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Vol. 100. Núm. S1.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte I
Páginas 33-37 (Noviembre 2009)
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Vol. 100. Núm. S1.
Mirando hacia el futuro en Dermatología Extraordinario del Centenario. Parte I
Páginas 33-37 (Noviembre 2009)
Acceso a texto completo
The Uncertain Status of Cutaneous Pseudolymphoma
El estado incierto del pseudolinfoma cutáneo
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H. Bachelez
Autor para correspondencia
herve.bachelez@sls.aphp.fr

Correspondence: Hervé Bachelez. Service de Dermatologie. Hôpital Saint-Louis. 1, avenue Claude Vellefaux. 75475 Paris cedex 10.
Department of Dermatology. Hôpital Saint-Louis, AP-HP. Université Paris 7. France
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Abstract

Cutaneous pseudolymphomas (CPLs) include a wide range of clinicopathological presentations sharing in common the presence of clinical and histopathological features mimicking those of primary cutaneous lymphomas. Although immunophenotypical studies and molecular analysis of clonality have been shown to be reliable tools, providing significant help in the differential diagnosis between primary cutaneous lymphoid malignancy and pseudolymphoma involving the skin, the identification of an etiological agent and prolonged follow-up remain the key steps to ascertain the benign, reactive nature of a skin lymphocytic infiltrate.

Key words:
pseudolymphoma
acquired immunodeficiency syndrome
Resumen

Los pseudolinfomas cutáneos incluyen una amplia gama de presentaciones clínico-histológicas que tienen en común la presencia de características clínicas e histológicas que remedan a las de los linfomas cutáneos primarios.

Aunque los estudios inmunofenotípicos y el análisis molecular de clonalidad han demostrado ser técnicas fiables, que facilitan de forma significativa el diagnóstico diferencial entre neoplasia linfoide cutánea primaria y pseudolinfoma, la clave para identificar la naturaleza benigna y reactiva de un infiltrado linfocítico cutáneo estriba en la identificación de un agente causal y un periodo de seguimiento prolongado.

Palabras clave:
pseudolinfoma
síndrome de inmunodeficiencia adquirida
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