Controversies in dermatology
Surgical vs Nonsurgical Treatment of Basal Cell Carcinoma
Tratamiento quirúrgico vs. no quirúrgico en el carcinoma basocelular
I.R. Aguayo-Leiva
, L. Ríos-Buceta, P. Jaén-Olasolo
Corresponding author
Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Cepeda-Valdés, G. Pohla-Gubo, J.R. Borbolla-Escoboza, O. Barboza-Quintana, J. Ancer-Rodríguez, H. Hintner, J.C. Salas-Alanisa" "autores" => array:7 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Cepeda-Valdés" ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Pohla-Gubo" ] 2 => array:2 [ "nombre" => "J.R." "apellidos" => "Borbolla-Escoboza" ] 3 => array:2 [ "nombre" => "O." "apellidos" => "Barboza-Quintana" ] 4 => array:2 [ "nombre" => "J." "apellidos" => "Ancer-Rodríguez" ] 5 => array:2 [ "nombre" => "H." "apellidos" => "Hintner" ] 6 => array:2 [ "nombre" => "J.C." "apellidos" => "Salas-Alanisa" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219010706971?idApp=UINPBA000044" "url" => "/15782190/0000010100000008/v1_201304241529/S1578219010706971/v1_201304241529/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Controversies in dermatology</span>" "titulo" => "Surgical vs Nonsurgical Treatment of Basal Cell Carcinoma" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "683" "paginaFinal" => "692" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "I.R. Aguayo-Leiva, L. Ríos-Buceta, P. Jaén-Olasolo" "autores" => array:3 [ 0 => array:4 [ "nombre" => "I.R." "apellidos" => "Aguayo-Leiva" "email" => array:1 [ 0 => "ingridaguayo77@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Ríos-Buceta" ] 2 => array:2 [ "nombre" => "P." "apellidos" => "Jaén-Olasolo" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Tratamiento quirúrgico vs. no quirúrgico en el carcinoma basocelular" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2010-02-13" "fechaAceptado" => "2010-06-22" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec84791" "palabras" => array:5 [ 0 => "Carcinoma" 1 => "Basal cell" 2 => "Skin cancer" 3 => "Treatment" 4 => "Surgery" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84790" "palabras" => array:5 [ 0 => "Carcinoma" 1 => "Basocelular" 2 => "Cáncer de piel" 3 => "Tratamiento" 4 => "Cirugía" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Numerous therapeutic options are now available for the treatment of basal cell carcinoma. However, few randomized controlled trials with 5-year follow-up have compared the effectiveness of the different treatments. Such a comparison is difficult, probably because efficacy depends on several factors: those related to the tumor, the patient, the technique, and the dermatologist's experience. We first describe the available therapeutic options, including certain innovative treatments. We have divided them into 2 main groups—surgical and nonsurgical—and focus on the indications, advantages, and disadvantages of each one, as well as on the cure and recurrence rates. Then, based on the evidence reviewed, we attempt to provide an outline of the therapeutic strategies recommended in basal cell carcinoma, and the approach to be used in specific situations. We also describe our own experience.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El arsenal terapéutico para el tratamiento de los carcinomas basocelulares hoy en día es muy amplio. No obstante, existen pocos estudios controlados, aleatorizados con seguimiento a 5 años que comparen la eficacia de los diferentes tratamientos. Esto es difícil, debido probablemente a que la eficacia de los mismos depende de varios factores: los derivados del propio tumor, del paciente, de la técnica y del manejo de ella hecho por el dermatólogo. Describiremos en primer lugar las opciones terapéuticas con las que contamos, incluyendo además algunos tratamientos innovadores, dividiéndolas en dos grupos principales: quirúrgicos y no quirúrgicos, enfatizando en las indicaciones, ventajas y desventajas de cada tipo, así como las tasas de curación y recurrencia de los mismos. Posteriormente con las evidencias presentadas intentaremos, de manera esquemática, exponer las estrategias terapéuticas recomendadas en cada caso, las actitudes a adoptar en determinadas situaciones así como nuestra propia experiencia.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:54 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Cancer statistics 2008" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Jemal" 1 => "R. Siegel" 2 => "E. Ward" 3 => "Y. Hao" 4 => "J. Xu" 5 => "T. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 16 | 22 |
| 2024 October | 73 | 52 | 125 |
| 2024 September | 61 | 53 | 114 |
| 2024 August | 86 | 86 | 172 |
| 2024 July | 65 | 52 | 117 |
| 2024 June | 70 | 35 | 105 |
| 2024 May | 65 | 46 | 111 |
| 2024 April | 63 | 32 | 95 |
| 2024 March | 57 | 38 | 95 |
| 2024 February | 76 | 38 | 114 |
| 2024 January | 51 | 37 | 88 |
| 2023 December | 71 | 30 | 101 |
| 2023 November | 73 | 42 | 115 |
| 2023 October | 70 | 76 | 146 |
| 2023 September | 53 | 54 | 107 |
| 2023 August | 46 | 28 | 74 |
| 2023 July | 62 | 83 | 145 |
| 2023 June | 43 | 45 | 88 |
| 2023 May | 41 | 67 | 108 |
| 2023 April | 32 | 52 | 84 |
| 2023 March | 38 | 29 | 67 |
| 2023 February | 27 | 21 | 48 |
| 2023 January | 33 | 42 | 75 |
| 2022 December | 31 | 40 | 71 |
| 2022 November | 19 | 31 | 50 |
| 2022 October | 19 | 21 | 40 |
| 2022 September | 17 | 38 | 55 |
| 2022 August | 21 | 29 | 50 |
| 2022 July | 13 | 29 | 42 |
| 2022 June | 17 | 27 | 44 |
| 2022 May | 26 | 36 | 62 |
| 2022 April | 53 | 41 | 94 |
| 2022 March | 29 | 58 | 87 |
| 2022 February | 14 | 30 | 44 |
| 2022 January | 47 | 47 | 94 |
| 2021 December | 23 | 39 | 62 |
| 2021 November | 24 | 51 | 75 |
| 2021 October | 31 | 54 | 85 |
| 2021 September | 25 | 47 | 72 |
| 2021 August | 25 | 62 | 87 |
| 2021 July | 29 | 40 | 69 |
| 2021 June | 29 | 36 | 65 |
| 2021 May | 28 | 40 | 68 |
| 2021 April | 48 | 40 | 88 |
| 2021 March | 48 | 28 | 76 |
| 2021 February | 39 | 29 | 68 |
| 2021 January | 40 | 13 | 53 |
| 2020 December | 40 | 23 | 63 |
| 2020 November | 32 | 22 | 54 |
| 2020 October | 29 | 9 | 38 |
| 2020 September | 43 | 13 | 56 |
| 2020 August | 35 | 32 | 67 |
| 2020 July | 29 | 9 | 38 |
| 2020 June | 33 | 35 | 68 |
| 2020 May | 27 | 31 | 58 |
| 2020 April | 26 | 22 | 48 |
| 2020 March | 34 | 31 | 65 |
| 2020 February | 4 | 2 | 6 |
| 2020 January | 0 | 5 | 5 |
| 2019 December | 0 | 9 | 9 |
| 2019 November | 0 | 7 | 7 |
| 2019 October | 0 | 3 | 3 |
| 2019 September | 0 | 6 | 6 |
| 2019 August | 0 | 4 | 4 |
| 2019 July | 0 | 1 | 1 |
| 2019 June | 0 | 6 | 6 |
| 2019 May | 0 | 38 | 38 |
| 2019 April | 1 | 1 | 2 |
| 2019 March | 0 | 7 | 7 |
| 2019 February | 0 | 2 | 2 |
| 2019 January | 0 | 1 | 1 |
| 2018 May | 0 | 1 | 1 |
| 2018 April | 0 | 12 | 12 |
| 2018 February | 11 | 4 | 15 |
| 2018 January | 17 | 5 | 22 |
| 2017 December | 15 | 9 | 24 |
| 2017 November | 11 | 3 | 14 |
| 2017 October | 12 | 12 | 24 |
| 2017 September | 17 | 4 | 21 |
| 2017 August | 31 | 5 | 36 |
| 2017 July | 32 | 6 | 38 |
| 2017 June | 32 | 24 | 56 |
| 2017 May | 30 | 10 | 40 |
| 2017 April | 38 | 19 | 57 |
| 2017 March | 32 | 15 | 47 |
| 2017 February | 18 | 14 | 32 |
| 2017 January | 21 | 6 | 27 |
| 2016 December | 28 | 7 | 35 |
| 2016 November | 27 | 10 | 37 |
| 2016 October | 25 | 13 | 38 |
| 2016 September | 26 | 10 | 36 |
| 2016 August | 35 | 14 | 49 |
| 2016 July | 21 | 6 | 27 |
| 2016 June | 13 | 10 | 23 |
| 2016 May | 5 | 13 | 18 |
| 2016 April | 6 | 27 | 33 |
| 2016 March | 3 | 16 | 19 |
| 2016 February | 9 | 19 | 28 |
| 2016 January | 7 | 18 | 25 |
| 2015 December | 6 | 1 | 7 |
| 2015 November | 6 | 16 | 22 |
| 2015 October | 9 | 18 | 27 |
| 2015 September | 4 | 11 | 15 |
| 2015 August | 10 | 3 | 13 |
| 2015 July | 25 | 13 | 38 |
| 2015 June | 30 | 10 | 40 |
| 2015 May | 57 | 16 | 73 |
| 2015 April | 35 | 20 | 55 |
| 2015 March | 33 | 26 | 59 |
| 2015 February | 30 | 11 | 41 |
| 2015 January | 25 | 18 | 43 |
| 2014 December | 46 | 15 | 61 |
| 2014 November | 44 | 14 | 58 |
| 2014 October | 32 | 28 | 60 |
| 2014 September | 38 | 21 | 59 |
| 2014 August | 34 | 20 | 54 |
| 2014 July | 60 | 18 | 78 |
| 2014 June | 46 | 16 | 62 |
| 2014 May | 48 | 21 | 69 |
| 2014 April | 45 | 17 | 62 |
| 2014 March | 42 | 19 | 61 |
| 2014 February | 37 | 18 | 55 |
| 2014 January | 37 | 24 | 61 |
| 2013 December | 33 | 22 | 55 |
| 2013 November | 26 | 16 | 42 |
| 2013 October | 37 | 21 | 58 |
| 2013 September | 33 | 25 | 58 |
| 2013 August | 32 | 18 | 50 |
| 2013 July | 31 | 31 | 62 |
| 2013 June | 24 | 42 | 66 |
| 2013 May | 22 | 21 | 43 |
| 2013 April | 21 | 37 | 58 |
| 2013 March | 34 | 37 | 71 |
| 2013 February | 18 | 19 | 37 |
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