Correspondence: Servicio de Dermatología, Hospital Clínico Universitario, Avda. Blasco Ibáñez 17, 46010 Valencia, Spain.
was read the article
array:23 [ "pii" => "S157821900970006X" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70006-X" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "70006" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "copyrightAnyo" => "2009" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2009;100:22-32" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3587 "formatos" => array:3 [ "EPUB" => 35 "HTML" => 2320 "PDF" => 1232 ] ] "itemSiguiente" => array:18 [ "pii" => "S1578219009700071" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70007-1" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "70007" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2009;100:33-7" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 3262 "formatos" => array:3 [ "EPUB" => 41 "HTML" => 1739 "PDF" => 1482 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Practical dermatology</span>" "titulo" => "Management of Acne in Women Over 25 Years of Age" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "33" "paginaFinal" => "37" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Manejo del Acné en Mujeres Mayores de 25 Años" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Rivera, A. Guerra" "autores" => array:2 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Rivera" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Guerra" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700071?idApp=UINPBA000044" "url" => "/15782190/0000010000000001/v1_201304241446/S1578219009700071/v1_201304241446/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S1578219009700058" "issn" => "15782190" "doi" => "10.1016/S1578-2190(09)70005-8" "estado" => "S300" "fechaPublicacion" => "2009-01-01" "aid" => "70005" "copyright" => "Academia Española de Dermatología y Venereología and Elsevier España, S.L." "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Dermosifiliogr. 2009;100:17-21" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 2307 "formatos" => array:3 [ "EPUB" => 33 "HTML" => 1405 "PDF" => 869 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Actas 1909-2009</span>" "titulo" => "Actas Dermo-Sifiliográficas, Volume 1, Number 1" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "17" "paginaFinal" => "21" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Actas Dermo-Sifiliográficas,Año 1, Número 1" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. del Río" "autores" => array:1 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "del Río" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1578219009700058?idApp=UINPBA000044" "url" => "/15782190/0000010000000001/v1_201304241446/S1578219009700058/v1_201304241446/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Advances in dermatology</span>" "titulo" => "Update on the Treatment of Genital Herpes" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "22" "paginaFinal" => "32" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.M. Martín, G. Villalón, E. Jordá" "autores" => array:3 [ 0 => array:4 [ "nombre" => "J.M." "apellidos" => "Martín" "email" => array:1 [ 0 => "jmmart@eresmas.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor1" ] ] ] 1 => array:2 [ "nombre" => "G." "apellidos" => "Villalón" ] 2 => array:2 [ "nombre" => "E." "apellidos" => "Jordá" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario, Valencia, Spain" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor1" "etiqueta" => "⁎" "correspondencia" => "Correspondence: Servicio de Dermatología, Hospital Clínico Universitario, Avda. Blasco Ibáñez 17, 46010 Valencia, Spain." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Actualización en el Tratamiento del Herpes Genital" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaAceptado" => "2008-04-21" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec84376" "palabras" => array:4 [ 0 => "genital herpes" 1 => "sexually transmitted disease" 2 => "aciclovir" 3 => "valac" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec84375" "palabras" => array:5 [ 0 => "herpes genital" 1 => "enfermedades de transmisión sexual" 2 => "aciclovir" 3 => "valaciclovir" 4 => "famciclovir" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">Genital herpes is a chronic infection characterized by periodic reactivation. It can produce symptomatic disease in the host although asymptomatic viral excretion can also occur. It is currently the main cause of genital ulceration and an important public health problem that has substantial clinical, psychological, and economic repercussions. This review analyzes the currently available therapeutic options and regimens, which are based mainly on systemic use of antiviral agents such as aciclovir, valacyclovir, and famciclovir. In addition, special emphasis is placed on the prevention and management of this infection in specific situations, such as pregnant, pediatric, and immunocompromised patients.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">El herpes genital es una infección crónica que se caracteriza por una reactivación periódica, con capacidad tanto de producir una enfermedad sintomática en el huésped como de excreción viral asintomática. Hoy en día constituye la primera causa de ulceración genital y representa un importante problema de salud pública, con considerables repercusiones clínicas, psicológicas y económicas.</p><p class="elsevierStyleSimplePara elsevierViewall">Se revisan y actualizan las distintas opciones y pautas terapéuticas disponibles en la actualidad, basadas fundamentalmente en el empleo por vía sistémica de los fármacos antivirales aciclovir, valaciclovir y famciclovir. Por otro lado, se pone especial énfasis en la prevención y el manejo de esta infección en situaciones particulares, como en embarazadas, en niños, o en pacientes inmunodeprimidos.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:81 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relation between herpes simplex viruses and human immunodeficiency virus infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "J.L. Severson" 1 => "S.K. Tyring" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "1999" "volumen" => "135" "paginaInicial" => "1393" "paginaFinal" => "1397" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10566840" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Herpes genital" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B. Milpied" 1 => "M. Javier" 2 => "C.H. Derancourt" 3 => "J.L. Verret" 4 => "E. Caumes" 5 => "F. Bouscarat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann Dermatol Venereol" "fecha" => "2006" "volumen" => "133" "paginaInicial" => "S28" "paginaFinal" => "S30" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Herpes simplex virus type 2 in the United States, 1976-1994" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D.T. Fleming" 1 => "G.M. McQuillan" 2 => "R.E. Johnson" 3 => "A.J. Nahmias" 4 => "S.O. Aral" 5 => "F.K. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199710163371601" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1997" "volumen" => "337" "paginaInicial" => "1105" "paginaFinal" => "1111" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9329932" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actualización del herpes genital. Epidemiología del herpes genital" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Velasco" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:3 [ "titulo" => "XIII Reunión del Grupo Español para la Investigación de las Enfermedades de Transmisión Sexual" "conferencia" => "Valencia" "serieFecha" => "2007" ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for the sexual transmission of genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G.J. Mertz" 1 => "J. Benedetti" 2 => "R. Ashley" 3 => "S.A. Selke" 4 => "L. Corey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1992" "volumen" => "116" "paginaInicial" => "197" "paginaFinal" => "202" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1309413" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tratamiento del herpes zóster" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M. Ferrán" 1 => "R.M. Pujol" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2006" "volumen" => "97" "numero" => "Supl 3" "paginaInicial" => "25" "paginaFinal" => "37" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Actualización en el tratamiento del herpes zóster" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. España" 1 => "P. Redondo" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2006" "volumen" => "97" "paginaInicial" => "103" "paginaFinal" => "114" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16595111" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oral acyclovir in acute herpes zoster" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.W. McKendrick" 1 => "J.I. McGill" 2 => "J.E. White" 3 => "M.J. Wood" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Br Med J" "fecha" => "1986" "volumen" => "293" "paginaInicial" => "1529" "paginaFinal" => "1532" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Valaciclovir compared with acyclovir for improved therapy for herpes zoster in immunocompetent adults" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K.R. Beutner" 1 => "D.J. Friedman" 2 => "C. Forszpaniak" 3 => "P.L. Andersen" 4 => "M.J. Wood" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Antimicrobiol Agents Chemother" "fecha" => "1995" "volumen" => "39" "paginaInicial" => "1546" "paginaFinal" => "1553" "itemHostRev" => array:3 [ "pii" => "S1552526010000634" "estado" => "S300" "issn" => "15525260" ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Valaciclovir: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in herpesvirus infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "C.M. Perry" 1 => "D. Faulds" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drugs" "fecha" => "1996" "volumen" => "52" "paginaInicial" => "754" "paginaFinal" => "772" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9118821" "web" => "Medline" ] ] ] ] ] ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mode of antiviral action of penciclovir in MRC-5 cells infected with herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "D.L. Earnshaw" 1 => "T.H. Bacon" 2 => "S.J. Darlison" 3 => "K. Edmonds" 4 => "R.M. Perkins" 5 => "RA. Vere Hodge" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Antimicrob Agents Chemother" "fecha" => "1992" "volumen" => "36" "paginaInicial" => "2747" "paginaFinal" => "2757" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1336346" "web" => "Medline" ] ] ] ] ] ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sexually transmitted diseases treatment guidelines, 2006" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Centers for Disease Control and Prevention" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "MMWR" "fecha" => "2006" "volumen" => "55" "paginaInicial" => "16" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16645577" "web" => "Medline" ] ] ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Herpes genital: review of the epidemic and potential use of type-specific serology" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.L. Ashley" 1 => "A. Wald" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Clin Microbiol Rev" "fecha" => "1999" "volumen" => "12" "paginaInicial" => "1" "paginaFinal" => "8" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9880471" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Single-day therapy: an expert opinion on a recent development for the episodic treatment of recurrent genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Tyring" 1 => "G. Richwald" 2 => "K. Hamed" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00404-007-0769-7" "Revista" => array:6 [ "tituloSerie" => "Arch Gynecol Obstet" "fecha" => "2007" "volumen" => "275" "paginaInicial" => "1" "paginaFinal" => "3" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17628818" "web" => "Medline" ] ] ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Once-daily valacyclovir to reduce the risk of transmission of genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Corey" 1 => "A. Wald" 2 => "R. Patel" 3 => "S.L. Sacks" 4 => "S.K. Tyring" 5 => "T. Warren" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMoa035144" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2004" "volumen" => "350" "paginaInicial" => "11" "paginaFinal" => "20" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14702423" "web" => "Medline" ] ] ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Effect of valacyclovir on viral shedding in immunocompetent patients with recurrent herpes simplex virus 2 genital herpes: a US-based randomized, double-blind, placebo-controlled clinical trial" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.H. Fife" 1 => "T.J. Warren" 2 => "R.D. Ferrera" 3 => "D.C. Young" 4 => "S.E. Justus" 5 => "C.K. Heitman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.4065/81.10.1321" "Revista" => array:7 [ "tituloSerie" => "Mayo Clin Proc" "fecha" => "2006" "volumen" => "81" "paginaInicial" => "1321" "paginaFinal" => "1327" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17036557" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1474442207701783" "estado" => "S300" "issn" => "14744422" ] ] ] ] ] ] ] 16 => array:3 [ "identificador" => "bib17" "etiqueta" => "17." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Comparative efficacy of famciclovir and valacyclovir for suppression of recurrent genital herpes and virus shedding" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Wald" 1 => "S. Selke" 2 => "T. Warren" 3 => "F.Y. Aoki" 4 => "S. Sacks" 5 => "F. Díaz-Mitoma" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.olq.0000204723.15765.91" "Revista" => array:6 [ "tituloSerie" => "Sex Transm Dis" "fecha" => "2006" "volumen" => "33" "paginaInicial" => "529" "paginaFinal" => "533" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16540883" "web" => "Medline" ] ] ] ] ] ] ] ] 17 => array:3 [ "identificador" => "bib18" "etiqueta" => "18." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Oral famciclovir for the suppression of recurrent genital herpes: a randomized controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "F. Díaz-Mitoma" 1 => "G. Sibbald" 2 => "S.D. Shafran" 3 => "R. Boon" 4 => "R.L. Saltzman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1998" "volumen" => "280" "paginaInicial" => "887" "paginaFinal" => "892" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9739972" "web" => "Medline" ] ] ] ] ] ] ] ] 18 => array:3 [ "identificador" => "bib19" "etiqueta" => "19." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Valacyclovir for the suppression of recurrent genital herpes simplex virus infection: a large-scale dose range-finding study" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Reitano" 1 => "S. Tyring" 2 => "W. Lang" 3 => "C. Thoming" 4 => "A.M. Worm" 5 => "S. Borelli" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Infect Dis" "fecha" => "1998" "volumen" => "178" "paginaInicial" => "603" "paginaFinal" => "610" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9728526" "web" => "Medline" ] ] ] ] ] ] ] ] 19 => array:3 [ "identificador" => "bib20" "etiqueta" => "20." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Patient-initiated, twice-daily oral famciclovir for early recurrent genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S.L. Sacks" 1 => "F.Y. Aoki" 2 => "F. Díaz-Mitoma" 3 => "J. Sellors" 4 => "S.D. Shafran" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "JAMA" "fecha" => "1996" "volumen" => "276" "paginaInicial" => "44" "paginaFinal" => "49" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8667538" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510710021371" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 20 => array:3 [ "identificador" => "bib21" "etiqueta" => "21." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New approaches to the therapy of HVS infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.J. Whitley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Herpes" "fecha" => "2006" "volumen" => "13" "paginaInicial" => "2" ] ] ] ] ] ] 21 => array:3 [ "identificador" => "bib22" "etiqueta" => "22." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pharmacokinetics of famciclovir in man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "M.A. Pue" 1 => "M.A. Benet" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Antivir Chem Chemother" "fecha" => "1993" "volumen" => "4" "numero" => "Suppl 1" "paginaInicial" => "47" "paginaFinal" => "55" ] ] ] ] ] ] 22 => array:3 [ "identificador" => "bib23" "etiqueta" => "23." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Single-dose, patient-initiated famciclovir: a randomized, double-blind, placebo-controlled trial for episodic treatment of herpes labialis" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S.I. Spruance" 1 => "N. Bodsworth" 2 => "H. Resnick" 3 => "M. Conant" 4 => "C. Oeuvray" 5 => "J. Gao" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaad.2006.02.031" "Revista" => array:6 [ "tituloSerie" => "J Am Acad Dermatol" "fecha" => "2006" "volumen" => "55" "paginaInicial" => "47" "paginaFinal" => "53" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16781291" "web" => "Medline" ] ] ] ] ] ] ] ] 23 => array:3 [ "identificador" => "bib24" "etiqueta" => "24." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Short-course therapy for recurrent genital herpes and herpes labialis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "S. Spruance" 1 => "F.Y. Aoki" 2 => "S. Tyring" 3 => "L. Stanberry" 4 => "R. Whitley" 5 => "K. Hamed" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Fam Pract" "fecha" => "2007" "volumen" => "56" "paginaInicial" => "30" "paginaFinal" => "36" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17217895" "web" => "Medline" ] ] ] ] ] ] ] ] 24 => array:3 [ "identificador" => "bib25" "etiqueta" => "25." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Single-day, patient-initiated famciclovir therapy for recurrent genital herpes: a randomized, double-blind, placebo-controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F.Y. Aoki" 1 => "S. Tyring" 2 => "F. Díaz-Mitoma" 3 => "G. Gross" 4 => "J. Gao" 5 => "K. Hamed" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/498521" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2006" "volumen" => "42" "paginaInicial" => "8" "paginaFinal" => "13" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16323085" "web" => "Medline" ] ] ] ] ] ] ] ] 25 => array:3 [ "identificador" => "bib26" "etiqueta" => "26." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Single-day famciclovir therapy for recurrent genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R. Whitley" 1 => "F. Díaz-Mitoma" 2 => "K. Hamed" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1185/030079906X112642" "Revista" => array:6 [ "tituloSerie" => "Curr Med Res Opin" "fecha" => "2006" "volumen" => "22" "paginaInicial" => "1307" "paginaFinal" => "1310" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16834829" "web" => "Medline" ] ] ] ] ] ] ] ] 26 => array:3 [ "identificador" => "bib27" "etiqueta" => "27." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Famciclovir for the treatment of recurrent genital herpes: a clinical and pharmacological perspective" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D.C. Vinh" 1 => "F.Y. Aoki" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1517/14656566.7.16.2271" "Revista" => array:6 [ "tituloSerie" => "Expert Opin Pharmacother" "fecha" => "2006" "volumen" => "7" "paginaInicial" => "2271" "paginaFinal" => "2286" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17059383" "web" => "Medline" ] ] ] ] ] ] ] ] 27 => array:3 [ "identificador" => "bib28" "etiqueta" => "28." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Famciclovir: a review of its use in herpes zoster and genital and orolabial herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D. Simpson" 1 => "K.A. Lyseng-Williamson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Drugs" "fecha" => "2006" "volumen" => "6" "paginaInicial" => "2397" "paginaFinal" => "2416" "itemHostRev" => array:3 [ "pii" => "S001651071100112X" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 28 => array:3 [ "identificador" => "bib29" "etiqueta" => "29." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of recurrent genital herpes simplex infections with oral acyclovir A controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.C. Reichman" 1 => "G.J. Badger" 2 => "G.J. Mertz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "JAMA" "fecha" => "1984" "volumen" => "251" "paginaInicial" => "2103" "paginaFinal" => "2107" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6368877" "web" => "Medline" ] ] ] ] ] ] ] ] 29 => array:3 [ "identificador" => "bib30" "etiqueta" => "30." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comparison of one year of episodic or suppressive treatment of recurrent genital herpes with valacyclovir" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K.H. Fife" 1 => "J. Almekinder" 2 => "S. Ofner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Sex Trasm Dis" "fecha" => "2007" "volumen" => "34" "paginaInicial" => "297" "paginaFinal" => "301" ] ] ] ] ] ] 30 => array:3 [ "identificador" => "bib31" "etiqueta" => "31." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genital herpes complicating pregnancy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Z.A. Brown" 1 => "C. Gardella" 2 => "A. Wald" 3 => "R.A. Morrow" 4 => "L. Corey" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.AOG.0000180779.35572.3a" "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "2005" "volumen" => "106" "paginaInicial" => "845" "paginaFinal" => "856" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16199646" "web" => "Medline" ] ] ] ] ] ] ] ] 31 => array:3 [ "identificador" => "bib32" "etiqueta" => "32." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Herpes simple zosteriforme neonatal" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J. Del Boz" 1 => "L. Affumicato" 2 => "T. Martín" 3 => "D. Moreno-Pérez" 4 => "A. Vera" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2008" "volumen" => "99" "paginaInicial" => "157" "paginaFinal" => "169" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18346443" "web" => "Medline" ] ] ] ] ] ] ] ] 32 => array:3 [ "identificador" => "bib33" "etiqueta" => "33." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Diagnóstico y diagnóstico diferencial del herpes zóster" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "L. Requena" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr." "fecha" => "2006" "volumen" => "97" "numero" => "Supl 3" "paginaInicial" => "17" "paginaFinal" => "24" ] ] ] ] ] ] 33 => array:3 [ "identificador" => "bib34" "etiqueta" => "34." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preventing herpes simplex virus transmission to the neonate" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Z. Brown" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Herpes" "fecha" => "2004" "volumen" => "11" "numero" => "Suppl 3" "paginaInicial" => "175A" "paginaFinal" => "A186" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15319088" "web" => "Medline" ] ] ] ] ] ] ] ] 34 => array:3 [ "identificador" => "bib35" "etiqueta" => "35." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "Z.A. Brown" 1 => "J. Benedetti" 2 => "R. Ashley" 3 => "S. Burchett" 4 => "S. Selke" 5 => "S. Berry" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199105023241804" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1991" "volumen" => "324" "paginaInicial" => "1247" "paginaFinal" => "1252" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1849612" "web" => "Medline" ] ] ] ] ] ] ] ] 35 => array:3 [ "identificador" => "bib36" "etiqueta" => "36." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The acquisition of herpes simplex virus during pregnancy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "Z.A. Brown" 1 => "S. Selke" 2 => "J. Zeh" 3 => "J. Kopelman" 4 => "A. Maslow" 5 => "R.L. Ashley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM199708213370801" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1997" "volumen" => "337" "paginaInicial" => "509" "paginaFinal" => "515" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9262493" "web" => "Medline" ] ] ] ] ] ] ] ] 36 => array:3 [ "identificador" => "bib37" "etiqueta" => "37." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "HVS-2 specific serology should be offered routinely to antenatal patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Z.A. Brown" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Med Virol" "fecha" => "2000" "volumen" => "10" "paginaInicial" => "141" "paginaFinal" => "144" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10815025" "web" => "Medline" ] ] ] ] ] ] ] ] 37 => array:3 [ "identificador" => "bib38" "etiqueta" => "38." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A double-blind, randomized, placebo-controlled trial of acyclovir in late pregnancy for the reduction of herpes simplex virus shedding and caesarean delivery" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "D.H. Watts" 1 => "Z. Brown" 2 => "D. Money" 3 => "S. Selke" 4 => "M.L. Huang" 5 => "S.L. Sacks" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol" "fecha" => "2003" "volumen" => "188" "paginaInicial" => "836" "paginaFinal" => "843" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12634667" "web" => "Medline" ] ] ] ] ] ] ] ] 38 => array:3 [ "identificador" => "bib39" "etiqueta" => "39." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Pregnancy outcomes following systemic prenatal acyclovir exposure: conclusions from the international acyclovir pregnancy registry, 1984-1989" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "K.M. Stone" 1 => "R. Reiff-Eldridge" 2 => "A.D. White" 3 => "J.F. Cordero" 4 => "Z. Brown" 5 => "E.R. Alexander" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Birth Defects Research (Part A)" "fecha" => "2004" "volumen" => "70" "paginaInicial" => "201" "paginaFinal" => "207" ] ] ] ] ] ] 39 => array:3 [ "identificador" => "bib40" "etiqueta" => "40." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acyclovir prophylaxis to prevent herpes simplex virus recurrence at delivery: a systematic review" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.S. Sheffield" 1 => "L.M. Hollier" 2 => "J.B. Hill" 3 => "G.S. Stuart" 4 => "G.D. Wendel Jr" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "2003" "volumen" => "102" "paginaInicial" => "1396" "paginaFinal" => "1403" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14662233" "web" => "Medline" ] ] ] ] ] ] ] ] 40 => array:3 [ "identificador" => "bib41" "etiqueta" => "41." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acyclovir suppression to prevent genital recurrent herpes at delivery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "L.L. Scott" 1 => "L.M. Hollier" 2 => "D. McIntire" 3 => "P.J. Sánchez" 4 => "G.L. Jackson" 5 => "G.D. Wendel Jr" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1155/S1064744902000054" "Revista" => array:6 [ "tituloSerie" => "Infect Dis Obstet Gynecol" "fecha" => "2002" "volumen" => "10" "paginaInicial" => "71" "paginaFinal" => "77" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12530483" "web" => "Medline" ] ] ] ] ] ] ] ] 41 => array:3 [ "identificador" => "bib42" "etiqueta" => "42." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Valacyclovir prophylaxis to prevent recurrent herpes at delivery: a randomized clinical trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.S. Sheffield" 1 => "J.B. Hill" 2 => "L.M. Hollier" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/01.AOG.0000219749.96274.15" "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "2006" "volumen" => "108" "paginaInicial" => "141" "paginaFinal" => "147" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16816068" "web" => "Medline" ] ] ] ] ] ] ] ] 42 => array:3 [ "identificador" => "bib43" "etiqueta" => "43." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Valacyclovir therapy to reduce recurrent genital herpes in pregnant women" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "W.W. Andrews" 1 => "D.F. Kimberlin" 2 => "R. Whitley" 3 => "S. Cliver" 4 => "P.S. Ramsey" 5 => "R. Deeter" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ajog.2005.11.051" "Revista" => array:6 [ "tituloSerie" => "Am J Obstet Gynecol." "fecha" => "2006" "volumen" => "194" "paginaInicial" => "774" "paginaFinal" => "781" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16522412" "web" => "Medline" ] ] ] ] ] ] ] ] 43 => array:3 [ "identificador" => "bib44" "etiqueta" => "44." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neonatal herpes in Denmark 1977-1991" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "G. Fonnest" 1 => "de la Fuente" 2 => "I. Fonnest" 3 => "T. Weber" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Obstet Gynecol Scand" "fecha" => "1997" "volumen" => "76" "paginaInicial" => "335" "paginaFinal" => "358" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9174427" "web" => "Medline" ] ] ] ] ] ] ] ] 44 => array:3 [ "identificador" => "bib45" "etiqueta" => "45." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of neonatal herpes simplex virus infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A.M. Kesson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Paediatr Drugs" "fecha" => "2001" "volumen" => "3" "paginaInicial" => "81" "paginaFinal" => "90" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11269641" "web" => "Medline" ] ] ] ] ] ] ] ] 45 => array:3 [ "identificador" => "bib46" "etiqueta" => "46." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acyclovir suppression to prevent caesarean delivery after first-episode genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L.L. Scott" 1 => "P.J. Sánchez" 2 => "G.L. Jackson" 3 => "F. Zeray" 4 => "G.D. Wendel" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Obstet Gynecol" "fecha" => "1996" "volumen" => "87" "paginaInicial" => "69" "paginaFinal" => "73" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8532270" "web" => "Medline" ] ] ] ] ] ] ] ] 46 => array:3 [ "identificador" => "bib47" "etiqueta" => "47." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acyclovir prophylaxis in late pregnancy prevents recurrent genital herpes and viral shedding" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "S. Braig" 1 => "D. Luton" 2 => "O. Sibony" 3 => "C. Edlinger" 4 => "C. Boissinot" 5 => "P. Blot" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eur J Obstet Gynecol Reprod Biol" "fecha" => "2001" "volumen" => "96" "paginaInicial" => "55" "paginaFinal" => "58" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11311761" "web" => "Medline" ] ] ] ] ] ] ] ] 47 => array:3 [ "identificador" => "bib48" "etiqueta" => "48." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neonatal herpes simplex virus infection introduced by fetal-monitor scalp electrodes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "L.S. Parvey" 1 => "L.T. Chien" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Pediatrics" "fecha" => "1980" "volumen" => "65" "paginaInicial" => "150" "paginaFinal" => "153" ] ] ] ] ] ] 48 => array:3 [ "identificador" => "bib49" "etiqueta" => "49." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Herpes simplex and varicella-zoster virus infections during pregnancy: current concepts of prevention, diagnosis and therapy. Part 1: Herpes simplex virus infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Sauerbrei" 1 => "P. Wutzler" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00430-006-0032-z" "Revista" => array:6 [ "tituloSerie" => "Med Microbiol Immunol" "fecha" => "2007" "volumen" => "196" "paginaInicial" => "95" "paginaFinal" => "102" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17180380" "web" => "Medline" ] ] ] ] ] ] ] ] 49 => array:3 [ "identificador" => "bib50" "etiqueta" => "50." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Low risk of herpes simplex virus infections in neonates exposed to the virus at the time of vaginal delivery to mothers with recurrent genital herpes simplex virus infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C.G. Prober" 1 => "W.M. Sullender" 2 => "L.L. Yasukawa" 3 => "D.S. Au" 4 => "A.S. Yeager" 5 => "A.M. Arvin" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJM198701293160503" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "1987" "volumen" => "316" "paginaInicial" => "240" "paginaFinal" => "244" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3025727" "web" => "Medline" ] ] ] ] ] ] ] ] 50 => array:3 [ "identificador" => "bib51" "etiqueta" => "51." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Strategies for the prevention of neonatal infection with herpes simplex virus: a decision analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M.D. Libman" 1 => "A. Dascal" 2 => "M.S. Kramer" 3 => "J. Mendelson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Rev Infect Dis" "fecha" => "1991" "volumen" => "13" "paginaInicial" => "1093" "paginaFinal" => "1104" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1663650" "web" => "Medline" ] ] ] ] ] ] ] ] 51 => array:3 [ "identificador" => "bib52" "etiqueta" => "52." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Intrauterine herpes simplex virus infections" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C. Hutto" 1 => "A. Arvin" 2 => "R. Jacobs" 3 => "R. Steele" 4 => "S. Stagno" 5 => "R. Lyrene" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Pediatr" "fecha" => "1987" "volumen" => "110" "paginaInicial" => "97" "paginaFinal" => "101" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3794894" "web" => "Medline" ] ] ] ] ] ] ] ] 52 => array:3 [ "identificador" => "bib53" "etiqueta" => "53." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Genital primary herpetic infection in an infant: clinical features, diagnosis and management" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "R.K. Khaddar" 1 => "T. Bradri" 2 => "A. Ben Hassen" 3 => "S. Bouraouri" 4 => "A Souissi" 5 => "N. Ben Tekaya" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Dermatol Online J" "fecha" => "2005" "volumen" => "11" "paginaInicial" => "22" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16409918" "web" => "Medline" ] ] ] ] ] ] ] ] 53 => array:3 [ "identificador" => "bib54" "etiqueta" => "54." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical epidemiology of symptomatic primary herpetic infection in children A study of 50 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "A. Taieb" 1 => "S. Body" 2 => "I. Astar" 3 => "P. DuPasquier" 4 => "J. Maleville" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Acta Paediatr Scand" "fecha" => "1987" "volumen" => "76" "paginaInicial" => "128" "paginaFinal" => "132" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3031926" "web" => "Medline" ] ] ] ] ] ] ] ] 54 => array:3 [ "identificador" => "bib55" "etiqueta" => "55." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Childhood sexually transmited diseases: one consequence of sexual abuse" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C. Anderson" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Public Health Nurs" "fecha" => "1995" "volumen" => "12" "paginaInicial" => "41" "paginaFinal" => "46" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7899223" "web" => "Medline" ] ] ] ] ] ] ] ] 55 => array:3 [ "identificador" => "bib56" "etiqueta" => "56." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Relationship between herpes simplex virus ulceration and CD4 cell counts in patients with HIV infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "E.K. Bagdades" 1 => "D. Pillay" 2 => "S.B. Squire" 3 => "C. O’Neil" 4 => "M.A. Johnson" 5 => "P.D. Griffiths" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "AIDS" "fecha" => "1992" "volumen" => "6" "paginaInicial" => "1317" "paginaFinal" => "1320" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1361745" "web" => "Medline" ] ] ] ] ] ] ] ] 56 => array:3 [ "identificador" => "bib57" "etiqueta" => "57." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Management of herpes simplex virus type 2 infection in VIH type 1-infected presons" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.B. Strick" 1 => "A. Wald" 2 => "C. Celum" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/505496" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2006" "volumen" => "43" "paginaInicial" => "347" "paginaFinal" => "356" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16804851" "web" => "Medline" ] ] ] ] ] ] ] ] 57 => array:3 [ "identificador" => "bib58" "etiqueta" => "58." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Epidemiology of genital herpes infections" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "G.J. Mertz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Infect Dis Clin North Am." "fecha" => "1993" "volumen" => "7" "paginaInicial" => "825" "paginaFinal" => "839" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8106731" "web" => "Medline" ] ] ] ] ] ] ] ] 58 => array:3 [ "identificador" => "bib59" "etiqueta" => "59." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "High accumulative incidence of genital herpes amongst HIV-1 seropositive heterosexuals in south London" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "N. O’Farrell" 1 => "S.J. Tovey" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J STD AIDS." "fecha" => "1994" "volumen" => "5" "paginaInicial" => "415" "paginaFinal" => "418" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7849119" "web" => "Medline" ] ] ] ] ] ] ] ] 59 => array:3 [ "identificador" => "bib60" "etiqueta" => "60." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Co-infection and synergy of human immunodeficiency virus-1 and herpes simplex virus-1" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M.C. Heng" 1 => "S.Y. Heng" 2 => "S.G. Allen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lancet" "fecha" => "1994" "volumen" => "343" "paginaInicial" => "255" "paginaFinal" => "258" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7905094" "web" => "Medline" ] ] ] ] ] ] ] ] 60 => array:3 [ "identificador" => "bib61" "etiqueta" => "61." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Verucous lesions of herpes simplex in HIV-1 patients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "P. Vogel" 1 => "K.J. Smith" 2 => "H.G. Skeleton" 3 => "D. Cuozzo" 4 => "K.F. Wagner" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Dermatol" "fecha" => "1993" "volumen" => "32" "paginaInicial" => "680" "paginaFinal" => "682" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8407100" "web" => "Medline" ] ] ] ] ] ] ] ] 61 => array:3 [ "identificador" => "bib62" "etiqueta" => "62." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Úlceras herpéticas perianales en un paciente con infección por el virus de inmunodeficiencia humana no diagnosticado previamente" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "B. Monteagudo" 1 => "V.M. López-Mouriño" 2 => "P. Ordóñez" 3 => "C. Durana" 4 => "C. de las Heras" 5 => "J.M. Cacharrón" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Actas Dermosifiliogr" "fecha" => "2006" "volumen" => "97" "paginaInicial" => "479" "paginaFinal" => "480" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16978553" "web" => "Medline" ] ] ] ] ] ] ] ] 62 => array:3 [ "identificador" => "bib63" "etiqueta" => "63." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased incidence of genital herpes after HAART initiation: a frequent presentation of immune reconstitution inflammatory syndrome (IRIS) in VIH-infected patients" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "P. Couppie" 1 => "F. Sarazin" 2 => "E. Clyti" 3 => "M. El Guedj" 4 => "T. Vaz" 5 => "E. Clyti" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1089/apc.2006.20.143" "Revista" => array:6 [ "tituloSerie" => "AIDS Patient Care STDS" "fecha" => "2006" "volumen" => "20" "paginaInicial" => "143" "paginaFinal" => "145" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16548710" "web" => "Medline" ] ] ] ] ] ] ] ] 63 => array:3 [ "identificador" => "bib64" "etiqueta" => "64." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Increased genital shedding of herpes-simplex virus type 2 in HIV-women" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Augenbraun" 1 => "J. Feldman" 2 => "K. Chirgwin" 3 => "J. Zenilman" 4 => "L. Clarke" 5 => "J. De Hovitz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Ann Intern Med" "fecha" => "1995" "volumen" => "123" "paginaInicial" => "845" "paginaFinal" => "847" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7486467" "web" => "Medline" ] ] ] ] ] ] ] ] 64 => array:3 [ "identificador" => "bib65" "etiqueta" => "65." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Recurrence and resistance patterns of herpes simplex virus following cessation of >or=6 years suppression with acyclovir. Acyclovir Study Group" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "K.H. File" 1 => "C.S. Crumpacker" 2 => "G.J. Mertz" 3 => "E.L. Hill" 4 => "G.S. Boone" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Infect Dis" "fecha" => "1994" "volumen" => "169" "paginaInicial" => "1338" "paginaFinal" => "1341" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8195614" "web" => "Medline" ] ] ] ] ] ] ] ] 65 => array:3 [ "identificador" => "bib66" "etiqueta" => "66." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Sexually transmitted diseases treatment guidelines 2002" "autores" => array:1 [ 0 => array:2 [ "colaboracion" => "Centers for Disease Control Prevention" "etal" => false ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "MMWR" "fecha" => "2002" "volumen" => "51" "paginaInicial" => "1" "paginaFinal" => "84" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15580804" "web" => "Medline" ] ] ] ] ] ] ] ] 66 => array:3 [ "identificador" => "bib67" "etiqueta" => "67." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Infection in solid organ transplantation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.R. Snydman" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Transpl Infect Dis" "fecha" => "1999" "volumen" => "1" "paginaInicial" => "21" "paginaFinal" => "28" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11428968" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S001651070702278X" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 67 => array:3 [ "identificador" => "bib68" "etiqueta" => "68." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Preventing opportunistic infections in bone marrow transplant recipients" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.A. Dykewicz" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Transpl Infect Dis" "fecha" => "1999" "volumen" => "1" "paginaInicial" => "40" "paginaFinal" => "49" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11565587" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1474442210702234" "estado" => "S300" "issn" => "14744422" ] ] ] ] ] ] ] 68 => array:3 [ "identificador" => "bib69" "etiqueta" => "69." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Antiviral prophylaxis with continuous low dose acyclovir in childhood cancer" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Celkan" 1 => "A. Ozkan" 2 => "H. Apak" 3 => "I. Ildiz" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1080/10428190600581682" "Revista" => array:6 [ "tituloSerie" => "Leuk Lymphoma" "fecha" => "2006" "volumen" => "47" "paginaInicial" => "1418" "paginaFinal" => "1420" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16923583" "web" => "Medline" ] ] ] ] ] ] ] ] 69 => array:3 [ "identificador" => "bib70" "etiqueta" => "70." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Topically administered acyclovir in the treatment of recurrent herpes simplex genitalis: a controlled trial" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "R.C. Reichman" 1 => "G.J. Badger" 2 => "M.E. Guinan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Infect Dis" "fecha" => "1983" "volumen" => "147" "paginaInicial" => "336" "paginaFinal" => "340" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6298318" "web" => "Medline" ] ] ] ] ] ] ] ] 70 => array:3 [ "identificador" => "bib71" "etiqueta" => "71." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Selective defect in plasmacyoid dendritic cell function in a patient with AIDS-associated atypical genital herpes simplex vegetans treated with imiquimod" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "L. Abbo" 1 => "V. Vicek" 2 => "G. Dickinson" 3 => "N. Shresthe" 4 => "S. Doblecki" 5 => "P.A. Haslett" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/510426" "Revista" => array:6 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2007" "volumen" => "44" "paginaInicial" => "e25" "paginaFinal" => "e27" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17205432" "web" => "Medline" ] ] ] ] ] ] ] ] 71 => array:3 [ "identificador" => "bib72" "etiqueta" => "72." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Imiquimod 5% cream for the treatment of recurrent, acyclovir-resistant genital herpes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.F. Brummitt" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1086/499529" "Revista" => array:5 [ "tituloSerie" => "Clin Infect Dis" "fecha" => "2006" "volumen" => "42" "paginaInicial" => "575" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16421805" "web" => "Medline" ] ] ] ] ] ] ] ] 72 => array:3 [ "identificador" => "bib73" "etiqueta" => "73." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Topical imiquimod for acyclovir-unresponsive herpes simplex virus 2 infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J. Gilbert" 1 => "M.M. Drehs" 2 => "J.M. Weinberg" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Dermatol" "fecha" => "2001" "volumen" => "137" "paginaInicial" => "1015" "paginaFinal" => "1017" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11493093" "web" => "Medline" ] ] ] ] ] ] ] ] 73 => array:3 [ "identificador" => "bib74" "etiqueta" => "74." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Imiquimod 5-percent cream does not alter the natural history of recurrent herpes genitalis: a phase II, randomized, double-blind, placebo-controlled study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "T.W. Schacker" 1 => "M. Conant" 2 => "C. Thoming" 3 => "T. Stanczak" 4 => "Z. Wang" 5 => "M. Smith" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Antimicrob Agents Chemother" "fecha" => "2002" "volumen" => "46" "paginaInicial" => "3243" "paginaFinal" => "3248" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12234851" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0016510708029519" "estado" => "S300" "issn" => "00165107" ] ] ] ] ] ] ] 74 => array:3 [ "identificador" => "bib75" "etiqueta" => "75." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of mucocutaneous herpes simplex virus infections unresponsive to acyclovir with topical foscarnet cream in AIDS patients: a phase I/II study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K. Javaly" 1 => "M. Wohlfeiler" 2 => "R. Kalayjian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Acquir Immune Defic Syndr" "fecha" => "1999" "volumen" => "21" "paginaInicial" => "301" "paginaFinal" => "306" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10428108" "web" => "Medline" ] ] ] ] ] ] ] ] 75 => array:3 [ "identificador" => "bib76" "etiqueta" => "76." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Chronic hypertrophic acyclovir-resistant genital herpes treated with topical cidofovir and with topical foscarnet at recurrence in an VIH-positive man" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Ghislanzoni" 1 => "M. Cusini" 2 => "R. Zerboni" 3 => "E. Alessi" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1468-3083.2006.01561.x" "Revista" => array:6 [ "tituloSerie" => "J Eur Acad Dermatol Venereol" "fecha" => "2006" "volumen" => "20" "paginaInicial" => "887" "paginaFinal" => "889" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16898926" "web" => "Medline" ] ] ] ] ] ] ] ] 76 => array:3 [ "identificador" => "bib77" "etiqueta" => "77." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Treatment of acyclovir-resistant herpetic ulceration with topical foscarnet and antiviral sensitivity analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "M. Pechere" 1 => "W. Wunderly" 2 => "L. Trellu-Toutous" 3 => "M. Harms" 4 => "J.H. Saura" 5 => "J. Krischer" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Dermatology" "fecha" => "1998" "volumen" => "197" "paginaInicial" => "278" "paginaFinal" => "280" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9812037" "web" => "Medline" ] ] ] ] ] ] ] ] 77 => array:3 [ "identificador" => "bib78" "etiqueta" => "78." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Acyclovir resistance/susceptibility in herpessimplex virus type 2 sequential isolates from an AIDS patient" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "F. Bevilacqua" 1 => "A. Marcello" 2 => "M. Toni" 3 => "M. Zavattoni" 4 => "M. Cusini" 5 => "R. Zerboni" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Acquir Immune Defic Syndr" "fecha" => "1991" "volumen" => "4" "paginaInicial" => "967" "paginaFinal" => "969" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1832460" "web" => "Medline" ] ] ] ] ] ] ] ] 78 => array:3 [ "identificador" => "bib79" "etiqueta" => "79." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Betadine for herpes simplex infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.J. Waters" 1 => "S.E. Barton" 2 => "F.C. Boag" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1258/095646206779307487" "Revista" => array:6 [ "tituloSerie" => "Int J STD AIDS" "fecha" => "2006" "volumen" => "17" "paginaInicial" => "854" "paginaFinal" => "855" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17212866" "web" => "Medline" ] ] ] ] ] ] ] ] 79 => array:3 [ "identificador" => "bib80" "etiqueta" => "80." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An si-RNA-based microbicide protects mice from lethal herpes simplex virus 2 infection" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "D. Palliser" 1 => "D. Chowdhury" 2 => "Q.Y. Wang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/nature04263" "Revista" => array:6 [ "tituloSerie" => "Nature" "fecha" => "2006" "volumen" => "439" "paginaInicial" => "89" "paginaFinal" => "94" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16306938" "web" => "Medline" ] ] ] ] ] ] ] ] 80 => array:3 [ "identificador" => "bib81" "etiqueta" => "81." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Silencing herpes simplex virus with a vaginal microbicide" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "D.C. Johnson" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1056/NEJMcibr055613" "Revista" => array:6 [ "tituloSerie" => "N Engl J Med" "fecha" => "2006" "volumen" => "354" "paginaInicial" => "970" "paginaFinal" => "971" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16510753" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/15782190/0000010000000001/v1_201304241446/S157821900970006X/v1_201304241446/en/main.assets" "Apartado" => array:4 [ "identificador" => "6230" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Advances in dermatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/15782190/0000010000000001/v1_201304241446/S157821900970006X/v1_201304241446/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S157821900970006X?idApp=UINPBA000044" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 6 | 45 | 51 |
2024 October | 64 | 204 | 268 |
2024 September | 66 | 94 | 160 |
2024 August | 88 | 129 | 217 |
2024 July | 62 | 115 | 177 |
2024 June | 88 | 123 | 211 |
2024 May | 69 | 166 | 235 |
2024 April | 66 | 115 | 181 |
2024 March | 68 | 107 | 175 |
2024 February | 60 | 141 | 201 |
2024 January | 65 | 168 | 233 |
2023 December | 73 | 141 | 214 |
2023 November | 74 | 201 | 275 |
2023 October | 68 | 95 | 163 |
2023 September | 53 | 83 | 136 |
2023 August | 53 | 51 | 104 |
2023 July | 44 | 103 | 147 |
2023 June | 49 | 72 | 121 |
2023 May | 56 | 70 | 126 |
2023 April | 37 | 56 | 93 |
2023 March | 61 | 38 | 99 |
2023 February | 52 | 33 | 85 |
2023 January | 40 | 49 | 89 |
2022 December | 28 | 35 | 63 |
2022 November | 19 | 33 | 52 |
2022 October | 26 | 39 | 65 |
2022 September | 15 | 74 | 89 |
2022 August | 19 | 39 | 58 |
2022 July | 24 | 37 | 61 |
2022 June | 21 | 27 | 48 |
2022 May | 22 | 56 | 78 |
2022 April | 55 | 63 | 118 |
2022 March | 69 | 64 | 133 |
2022 February | 30 | 42 | 72 |
2022 January | 35 | 41 | 76 |
2021 December | 24 | 38 | 62 |
2021 November | 31 | 46 | 77 |
2021 October | 33 | 59 | 92 |
2021 September | 37 | 41 | 78 |
2021 August | 37 | 29 | 66 |
2021 July | 56 | 33 | 89 |
2021 June | 27 | 41 | 68 |
2021 May | 24 | 32 | 56 |
2021 April | 41 | 81 | 122 |
2021 March | 55 | 32 | 87 |
2021 February | 56 | 25 | 81 |
2021 January | 35 | 33 | 68 |
2020 December | 27 | 19 | 46 |
2020 November | 24 | 21 | 45 |
2020 October | 31 | 15 | 46 |
2020 September | 22 | 6 | 28 |
2020 August | 21 | 19 | 40 |
2020 July | 23 | 13 | 36 |
2020 June | 28 | 26 | 54 |
2020 May | 22 | 18 | 40 |
2020 April | 19 | 17 | 36 |
2020 March | 27 | 22 | 49 |
2020 February | 0 | 2 | 2 |
2020 January | 0 | 6 | 6 |
2019 December | 0 | 13 | 13 |
2019 November | 0 | 3 | 3 |
2019 October | 0 | 2 | 2 |
2019 September | 0 | 7 | 7 |
2019 August | 0 | 2 | 2 |
2019 July | 0 | 9 | 9 |
2019 June | 0 | 16 | 16 |
2019 May | 0 | 44 | 44 |
2019 April | 0 | 2 | 2 |
2019 March | 0 | 3 | 3 |
2019 February | 0 | 1 | 1 |
2018 May | 0 | 1 | 1 |
2018 April | 0 | 1 | 1 |
2018 March | 2 | 2 | 4 |
2018 February | 11 | 10 | 21 |
2018 January | 14 | 14 | 28 |
2017 December | 11 | 14 | 25 |
2017 November | 19 | 16 | 35 |
2017 October | 22 | 20 | 42 |
2017 September | 17 | 7 | 24 |
2017 August | 31 | 9 | 40 |
2017 July | 26 | 6 | 32 |
2017 June | 37 | 12 | 49 |
2017 May | 39 | 10 | 49 |
2017 April | 46 | 9 | 55 |
2017 March | 55 | 19 | 74 |
2017 February | 22 | 11 | 33 |
2017 January | 19 | 11 | 30 |
2016 December | 49 | 13 | 62 |
2016 November | 25 | 7 | 32 |
2016 October | 29 | 17 | 46 |
2016 September | 32 | 18 | 50 |
2016 August | 35 | 9 | 44 |
2016 July | 29 | 11 | 40 |
2016 June | 14 | 10 | 24 |
2016 May | 9 | 8 | 17 |
2016 April | 11 | 12 | 23 |
2016 March | 6 | 8 | 14 |
2016 February | 14 | 2 | 16 |
2016 January | 9 | 9 | 18 |
2015 December | 10 | 7 | 17 |
2015 November | 12 | 10 | 22 |
2015 October | 17 | 18 | 35 |
2015 September | 6 | 4 | 10 |
2015 August | 24 | 5 | 29 |
2015 July | 49 | 9 | 58 |
2015 June | 55 | 15 | 70 |
2015 May | 116 | 41 | 157 |
2015 April | 59 | 26 | 85 |
2015 March | 53 | 23 | 76 |
2015 February | 39 | 15 | 54 |
2015 January | 41 | 11 | 52 |
2014 December | 48 | 15 | 63 |
2014 November | 36 | 15 | 51 |
2014 October | 62 | 34 | 96 |
2014 September | 65 | 32 | 97 |
2014 August | 65 | 23 | 88 |
2014 July | 92 | 23 | 115 |
2014 June | 92 | 20 | 112 |
2014 May | 75 | 20 | 95 |
2014 April | 48 | 7 | 55 |
2014 March | 43 | 23 | 66 |
2014 February | 27 | 26 | 53 |
2014 January | 42 | 25 | 67 |
2013 December | 41 | 23 | 64 |
2013 November | 28 | 29 | 57 |
2013 October | 40 | 30 | 70 |
2013 September | 36 | 28 | 64 |
2013 August | 44 | 54 | 98 |
2013 July | 45 | 46 | 91 |
2013 June | 42 | 40 | 82 |
2013 May | 47 | 30 | 77 |
2013 April | 46 | 38 | 84 |
2013 March | 56 | 40 | 96 |
2013 February | 61 | 17 | 78 |
2013 January | 25 | 5 | 30 |