Actas Dermo-Sifiliográficas (English Edition) Actas Dermo-Sifiliográficas (English Edition)
The Value of Adjuvant Radiotherapy in Cutaneous Squamous Cell Carcinoma: A Review
Utilidad de la radioterapia en adyuvancia en el carcinoma epidermoide cutáneo
J. Cañuetoa, A. Jakab, A. Tollc,,
a Servicio de Dermatología, Complejo Asistencial Universitario de Salamanca, IBSAL Instituto de Investigación Biomédica de Salamanca, Complejo Asistencial Universitario de Salamanca, Salamanca, España
b Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Badalona, España
c Servicio de Dermatología, Hospital del Mar, Parc de Salut Mar, Barcelona, España
Received 18 December 2017, Accepted 19 March 2018

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans and its incidence is rising. Although surgery is the treatment of choice for cSCC, postoperative adjuvant radiotherapy has an important role in local and locorregional disease control. In this review, we analyze the value of postoperative radiotherapy in the management of high-risk cSCC (in particular, cases with perineural invasion), cSCC with positive surgical margins, and locally advanced cSCC (with parotid gland and/or lymph node metastasis).


El carcinoma epidermoide cutáneo (CEC) es el segundo tumor más frecuente en humanos y tiene una incidencia creciente. Aunque la cirugía representa el tratamiento de elección del CEC, la radioterapia adyuvante postoperatoria tiene un papel relevante en el control local y locorregional de la enfermedad. En esta revisión analizamos la utilidad de la radioterapia postoperatoria en el manejo del CEC de alto riesgo (especialmente con infiltración perineural), en el control del CEC con márgenes positivos tras la cirugía y en el CEC localmente avanzado (con metástasis parotídeas o ganglionares).

Cutaneous squamous cell carcinoma, Radiotherapy, Adjuvant, Postoperative, High-risk
Palabras clave
Carcinoma escamoso cutáneo, Radioterapia, Adyuvancia, Postoperatorio, Alto riesgo


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