Journal Information
Vol. 100. Issue S2.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte II
Pages 84-87 (December 2009)
Vol. 100. Issue S2.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte II
Pages 84-87 (December 2009)
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DNA Polymorphisms: What They Are and Their Role in Human Pigmentation
Polimorfismos de adn: qué son y su rol en la pigmentación humana
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M.G. Kosmadaki, A.J. Stratigos, Ch. Antoniou, A. Katsambas
Corresponding author
Andreas Sygros Hospital. University of Athens. Greece
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Abstract

The color of the skin, hair and eye is controlled by multiple genes and is among the most visible examples of human phenotypic variation. Genetics correlate phenotypic with genotypic variation. Recent scientific work reveals DNA polymorphisms at least partially responsible for some of the differences observed in human pigmentation. These are the focus of this review.

Key words:
single nucleotide polymorphism
polymorphisms
pigmentation
Resumen

El color de la piel, el pelo y los ojos está controlado por múltiples genes y es uno de los ejemplos más visibles de la variabilidad fenotípica humana. La genética correlaciona la variabilidad fenotípica con la genotípica. Recientes publicaciones científicas revelan que los polimorfismos del ADN son responsables, al menos parcialmente, de algunas de las diferencias observadas en la pigmentación humana. Éstas serán el objetivo de la presente revisión.

Palabras clave:
polimorfismos de nucleótido único
polimorfismos
pigmentación
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