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B) Nódulos escabióticos. C) Imagen dermatoscópica del <span class="elsevierStyleItalic">Sarcoptes scabiei var hominis</span>, la flecha señala el ácaro.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "P.A. Cerro, A. Navarro-Bielsa, A.M. Palma" "autores" => array:3 [ 0 => array:2 [ "nombre" => "P.A." "apellidos" => "Cerro" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Navarro-Bielsa" ] 2 => array:2 [ "nombre" => "A.M." 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Linares-Gonzalez, T. Ródenas-Herranz, R. Ruiz-Villaverde" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Linares-Gonzalez" ] 1 => array:2 [ "nombre" => "T." "apellidos" => "Ródenas-Herranz" ] 2 => array:2 [ "nombre" => "R." "apellidos" => "Ruiz-Villaverde" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731021003173?idApp=UINPBA000044" "url" => "/00017310/0000011300000005/v1_202206110542/S0001731021003173/v1_202206110542/es/main.assets" ] ] "en" => array:12 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Dermatology</span>" "titulo" => " Spiny Keratoderma as a Paraneoplastic Condition in Clear Cell Renal Cell Carcinoma" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "T514" "paginaFinal" => "T515" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "L. Linares-Gonzalez, T. Ródenas-Herranz, R. Ruiz-Villaverde" "autores" => array:3 [ 0 => array:2 [ "nombre" => "L." "apellidos" => "Linares-Gonzalez" ] 1 => array:2 [ "nombre" => "T." "apellidos" => "Ródenas-Herranz" ] 2 => array:4 [ "nombre" => "R." "apellidos" => "Ruiz-Villaverde" "email" => array:1 [ 0 => "ismenios@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Queratodermia espinulosa, una condición paraneoplásica de un carcinoma renal de células claras" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 848 "Ancho" => 1251 "Tamanyo" => 144440 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 67-year-old man with a past history of resected basal cell carcinoma, high blood pressure, and diabetes mellitus was referred to our dermatology department for assessment of lesions on the hands that had appeared 3 months earlier. Physical examination revealed multiple keratotic spines measuring 1<span class="elsevierStyleHsp" style=""></span>mm on the palmar surface of both hands (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B). Examination of the rest of the skin surface revealed no other significant abnormalities. The patient reported no constitutional symptoms or associated systemic symptoms. With a clinical diagnosis of spiny keratoderma and given that this is considered to be a paraneoplastic skin condition, we performed a battery of tests, which were negative, and full-body computed tomography, which revealed a solid cortical nodule with a maximum diameter of 2<span class="elsevierStyleHsp" style=""></span>cm in the left kidney (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>); the nodule was resected and histology was compatible with clear cell renal cell carcinoma.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Spiny keratoderma is rarely reported in the literature and is associated with diabetes mellitus, chronic kidney failure, and different tumors, including esophageal carcinoma, laryngeal squamous cell carcinoma, malignant melanoma, and lung adenocarcinoma. In most cases, its appearance has preceded development of the tumor, although it has not been possible to demonstrate a causal relationship in all cases. Its asymptomatic nature means that it may go unnoticed. Treatment with topical and systematic keratolytic agents achieves an uneven response.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 848 "Ancho" => 1251 "Tamanyo" => 144440 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1025 "Ancho" => 961 "Tamanyo" => 97745 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/00017310/0000011300000005/v1_202206110542/S0001731022002836/v1_202206110542/en/main.assets" "Apartado" => array:4 [ "identificador" => "93052" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes en Dermatología / Images in Dermatologylogía" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00017310/0000011300000005/v1_202206110542/S0001731022002836/v1_202206110542/en/main.pdf?idApp=UINPBA000044&text.app=https://actasdermo.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0001731022002836?idApp=UINPBA000044" ]
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