pseudolymphoma it is necessary to contrast clinical and histologic findings&#44; with assessment of the architecture and composition of the inflammatory infiltrate&#44; and to complement these findings with immunohistochemistry and gene rearrangement studies&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;18&#44;19</span></a> These clonality studies generally reveal a polyclonal pattern&#46; Nevertheless&#44; it is not always possible to demonstrate clonality in true lymphomas&#44; and certain pseudolymphomas have monoclonal B-cell and T-cell populations&#46;<a class="elsevierStyleCrossRefs" href="#bib0745"><span class="elsevierStyleSup">5&#44;8&#44;20&#8211;26</span></a> Accordingly&#44; although gene arrangement studies are useful&#44; their results must be interpreted with caution and within the context of the data available&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">In the rest of this paper we will describe the main types of cutaneous pseudolymphoma &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Lupus Erythematosus Panniculitis</span><p id="par0040" class="elsevierStylePara elsevierViewall">Lupus with subcutaneous involvement&#44; a condition known as lupus erythematosus panniculitis&#44; can raise clinical and particularly histologic suspicions of panniculitis-like T-cell lymphoma&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;27</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Lupus erythematosus panniculitis presents as plaques or subcutaneous nodules in areas rarely affected by other forms of panniculitis&#44; such as the face&#44; the shoulders&#44; and the proximal aspect of the arms&#46; Antinuclear antibodies and other diagnostic criteria for systemic lupus erythematosus may be absent&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Histologic examination shows a predominantly lobular panniculitis with dense lymphoid infiltrates in the deep dermis and the hypodermis&#44; along with wide fibrous septae on occasions&#46; The infiltrate is mixed&#44; with abundant B cells&#44; plasma cells&#44; and clusters of plasmacytoid dendritic cells&#44; frequently forming reactive germinal centers&#46; The dermal-epidermal junction may show the characteristic interface dermatitis associated with the underlying connective tissue disease&#44; and this is a key finding for the differential diagnosis&#46; In lupus erythematosus panniculitis&#44; unlike in panniculitis-like T-cell lymphoma&#44; histology does not show cytophagocytosis or adipocyte rimming &#40;atypical lymphoid cells surrounding the adipocytes&#41;&#46; T-cell receptor &#40;<span class="elsevierStyleItalic">TCR</span>&#41; gene rearrangement will show a polyclonal pattern&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;27</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">Histologic features of panniculitis-like T-cell lymphoma and lupus erythematosus panniculitis may&#44; albeit rarely&#44; overlap&#46; In one study of 83 patients with panniculitis-like T-cell lymphoma&#44; Willemze et al&#46;<a class="elsevierStyleCrossRef" href="#bib0860"><span class="elsevierStyleSup">28</span></a> observed abundant plasma cells interspersed with CD4<span class="elsevierStyleSup">&#43;</span> T cells in 4 patients who also had lupus erythematosus&#44; leading to an initial misdiagnosis of lupus erythematous panniculitis&#46; The presence of cellular atypia together with a loss of pan-T-cell markers and&#47;or clonal TCR-&#947; rearrangement was key to establishing a correct diagnosis&#46;<a class="elsevierStyleCrossRef" href="#bib0860"><span class="elsevierStyleSup">28</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Pseudolymphoma in Tattoos</span><p id="par0060" class="elsevierStylePara elsevierViewall">Although uncommon&#44; pseudolymphomatous reactions to tattoo ink can occur&#44; and a variable latency period has been described&#46;<a class="elsevierStyleCrossRefs" href="#bib0865"><span class="elsevierStyleSup">29&#44;30</span></a> Red ink is the most common ink involved in these reactions&#46;<a class="elsevierStyleCrossRef" href="#bib0870"><span class="elsevierStyleSup">30</span></a> Tattoo ink&#8211;related pseudolymphoma presents as subcutaneous nodules&#46;<a class="elsevierStyleCrossRef" href="#bib0775"><span class="elsevierStyleSup">11</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">Histologic examination shows a dense diffuse dermal infiltrate with perivascular and periadnexal accentuation composed mainly of small lymphocytes &#40;most often T cells but there may also be B cells or a mixture&#41; and macrophages&#46; Additional findings include eosinophils&#44; plasma cells&#44; histiocytes&#44; and giant multinucleated cells&#46; These cells may form lymphoid follicles with germinal centers or patterns similar to those seen in mycosis fungoides&#46; Spongiosis&#44; exocytosis&#44; and basal vacuolar degeneration may also be observed in the epidermis&#46;<a class="elsevierStyleCrossRefs" href="#bib0865"><span class="elsevierStyleSup">29&#44;30</span></a> The presence of macrophages phagocytizing the pigment is a key diagnostic clue&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Pseudolymphoma at the Site of Vaccination</span><p id="par0070" class="elsevierStylePara elsevierViewall">An intense inflammatory response simulating cutaneous lymphoma can also occur at vaccination sites as the result of a delayed hypersensitivity reaction to vaccine components&#46; This reaction is particularly seen in vaccines containing aluminum&#44; as this metal contributes to the delayed absorption of other components&#44; thereby prolonging the antigen stimulus&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;31</span></a> It presents as papules or superficial or deep erythematous nodules&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;32</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">The histologic pattern may be lichenoid&#44; simulating mycosis fungoides&#44; or nodular&#44; simulating follicle center lymphoma &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; In this second case&#44; however&#44; bcl-6<span class="elsevierStyleSup">&#43;</span> cells will not be observed outside the reactive germinal centers&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;33</span></a> Clusters of CD30<span class="elsevierStyleSup">&#43;</span> cells may occasionally be observed&#46;<a class="elsevierStyleCrossRef" href="#bib0885"><span class="elsevierStyleSup">33</span></a> When aluminum is involved&#44; the histiocytes in the infiltrate&#44; which may be solitary or arranged in clusters forming epithelioid granulomas&#44; typically have abundant granular and basophilic cytoplasm &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; corresponding to intracellular aluminum deposits&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Lymphocytoma Cutis</span><p id="par0080" class="elsevierStylePara elsevierViewall">Lymphocytoma cutis was first described by Spiegler in 1894&#46; It is the prototype of cutaneous B-cell pseudolymphoma and perhaps the most common variant&#46; It represents an exaggerated local immune response to diverse stimuli&#44; the most widely described of which are arthropod bites&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;32&#8211;37</span></a> One of the most classic associations is with the spirochete <span class="elsevierStyleItalic">Borrelia burgdorferi</span> following a bite from a <span class="elsevierStyleItalic">Ixodes</span> tick&#46;<a class="elsevierStyleCrossRefs" href="#bib0830"><span class="elsevierStyleSup">22&#44;38</span></a></p><p id="par0085" class="elsevierStylePara elsevierViewall">Lymphocytoma cutis typically presents as a solitary reddish nodule &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; or less frequently as plaques or crops of papules&#46; The face and neck are the most common sites of involvement&#46; Lesions on the earlobe&#44; nipples&#44; or scrotum are highly characteristic of <span class="elsevierStyleItalic">B&#160;burgdorferi</span>&#8211;associated lymphocytoma cutis&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;38&#8211;40</span></a></p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall">Miliarial-type lesions have also been described&#44; but less frequently&#46; These present as multiple&#44; symmetric&#44; monomorphous translucent micropapules on the head and neck and they can be asymptomatic or slightly pruritic&#46;<a class="elsevierStyleCrossRefs" href="#bib0775"><span class="elsevierStyleSup">11&#44;41&#44;42</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">Histology reveals a dense nodular lymphoid infiltrate in the dermis&#44; with germinal centers that characteristically lack a mantle zone and may merge&#46; Although the infiltrate in pseudolymphomas tends to be top heavy &#40;i&#46;e&#46;&#44; more pronounced in the superficial dermis&#41; rather than bottom heavy like in lymphomas&#44; in <span class="elsevierStyleItalic">B&#160;burgdorferi</span>&#8211;associated lymphocytoma cutis&#44; infiltrates are often found throughout the dermis and even in the superficial layers of the subcutaneous tissue&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a></p><p id="par0100" class="elsevierStylePara elsevierViewall">The infiltrate is formed by plasma cells&#44; eosinophils&#44; abundant reactive T cells&#44; and tingible body macrophages &#40;<a class="elsevierStyleCrossRef" href="#fig0020">Fig&#46; 4</a>&#41;&#46; This heterogeneity is another factor to take into account when distinguishing cutaneous pseudolymphomas from true lymphomas&#44; as these tend to have a more uniform infiltrate&#46; The predominant immunophenotype is a germinal center B-cell type&#44; with positive staining for CD20&#44; CD10&#44; and bcl-6&#44; and negative staining for bcl-2&#46; The germinal centers tend to have a very high proliferative index&#44; but unlike in true cutaneous lymphomas&#44; cellular atypia and preservation of adnexal structures are not observed&#46; Rearrangement analysis usually&#44; but not always&#44; shows a polyclonal pattern&#46; Assessment of clonality in more than 1 lesion is very useful for differentiating pseudolymphomas and lymphomas in patients with several lesions&#46; Detection of the same clone in 2 lesions or in the same lesion at different stages of development would point to a diagnosis of lymphoma&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;39&#44;43</span></a></p><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Pseudolymphoma in Acrodermatitis Chronica Atrophicans Lesions</span><p id="par0105" class="elsevierStylePara elsevierViewall">Pseudolymphoma has been described in the lesions of patients with acrodermatitis chronica atrophicans&#44; which is a delayed cutaneous manifestation of <span class="elsevierStyleItalic">B burgdorferi</span> infection&#46; Histologically&#44; lesions can display 2 patterns&#58; one simulating mycosis fungoides and the other &#40;less frequent&#41; one simulating cutaneous B-cell lymphoma&#46; The rearrangement study shows a polyclonal infiltrate&#46;<a class="elsevierStyleCrossRefs" href="#bib0940"><span class="elsevierStyleSup">44&#44;45</span></a></p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Pseudolymphomatous Folliculitis</span><p id="par0110" class="elsevierStylePara elsevierViewall">Pseudolymphomatous folliculitis is a cutaneous pseudolymphoma characterized by the presence of hyperplastic hair follicles together with a lymphoid infiltrate that can mimic cutaneous lymphoma&#46; It presents with a single or&#44; less frequently&#44; several dome-shaped or nodular lesions on the face&#44; scalp&#44; or trunk&#46;<a class="elsevierStyleCrossRefs" href="#bib0780"><span class="elsevierStyleSup">12&#44;46</span></a></p><p id="par0115" class="elsevierStylePara elsevierViewall">Histologically&#44; pseudolymphomatous folliculitis can simulate small-to-medium-sized pleomorphic T-cell lymphoma&#44; follicle center B-cell lymphoma&#44; or even folliculotropic mycosis fungoides&#46; A dense lymphocytic infiltrate is located predominantly around the hair follicles&#44; which show hyperplastic changes and thickened walls&#46; Clusters of perifollicular S100<span class="elsevierStyleSup">&#43;</span> and CD1A<span class="elsevierStyleSup">&#43;</span> histiocytes may occasionally be seen&#46; Rearrangement studies show a polyclonal infiltrate&#46;<a class="elsevierStyleCrossRefs" href="#bib0775"><span class="elsevierStyleSup">11&#44;12&#44;46&#8211;50</span></a></p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Lymphomatoid Drug Reaction</span><p id="par0120" class="elsevierStylePara elsevierViewall">Numerous drugs can induce cutaneous lymphoid infiltrates that resemble lymphoma clinically&#44; histologically&#44; or both clinically and histologically&#46; The most frequently implicated drugs are anticonvulsants and antihypertensives&#44; but others have been described &#40;<a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#41;&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0125" class="elsevierStylePara elsevierViewall">Clinically&#44; lymphomatoid drug reactions present as generalized papules&#44; plaques&#44; or nodules&#44; or even erythroderma&#44; sometimes with accentuation in sun-exposed areas&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;36&#44;61</span></a> Lesions typically appear 2 to 8 weeks after the introduction of the offending drug&#44; but later onset has been reported&#46;<a class="elsevierStyleCrossRefs" href="#bib0900"><span class="elsevierStyleSup">36&#44;42&#44;62</span></a> The skin lesions may be accompanied by enlarged lymph nodes&#44; fever&#44; and less frequently hepatosplenomegaly&#44; joint pain&#44; and diverse blood test alterations including elevated liver enzymes and eosinophilia&#44; particularly in cases due to anticonvulsants&#46;<a class="elsevierStyleCrossRefs" href="#bib1025"><span class="elsevierStyleSup">61&#44;63</span></a> Circulating S&#233;zary cells may occasionally be detected&#46;<a class="elsevierStyleCrossRef" href="#bib0900"><span class="elsevierStyleSup">36</span></a></p><p id="par0130" class="elsevierStylePara elsevierViewall">Histologic findings in lymphomatoid drug reaction include a band-like T&#160;cell&#8211;predominant infiltrate with epidermal spongiosis and exocytosis&#44; simulating mycosis fungoides&#46; On other occasions&#44; there may be a nodular or diffuse B-cell pattern with formation of germinal centers&#44; simulating follicle center or marginal zone B-cell lymphoma&#46; Cellular atypia has been described in some cases&#44; as have abundant CD30<span class="elsevierStyleSup">&#43;</span> cells&#44; which can complicate diagnosis&#46; Findings suggestive of lymphomatoid drug reaction include necrotic keratinocytes&#44; red blood cell extravasation&#44; pigmentary incontinence&#44; dermal edema&#44; absence of fibrosis in the papillary dermis&#44; presence of other inflammatory cells in the infiltrate&#44; and finally&#44; negative clonality in the gene rearrangement study&#46; Lesions in sun-exposed areas can also point to a diagnosis of lymphomatoid drug reaction&#46;<a class="elsevierStyleCrossRefs" href="#bib0930"><span class="elsevierStyleSup">42&#44;43&#44;61&#44;64&#8211;68</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">The condition resolves after a variable period of time on withdrawal of the drug and returns when it is reintroduced&#46;<a class="elsevierStyleCrossRefs" href="#bib0930"><span class="elsevierStyleSup">42&#44;43</span></a> There have been very rare reports of progression to true cutaneous lymphoma&#44;<a class="elsevierStyleCrossRef" href="#bib1065"><span class="elsevierStyleSup">69</span></a> and in these cases the skin lesions would not disappear after withdrawal of the drug&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Morphea</span><p id="par0140" class="elsevierStylePara elsevierViewall">Collagen involvement is often not very evident in the inflammatory phase of connective tissue disorders&#44; especially in localized scleroderma&#44; and histology may reveal dense lymphoid infiltrates simulating cutaneous lymphoma and marginal zone B-cell lymphoma in particular&#46; Plasma cells are almost always present and light chain gene rearrangement studies will show a polyclonal infiltrate&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;70&#44;71</span></a> It is essential to contrast clinical and pathologic findings in such cases&#46;</p></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Acral Pseudolymphomatous Angiokeratoma&#47;Small Papular Pseudolymphoma</span><p id="par0145" class="elsevierStylePara elsevierViewall">Acral pseudolymphomatous angiokeratoma&#44; which was originally described under the acronym APACHE &#40;acral pseudolymphoma angiokeratoma in children&#41;&#44; is a rare benign condition of unknown etiology and pathogenesis&#44; although some authors believe it is a hypersensitivity reaction to insect bites&#46;<a class="elsevierStyleCrossRefs" href="#bib0740"><span class="elsevierStyleSup">4&#44;6&#44;72&#44;73</span></a> It is characterized by papules or clusters of asymptomatic red-purple nodules&#44; typically located at acral sites&#44; and is more common in children and adolescents&#46;<a class="elsevierStyleCrossRefs" href="#bib0775"><span class="elsevierStyleSup">11&#44;36&#44;72&#8211;75</span></a></p><p id="par0150" class="elsevierStylePara elsevierViewall">Histologic findings include a dense well-differentiated nodular B-cell and T-cell infiltrate that generally spares the adnexal structures&#44; in addition to plasma cells&#44; eosinophils&#44; and on occasions histiocytes and giant multinucleated cells&#46; A proliferation of capillary vessels may be observed&#46; The epidermis is normally spared&#44; although there have been reports of basal vacuolization&#44; exocytosis&#44; and spongiosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;72</span></a></p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">T Cell&#8211;Rich Angiomatoid Polypoid Pseudolymphoma</span><p id="par0155" class="elsevierStylePara elsevierViewall">T cell&#8211;rich angiomatoid polypoid pseudolymphoma has similar histologic findings to acral pseudolymphomatous angiokeratoma&#44; but it is characterized by solitary polypoid lesions at nonacral sites&#44; with a predilection for the head and trunk&#46; It typically affects young adults&#46;<a class="elsevierStyleCrossRefs" href="#bib0775"><span class="elsevierStyleSup">11&#44;76&#44;77</span></a> Another difference between the 2 entities is that in angiomatoid polypoid pseudolymphoma&#44; there is a predominance of CD4<span class="elsevierStyleSup">&#43;</span> T cells in the infiltrate and the prominent thick-walled vessels seen in acral pseudolymphomatous angiokeratoma are absent&#46; Both entities must be distinguished from angioplasmacellular hyperplasia&#44; in which the infiltrate is much richer in plasma cells&#46;<a class="elsevierStyleCrossRefs" href="#bib1100"><span class="elsevierStyleSup">76&#8211;78</span></a></p></span><span id="sec0060" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Pretibial Lymphoplasmacytic Plaque in Children</span><p id="par0160" class="elsevierStylePara elsevierViewall">Pretibial lymphoplasmacytic plaque is a benign chronic condition of unknown etiology that is probably reactive in nature&#46; It presents as red-purple asymptomatic papules or well-delimited plaques that preferentially affect the anterior surface of the tibia in children&#46; Histologically&#44; it is similar to acral pseudolymphomatous angiokeratoma&#44; although there is a much more pronounced presence of plasma cells&#44; together with lymphocytes and prominent vessels&#46; Vacuolization&#44; exocytosis&#44; and apoptotic bodies may be observed in the epidermis&#46; The gene rearrangement study shows a polyclonal pattern&#46;<a class="elsevierStyleCrossRefs" href="#bib1115"><span class="elsevierStyleSup">79&#8211;82</span></a></p></span><span id="sec0065" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Secondary Syphilis</span><p id="par0165" class="elsevierStylePara elsevierViewall">Histology of secondary syphilis lesions and less frequently of primary or tertiary syphilis lesions may occasionally reveal a lymphoplasmacytic infiltrate simulating marginal zone B-cell cutaneous lymphoma&#46; The coexistence of interface&#47;lichenoid dermatitis or granulomatous inflammation is an important diagnostic clue&#46; Rearrangement studies show a polyclonal pattern and specific immunohistochemical staining for <span class="elsevierStyleItalic">Treponema pallidum</span> confirms the presence of these organisms&#46; Lesions resolve quickly with antibiotic treatment&#46; It is also worth noting that certain cases of malignant syphilis may also feature lesions that are clinically indistinguishable from lymphomatoid papulosis&#46; The entities are also difficult to differentiate histologically&#44; unless abundant plasma cells and spirochetes are observed&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;83&#44;84</span></a></p></span><span id="sec0070" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Persistent Arthropod Bite Reaction</span><p id="par0170" class="elsevierStylePara elsevierViewall">Nodular scabies is the paradigm of persistent arthropod bite reaction&#44; although this can be caused by arthropods other than the scabies mite&#46; A delayed hypersensitivity reaction to a component of the mite has been implicated in the pathogenesis of the reaction&#44; although it is rarely identified in lesions&#46; Clinically&#44; arthropod bite reaction presents as reddish papules or persistent pruritic nodules&#44; despite adequate treatment&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;36</span></a></p><p id="par0175" class="elsevierStylePara elsevierViewall">Histologically&#44; nodular scabies may simulate mycosis fungoides&#44; lymphomatoid papulosis&#44; Hodgkin lymphoma&#44; and in some cases&#44; cutaneous B-cell lymphoma&#46; The most frequent finding is a dense perivascular superficial and deep lymphoid infiltrate with predominant T cells&#44; which are frequently CD30<span class="elsevierStyleSup">&#43;</span>&#44; together with plasma cells&#44; eosinophils&#44; and prominent vessels&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;12&#44;36&#44;85&#44;86</span></a></p></span><span id="sec0075" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Actinic Reticuloid</span><p id="par0180" class="elsevierStylePara elsevierViewall">Actinic reticuloid is a chronic photodermatitis that tends to affect elderly patients&#44; and men in particular&#46; It is characterized by extreme photosensitivity across a wide spectrum of UV radiation&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;36&#44;43&#44;87</span></a> Its pathogenesis remains unclear&#44; although it has been proposed that a normal component of skin might become antigenic following alterations induced by a photoallergic reaction&#46;<a class="elsevierStyleCrossRefs" href="#bib1160"><span class="elsevierStyleSup">88&#44;89</span></a></p><p id="par0185" class="elsevierStylePara elsevierViewall">In its early phases&#44; actinic reticuloid presents as a highly pruritic eczematous dermatitis&#59; there is a tendency towards localized lichenification in sun-exposed areas that may then spread to other areas&#46;<a class="elsevierStyleCrossRefs" href="#bib0900"><span class="elsevierStyleSup">36&#44;88</span></a> Histology reveals a mixed perivascular superficial or deep infiltrate that may include some atypical mononuclear cells&#46; Actinic reticuloid can form a band-like pattern with lymphocytic exocytosis&#44; simulating mycosis fungoides&#44; or a more diffuse pattern&#44; simulating peripheral T-cell lymphoma&#46; The CD4&#47;CD8 ratio&#44; however&#44; is lower in the case of actinic reticuloid&#46;<a class="elsevierStyleCrossRefs" href="#bib0900"><span class="elsevierStyleSup">36&#44;43&#44;88</span></a></p><p id="par0190" class="elsevierStylePara elsevierViewall">As the condition progresses&#44; patients may develop erythroderma&#44; enlarged lymph nodes&#44; ectropion and up to 10&#37; of S&#233;zary cells in peripheral blood&#44; complicating the differential diagnosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;36&#44;90&#8211;92</span></a> Unlike mycosis fungoides and S&#233;zary syndrome&#44; sensitivity to UV-B&#44; UV-A&#44; and even visible light is very high and can exacerbate the condition&#46;<a class="elsevierStyleCrossRef" href="#bib1160"><span class="elsevierStyleSup">88</span></a></p><p id="par0195" class="elsevierStylePara elsevierViewall">Actinic reticuloid is a chronic condition that does not tend to resolve spontaneously&#46;<a class="elsevierStyleCrossRefs" href="#bib0935"><span class="elsevierStyleSup">43&#44;93</span></a> Sun-protection measures are essential&#44; as is avoidance of implicated allergens&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a></p></span><span id="sec0080" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Lichen Sclerosus</span><p id="par0200" class="elsevierStylePara elsevierViewall">Genital lichen sclerosus&#44; particularly in its early phases&#44; has histologic features that require consideration of mycosis fungoides in the differential diagnosis&#46; Lesions show a dense band-like lymphoid infiltrate in the superficial dermis and marked epidermotropism&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;94</span></a> To confuse matters even further&#44; gene rearrangement studies reveal a clonal pattern in a considerable number of cases&#46;<a class="elsevierStyleCrossRefs" href="#bib1195"><span class="elsevierStyleSup">95&#44;96</span></a> Cellular atypia is not generally seen in the infiltrate in lichen sclerosus&#44; and intraepidermal lymphocytes tend to be located in the lower part of the epidermis&#44; without pagetoid spread&#59; interface changes are also common&#46;<a class="elsevierStyleCrossRef" href="#bib1190"><span class="elsevierStyleSup">94</span></a> It is essential to contrast clinical and pathologic findings&#46;</p></span><span id="sec0085" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Lichen Aureus</span><p id="par0205" class="elsevierStylePara elsevierViewall">Lichen aureus also has histologic features that can be confused with mycosis fungoides&#44; and in some cases&#44; there may be molecular evidence of clonality&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a> Again&#44; it is important to carefully correlate clinical and pathologic findings&#46;</p></span><span id="sec0090" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Solitary T-Cell Pseudolymphoma</span><p id="par0210" class="elsevierStylePara elsevierViewall">Solitary T-cell pseudolymphoma is one of the most controversial variants of pseudolymphoma&#46; With histologic features similar to those of mycosis fungoides and occasional monoclonality&#44; this entity can present as superficial lesions on the breasts of adult women that resemble lichenoid keratosis lesions&#46; In other cases&#44; it appears as solitary nodular lesions with histologic findings similar to those of small- to-medium-sized pleomorphic T-cell lymphoma&#46; It follows an indolent course and excision is curative&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;97&#44;98</span></a></p></span><span id="sec0095" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Lichenoid Keratosis</span><p id="par0215" class="elsevierStylePara elsevierViewall">Lichenoid keratosis is a benign epithelial tumor related to seborrheic keratosis and lentigines that affects elderly patients&#46; It appears as small scaling plaques normally located on the trunk&#46; Histologically&#44; the findings can simulate those of mycosis fungoides&#44; with a dense band-like lymphocytic infiltrate with a certain degree of epidermotropism and occasional monoclonality&#46; Clinical-pathologic correlation is essential&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;99&#8211;101</span></a></p></span><span id="sec0100" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Lymphomatoid Contact Dermatitis</span><p id="par0220" class="elsevierStylePara elsevierViewall">Described for the first time by Orbaneja et al&#46;<a class="elsevierStyleCrossRef" href="#bib1230"><span class="elsevierStyleSup">102</span></a> in 1976&#44; lymphomatoid contact dermatitis has similar clinical and histopathologic features to mycosis fungoides&#46; It presents as pruritic erythematous plaques&#44; with an oscillating course&#44; and is more common in middle-aged men&#46;<a class="elsevierStyleCrossRefs" href="#bib1230"><span class="elsevierStyleSup">102&#8211;104</span></a> Histology shows a band-like T cell&#8211;predominant infiltrate component and epidermotropism &#40;<a class="elsevierStyleCrossRef" href="#fig0025">Fig&#46; 5</a>&#41;&#46; However&#44; in the epidermis there may be spongiosis or microvesiculation&#59; cellular atypia is very low and there is no evidence of Pautrier microabscesses&#44; although it is not uncommon to see small collections of keratinocytes intermixed with Langerhans cells and some lymphocytes that are frequently confused with keratinocytes &#40;<a class="elsevierStyleCrossRef" href="#fig0030">Fig&#46; 6</a>&#41;&#46; TCR rearrangement studies generally show a polyclonal infiltrate&#46;<a class="elsevierStyleCrossRefs" href="#bib0935"><span class="elsevierStyleSup">43&#44;94&#44;103&#44;104</span></a></p><elsevierMultimedia ident="fig0025"></elsevierMultimedia><elsevierMultimedia ident="fig0030"></elsevierMultimedia><p id="par0225" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a> shows the allergens that have been implicated in lymphomatoid contact dermatitis&#46;<a class="elsevierStyleCrossRefs" href="#bib1230"><span class="elsevierStyleSup">102&#44;105&#8211;115</span></a> Patch tests show sensitization<a class="elsevierStyleCrossRef" href="#bib1235"><span class="elsevierStyleSup">103</span></a> and the condition resolves with avoidance of exposure to causative allergens&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a></p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span><span id="sec0105" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Atypical CD8<span class="elsevierStyleSup">&#43;</span> Lymphoid Proliferation in Patients With Human Immunodeficiency Virus</span><p id="par0230" class="elsevierStylePara elsevierViewall">Atypical CD8<span class="elsevierStyleSup">&#43;</span> lymphoid proliferation is a polyclonal lymphoproliferative disorder with an apparently reactive nature that is clinically and histologically similar to T-cell lymphoma and affects individuals with human immunodeficiency virus infection&#44; particularly when they are severely immunocompromised&#46; Its pathogenesis is unknown&#46;<a class="elsevierStyleCrossRef" href="#bib1300"><span class="elsevierStyleSup">116</span></a></p><p id="par0235" class="elsevierStylePara elsevierViewall">Clinically&#44; it presents as a generalized pruritic rash frequently associated with pigment changes &#40;hypopigmentation or hyperpigmentation&#41; and lichenification&#46; Lymphadenopathy&#44; splenomegaly&#44; eosinophilia&#44; and&#44; on occasions&#44; circulating S&#233;zary cells have also been described&#46;<a class="elsevierStyleCrossRefs" href="#bib1300"><span class="elsevierStyleSup">116&#8211;118</span></a></p><p id="par0240" class="elsevierStylePara elsevierViewall">The histologic features resemble those of mycosis fungoides&#44; but there is a predominance of CD8<span class="elsevierStyleSup">&#43;</span> lymphocytes&#46; Clonality studies are negative&#46;<a class="elsevierStyleCrossRefs" href="#bib1300"><span class="elsevierStyleSup">116&#44;119&#8211;121</span></a></p></span><span id="sec0110" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0130">CD30<span class="elsevierStyleSup">&#43;</span> T-Cell Pseudolymphoma</span><p id="par0245" class="elsevierStylePara elsevierViewall">The presence of large atypical CD30<span class="elsevierStyleSup">&#43;</span> T cells has been described in numerous reactive skin disorders in recent years &#40;<a class="elsevierStyleCrossRef" href="#tbl0020">Table 4</a>&#41;&#46; In these pseudolymphomas&#44; CD30<span class="elsevierStyleSup">&#43;</span> cells do not form clusters but are rather distributed throughout the infiltrate&#46; Rearrangement studies show a polyclonal pattern&#46; Histology frequently shows evidence of the underlying condition&#46;<a class="elsevierStyleCrossRefs" href="#bib0750"><span class="elsevierStyleSup">6&#44;122</span></a></p><elsevierMultimedia ident="tbl0020"></elsevierMultimedia></span><span id="sec0115" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0135">Immunoglobulin G4&#8211;Related Sclerosing Disease</span><p id="par0250" class="elsevierStylePara elsevierViewall">Immunoglobulin &#40;Ig&#41; G4-related sclerosing disease is characterized by a lymphoplasmacytic infiltrate featuring IgG4<span class="elsevierStyleSup">&#43;</span> plasma cells&#44; together with sclerotic changes and elevated IgG4 serum levels &#40;&#62;135<span class="elsevierStyleHsp" style=""></span>mg&#47;dL&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib1360"><span class="elsevierStyleSup">128</span></a></p><p id="par0255" class="elsevierStylePara elsevierViewall">Skin involvement is rare&#44; but it can occur in isolation and without elevated serum IgG4 titers&#46; IgG4-related sclerosing disease presents as plaques or as solitary or multiple nodules on the head and&#47;or extremities of middle-aged&#44; predominantly male&#44; adults&#46;<a class="elsevierStyleCrossRefs" href="#bib1365"><span class="elsevierStyleSup">129&#8211;132</span></a></p><p id="par0260" class="elsevierStylePara elsevierViewall">Histology shows a mixed inflammatory infiltrate immersed in a sclerotic stroma in the dermis&#44; and occasionally in the subcutaneous tissue&#46;<a class="elsevierStyleCrossRefs" href="#bib0775"><span class="elsevierStyleSup">11&#44;128&#44;130</span></a> An IgG4 to total IgG ratio of above 40&#37; is highly suggestive of IgG4-related sclerosing disease&#46;<a class="elsevierStyleCrossRef" href="#bib1360"><span class="elsevierStyleSup">128</span></a></p></span><span id="sec0120" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0140">Annular Lichenoid Dermatitis</span><p id="par0265" class="elsevierStylePara elsevierViewall">Annular lichenoid dermatitis is an entity of unknown pathogenesis&#44; initially described in children&#44; that shares many histologic and immunophenotypic characteristics with mycosis fungoides&#46; It presents as solitary or multiple asymptomatic reddish-brown annular plaques with raised borders on the trunk&#46;</p><p id="par0270" class="elsevierStylePara elsevierViewall">Histologic examination shows a band-like CD8<span class="elsevierStyleSup">&#43;</span>-predominant lymphocytic infiltrate&#44; vacuolar degeneration at the dermal-epidermal junction&#44; and necrotic keratinocytes at the tips of the rete ridges&#46; Marked epidermotropism&#44; Pautrier microabscesses&#44; and fibrosis in the papillary dermis are not observed&#46; Monoclonality is shown to be absent by rearrangement studies&#46;<a class="elsevierStyleCrossRefs" href="#bib1385"><span class="elsevierStyleSup">133&#8211;135</span></a></p></span><span id="sec0125" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0145">Palpable Migratory Arciform Erythema</span><p id="par0275" class="elsevierStylePara elsevierViewall">Palpable migratory arciform erythema is an uncommon entity that presents with erythematous annular plaques located predominantly on the trunk with a centrifugal distribution&#59; the lesions tend to disappear within days or weeks&#46; Histologically there is a perivascular and periadnexal CD4<span class="elsevierStyleSup">&#43;</span>-predominant lymphocytic infiltrate&#44; without epidermal involvement&#44; plasma cells&#44; or interstitial mucin&#46; A polyclonal pattern is detected by gene rearrangement studies in most cases&#46;<a class="elsevierStyleCrossRefs" href="#bib1400"><span class="elsevierStyleSup">136&#44;137</span></a></p></span><span id="sec0130" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0150">Other Cutaneous Pseudolymphomas</span><p id="par0280" class="elsevierStylePara elsevierViewall">Other cutaneous pseudolymphomas can also simulate cutaneous lymphomas clinically and&#47;or histologically&#46;</p><p id="par0285" class="elsevierStylePara elsevierViewall">In the inflammatory phase of vitiligo&#44; which is characterized by erythematous&#44; scaling plaques rather than achromic patches&#44; histology can reveal a dense band-like lichenoid infiltrate with lymphocytic exocytosis simulating mycosis fungoides in the lower part of the epidermis&#46; Most of the cells are CD8<span class="elsevierStyleSup">&#43;</span>&#46; Follow-up is essential&#46;<a class="elsevierStyleCrossRef" href="#bib1410"><span class="elsevierStyleSup">138</span></a></p><p id="par0290" class="elsevierStylePara elsevierViewall">There have also been reports of pseudolymphomas in relation to herpes simplex and herpes zoster infections that can mimic T-cell or B-cell lymphomas or CD30<span class="elsevierStyleSup">&#43;</span> lymphoproliferative diseases&#46;<a class="elsevierStyleCrossRef" href="#bib1415"><span class="elsevierStyleSup">139</span></a></p><p id="par0295" class="elsevierStylePara elsevierViewall">Atypical cells have also been described in cases of chronic discoid lupus erythematosus&#46;<a class="elsevierStyleCrossRef" href="#bib0750"><span class="elsevierStyleSup">6</span></a> Jessner lymphocytic infiltrate of the skin can also be histologically confused with B-cell lymphoma&#46; Polyclonal infiltrates and CD123<span class="elsevierStyleSup">&#43;</span> plasmacytoid monocytes can help to distinguish between these disorders&#46;<a class="elsevierStyleCrossRefs" href="#bib0935"><span class="elsevierStyleSup">43&#44;140</span></a></p><p id="par0300" class="elsevierStylePara elsevierViewall">The true nature of pityriasis lichenoides et varioliformis acuta &#40;PLEVA&#41; is still a matter of debate&#46; PLEVA is a generally benign condition and is probably a reactive disorder with an infectious or inflammatory origin&#46;<a class="elsevierStyleCrossRefs" href="#bib1425"><span class="elsevierStyleSup">141&#8211;143</span></a> However&#44; there have been reports of monoclonal rearrangement<a class="elsevierStyleCrossRef" href="#bib1425"><span class="elsevierStyleSup">141</span></a> and&#44; at least in the febrile ulceronecrotic form&#44; an association with cytotoxic cutaneous lymphoma has been considered&#46; The 2 entities have overlapping clinical and histologic findings&#44; although infiltrates are not as dense or as deep in PLEVA&#44; and cellular atypia is also less pronounced&#46;<a class="elsevierStyleCrossRef" href="#bib1440"><span class="elsevierStyleSup">144</span></a> Follow-up is particularly important in PLEVA&#46;</p></span><span id="sec0135" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0155">Conflicts of Interest</span><p id="par0305" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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        4 => array:2 [
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          "titulo" => "Introduction"
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        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Lupus Erythematosus Panniculitis"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Pseudolymphoma in Tattoos"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Pseudolymphoma at the Site of Vaccination"
        ]
        8 => array:2 [
          "identificador" => "sec0025"
          "titulo" => "Lymphocytoma Cutis"
        ]
        9 => array:2 [
          "identificador" => "sec0030"
          "titulo" => "Pseudolymphoma in Acrodermatitis Chronica Atrophicans Lesions"
        ]
        10 => array:2 [
          "identificador" => "sec0035"
          "titulo" => "Pseudolymphomatous Folliculitis"
        ]
        11 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Lymphomatoid Drug Reaction"
        ]
        12 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Morphea"
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        13 => array:2 [
          "identificador" => "sec0050"
          "titulo" => "Acral Pseudolymphomatous Angiokeratoma&#47;Small Papular Pseudolymphoma"
        ]
        14 => array:2 [
          "identificador" => "sec0055"
          "titulo" => "T Cell&#8211;Rich Angiomatoid Polypoid Pseudolymphoma"
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        15 => array:2 [
          "identificador" => "sec0060"
          "titulo" => "Pretibial Lymphoplasmacytic Plaque in Children"
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        16 => array:2 [
          "identificador" => "sec0065"
          "titulo" => "Secondary Syphilis"
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        17 => array:2 [
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          "titulo" => "Persistent Arthropod Bite Reaction"
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        18 => array:2 [
          "identificador" => "sec0075"
          "titulo" => "Actinic Reticuloid"
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        19 => array:2 [
          "identificador" => "sec0080"
          "titulo" => "Lichen Sclerosus"
        ]
        20 => array:2 [
          "identificador" => "sec0085"
          "titulo" => "Lichen Aureus"
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        21 => array:2 [
          "identificador" => "sec0090"
          "titulo" => "Solitary T-Cell Pseudolymphoma"
        ]
        22 => array:2 [
          "identificador" => "sec0095"
          "titulo" => "Lichenoid Keratosis"
        ]
        23 => array:2 [
          "identificador" => "sec0100"
          "titulo" => "Lymphomatoid Contact Dermatitis"
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        24 => array:2 [
          "identificador" => "sec0105"
          "titulo" => "Atypical CD8 Lymphoid Proliferation in Patients With Human Immunodeficiency Virus"
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        25 => array:2 [
          "identificador" => "sec0110"
          "titulo" => "CD30 T-Cell Pseudolymphoma"
        ]
        26 => array:2 [
          "identificador" => "sec0115"
          "titulo" => "Immunoglobulin G4&#8211;Related Sclerosing Disease"
        ]
        27 => array:2 [
          "identificador" => "sec0120"
          "titulo" => "Annular Lichenoid Dermatitis"
        ]
        28 => array:2 [
          "identificador" => "sec0125"
          "titulo" => "Palpable Migratory Arciform Erythema"
        ]
        29 => array:2 [
          "identificador" => "sec0130"
          "titulo" => "Other Cutaneous Pseudolymphomas"
        ]
        30 => array:2 [
          "identificador" => "sec0135"
          "titulo" => "Conflicts of Interest"
        ]
        31 => array:2 [
          "identificador" => "xack277332"
          "titulo" => "Acknowledgments"
        ]
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          "titulo" => "References"
        ]
      ]
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    "fechaRecibido" => "2015-12-21"
    "fechaAceptado" => "2016-05-01"
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            0 => "Pseudolymphoma"
            1 => "Skin"
            2 => "Cutaneous lymphoid hyperplasia"
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          "palabras" => array:3 [
            0 => "Pseudolinfoma"
            1 => "Piel"
            2 => "Hiperplasia linfoide cut&#225;nea"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The term <span class="elsevierStyleItalic">cutaneous pseudolymphoma</span> refers to benign reactive lymphoid proliferations in the skin that simulate cutaneous lymphomas&#46; It is a purely descriptive term that encompasses various reactive conditions with a varied etiology&#44; pathogenesis&#44; clinical presentation&#44; histology&#44; and behavior&#46; We present a review of the different types of cutaneous pseudolymphoma&#46; To reach a correct diagnosis&#44; it is necessary to contrast clinical&#44; histologic&#44; immunophenotypic&#44; and molecular findings&#46; Even with these data&#44; in some cases only the clinical course will confirm the diagnosis&#44; making follow-up essential&#46;</p></span>"
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        "titulo" => "Resumen"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El t&#233;rmino pseudolinfoma cut&#225;neo designa proliferaciones linfoides cut&#225;neas benignas de naturaleza reactiva que simulan linfomas cut&#225;neos&#46; Se trata de un t&#233;rmino puramente descriptivo que engloba diferentes entidades reactivas&#44; con diversa etiolog&#237;a&#44; patog&#233;nesis&#44; presentaci&#243;n cl&#237;nica&#44; histolog&#237;a y comportamiento&#46; En el presente art&#237;culo revisaremos los distintos tipos de pseudolinfoma cut&#225;neo&#46; Como veremos&#44; para llegar al correcto diagn&#243;stico de los mismos ser&#225; preciso en cada caso la integraci&#243;n de los datos cl&#237;nicos con los histopatol&#243;gicos&#44; inmunofenot&#237;picos y moleculares&#46; Incluso entonces&#44; en ocasiones solo la evoluci&#243;n confirmar&#225; el diagn&#243;stico&#44; por lo que el seguimiento ser&#225; esencial&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Romero-P&#233;rez D&#44; Blanes Mart&#237;nez M&#44; Encabo-Dur&#225;n B&#46; Pseudolinfomas cut&#225;neos&#46; Actas Dermosifiliogr&#46; 2016&#59;107&#58;640&#8211;651&#46;</p>"
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          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Lymphoid follicles in the subcutaneous tissue separated by areas of fibrosis in this vaccination-induced pseudolymphoma &#40;hematoxylin-eosin&#44; original magnification &#215;<span class="elsevierStyleHsp" style=""></span>10&#41;&#46;</p>"
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          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Histiocytes with basophilic granular cytoplasm corresponding to the aluminum component of a vaccine&#44; intermixed with lymphocytes&#44; together with eosinophils and plasma cells &#40;hematoxylin-eosin&#44; original magnification &#215;<span class="elsevierStyleHsp" style=""></span>40&#41;&#46;</p>"
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          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Lymphocytoma cutis&#46; Solitary lesion on the back&#46;</p>"
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          "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Histologic image of the lymphocytoma cutis shown in <a class="elsevierStyleCrossRef" href="#fig0015">Figure 3</a>&#46; Dense mixed dermal infiltrate&#46; Note the merging germinal centers devoid of the mantel zone&#44; simulating a B-cell lymphoma &#40;hematoxylin-eosin&#44; original magnification &#215;<span class="elsevierStyleHsp" style=""></span>20&#41;&#46;</p>"
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          "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Lymphomatoid contact dermatitis&#46; In this patient sensitized to methylchloroisothiazolinone and colophony&#44; histology showed a band-like lymphocytic infiltrate and in some areas without spongiosis&#44; clusters in the epidermis reminiscent of Pautrier microabscesses&#46;</p>"
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                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lupus erythematosus panniculitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma in tattoos&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma at the site of vaccination&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphocytoma cutis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphoma in acrodermatitis chronica atrophicans lesions&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pseudolymphomatous folliculitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphomatoid drug reaction&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Morphea&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Acral pseudolymphomatous angiokeratoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">T cell&#8211;rich angiomatoid polypoid pseudolymphoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Pretibial lymphoplasmacytic plaque&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Secondary syphilis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Persistent arthropod bite reaction&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Actinic reticuloid&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichen sclerosus et atrophicus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichen aureus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Solitary T-cell pseudolymphoma&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lichenoid keratosis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Lymphomatoid contact dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Atypical lymphoid proliferation in patients with human immunodeficiency virus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">CD30<span class="elsevierStyleSup">&#43;</span> pseudolymphomas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Immunoglobulin G4-related disease&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Annular lichenoid dermatitis&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Palpable migratory arciform erythema&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Other cutaneous pseudolymphomas&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Cutaneous Pseudolymphoma&#46;</p>"
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          "leyenda" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Abbreviations&#58; ACE&#44; angiotensin-converting enzyme&#59; NSAIDs&#44; nonsteroidal anti-inflammatory drugs&#46;</p><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Source&#58; Ploysangam et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0900"><span class="elsevierStyleSup">36</span></a> Naciri Bennani et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0975"><span class="elsevierStyleSup">51</span></a> Imafuku et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0980"><span class="elsevierStyleSup">52</span></a> Fukamachi et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0985"><span class="elsevierStyleSup">53</span></a> Guis et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0990"><span class="elsevierStyleSup">54</span></a> Stavrianeas et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib0995"><span class="elsevierStyleSup">55</span></a> Welsh et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1000"><span class="elsevierStyleSup">56</span></a> Kitagawa et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1005"><span class="elsevierStyleSup">57</span></a> Macisaac et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1010"><span class="elsevierStyleSup">58</span></a> Kim et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1015"><span class="elsevierStyleSup">59</span></a> Foley et al&#46;<a class="elsevierStyleCrossRef" href="#bib1020"><span class="elsevierStyleSup">60</span></a></p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Anticonvulsants</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Phenytoin&#44; carbamazepine&#44; mephenytoin&#44; trimethadione&#44; phenobarbital&#44; primidone&#44; butabarbital&#44; methsuximide&#44; phensuximide&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Antipsychotics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Chlorpromazine&#44; thioridazine&#44; promethazine&#44; methylphenidate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Antihypertensives</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>ACE inhibitors&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Captopril&#44; enalapril&#44; benazepril&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>&#946;-Blockers&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Atenolol&#44; labetalol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Calcium channel blockers&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Verapamil&#44; diltiazem&#44; benidipine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Diuretics&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Moduretic&#44; hydrochlorothiazide&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Cytotoxic agents&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Ciclosporin&#44; methotrexate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Rheumatology drugs</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Gold&#44; salicylates&#44; phenacetin&#44; D-penicillamine&#44; allopurinol&#44; NSAIDs&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Antibiotics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Penicillin&#44; dapsone&#44; nitrofurantoin&#44; vancomycin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Antidepressants</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Fluoxetine&#44; doxepin&#44; depramine&#44; amitriptyline&#44; lithium&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Anxiolytics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Benzodiazepines &#40;clonazepam&#44; lorazepam&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Antihistamines</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Diphenhydramine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">H2 antihistamines</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Cimetidine&#44; ranitidine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Antiarrhythmics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Procainamide&#44; mexiletine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Topical agents</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Menthol&#44; eugenol&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Sex hormones</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Estrogens&#44; progesterone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Lipid-lowering drugs</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Lovastatin&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Biologics</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Adalimumab&#44; infliximab&#44; etanercept&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Other</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Lornoxicam&#44; zoledronic acid&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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        "descripcion" => array:1 [
          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Drugs Associated With Pseudolymphomatous Cutaneous Reactions&#46;</p>"
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        "tipo" => "MULTIMEDIATABLA"
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            "identificador" => "at3"
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          "leyenda" => "<p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Source&#58; Orbaneja et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1230"><span class="elsevierStyleSup">102</span></a> Marli&#232;re et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1245"><span class="elsevierStyleSup">105</span></a> Wall et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1250"><span class="elsevierStyleSup">106</span></a> Schena et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1255"><span class="elsevierStyleSup">107</span></a> Danese et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1260"><span class="elsevierStyleSup">108</span></a> Calzavara-Pinton et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1265"><span class="elsevierStyleSup">109</span></a> Fleming et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1270"><span class="elsevierStyleSup">110</span></a> Park et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1275"><span class="elsevierStyleSup">111</span></a> Komatsu et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1280"><span class="elsevierStyleSup">112</span></a> Pely et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1285"><span class="elsevierStyleSup">113</span></a> Millican et al&#46;&#44;<a class="elsevierStyleCrossRef" href="#bib1290"><span class="elsevierStyleSup">114</span></a> Mendese et al&#46;<a class="elsevierStyleCrossRef" href="#bib1295"><span class="elsevierStyleSup">115</span></a></p>"
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              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Phosphorus&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>N<span class="elsevierStyleItalic">-</span>Isopropyl<span class="elsevierStyleItalic">-</span>N<span class="elsevierStyleItalic">-</span>phenyl<span class="elsevierStyleItalic">-</span>4<span class="elsevierStyleItalic">-</span>phenylenediamine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Ethylenediamine dihydrochloride&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Napthen cobalt&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Nickel sulfate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Paraphenylenediamine&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Gold sodium thiosulfate&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Zinc&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Squaric acid dibutylester&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>Methylchloroisothiazolinone&#47;methylisothiazolinone&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
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          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Allergens Implicated in Lymphomatoid Contact Dermatitis&#46;</p>"
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              "identificador" => "bib0725"
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The lymphocytic infiltrates of the skin"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Hum Pathol"
                        "fecha" => "1974"
                        "volumen" => "5"
                        "paginaInicial" => "25"
                        "paginaFinal" => "43"
                        "link" => array:1 [ …1]
                      ]
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                  ]
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              "identificador" => "bib0730"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Histologic pseudomalignancies of the skin"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Dermatol"
                        "fecha" => "1976"
                        "volumen" => "112"
                        "paginaInicial" => "1767"
                        "paginaFinal" => "1780"
                        "link" => array:1 [ …1]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0735"
              "etiqueta" => "3"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous lymphomas and their histopathologic imitators"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Semin Dermatol"
                        "fecha" => "1986"
                        "volumen" => "5"
                        "paginaInicial" => "322"
                        "paginaFinal" => "333"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Inflammatory diseases that simulate lymphomas&#58; Cutaneous pseudolymphomas"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "LibroEditado" => array:5 [
                        "titulo" => "Dermatology in general medicine"
                        "paginaInicial" => "1315"
                        "paginaFinal" => "1327"
                        "edicion" => "4th ed"
                        "serieFecha" => "1993"
                      ]
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                  ]
                ]
              ]
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                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous lymphoid hyperplasia"
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                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
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                    0 => array:1 [
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                        "tituloSerie" => "Cancer"
                        "fecha" => "1969"
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                        "paginaInicial" => "487"
                        "paginaFinal" => "502"
                        "link" => array:1 [ …1]
                        "itemHostRev" => array:3 [ …3]
                      ]
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                  "contribucion" => array:1 [
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                      "titulo" => "Pseudolymphomas of the skin&#46; In&#58; An illustrated guide to skin lymphoma"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:6 [
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                        "fecha" => "2004"
                        "paginaInicial" => "155"
                        "paginaFinal" => "176"
                        "editorial" => "Blackwell Publishing Ltd"
                        "editorialLocalizacion" => "Oxford"
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Cutaneous MALT-lymphoma&#58; From cutaneous immunocytoma and pseudolymphoma to the current &#40;and future&#41; conceptions"
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                    0 => array:1 [
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Differential diagnosis of malignant and benign cutaneous lymphoid infiltrates&#58; A study of 57 cases in which malignant lymphoma had been diagnosed or suspected in the skin"
                      "autores" => array:1 [
                        0 => array:2 [ …2]
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                    ]
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                  "host" => array:1 [
                    0 => array:1 [
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                        "tituloSerie" => "Cancer"
                        "fecha" => "1979"
                        "volumen" => "44"
                        "paginaInicial" => "699"
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              ]
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              "identificador" => "bib0765"
              "etiqueta" => "9"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunohistochemical classification of cutaneous pseudolymphomas&#58; Delineation of distinct patterns"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
                ]
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                    0 => array:2 [
                      "titulo" => "Two cases of bilateral earlobe cutaneous pseudolymphoma"
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                    0 => array:2 [
                      "doi" => "10.1111/bjd.13145"
                      "Revista" => array:7 [ …7]
                    ]
                  ]
                ]
              ]
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                0 => array:2 [
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                      "titulo" => "Cutaneous pseudolymphomas&#58; Inflammatory reactive proliferations"
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                    0 => array:2 [
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                      "Revista" => array:6 [ …6]
                    ]
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              "identificador" => "bib0780"
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                    0 => array:2 [
                      "titulo" => "Pseudolymphoma and cutaneous lymphoma&#58; Facts and controversies"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clindermatol.2010.04.005"
                      "Revista" => array:6 [ …6]
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                  ]
                ]
              ]
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              "identificador" => "bib0785"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mycosis fungoides--a disease of antigen persistence"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
                ]
              ]
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              "identificador" => "bib0790"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is mycosis fungoides an immunoma&#63;"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
                ]
              ]
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              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Evolution of B-cell lymphoma from pseudolymphoma&#46; A multidisciplinary approach using histology&#44; immunohistochemistry&#44; and southern blot analysis"
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                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                    0 => array:2 [
                      "titulo" => "Cutaneous lymphoid hyperplasia and marginal zone B-cell lymphoma following vaccination"
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                    ]
                  ]
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                    0 => array:2 [
                      "doi" => "10.1016/j.jaad.2005.04.036"
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                    ]
                  ]
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              ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Lymphomatoid contact dermatitis caused by nickel"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0810"
              "etiqueta" => "18"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Idiopathic cutaneous pseudolymphoma&#58; An enigma"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.4103/2229-5178.131143"
                      "Revista" => array:6 [ …6]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0815"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous pseudolymphoma&#58; A case report with an immunohistochemical study"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
                ]
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Diagnostic immunohistology&#58; Cutaneous lymphomas and pseudolymphomas"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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              "etiqueta" => "21"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Differential diagnosis between cutaneous lymphoma and pseudolymphoma"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
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              "identificador" => "bib0830"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Differential diagnosis of cutaneous infiltrates of B lymphocytes with follicular growth pattern"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                  ]
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "T-cell receptor and immunoglobulin gene rearrangements in diagnosing skin disease"
                      "autores" => array:1 [ …1]
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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              "etiqueta" => "24"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Immunophenotyping and gene rearrangement analysis provide additional criteria to differentiate between cutaneous T-cell lymphomas and pseudo-T-cell lymphomas"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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              "etiqueta" => "25"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous lymphoid hyperplasia&#46; Immunologic characteristics and assessment of criteria recently proposed as diagnostic of malignant lymphoma"
                      "autores" => array:1 [ …1]
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                  ]
                  "host" => array:1 [
                    0 => array:1 [
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                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Demonstration of clonal immunoglobulin gene rearrangements in cutaneous B-cell lymphomas and pseudo-B-cell lymphomas&#58; Differential diagnostic and pathogenetic aspects"
                      "autores" => array:1 [ …1]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [ …7]
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                0 => array:2 [
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                      "autores" => array:1 [ …1]
                    ]
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                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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              ]
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                0 => array:2 [
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                      "titulo" => "Lymphomatoid drug reaction secondary to methylphenidate hydrochloride"
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                    0 => array:1 [
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                    0 => array:1 [
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                      "titulo" => "Pathologic findings in human scabies"
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                    0 => array:1 [
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                    0 => array:1 [
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                    0 => array:1 [
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                    0 => array:1 [
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                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                      "titulo" => "Lichen sclerosus with histopathologic features simulating early mycosis fungoides"
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                    0 => array:1 [
                      "Revista" => array:7 [ …7]
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                    0 => array:1 [
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                    0 => array:2 [
                      "titulo" => "A proposed new classification system for lichenoid keratosis"
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                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                    0 => array:1 [
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                    0 => array:1 [
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                    0 => array:1 [
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                    0 => array:1 [
                      "Revista" => array:7 [ …7]
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                    0 => array:1 [
                      "Revista" => array:6 [ …6]
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                      "titulo" => "Cutaneous pseudolymphoma in association with molluscum contagiosum in an elderly patient"
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Article information

ISSN: 15782190
Original language: English

DOI:10.1016/j.adengl.2016.07.011

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