Original article
Current Prevalence and Characteristics of Dermatoses Associated with Human Immunodeficiency Virus Infection
Prevalencia y características de las dermatosis relacionadas con la infección por VIH en la actualidad
M. Blanesa,
, I. Belinchónb, E. Merinoc, J. Portillac, J. Sánchez-Payád, I. Betllochb
Corresponding author
a Unidad de Dermatología, Hospital Marina Baixa, Villajoyosa, Alicante, Spain
b Sección de Dermatología, Hospital General Universitario de Alicante, Alicante, Spain
c Unidad de Enfermedades Infecciosas, Hospital General Universitario de Alicante, Alicante, Spain
d Servicio de Medicina Preventiva, Hospital General Universitario de Alicante, Alicante, Spain
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"apellidos" => "Blanes" "email" => array:1 [ 0 => "blanes_marmar@gva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "I." "apellidos" => "Belinchón" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "E." "apellidos" => "Merino" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "J." "apellidos" => "Portilla" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "J." 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The frequency of opportunistic infections and AIDS-related cancers has fallen, though new health problems have developed. Likewise, there has been a change in the spectrum of skin diseases now observed in these patients.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To analyze the prevalence and characteristics of skin disease in a group of HIVinfected outpatients.</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">A cross-sectional, observational study was performed. All patients who attended the day care unit of the infectious diseases department over a 6-month period (May-October, 2003) were offered the possibility of complete dermatologic examination. Epidemiologic and clinical variables were recorded in all participants, together with the findings on examination of the skin. A comparative study was performed, grouping the patients according to CD4-lymphocyte count and antiretroviral treatment.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The prevalence of dermatoses in the study patients was 98.3%. The most common conditions were xerosis (114 patients, 37.6%), seborrheic dermatitis (94 patients, 31%), distal subungual onychomycosis (80 patients, 26.4%), and viral warts (65 patients, 21.4%). Grouped by etiology, infectious diseases were the most common (68.6%), followed by inflammatory diseases (47.5%).</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Mucocutaneous lesions continue to be very common in HIV-infected patients, although there has been a qualitative change in the conditions that these patients present.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La introducción del tratamiento antirretroviral de gran actividad (TARGA) ha supuesto un cambio profundo en la historia natural de la infección por VIH. Las infecciones oportunistas y las neoplasias asociadas a sida han visto reducida su frecuencia, a la vez que han dado paso a nuevos problemas de salud. De igual manera, el espectro de la patología cutánea que actualmente observamos en estos pacientes se ha visto modificado.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Analizar la prevalencia y características de la patología cutánea en una serie de pacientes ambulatorios con infección por VIH.</p> <span class="elsevierStyleSectionTitle">Métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudio transversal, observacional. A todos los pacientes que acudieron al Hospital de Día de la Unidad de Enfermedades Infecciosas durante un periodo de seis meses (mayo-octubre 2003) se les ofreció la posibilidad de la realización de un examen dermatológico completo. Se registraron las variables epidemiológicas y clínicas de todos los participantes y los hallazgos de la exploración cutánea. Los pacientes fueron estudiados comparativamente según su recuento de linfocitos CD4 y si realizaban o no tratamiento antirretroviral.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">La frecuencia de dermatosis en los pacientes del estudio fue del 98,3%. Las entidades más frecuentes fueron: xerosis (114 pacientes, 37,6%); dermatitis seborreica (94 pacientes, 31%); onicomicosis subungueal distal (80 pacientes, 26,4%) y verrugas vulgares (65 pacientes, 21,4%). Agrupadas por categorías, la patología infecciosa fue la más frecuente (68,6%), seguida de la patología inflamatoria (47,5%).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Las lesiones cutáneo-mucosas continúan siendo muy frecuentes en los pacientes con infección por VIH, aunque se ha producido un cambio cualitativo en la patología que presentan.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:18 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Panel de expertos de Gesida y Plan Nacional sobre el Sida. Recomendaciones de Gesida/Plan Nacional sobre el Sida respecto al tratamiento antirretroviral en adultos infectados por el virus de la inmunodeficiencia humana (Actualización febrero 2009). GESIDA. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 10 | 15 | 25 |
| 2024 October | 52 | 35 | 87 |
| 2024 September | 53 | 24 | 77 |
| 2024 August | 79 | 76 | 155 |
| 2024 July | 57 | 35 | 92 |
| 2024 June | 61 | 29 | 90 |
| 2024 May | 47 | 32 | 79 |
| 2024 April | 55 | 25 | 80 |
| 2024 March | 49 | 35 | 84 |
| 2024 February | 41 | 45 | 86 |
| 2024 January | 45 | 38 | 83 |
| 2023 December | 46 | 21 | 67 |
| 2023 November | 40 | 34 | 74 |
| 2023 October | 42 | 41 | 83 |
| 2023 September | 45 | 42 | 87 |
| 2023 August | 36 | 21 | 57 |
| 2023 July | 33 | 68 | 101 |
| 2023 June | 35 | 20 | 55 |
| 2023 May | 39 | 34 | 73 |
| 2023 April | 22 | 25 | 47 |
| 2023 March | 17 | 21 | 38 |
| 2023 February | 23 | 18 | 41 |
| 2023 January | 18 | 37 | 55 |
| 2022 December | 25 | 36 | 61 |
| 2022 November | 12 | 28 | 40 |
| 2022 October | 16 | 13 | 29 |
| 2022 September | 18 | 40 | 58 |
| 2022 August | 16 | 27 | 43 |
| 2022 July | 11 | 43 | 54 |
| 2022 June | 12 | 24 | 36 |
| 2022 May | 22 | 34 | 56 |
| 2022 April | 20 | 41 | 61 |
| 2022 March | 23 | 56 | 79 |
| 2022 February | 15 | 21 | 36 |
| 2022 January | 14 | 40 | 54 |
| 2021 December | 16 | 41 | 57 |
| 2021 November | 22 | 43 | 65 |
| 2021 October | 23 | 48 | 71 |
| 2021 September | 23 | 51 | 74 |
| 2021 August | 9 | 25 | 34 |
| 2021 July | 19 | 36 | 55 |
| 2021 June | 14 | 26 | 40 |
| 2021 May | 20 | 42 | 62 |
| 2021 April | 31 | 64 | 95 |
| 2021 March | 56 | 21 | 77 |
| 2021 February | 52 | 25 | 77 |
| 2021 January | 24 | 25 | 49 |
| 2020 December | 16 | 16 | 32 |
| 2020 November | 34 | 24 | 58 |
| 2020 October | 24 | 12 | 36 |
| 2020 September | 21 | 14 | 35 |
| 2020 August | 27 | 29 | 56 |
| 2020 July | 11 | 11 | 22 |
| 2020 June | 21 | 23 | 44 |
| 2020 May | 26 | 20 | 46 |
| 2020 April | 30 | 24 | 54 |
| 2020 March | 20 | 23 | 43 |
| 2020 February | 3 | 3 | 6 |
| 2020 January | 0 | 5 | 5 |
| 2019 December | 0 | 13 | 13 |
| 2019 November | 0 | 2 | 2 |
| 2019 September | 0 | 5 | 5 |
| 2019 August | 0 | 3 | 3 |
| 2019 July | 0 | 10 | 10 |
| 2019 June | 0 | 1 | 1 |
| 2019 May | 0 | 34 | 34 |
| 2019 April | 0 | 1 | 1 |
| 2019 March | 0 | 2 | 2 |
| 2019 February | 0 | 4 | 4 |
| 2018 May | 0 | 2 | 2 |
| 2018 April | 0 | 5 | 5 |
| 2018 March | 0 | 3 | 3 |
| 2018 February | 11 | 1 | 12 |
| 2018 January | 19 | 8 | 27 |
| 2017 December | 19 | 8 | 27 |
| 2017 November | 16 | 4 | 20 |
| 2017 October | 16 | 7 | 23 |
| 2017 September | 21 | 9 | 30 |
| 2017 August | 37 | 5 | 42 |
| 2017 July | 25 | 8 | 33 |
| 2017 June | 20 | 33 | 53 |
| 2017 May | 16 | 9 | 25 |
| 2017 April | 20 | 5 | 25 |
| 2017 March | 15 | 35 | 50 |
| 2017 February | 26 | 13 | 39 |
| 2017 January | 16 | 4 | 20 |
| 2016 December | 39 | 6 | 45 |
| 2016 November | 29 | 4 | 33 |
| 2016 October | 24 | 16 | 40 |
| 2016 September | 19 | 1 | 20 |
| 2016 August | 25 | 6 | 31 |
| 2016 July | 23 | 7 | 30 |
| 2016 June | 8 | 16 | 24 |
| 2016 May | 8 | 3 | 11 |
| 2016 April | 2 | 10 | 12 |
| 2016 March | 5 | 1 | 6 |
| 2016 February | 12 | 1 | 13 |
| 2016 January | 6 | 2 | 8 |
| 2015 December | 11 | 0 | 11 |
| 2015 November | 15 | 1 | 16 |
| 2015 October | 4 | 3 | 7 |
| 2015 September | 6 | 1 | 7 |
| 2015 August | 10 | 2 | 12 |
| 2015 July | 27 | 13 | 40 |
| 2015 June | 17 | 9 | 26 |
| 2015 May | 59 | 11 | 70 |
| 2015 April | 35 | 5 | 40 |
| 2015 March | 30 | 9 | 39 |
| 2015 February | 17 | 6 | 23 |
| 2015 January | 25 | 11 | 36 |
| 2014 December | 40 | 6 | 46 |
| 2014 November | 20 | 11 | 31 |
| 2014 October | 33 | 15 | 48 |
| 2014 September | 25 | 19 | 44 |
| 2014 August | 25 | 18 | 43 |
| 2014 July | 27 | 19 | 46 |
| 2014 June | 37 | 11 | 48 |
| 2014 May | 27 | 10 | 37 |
| 2014 April | 36 | 11 | 47 |
| 2014 March | 47 | 21 | 68 |
| 2014 February | 29 | 9 | 38 |
| 2014 January | 29 | 13 | 42 |
| 2013 December | 28 | 16 | 44 |
| 2013 November | 33 | 19 | 52 |
| 2013 October | 35 | 18 | 53 |
| 2013 September | 23 | 17 | 40 |
| 2013 August | 24 | 21 | 45 |
| 2013 July | 38 | 33 | 71 |
| 2013 June | 29 | 30 | 59 |
| 2013 May | 19 | 13 | 32 |
| 2013 April | 20 | 24 | 44 |
| 2013 March | 22 | 25 | 47 |
| 2013 February | 15 | 18 | 33 |
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